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All Journal PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kesmas Asclepius Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Abdimas Bina Bangsa Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Sinteza Journal of Pharmaceutical and Sciences. Lentera Negeri JPEPT
Fitriwati Sovia
Hamzanwadi University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Combination of Traditional Medicine and Synthesis Medicine Therapy for Hypertension and Diabetic Patients Ersi Arviana Ihsan; Fitriwati Sovia; Erma Ewisa Oktresia; Tri Puspita Yuliana; Sulistia Ardyati; Arief Rafsanjani
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 18 No. 01 Juli 2021
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v18i1.9348

Abstract

Hypertension and diabetic are interrelated diseases affect atherosclerosis. This study aims to analyze the combination of traditional medicines and synthetic medicine with a job background for patients with hypertension and diabetic. Case-control study method retrieves patient data with medical records. Sampling was done with a purposive sampling technique of 30 respondents conducted in March-June at Labuhan Lombok Health Center. The results showed the percentage of diabetic patients was 26.67% for men and 73.33% for women with a background of 60% of traders, 20% of farmers, 13.3% of fishermen, and housewives of 6.7%. Furthermore, for hypertension patients, the percentage was 13.33% for men and 86.67% for women with a background of 40% of traders, 53.3% for farmers, 6.7% for fishermen. For traditional medicine used are Moringa oleifera L., Cucumis sativus L., jamu gendong, Averrhoa bilimbi L., Curcuma longa L., and Artocarpus camansi Blanco. Based on this, the risk factors for women are more generous than for men, and the use of a combination of drugs gives positive results in improving health.
Peran Kader Posyandu terhadap Tingkat Kunjungan Masyarakat Hartini Haritani; Puspawan Hariadi; Ewisa Oktresia; Fitriwati Sovia; Baiq Maylinda Gemantari
Jurnal Kesmas Asclepius Vol 4 No 2 (2022): Jurnal Kesmas Asclepius
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/jka.v4i2.4456

Abstract

This study aims to describe the role of posyandu cadres on the level of visits by the users. The method used in this study is descriptive qualitative with a program evaluation approach. The results obtained from this study are that the number of visits by pregnant women, toddlers, and the elderly has increased. However, a strategy is needed to increase the interest of young women to utilize posyandu so that they can increase the number of visits by adolescents. In conclusion, the role of Posyandu cadres dramatically contributes to the health needs of small communities, especially in villages. Keywords: Cadres, Posyandu, Healthy
DETERMINASI KEPATUHAN MINUM OBAT PADA PASIEN DIABETES MELLITUS TIPE II DI PUSKESMAS TERARA: ANALISIS KORELASI FAKTOR-FAKTOR PENGARUH Sovia, Fitriwati; Anjani, Rizky Puji; Ramadhan, Leny
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 2 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.2115

Abstract

Diabetes mellitus is a chronic disease that requires ongoing management because it cannot be permanently cured. Adherence to the treatment plan is crucial to prevent deterioration in physical condition. This study aims to analyze the correlation between factors affecting medication adherence in patients with type II diabetes mellitus at Terara Community Health Center. This research uses an observational analytic design with a cross-sectional approach. The study population consists of 151 patients with type II diabetes mellitus, with a sample of 35 individuals selected through purposive sampling. Data were collected using a questionnaire and analyzed with Fisher's test. The results indicate that factors such as gender (P=0.015), occupation (P=0.015), knowledge (P=0.006), attitude (P=0.001), motivation (P=0.021), and family support (P=0.004) have a significant correlation with medication adherence. Conversely, age, education, and healthcare support did not show a significant correlation with medication adherence. In conclusion, factors such as gender, occupation, knowledge, attitude, motivation, and family support significantly influence medication adherence in patients with type II diabetes mellitus at Terara Community Health Center.
PENINGKATAN PENGETAHUAN MASYARAKAT MELALUI EDUKASI: PATUHI, OBATI DAN KENDALIKAN DIABETES Hariadi, Puspawan; Oktresia, Erma Ewisa; Sovia, Fitriwati; Gemantari, Baiq Maylinda
Jurnal Abdimas Bina Bangsa Vol. 6 No. 1 (2025): Jurnal Abdimas Bina Bangsa
Publisher : LPPM Universitas Bina Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46306/jabb.v6i1.1703

Abstract

Diabetes Mellitus (DM) can lead to various complications, both macrovascular and microvascular. Diabetes education interventions play a crucial role in DM management, as they help improve patients' knowledge and adherence to diabetes management strategies. This study involved three sessions: a pre-test, an educational session, and a post-test. Among 53 respondents, the proportion of participants with a high level of knowledge increased from 30 (56.6%) to 43 (81.1%). Meanwhile, those with a low level of knowledge decreased from 10 (18.9%) to 1 (1.9%). This increase in knowledge levels demonstrates the effectiveness of the education provided. The average pre-test knowledge score was 69.06, compared to a post-test score of 86.23, demonstrating a significant improvement. Wilcoxon test analysis showed a significance value of <0.05. Thus, the "Patuhi, Obati dan Kendalikan Diabetes" education program for participants of the Chronic Disease Management Program (Prolanis) significantly enhanced participants' knowledge levels.
Identifikasi Interaksi Obat Pada Pasien Lansia Yang Berisiko Sindrom Metabolik Di Puskesmas Aikmel Sovia, Fitriwati; Hardiyanti, Novi; Rafsanjani, Arief; Oktresia, Erma Ewisa
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p39-46

Abstract

Metabolic syndrome is an increasingly prevalent health problem in both developed and developing countries, including Indonesia. The treatment of metabolic syndrome often involves polypharmacy, which increases the potential for drug interactions. Drug interactions are considered clinically important if they can cause increased toxicity or reduce the therapeutic effects of drugs, leading to a failure to achieve the desired therapeutic effect. Reported cases of drug interactions are more common in elderly patients. This study aims to determine the potential Drug-drug Interactions (DDIs) in elderly patients at risk of metabolic syndrome at Puskesmas Aikmel. The study uses a descriptive observational method with prospective data collection. The population in this study consists of outpatient patients at Puskesmas Aikmel from May to July 2021, meeting the inclusion criteria: patients diagnosed at risk of metabolic syndrome, elderly patients (age ? 60 years), and using a minimum of 2 drugs. Sampling was done using total sampling technique. The results of the study indicate 99 cases of potential drug interactions identified in the prescription of elderly patients. The drug classes with potential interactions include antihypertensive drugs in 51 (51.51%) cases, antihyperglycemic drugs in 42 (42.42%) cases, and dyslipidemia drugs in 6 (6.06%) cases. The types of drug interactions observed were pharmacokinetic interactions in 37 (37.37%) cases, pharmacodynamic interactions in 58 (58.58%) cases, and unknown interactions in 4 (4.04%) cases. The severity of these potential interactions was classified as minor in 5 (5.05%) cases, moderate in 86 (86.87%) cases, and major in 8 (8.08%) cases.
Uji Efektivitas Ekstrak Daun Renggak (Amomum dealbatum Roxb.) Sebagai Antihiperurisemia Pada Mencit Sovia, Fitriwati; Al-Adawiyah , Rosita; Yuliana , Tri Puspita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.747

Abstract

Background: Hyperuricemia, resulting from excessive uric acid levels, can trigger chronic inflammation and increase the risk of gout. Conventional therapies such as allopurinol are associated with adverse effects, highlighting the need for natural alternatives. Renggak leaves (Amomum dealbatum Roxb.), an endemic plant from Lombok rich in flavonoids, have potential as xanthine oxidase inhibitors but remain underexplored. Objective: To evaluate the antihyperuricemic effect of renggak leaf extract in male white mice, determine the optimal dosage, and compare its efficacy with allopurinol. Methods: This study employed a pretest-posttest control group design. Hyperuricemia was induced using chicken liver juice administered for 14 days. The animals were divided into five groups: negative control (1% CMC-Na), positive control (allopurinol 10 mg/kg BW), and three extract-treated groups (50, 250, and 500 mg/kg BW), which received the extract for 21 days. Results: All extract doses significantly reduced uric acid levels (P < 0.05). The 500 mg/kg BW dose was the most effective (44.54% reduction), showing no significant difference compared to allopurinol (48.52%; p = 0.490). The effect is presumed to occur through xanthine oxidase inhibition by flavonoids. Conclusion: Renggak leaf extract, particularly at a dose of 500 mg/kgBW, shows potential as an alternative therapy for hyperuricemia with efficacy comparable to allopurinol. However, further studies such as toxicity tests, pharmacokinetic evaluations, and clinical trials are needed to validate its broader application.
Tingkat kunjungan masyarakat pada pelayanan posyandu keluarga di desa Toya, Nusa Tenggara Timur Hartini Haritani; Sulistia Ardyati; Erma Ewisa Oktresia; Fitriwati Sovia; Muhammad Zainul Majdi; Atiaturrahmaniah Atiaturrahmaniah; Baiq Aryani Novianti
Lentera Negeri Vol. 3 No. 1 (2022): Lentera Negeri
Publisher : Indonesian Institute For Counseling, Education and Therapy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29210/99360

Abstract

Posyandu cadres are the driving force for the implementation of family posyandu services, both in moving targets, services and reporting. With the changing level of posyandu to a family type of this system increases the workload of posyandu cadres, the competence and skills of cadres need to be improved through training and mentoring. The data obtained was qualitative data with descriptive analysis method.  Data collection was carried out by conducting observations, interviews and technical training to posyandu cadres with the aim of providing knowledge about family posyandu services, and basic skills at tables 1 to table 8 for cadres so that the presence of this small group of people could increase the number of targeted visits to posyandu.  The results obtained from this activity were: the number of visits by pregnant women, toddlers and the elderly had increased. However, the strategy was needed to increase youth's interest in posyandu according to the number of visits by teenagers.
Formulation and Evaluation of the Physical Properties of Clay Mask Containing Ethanol Extract of Kenikir (Cosmos caudatus) Leaves Puspawan Hariadi; Rina Sri Apriani; Baiq Maylinda Gemantari; Tri Puspita Yuliana; Erma Ewisa Oktresia; Fitriwati Sovia
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 1 No. 2 (2025): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v1i2.19

Abstract

The demand for natural-based cosmetic products continues to increase due to their perceived safety and minimal side effects. Kenikir leaves (Cosmos caudatus Kunth) are known to contain active compounds such as flavonoids, tannins, and phenols, which have antioxidant potential and can be utilized in facial mask preparations. This study aims to formulate a clay mask preparation from the ethanol extract of kenikir leaves and evaluate its physical properties. The extract was obtained through maceration using 96% ethanol, and then formulated into three concentrations: F1 (0.5%), F2 (1%), and F3 (2%). The evaluation of the preparation included organoleptic tests, adhesion test, spreadability test, and pH measurement. The results showed that F1 had a pH of 6, adhesion time of 2 seconds, and spreadability of 5.3 cm. F2 had a pH of 6, adhesion time of 2 seconds, and spreadability of 5.2 cm. F3 had a pH of 6, adhesion time of 4.6 seconds, and spreadability of 5 cm. The evaluation results indicated that all clay mask formulations met the physical quality criteria for clay masks.
POTENSI FRAKSI ETIL ASETAT KULIT BUAH RENGGAK (AMOMUN DEALBATUM ROXB) SEBAGAI AGEN ANTIBAKTERI Puspawan Hariadi; Widia Hidayati; Tri Puspita Yuliana; Baiq Maylinda Gemantari; Erma Ewisa Oktresia; Fitriwati Sovia
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 2 No. 2 (2026): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v2i2.1

Abstract

Tanaman renggak (Amomun dealbatum Roxb) merupakan tanaman yang tergolong  dalam jenis tumbuhan aromatik yang termasuk dalam suku jahe – jahean, tanaman ini mengandung senyawa metabolit sekunder berupa flavonoid, Tanin, Alkoloid, Saponin, Steroid yang memiliki potensi sebagai antibakteri. Penelitian ini bertujuan untuk mengkaji potensi fraksi kulit buah dari tanaman renggak sebagai antibakteri dengan variasi konsentrasi 10%, 20%, 30%, 40% terhadap bakteri staphylococcus aureus dan pseudomonas aeruginosa. Fraksinasi dilakukan menggunakan metode fraksi cair – cair, dan pengujian aktivitas antibakteri dilakukan menggunakan difusi sumuran. Hasil pengujian fraksi pada bakteri staphyloccoccus aureus pada konsentrasi 10%, 20%, 30% dan 40 % masing masing memilik daya hambat sebesar 11,45 mm, 12,19 mm, 13,62 mm, 15,38 mm dan pada bakteri peudomonas aeruginosa masing masing sebersar 8,24 mm, 9,23 mm, 11,16 mm, 12,63 mm, hal ini menunjukan bahwa tanaman renggak memiliki potensi sebagai antibakteri.
Efektivitas Infusa Daun Jarak Kepyar (Ricinus communis L.) terhadap Kadar Kolesterol Total dan HDL Serum Darah Tikus Galur Wistar Rani Anggraini Hikmah; Puspawan Hariadi; Fitriwati Sovia
Sinteza Vol. 2 No. 1 (2022): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.569 KB) | DOI: 10.29408/sinteza.v2i1.4367

Abstract

Jarak  kepyar (Ricinus communis L.) adalah salah satu tanaman herbal yang mengandung flavonoid khususnya kuersetin, tanin, dan saponin dimana senyawa-senyawa ini dipercaya dapat memberikan efek antihiperlipidemia. Tujuan dari penelitian ini untuk mengetahui efektivitas infusa dan untuk mendapatkan konsentrasi infusa daun jarak kepyar yang paling efektif sebagai antihiperlipidemia pada tikus galur wistar. Penelitian ini merupakan jenis penelitian true exsperimental dengan rancangan pretest-postest kelompok. Hewan uji terbagi menjadi 5 kelompok yaitu kontrol positif (simvastatin), kontrol negatif dan perlakuan (infusa daun jarak kepyar) dengan konsentrasi 10%, 20% dan 30%  dengan masing-masing kelompok sebanyak 5 ekor. Sebelum perlakuan hewan uji diberikan induksi kuning telur selama 25 hari kemudian diukur kadar kolesterol total, trigliserida, dan HDL. Pengukuran dilakukan sebelum dan sesudah induksi kuning telur kemudian dilakukan kembali setelah infusa daun jarak kepyar diberikan. Parameter yang diukur adalah kadar kolesterol total, trigliserida dan HDL. Berdasarkan hasil pengukuran kadar setelah pemberian infusa daun jarak kepyar diperoleh hasil persentasi penurunan kolesterol total yaitu kontrol negatif (8.43%), kontrol positif (15.28%), konsentrasi 10% (10.23%), konsentrasi 20% (20.03%), dan kelompok konsentrasi 30% (27.13%) dan peningkatan  HDL yaitu kelompok kontrol negatif (1.23%), kontrol positif (9.23%), konsentrasi 10% (2.96%), konsentrasi 20% (7.85%), dan kelompok konsentrasi 30% (5.14%).  Konsentrasi 20% dan 30% memberikan penururunan kadar kolesterol total secara signifikan (p<0.05)  dan peningkatan kadar HDL secara signifikan (p<0.05) oleh kontrol 20% jika dibandingkan dengan kontrol negatif. Infusa daun jarak kepyar (Ricinus communis L.) konsentrasi 30% paling efektif menurunkan kadar kolesterol total dan trigliserida, sedangkan yang paling efektif untuk meningkatkan kadar HDL  adalah konsentrasi 20%.
Co-Authors Al-Adawiyah , Rosita Anjani, Rizky Puji Arief Rafsanjani Atiaturrahmaniah Atiaturrahmaniah Baiq Aryani Novianti Baiq Maylinda Gemantari Erma Ewisa Oktresia Ersi Arviana Ihsan Ewisa Oktresia Hardiyanti, Novi Hartini Haritani Lalu Khilal Ramadani Leny Ramadhan M. Herry Hartono Muhammad Zainul Majdi Novi Hardiyanti Puspawan Hariadi Putri Ayu Rizqi Rani Anggraini Hikmah Rina Sri Apriani Sulistia Ardyati Sulistia Ardyati Tri Puspita Yuliana Widia Hidayati Yuliana , Tri Puspita