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All Journal Pharmaciana: Jurnal Kefarmasian As-syifaa Jurnal Farmasi Journal of Pharmaceutical and Health Research Nusantara Hasana Journal JUMANTIK (Scientific Journal of Health research) Pharmaceutical Reports JURNAL PENGABDIAN MASYARAKAT YAMASI Advances in Healthcare Research Jurnal Ragam Pengabdian

Nurlina Nurlina

Faculty Of Pharmacy, Universitas Muslim Indonesia, Makassar

Author-ID : 2644984

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN LOSIO EKSTRAK METANOL ALGA HIJAU Caulerpa racemosa Nurlina Nurlina; M Ilham Tomagola; Riskawati Angraini
As-Syifaa Jurnal Farmasi Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Caulerpa racemosa is one type of green algae has the ability to defend against radiation of ultraviolet. Lotion is a liquid or semi-liquid preparation containing one or more active ingredients with a suitable vehicle and provides a comfortable and good feel to the skin. The aim of this research was to obtain the optimum formula based on organoleptic testing, viscosity, pH, flow type, globule of dispersion, and antioxidant activity. The method of this research is experimentally which done by making some design of lotion formulation from methanolic extract of green alga Caulerpa rasemosa. Stability of losio was evaluated include organoleptic testing, pH measurement, type of emulsion, viscosity, flow type, size and distribution of dispersion globule. Determining of effectiveness of lotion as an antioxidant by IC50 value with UV-Vis spectrophotometry method. Results of this research collected and processed statistically with the Completely Randomized Design method, then made the discussion and taken the conclusion. Based on the evaluation, it was found that Losio containing 0.75% methanolic extract of Caulerpa racemosa green algae (Formula III) had the most optimum pharmaceutical stability. And the three losio formulas containing methanol extract of Caulerpa racemosa green algae have antioxidant activity.

FORMULASI SABUN CAIR PENCUCI TANGAN YANG MENGANDUNG EKSTRAK DAUN KEMANGI (Occimum basilicum L.) Nurlina Nurlina; Faisal Attamimi; Rosvina Rosvina; M. Ilham Tomagola
As-Syifaa Jurnal Farmasi Vol 5, No 2 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

A study about formulation Handwash liquid soap which contain etanol extract of occimum folium (Ocimum basilicum L.). Has been conducted. This study aims to product the stable formulation of handwash liquid soap which contain etanol extract of occimum folium (Ocimum basilicum L.).This study was conducted using three variations of viscosity agent. Then do some test with storage method with organoleptic parameters, pH, foaming test, viscosity and type of flow, before and after imposed conditions.Organoleptic test result showed theres no change at II and III, test showed that is stable because still at soap pH before and after imposed condition. Statistical analysis of viscosity test showed there is difference for each formula before and after storage condition. Yield value showed difference yield value before and after strorage condition and at formula there no difference. At rheogram curve theres coincides at formula III before and after imposed condition. For foaming test , three formula is stable because theres have a good foam. The conclusion is the stable handwash liquid soap is formula III. Key words : Formulation, Handwash Liquid Soap, Occimum folium

Kandungan flavanoid total dan aktivitas antimikroba serbuk biji kakao (Theobroma cacao) asal kabupaten enrekang Sulawesi Selatan Andi Emelda; Rusli Rusli; Nurlina Nurlina; Irma Santi
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Cocoa and its derivatives are rich in flavonoids. Flavonoid content of cocoa beans is affected by the treatment process. The aim of this study are to determine total flavonoids and antimicrobial activity of cocoa powder. This study used unfermented cocoa beans in the form of powder. Testing of the total flavonoids was conducted using an aluminum chloride colorimetric assay. The minimum inhibitory concentration (MIC), Minimum Bactericidal Concentration (MBC), and antimicrobial activity of cocoa bean powder were tested by using ten bacteria: Staphylococcus epidermidis, Bacillus subtilis, Escherichia coli, Salmonella thypi, Shigella dysentriae, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus mutans, Vibrio cholerae, and Propioni bacterium agne. The result of measurement of the total flavonoid of unfermented cocoa powder is 22.62 mg EC/g. The screening of antimicrobial with concentration of 0.1% of cocoa powder gives inhibition in Streptococcus mutans, dysentriae Shigella, Escherichia coli, Vibrio cholerae bacterium and Propioni bacterium agne, while at a concentration of 0.5% gives inhibition at all test bacteria. In the antimicrobial activity test using a concentration of 0.5%, 1%, 2% and 4%, the highest resistance zone is shown at a concentration of 4 %. The results show that the diameter zone of inhibition for the bacteria Shigella dysentriae is 11.33 mm. The 10 mm of diameter zone of inhibition are indicated by streptococcus mutans, Escherichia coli, Propioni bacterium agne, Staphylococcus aureus and Bacillus subtilis while 11 mm zone of inhibition demonstrated by Salmonella thypi and Staphylococcus epidermidis. The number of the diameter zone of inhibition, 12 mm, was shown in Pseudomonas aeruginosa. In conclusion, the powder of unfermented cocoa beans provides flavonoids 22,62 mg EK/g and have the antimicrobial activity.

PROFIL PENYIMPANAN OBAT DI PUSKESMAS TAMALANREA JAYA KOTA MAKASSAR Nurlina Nurlina; Bayu Putra; Arnilasari Arnilasari
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.787

Storage of pharmaceutical dosage forms and single-use medical devices is a regulation of the pharmaceutical dosage forms received to be safe (not to lost), to avoid physical and chemical damage and the quality remains guaranteed, in accordance with the requirements set. This research aimed to find out the profile of drug storage in Tamalanrea Jaya subdistrict community Health Center in Makassar City. This research was a descriptive study. The informant in this study was the Head of Pharmaceutical Installation of Tamalanrea Jaya Makassar Health Center. Data was collected through in-depth interviews and observations. The results of the study stated that infrastructure facilities meeting the prevailing regulation in drug storage warehouses according to conformity percentage were 81%. The organisation of drugs in the storage warehouse of community Health Center Pharmaceutical Installation by 85% was carried out based on the standards. The card stock of the drug was fulfilled, which the percentage of conformity indicated 100%.

Evaluasi Profil Penyimpanan Obat Di Rumah Sakit Islam Faisal Kota Makassar Terhadap Pelayanan Kefarmasian Nurlina Nurlina; Andi Maulana Kamri; Andi Nadilla Arfah
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 7, No 4 (2022)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/jumantik.v7i4.12638

Drug storage is a method of maintaining pharmaceutical supplies aimed at maintaining the quality of a drug. Improper storage of drugs can cause drug damage, be ineffective in treatment, and will be a loss to the hospital. The purpose of this study was to determine the profile of drug storage in the Pharmacy Installation of Faisal Islamic Hospital, Makassar City. This research is a descriptive qualitative research in which the data is obtained from in-depth interviews, direct observation, document review, and checking of the condition of drug stability in the Pharmacy Installation. The results showed that the facilities and infrastructure only reached 81% compliance, were some shortcomings such as moldy walls and no double doors. Preparation of drugs in the storage warehouse of the Pharmacy Installation of the Faisal Islamic Hospital reached 100% carried out according to applicable standards. The recording of the card stock has been carried out well with a conformity percentage of 100%. Checking the condition of drugs such as color, odor, shape, clarity, and packaging is done properly every day, checking expiration every month. This study concludes that facilities and infrastructure are one of the supports to improve pharmaceutical services in hospitals in terms of storage.

The Neutralizing Effect of Squeezed Juice, Infusion and Ethanol Extract of Miana Leaves Isnayanti Isnayanti; Ira Asmaliani; Nurlina Nurlina; Mirawati Mirawati
Pharmaceutical Reports Vol 2, No 1 (2023): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharm rep.v2i1.230

The traditional use of miana leaves as a remedy for various ailments, including stomach acid, is well-documented. The utilization of traditional treatments is prevalent due to the absence of side effects associated with synthetic chemical treatments. The consumption of miana leaves by communities is typically achieved through the ingestion of the juice extracted from fresh leaves or by boiling the leaves in water. The purpose of this study is to investigate the mechanism of action of miana leaves as a stomach acid remedy, specifically, its neutralizing effect on stomach acid. The study was conducted on water extracts using squeezed juice and infusion methods, as well as ethanol extracts using the maceration method. The dosage used was obtained by converting the commonly used dosage by the community, which is 3 medium-sized leaves. The average weight of 1 fresh leaf is 1g and the volume of medicine consumed is 1 tablespoon or 15 mL. The concentration for squeezed juice is 20%, infusion 2.08% and ethanol extract 0.28%. The results obtained from maceration, infusion, and miana leaf extract demonstrate a neutralization capacity of 26.617 ± 0.236; 26.7 ± 0.05 and 26.633 ± 0.07 respectively. In conclusion, this study demonstrates that miana leaves possess a neutralizing effect on stomach acid, and may be used as a remedy for stomach acid.

Formulasi dan Uji Aktivitas Sediaan Hair Tonic Kafein untuk Menstimulasi Pertumbuhan Rambut pada Hewan Uji Marmut Aztriana Aztriana; Nurlina Nurlina; Dian Safitri Achmad; Vina Purnamasari; A Hasrawati
Journal of Pharmaceutical and Health Research Vol 4 No 2 (2023): June 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i2.3453

Hair loss occurs in many people, so it can reduce the cosmetic function and protect the body and head from the environment. Hair loss is a disorder in which the number of hairs is less or more than normal. Hair tonic includes cosmetic preparations that have a liquid form with the function of maintaining hair health, stimulating hair growth, and strengthening hair. Caffeine is a substance that can stimulate hair growth. The purpose of this study was to determine the activity of a hair tonic preparation containing caffeine that can stimulate hair growth in guinea pigs. The results showed that hair tonic caffeine Formula 1 with a concentration of 0.001% with an average hair length of 18.294 mm had high effectiveness in stimulating hair growth compared to Formula 2 with a concentration of 0.005% with an average hair length of 16.610 mm.

Formulasi dan Evaluasi Masker Hyrogel Ekstrak Etanol Pegagan (Centella Asiatica (L). Urb) Sebagai Antiaging dengan Variasi Basis Carbopol dan HPMC Vina Purnamasari M; Nurlina Nurlina; Anita Sari Anwar
Journal of Pharmaceutical and Health Research Vol 4 No 2 (2023): June 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i2.3644

Gotu kola ethanol extract (Centella asiaticaI (L)urb.) has very strong antioxidant activity with an IC50 value of 20.43 μg/ml which can be utilized in the development of pharmaceutical or cosmetic preparations. The purpose of this study was to formulate and evaluate a pharmacologically stable preparation of hydrogel antiaging mask of gotu kola ethanol extract (Centella asiaticaI (L)urb.). The research design used by varying the concentration of carbopol and HPMC was then carried out physical evaluations such as organoleptis, homogeneity, ph measurement, viscosity and flow type tests, adhesion tests, dispersion tests, weight and size tests of hydrogel masks, inflating power tests and shrinkage tests and stability tests. The evaluation results showed that gotu kola ethanol extract (Centella asiaticaI (L)urb.) that met the pharmaceutical stability test was formula 2 with a carbopol concentration of 1.25% and HPMC 2.25%.

POTENSI ANTIBAKTERI EKSTRAK ETANOL KULIT BATANG SALAM (Syzygium polyanthum) SEBAGAI AGEN ANTIACNE TERHADAP Cutibacterium acnes, Staphylococcus aureus DAN Staphylococcus epidermidis Nuraqidah Nuraqidah; Ahmad Najib; Mirawati Mirawati; Iskandar Zulkarnain Mahmud Bade; Nurul Ilmi Ainun Nissa; Nurlina Nurlina
As-Syifaa Jurnal Farmasi Vol 18, No 1 (2026): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v18i1.1365

Jerawat merupakan gangguan kulit inflamasi yang disebabkan oleh kolonisasi bakteri seperti Propionibacterium acnes, Staphylococcus aureus, dan Staphylococcus epidermidis. Penggunaan antibiotik topikal secara terus-menerus dapat memicu resistensi, sehingga diperlukan alternatif alami yang aman dan efektif. Salah satu tanaman obat yang berpotensi adalah kulit batang salam (Syzygium polyanthum), yang diketahui mengandung senyawa aktif dengan efek antibakteri. Penelitian ini bertujuan untuk mengevaluasi aktivitas antibakteri ekstrak etanol kulit batang salam terhadap bakteri penyebab jerawat. Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 70%. Skrining fitokimia dilakukan dengan metode Kromatografi Lapis Tipis (KLT), sedangkan uji aktivitas antibakteri mencakup skrining bakteri, penentuan Konsentrasi Hambat Minimum (KHM) dan Konsentrasi Bunuh Minimum (KBM), serta uji difusi agar menggunakan cakram kertas. Hasil skrining fitokimia menunjukkan bahwa ekstrak positif mengandung alkaloid, flavonoid, steroid, dan fenolik. Aktivitas antibakteri yang signifikan diperoleh terhadap P. acnes, S. aureus, dan S. epidermidis dengan nilai KHM berturut-turut sebesar 0,4%; 0,8%; dan 0,2%, serta nilai KBM masing-masing sebesar 0,8%; 1,6%; dan 0,4%. Zona hambat terbesar diperoleh pada bakteri S. epidermidis. Temuan ini menunjukkan bahwa ekstrak kulit batang salam memiliki potensi sebagai agen topikal antiacne dari bahan alam.

PKM PRODUKSI TEH HERBAL DARI KOMBINASI DAUN DAN BUNGA KERSEN (Muntingia calabura L.) PADA IBU PKK DI DESA PADDINGIN KAB. TAKALAR Masdiana Tahir; Asriani Suhaenah; Nurlina; Safruddin
JURNAL PENGABDIAN MASYARAKAT YAMASI Vol. 4 No. 2 (2025): Jurnal Pengabdian Masyarakat Yamasi
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/v47e7g03

Tanaman kersen banyak tumbuh di daerah desa Paddingin Kec. Sanrobone, Kab.Takalar yang terlihat disepanjang jalan desa sebagai tanaman pelindung. Daun dan bunga kersen telah terbukti mengandung banyak senyawa kimia yang dapat memberikan aktivitas farmakologis seperti antidiabetes, antikolesterol, antibakteri, dan antioksidan, Berdasarkan hasil survei diketahui bahwa penyakit diabetes, kolesterol, asam urat dan tekanan darah merupakan penyakit yang masuk dalam 10 besar terbanyak yang diderita oleh masyarakat di desa Paddingin. Sehingga masyarakat perlu diedukasi cara penanganan dan pencegahannya dengan pemanfaatan tanaman kersen sebagai alternatif pengobatan tanpa menggunakan obat kimia yang memiliki efek samping. Tujuan PKM ini adalah untuk memberikan pengetahuan dan keterampilan IPTEK pembuatan teh herbal dari kombinasi daun dan bunga kersen pada mitra ibu PKK desa Paddingin. Pelaksanaan kegiatan PKM ini diawali dengan tahap pre test kemudian penyuluhan tentang manfaat kersen dan sediaan teh herbal. Selanjutnya dilakukan pelatihan cara membuat produk teh herbal dalam kantong teh celup dan dikemas dalam pouch yang diberi label agar bernilai komersial, yang dipraktekkan langsung oleh peserta. Tahap berikutnya adalah uji hedonik untuk mengukur tingkat kesukaan pada produk teh herbal yang telah dibuat dan diperoleh hasil 95% peserta memilih suka dan 5% memilih sangat suka dan 0% yang memilih agak suka dan tidak suka. Tahap terakhir evaluasi dengan melakukan post test dan tanya jawab. Hasil evaluasi menjukkan adanya peningkatan pengetahuan sebesar 75% dan keterampilan sebesar 100% dalam mengolah tanaman kersen dengan memanfaatkan daun peserta dan bunganya menjadi produk teh herbal yang bermanfaat bagi kesehatan. Dengan dilakukannya kegiatan PKM ini diharapkan ibu-ibu PKK desa Paddingin dapat membuat produk teh herbal dari kersen secara mandiri dirumah untuk kebutuhan pengobatan sendiri serta keluarga dan dapat memberi peluang wirausaha untuk membantu perekonomian keluarga.

Co-Authors A Hasrawati Ahmad Najib Andi Almayra Putri Awalia Andi Emelda Andi Maulana Kamri Andi Nadilla Arfah Anita Sari Anwar Arnilasari Arnilasari Asriani Suhaenah Aztriana Aztriana, Aztriana Bayu Putra Dian Safitri Achmad Faisal Attamimi Irma Santi Iskandar Zulkarnain Mahmud Bade Isnayanti Isnayanti Kurnia Arinar Pramentari M Ilham Tomagola M. Ilham Tomagola Masdiana Tahir Mirawati Mirawati Mirawati Mirawati Nuraqidah Nuraqidah Nurul Ilmi Ainun Nissa Rezeki Muamar Riskawati Angraini Rosvina Rosvina Rusli, Rusli Safruddin Saiful Bahri Vina Purnamasari M

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