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All Journal Jurnal Sains dan Teknologi Dinamisia: Jurnal Pengabdian Kepada Masyarakat Jurnal Kartika Kimia Pharmacoscript Jurnal IPTEK Bagi Masyarakat Jurnal Pengabdian Pada Masyarakat
Ernawati, Eneng Elda
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Standardisasi Ekstrak Buah Ceremai (Phyllanthus Acidus L. Skeels) dan Aktivitas Inhibisi Enzim Elastase Ernawati, Eneng Elda; Suryani, Nani; Nuramalia, Sifa; Anisah, Anisah; Yustika, Rd. Widya
Jurnal Kartika Kimia Vol 6 No 2 (2023): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v6i2.225

Abstract

One way to ensure that efficacy and quality are guaranteed is that a product/medicinal ingredient quality standard needs to be met by standardizing the extract. Ceremai fruit (Phyllantus acidus) is thought to have elastase enzyme inhibitor activity because it contains vitamin C and flavonoids. The elastase enzyme functions in skin elasticity. This research aims to determine the standardization of ceremai fruit extract (P. acidus) and the inhibitory activity of the elastase enzyme. The sample was extracted using the maceration method using 70% solvent. Parameters in determining extract standardization are specific and non-specific. The inhibitory activity of the elastase enzyme was analyzed using the ELISA method. The results of determining the standardization of extract-specific parameters, the water-soluble essence content was 65.57%, and the ethanol-soluble essence content was 27.875. Non-specific parameters for determining water content 9.17%, determining total ash content 5.68%, determining acid insoluble ash content 1.5%, determining residual solvent 0.01%, determining microbial contamination ALT and AKK 10-1, heavy metal examination with undetectable results. Ceremai fruit extract (EBC) is positive for containing flavonoids, tannins, saponins, alkaloids, steroids, and phenolic compounds. The elastase enzyme inhibitory activity of ceremai fruit extract (EBC) resulted in an average IC50 value of 281.09 ± 11,3µg/mL and retinol with an average IC50 value of 23.81 ± 0,4 µg/mL. This research concludes that based on standardization testing of specific and non-specific parameters, ceremai fruit extract meets raw material quality standards and ceremai fruit extract (EBC) has weak category elastase enzyme inhibitory activity.
Edukasi Penggunaan Obat Antidiabetes saat Berpuasa Ramadhan di Panti Asuhan Hasanudin Pandeglang Stiani, Sofi Nurmay; Yusransyah, Yusransyah; Chairani, Farahdina; Adini, Syilvi; Noviyanto, Fajrin; Ernawati, Eneng Elda; US, Sumarlin; Udin, Baha; Pratiwi, Linda Rani
Jurnal Pengabdian Pada Masyarakat Vol 9 No 4 (2024): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v9i4.934

Abstract

Umat muslim diwajibkan untuk berpuasa di bulan Ramadhan, temasuk penderita Diabetes Melitus sehingga terdapat perubahan waktu makan dan menyebabkan terjadinya perubahan pola waktu penggunaan obat yang tidak tepat pada saat berpuasa dan dapat menimbulkan efek yang tidak diinginkan sehingga tidak tercapainya target terapi obat. Kesalahan penggunaan obat diabetes dapat dicegah dengan memberikan edukasi terkait penggunaan obat pada saat berpuasa. Oleh karena itu, pemberian edukasi pada pengabdian masyarakat ini menjadi salah satu rangkaian kegiatan utama dengan tujuan untuk meningkatkan pengetahuan masyarakat terkait penggunaan obat diabetes pada saat berpuasa sehingga dapat meningkatan ketepatan dalam mencapai target terapi. Kegiatan ini menggunakan metode ceramah yang dilanjutkan dengan diskusi tanya jawab. Tolak ukur keberhasilan edukasi ini adalah jawaban kuesioner sebelum dan sesudah pelaksanaan edukasi. Total peserta pada kegiatan ini sebanyak 50 orang dengan mayoritas laki-laki berusia 28-33 tahun. Hasil kegiatan ini menunjukan peningkatan pengetahuan penggunaan obat di bulan Ramadhan tanpa harus membatalkan puasa. Hal tersebut ditunjukkan pada peningkatan persentase peserta dengan kategori baik (10%) dan cukup (2%). Selain itu, hasil uji statistik menunjukkan terdapat perbedaan signifikan antara jawaban benar saat sebelum dan setelah edukas. Hal ini membuktikan bahwa pelaksanaan edukasi sangat penting untuk meningkatkan pengetahuan masyarakat terutama terkait penggunaan obat di bulan Ramadhan. Muslims are required to fast in the month of Ramadan, including people with Diabetes Mellitus so that there are changes in meal times and cause changes in the pattern of inappropriate drug use during fasting and can cause unwanted effects so as not to achieve the target of drug therapy. Errors in the use of diabetes drugs can be prevented by providing education related to the use of drugs during fasting. Therefore, providing education in this community service is one of the main series of activities with the aim of increasing public knowledge related to the use of diabetes drugs during fasting so as to increase accuracy in achieving therapeutic targets. This activity uses a lecture method followed by a question and answer discussion. The benchmark for the success of this education is the answer to the questionnaire before and after the implementation of education. The total number of participants in this activity was 50 people with the majority of men aged 28-33 years. The results of this activity showed an increase in knowledge of the use of drugs in the month of Ramadan without having to break the fast. This is shown in the increase in the percentage of participants in the good (10%) and fair (2%) categories. In addition, the statistical test results showed a significant difference between the correct answers before and after education. This proves that the implementation of education is very important to improve public knowledge, especially regarding the use of drugs in the month of Ramadan.
Perbandingan Aktivitas Antioksidan dan Antikolesterol serta Kandungan Fenolik dan Flavonoid dari Ekstrak Khaya (Khaya anthotheca) Suryani, Nani; Komalasari, Komalasari; Sulistriyani, Sulistriyani; Rudiana, Tarso; Ernawati, Eneng Elda; Indriatmoko, Dimas Danang; Jayantie, Dhyneu Dwi; Khaerunnisa, Arini
Jurnal Kartika Kimia Vol 8 No 1 (2025): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v8i1.906

Abstract

Hypercholesterolemia is closely related to cardiovascular disease, which can increase the risk of atherosclerosis. Oxidative stress is related to the development of atherosclerosis because it is related to cellular responses triggered by an imbalance between oxidants and reductants in various layers of blood vessel tissue. K. anthotheca has pharmacological benefits as an antileishmaniasis and antimalarial. The purpose of this study was to determine the antioxidant and anticholesterol activity of K. anthotheca bark based on the type of solvent and to determine the phenolic and flavonoid content of the most active extract. The results indicated that ethyl acetate extract had the best antioxidant activity compared to n-hexane and ethanol extracts, with an IC50 value of 47.82 ppm, followed by ethanol extract at 48.46 ppm and n-hexane extract at 101.89. The value of antioxidant activity is directly proportional to the anticholesterol activity, where the ethyl acetate extract has an EC50 value of 20.42 ppm, the ethanol extract 445.58 ppm, and the n-hexane extract 1,073 ppm. The ethyl acetate extract has a phenolic content of 229.765 mgGAE/g extract and a flavonoid content of 7.63 mgQE/g.
Peningkatan Pengetahuan Siswa dan Siswi SMA Presiden 2 Tanjung Lesung melalui Pelatihan Pembuatan Sabun Cair Ekstrak Daun Sisik Naga Kartika, Eka Yulli; Oktavia, Swastika; Junaedi, Candra; Indriatmoko, Dimas Danang; Jayantie, Dhyneu Dwi; Ernawati, Eneng Elda; Khaerunnisa, Arini; Suryani, Nani; Nurhayati, Ghina Siti; Siswanti, Dwi Marwati Juli; Novi, Cory; Setiawan, Agus
Jurnal Pengabdian Pada Masyarakat Vol 10 No 2 (2025): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v10i2.1033

Abstract

Sabun terbentuk melalui reaksi antara asam lemak dan basa kuat, dan umumnya digunakan sebagai pembersih untuk menghilangkan kotoran pada kulit. Salah satu jenis sabun yang diminati pada saat ini oleh masyarakat yaitu sabun cair. Hal ini dikarenakan penggunaannya yang lebih praktis dan efisien. SMA Presiden 2 Tanjung Lesung merupakan sekolah umum semi militer yang memiliki 2 bidang ilmu yaitu IPA dan IPS. Kegiatan ini bertujuan untuk memberikan pengetahuan dan keterampilan kepada siswa/i SMA Presiden 2 Tanjung Lesung tentang pengaplikasian ilmu dan tekonologi dalam menghasilkan sabun mandi. Metode kegiatan yang dilakukan berupa pemaparan materi dan pelatihan pembuatan sabun cair dengan campuran ekstrak daun sisik naga (bahan alam) serta memberikan kuisioner berupa pretest dan postest untuk mengetahui pengaruhnya kepada siswa/i. Hasilnya didapatkan bahwa terdapat peningkatan pengetahuan dari kegiatan pengabdian kepada masyarakat (PKM) dari nilai rata-rata prestest 70,23 menjadi 86,28 untuk nilai posttest. Soap is formed through a reaction between fatty acids and a strong base and is commonly used as a cleanser to remove dirt from the skin. One type of soap that is currently popular among the public is liquid soap due to its practical and efficient use. SMA Presiden 2 Tanjung Lesung is a semi-military public school that offers two fields of study: Science and Social Studies. This activity aims to provide knowledge and skills to the students of SMA Presiden 2 Tanjung Lesung on the application of science and technology in producing bath soap. The methods used in this activity include material presentation, hands-on training in making liquid soap with dragon scale leaf extract (a natural ingredient), and pretest and post-test to measure the impact. The results showed an increase in knowledge from this community service activity, with the average pretest score rising from 70.23 to an average post-test score of 86.28.
Edukasi Efek Samping Obat dan Resiko Penggunaan Obat yang Salah di Pantiasuhan Hasanudin Pandeglang Stiani, Sofi Nurmay; Yusransyah, Yusransyah; Ernawati, Eneng Elda; Udin, Baha; US, Sumarlin; Fahlevy, Muhamad Ichsan; Junaedi, Candra; Noviyanto, Fajrin
Jurnal IPTEK Bagi Masyarakat Vol 5 No 1 (2025)
Publisher : Ali Institute of Research and Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55537/j-ibm.v5i1.1117

Abstract

Improper use of drugs can cause adverse side effects, especially among people with limited access to information such as people living in orphanages. This community service activity aims to increase the knowledge of residents of the Hasanudin Pandeglang Orphanage regarding the side effects of drugs and the risks of incorrect drug use through educational activities. The method used is health education accompanied by a question and answer discussion and pretest and posttest evaluation using a knowledge questionnaire. The questionnaire was designed to measure participants' understanding of the material presented before and after education. The number of participants in this activity was 57 participants. The evaluation results showed a significant increase in participants' knowledge scores after the education. This proves that this educational activity is effective in increasing awareness and understanding of the safe use of drugs. This activity is expected to be a model for similar health education in other orphanages to prevent irrational drug use.
Aphrodisiac Effects of Ethanolic Extract from White Ginger Rhizome (Zingiber officinale Rosc. var. officinarum) on Male Wistar Rats Oktavia, Swastika; Ernawati, Eneng Elda; Putra, Anca Suryadi
JST (Jurnal Sains dan Teknologi) Vol. 13 No. 3 (2024): Oktober
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/jstundiksha.v13i3.84670

Abstract

Erectile dysfunction (ED) is a common condition marked by difficulty maintaining a penile erection, often linked to reduced nitric oxide (NO) production. This study investigates the aphrodisiac properties of ethanolic white ginger extract (Z. officinale Rosc. var. officinarum) in male Wistar rats. Sixteen male and sixteen female rats were divided into four groups: two groups received 25% and 50% ginger extract, one served as a negative control, and the other as a positive control using sildenafil. Ginger rhizomes were dried, powdered, and extracted with ethanol. Phytochemical analysis revealed alkaloids, flavonoids, tannins, saponins, and terpenoids. Behavioral parameters, including introduction (approach to females), climbing, and coitus, were observed to evaluate sexual activity. The group treated with 50% ginger extract showed the highest frequency of introduction and climbing, while the sildenafil group exhibited the highest coitus frequency. Statistical analysis using the Kruskal-Wallis test indicated significant differences in sexual behavior across the groups. The study suggests that white ginger extract, especially at higher concentrations, may have aphrodisiac effects by enhancing sexual behavior in male rats. This could be due to its bioactive compounds affecting hormone levels or the nervous system. The findings propose white ginger as a potential natural treatment for ED, with further research required to explore its implications in humans.
SERUM ANTIAGING KOMBINASI EKSTRAK BUAH CEREMAI (Phyllanthus acidus L. SKEELS) DAN KULIT BUAH SEMANGKA (Citrullus lanatus THUNB.) Ernawati, Eneng Elda; Suryani, Nani; Nuramalia, Sifa; Rudiana, Tarso
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1530

Abstract

Kulit dapat mengalami penuaan atau aging yang didefinisikan sebagai hilangnya keseimbangan homeostatik suatu organisme secara progresif. Indikator aging diantaranya keberadaan hyperpigmentasi yang disebabkan oleh enzim tyrosinase. Banyak Cara yang dapat dilakukan untuk  mencegah aging adalah dengan melakukan perawatan kulit menggunakan serum antiaging. Senyawa bioaktif dari tanaman berkembang dan populer untuk digunakan sebagai bahan kosmetik dalam formulasi karena banyak dilaporkan mengandung vitamin, antioksidan, minyak essensial, protein, senyawa fenolik, dan zat aktif lainnya. Buah Ceremai (Phyllantus acidus) diidentifikasi mengandung senyawa asam glikolat dan asam sitrat, sedangkan kulit buah semangka (Citrullus lanatus) mengandung saponin, tanin, alkaloid dan flavonoid. Tujuan penelitian ini adalah untuk membuat formulasi serum  antiaging  dari kombinasi buah ceremai (Phyllantus acidus) dan ekstrak kulit buah semangka (Citrullus lanatus) sebagai inhibisi enzim tirosinase. Penelitian ini  meliputi pengujian aktivitas ekstrak dan sediaan serum terhadap inhibisi enzim tirosinase dengan metode in vitro menggunakan ELISA. Hasil penelitian aktivitas inhibisi enzim tirosinase ekstrak buah ceremai menunjukan nilai IC50 sebesar 9.551 µg/mL dan ekstrak kulit buah semangka 3.304 µg/mL. Inhibisi enzim tirosinase serum F1 mendapatkan nilai IC50  1.137 µg/mL sedangkan F2 sebesar 1.025 µg/mL.  Hasil yang dapat disimpulkan bahwa ekstrak kulit buah semangka lebih aktif sebagai inhibisi enzim tirosinase daripada ekstrak buah ceremai tetapi hasil sediaan serum menunjukan hasil yang memiliki potensi sebagai inhibisi enzim tyrosinase.
Telepharmacy Education As A Step To Strengthen The National Health System In Pandeglang Regency: Edukasi Telefarmasi Kepada Masyarakat Kabupaten Pandeglang Sebagai Langkah Memperkuat Sistem Kesehatan Nasional Yusransyah, Yusransyah; Stiani, Sofi Nurmay; Ismiyati, Renditya; Udin, Baha; Pratiwi, Linda Rani; Maharani, Sylvianti; US, Sumarlin; Ernawati, Eneng Elda
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2024): Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31849/dinamisia.v8i2.18816

Abstract

A health sector that uses information and communication technology (ICT) can offer a new perspective on health service delivery and help overcome the problem of insufficient availability of health workers. The form of implementation can be telepharmacy services, but only a few people understand telepharmacy. This service aims to provide telepharmacy education to the people of Pandeglang Regency as a first step to strengthening the National Health System. Health education is delivered through visualization using the community relations method. As part of the Community Service program, this activity aims to provide telepharmacy education to the people of Pandeglang Regency, which is part of improving the National Health System.
Co-Authors Adini, Syilvi Agus Setiawan Anisah Arini Khaerunnisa Baha Udin Chairani, Farahdina Cory Novi Fahlevy, Muhamad Ichsan Fajrin Noviyanto, Fajrin Indriatmoko, Dimas Danang Ismiyati, Renditya Jayantie, Dhyneu Dwi Junaedi, Candra Kartika, Eka Yulli Komalasari Komalasari Maharani, Sylvianti Nani Suryani Nuramalia, Sifa Nurhayati, Ghina Siti Pratiwi, Linda Rani Putra, Anca Suryadi Siswanti, Dwi Marwati Juli Stiani, Sofi Nurmay Sulistriyani, Sulistriyani Swastika Oktavia Tarso Rudiana, Tarso US, Sumarlin Yusransyah, Yusransyah Yustika, Rd. Widya