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All Journal Jurnal Surya Medika PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Ilmiah Pharmacy Jurnal Farmasi dan Sains Indonesia (JFSI) JUKESHUM: Jurnal Pengabdian Masyarakat Lentera Negeri Sinteza Jurnal Teknologi Informasi untuk Masyarakat (Jurnal Teknokrat)
Arief Rafsanjani
Universitas Hamzanwadi
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Lumbung Farmasi : Jurnal Ilmu Kefarmasian

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Efektivitas Ekstrak Etanol Daun Ciplukan (Physalis angulata L.) Terhadap Penurunan Kadar Trigliserida Pada Mencit (Mus musculus) Rafsanjani, Arief; Salsabila, Aulia; Yuliana, Tri Puspita
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 2 (2025): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i2.27605

Abstract

Hypertriglyceridemia is a condition when triglyceride levels in the blood increase. High triglyceride levels can cause atherosclerosis, which is a risk factor for cardiovascular disease. The ciplukan plant contains chemical compounds, namely flavonoid compounds. Flavonoid compounds can reduce triglyceride levels by increasing the activity of the lipoprotein lipase enzyme. This research aims to determine the potential of Ciplukan (Physalis angulata L) leaf extract in reducing triglyceride levels in mice (Mus musculus). This type of research is experimental research with a Pretest-Posttest Control Group design. This study consisted of a negative control group, positive control, treatment dose I (2.8 mg/20 gr BW), dose II (5.6 mg/20 gr BW), and dose III (8.4 mg/20 gr BW ). Based on the results of the pne-way ANOVA analysis test, it showed significant differences between the negative control group and the positive control group, treatment dose I, dose II, and dose III with a significance value of p<0.05. The conclusion of this research is that the ethanol extract of ciplukan leaves has the potential to reduce triglyceride levels in mice induced by quail egg yolk.
Co-Authors Aditya Noviadi Rakhmatullah Ardyati, Sulistia Baiq Risma Fatmayanti Endang Darmawan Erma Ewisa Oktresia Ersi Arviana Ihsan Fitriwati Sovia Hamdi, Muhammad Irsyadul Hamidah, Laeli Aminatul Hardiyanti, Novi Jeli Marlita Khairurrizki, Amanda Leny Ramadhan Muhlisun Azim Novi Hardiyanti Noviatsyani, Nisrina Nurcholid Umam Kurniawan Puspawan Hariadi Salsabila, Aulia Sasmita, Yulinda Dinar Sulistia Ardyati Tri Puspita Yuliana Wati, Ambar Yuyun Febriani