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All Journal Jurnal Insan Farmasi Indonesia Tri Dharma Mandiri: Diseminasi dan Hilirisasi Riset Kepada Masyarakat (Jurnal Pengabdian Kepada Masyarakat) Journal of Pharmacy Science and Technology
Yuli Ainun Najih
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Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health Social Sciences

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PENGARUH SURFAKTAN PEG-7 GLYCERYL COCOATE-SPAN80 DAN PEG-40 HYDROGENATED CASTOR OIL-SPAN80 TERHADAP KARAKTERISTIK FISIK KRIM alfa-ARBUTIN Yuli Ainun Najih; Yuyun Nailufa; Dita Nurlita Rakhma; Nur Hardianti Ruchmana
Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i1.624

Abstract

?-arbutin is a derivative of hydroquinone to treat hyperpigmentation disorders which acts as a tyrosinase inhibitor. The hydrophilic nature of ?-arbutin requires a dosage form that can increase its penetration into the skin is a cream. The purpose of this study was to determine the effect of surfactants PEG-7 Glyceryl Cocoate-Span80 and PEG-40 Hydrogenated Castor Oil-Span80 on the physical characteristics of ?-arbutin cream. The cream formulation made into 2 formula, F1 using PEG-40 Hydrogenated Castor Oil-Span80 and F2 using PEG-7 Glyceryl Cocoate-Span80. Physical characteristics including organoleptic testing, emulsion type, pH, viscosity and Spreadability. The results obtained from the two cream formulas showed a significant difference in the measurement of pH, viscosity and Spreadability values. The results of the pH value of F1 and F2 are 5.74 and 6.24. The viscosity results obtained from F1 and F2 are 50500cPs and 43333cPs. The spreadability measurement results obtained from F1 and F2 were 9.93cm and 11.33cm. The results spreadability will be inversely proportional to the results of the viscosity obtained. The higher the viscosity yield, the smaller the spreadability of a cream.
PEMBENTUKAN KOKRISTAL KETOKONAZOL-ASAM SUKSINAT YANG DIBUAT DENGAN METODE PENGGILINGAN (GRINDING) Yuli Ainun Najih; Dwi Setyawan; Achmad Radjaram
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Voume 1 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v1i1.30

Abstract

The Co-crsytal formation ketoconazole (KTZ) - succinic acid (SA) has been performed by molar ratio (1:1) using milling method (grinding).. Milling is done using Planetary Ball mill PM 200 MA-type tool, Retsch with 75 rpm milling speed. The physical mixture of KTZ and AS molar ratio (1:1) was prepared in the absence of a dry grinding solution with milling time of 5, 15, 30, 45 and 60 min at a constant velocity. The milling results are seen by using powder X-ray diffraction (PXRD) at an angle (2θ = 7.8o). From the results of X-ray powder diffraction there is an increase in the percentage of crystalline (% w/w). The result of the grinding time curve with the percentage of crystal (%w/w), the result that the percentage of crystalline (% w/w) increases linearly with increasing milling time (min) based on the maximum intensity data of each milling time by the line equation (y = 0.690x + 51.09) and correlation coefficient r = 0.9905. As conclusion, based on kinetic formation of cocristal with milling method obtained for slope value = 0,690 % cocrystall (%b/b)/min.
Edukasi Kesehatan Terkait Pencegahan dan Penanganan Hiperurisemia di Kelurahan Keputih Kota Surabaya Nugraha Putra, Oki; Pramudita Riwanti; Yuli Ainun Najih; Intan Kris Prasetyanti; Angelica Kresnamurti; Nurul Damayanti; Ayunanda Risetyaningsih; Sylvia Rizki Ramadhani; Tembayatul Muhibah; Nindya Maskurisna Hamami; Fatimah Noor Azizah Vannia Zahra
TRI DHARMA MANDIRI: Dissemination and Downstreaming of Research to the Community (Journal of Community Engagement) Vol 4 No 2 (2024)
Publisher : SMONAGENES Research Center, Univeritas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtridharma.2024.004.02.102

Abstract

Hyperuricemia is a disease characterized by increased uric acid levels in the blood. Hyperuricemia is significantly associated with the incidence of gouty arthritis which can interfere with the patient's physical activity. Hyperuricemia can be prevented with a healthy lifestyle. This community service activity aims to provide health education regarding the prevention and treatment of hyperuricemia. The method of implementing this activity is counseling several residents at the RW hall in Keputih Subdistrict, Surabaya. Counseling is carried out in the form of presentations or lectures accompanied by leaflets followed by discussions and questions and answers. Participants were asked to fill out a questionnaire before and after the education to measure their level of knowledge regarding the prevention and treatment of hyperuricemia. The material provided in this counseling is normal uric acid values in men and women, risk factors for hyperuricemia, symptoms of hyperuricemia, efforts to prevent hyperuricemia, and ways to deal with hyperuricemia if hyperuricemia occurs. This counseling was attended by 55 participants, but only 32 participants filled in the questionnaire completely. The mean knowledge score of participants increased significantly from 11.31±1.59 before counseling to 12.09±0.85 after counseling (p-value = 0.018). This shows that counseling using presentations accompanied by the provision of leaflets can increase participants' knowledge. Regular follow-up outreach activities are needed to educate the public regarding the prevention and treatment of hyperuricemia.
Co-Authors Achmad Radjaram Ayunanda Risetyaningsih Dwi Setyawan Fatimah Noor Azizah Vannia Zahra Intan Kris Prasetyanti Kresnamurti, Angelica Nailufa, Yuyun Nindya Maskurisna Hamami Nugraha Putra, Oki Nur Hardianti Ruchmana Nurul Damayanti Pramudita Riwanti Rakhma, Dita Nurlita Sylvia Rizki Ramadhani Tembayatul Muhibah