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All Journal Global Medical and Health Communication Media Ilmu Kesehatan Jurnal Biomedika dan Kesehatan Jurnal Pengabdian Nasional (JPN) Indonesia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Abdimas Kesehatan Terpadu Jurnal Pengabdian Nasional (JPN) Indonesia

Meiyanti Meiyanti

Department Of Pharmacology And Medical Pharmacy, Faculty Of Medicine, Universitas Trisakti, Jakarta

Author-ID : 2673215

Religion Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Effect of Phaleria macrocarpa (Scheff.) Boerl Dry Extract to the Level of Malondialdehyde Meiyanti Meiyanti; Eveline Margo; Juni Chudri
Global Medical & Health Communication (GMHC) Vol 8, No 1 (2020)
Publisher : Universitas Islam Bandung

Increased age causes an increase in degenerative diseases. Antioxidants in the body unable to neutralize the increased concentration of free radicals. The flesh of the Phaleria macrocarpa (Scheff.) Boerl contains flavonoids which have antioxidant effects. At present, there are still very limited clinical trials of Phaleria macrocarpa (Scheff.) Boerl. This study was an experimental pretest and posttest involving 30 healthy volunteers receiving glucose loads in November 2018–February 2019 in Jakarta. This study aimed to assess the antioxidant effect of Phaleria macrocarpa (Scheff.) Boerl dry fruit extract in various dosage ranges. Subjects of this study aged 30–55 years. The data collection included anthropometric examination and malondialdehyde levels before and after administration of dry fruit extract doses of 62.5 mg, 125 mg, and 250 mg at 150 minutes after oral glucose induction. Data analysis using a paired t test with p<0.05. Decreased levels of malondialdehyde in the administration of Phaleria macrocarpa (Scheff.) Boerl with a dose of 62.5 mg, 125 mg, and 250 mg by 40.9%, 22.9%, and 18.3% compared to the baseline malondialdehyde level (1,608 nmol/mL). Statistical analysis using a paired t test showed p=0.000 for all three doses compared with baseline levels. Dry fruit extract of Phaleria macrocarpa (Scheff.) Boerl has an antioxidant effect; the antioxidant effect of the extract is not directly proportional to the dose. EFEK ANTIOKSIDAN EKSTRAK KERING PHALERIA MACROCARPA (SCHEFF.) BOERL TERHADAP KADAR MALONDIALDEHIDPertambahan usia menyebabkan peningkatan penyakit degeneratif. Antioksidan dalam tubuh tidak mampu menetralkan peningkatan konsentrasi radikal bebas. Daging buah Phaleria macrocarpa (Scheff.) Boerl mengandung flavonoid mempunyai efek antioksidan. Saat ini masih sangat terbatas uji klinis Phaleria macrocarpa (Scheff.) Boerl. Penelitian ini merupakan uji eksperimental sebelum dan sesudah perlakuan pada 30 sukarelawan sehat yang diinduksi dengan glukosa yang dilaksanakan pada bulan November 2018–Februari 2019 di Jakarta. Penelitian ini bertujuan menilai efek antioksidan ekstrak kering buah Phaleria macrocarpa (Scheff.) Boerl dalam beberapa kisaran dosis yang diberikan. Subjek penelitian berusia 30–55 tahun. Pengumpulan data meliputi pemeriksaan antropometri serta kadar malondialdehid sebelum dan sesudah pemberian ekstrak kering dosis 62,5 mg, 125 mg, dan 250 mg pada menit 150 setelah dilakukan induksi glukosa oral. Analisis data menggunakan uji t berpasangan dengan p<0,05. Penurunan kadar malondialdehid pada pemberian ekstrak Phaleria macrocarpa (Scheff.) Boerl dosis 62,5 mg, 125 mg, dan 250 mg sebesar 40,9%, 22,9%, dan 18,3% dibanding dengan kadar malondialdehid sebelum pemberian (1.608 nmol/mL). Analisis statistik menggunakan uji t berpasangan didapatkan p=0,000 untuk ketiga dosis dibanding dengan kadar awal. Ekstrak kering buah Phaleria macrocarpa (Scheff.) Boerl mempunyai efek antioksidan; efek antioksidan ekstrak tidak berbanding lurus dengan dosis.

Factors Associated to Growth Disorder in Children with Thalassemia Major Nurbaiti Annisaa Soegiharto; Meiyanti Meiyanti
Global Medical & Health Communication (GMHC) Vol 9, No 2 (2021)
Publisher : Universitas Islam Bandung

Growth disorders in short stature are often found in patients with β-thalassemia major. It is caused by several factors such as hypoxia, hemosiderosis, deficiency of nutritional intake, and micronutrient. Disorder in growth will affect the patient's quality of life. This study aims to determine the prevalence of growth disorders and analyze the factors associated with thalassemia child growth disorders. This study used an observational analytic study with a cross-sectional design on 167 patients with β-thalassemia major at the Palang Merah Indonesia Hospital, Bogor, West Java, in October–December 2018. Data was collected using a transfusion compliance questionnaire and the Morisky Medication Adherence Scale (MMAS-8), while growth was assessed using the CDC 2000 height/age curve. Data analysis used SPSS for Windows version 21.0. Of 167 subjects, 86 subjects (51.5%) were not adherent to transfusion, 97 subjects (58.1%) had low consumption of chelation iron, and 146 subjects (87.4%) had growth problems. The results of bivariate data analysis using the chi-square test for transfusion compliance and parental education on growth obtained p=0.000 and p=0.032. Likewise, for compliance with iron chelation consumption and parents' income to growth, the p value=0.000 was obtained. It was concluded that the prevalence of growth disorders was 87.4%, and there was a relationship between transfusion compliance, parental education level, parents' income, and compliance with iron chelation consumption on growth disorders in thalassemia children. FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN PERTUMBUHAN PADA ANAK TALASEMIA MAYORGangguan pertumbuhan berupa perawakan pendek sering ditemukan pada penderita talasemia β mayor. Hal ini disebabkan oleh beberapa faktor seperti hipoksia, hemosiderosis, kekurangan asupan nutrisi, dan mikonutrien. Gangguan pertumbuhan akan memengaruhi kualitas hidup pasien. Penelitian ini bertujuan mengetahui prevalensi gangguan tumbuh kembang dan menganalisis faktor-faktor yang berhubungan dengan gangguan tumbuh kembang anak talasemia. Penelitian ini menggunakan jenis penelitian observasional analitik dengan desain cross-sectional pada 167 pasien talasemia β mayor di RS Palang Merah Indonesia, Bogor, Jawa Barat pada bulan Oktober–Desember 2018. Pengumpulan data dilakukan dengan menggunakan kuesioner kepatuhan transfusi dan Morisky Medication Adherence Scale (MMAS-8), sedangkan pertumbuhan dinilai menggunakan kurva tinggi/usia CDC 2000. Analisis data menggunakan SPSS for Windows versi 21.0. Dari 167 subjek, 86 subjek (51,5%) tidak patuh pada transfusi, 97 subjek (58,1%) memiliki konsumsi kelasi besi rendah, dan 146 subjek (87,4%) mengalami gangguan pertumbuhan. Hasil analisis data bivariat menggunakan uji chi-square untuk kepatuhan transfusi dan pendidikan orangtua tentang pertumbuhan diperoleh p=0,000 dan p=0,032. Begitu pula untuk kepatuhan konsumsi kelasi besi dan pendapatan orangtua terhadap pertumbuhan diperoleh p=0,000. Disimpulkan bahwa prevalensi gangguan tumbuh kembang sebesar 87,4% dan terdapat hubungan kepatuhan transfusi, tingkat pendidikan orangtua, pendapatan orangtua, dan kepatuhan konsumsi kelasi besi dengan gangguan tumbuh kembang anak talasemia.

HUBUNGAN FUNGSI KOGNITIF DENGAN KUALITAS HIDUP PADA LANSIA Juan Stuart; Meiyanti
MEDIA ILMU KESEHATAN Vol 9 No 3 (2020): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v9i3.290

Background: The aging process could cause physical changes and lowered organ function. These changescan affect the quality of life of the elderly, such as impaired cognitive function. It was found that there are pros and cons of whether or not thecognitive function have relates with quality of life of the elderly. Objective: To know the relationship between cognitive function and quality of life. Methods: This research is a descriptive study of analytic with crosssectional design with the number of respondents as many as 124 elderly, aged ≥ 60 years in Panti sosial tresna werdha 4 Cengkareng, West Jakarta. By using MMSE questionnaire to assess cognitive function and WHOQOL-BREF for quality of life. Results:Respondents were most acquired aged 60-74 years (81.5%), female gender (59.7%), as well as the level of education under high School (79.8%). The results of the study of the relationship test between cognitive function and quality of life is p=0.003 in the physical aspect, p=0.000 in psychological, p=0.004 in social and p=0.002 in the environmental aspects of the quality of life. Conclusion: Cognitive function affects all aspects of quality of life in elderly.

Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia Meiyanti Meiyanti; Oktavianus Ch Salim; Elly Herwana; Joice V kalumpiu; Murad Lesmana
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 3, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss3.art4

Background: The rapid increase of antibiotic resistance among enteric pathogens in developing countries has become a great concern. In Indonesia, Salmonella, Shigella, and Vibro are still an important public health problem. Objectives: The purpose of this study was to determine the antibiotic resistance patterns of several diarrhea-causing enteric bacteria that are frequently found in Indonesia, particularly Salmonella, Shigella and Vibrio. Methods: A cross-sectional study was conducted , among 150 rectal swabs collected from patients with diarrhea, the enteric pathogens isolated comprised Shigella (11.4%), Salmonella (6.6%) and Vibrio(2.7%). Results: Antibiotic susceptibility test on Shigella species to several antibiotics such as ampicillin, chloramphenicol, tetracycline and, trimethoprim-sulfamethoxazole showed a considerably high resistance rate (25%-100%), whereas ceftriaxone, ciprofloxacin, norfloxacin and nalidixic acid were apparently still effective (resistance rate 0%). Non-typhoid Salmonella had similar resistance patterns as those of Shigella, particularly to ampicillin, tetracycline, chloramphenicol and trimethoprim- sulfamethoxazole However, for S. typhi it was found that all antibiotics were still effective. Vibrio was resistant to ampicillin (resistance rate 100%), whereas the other antibiotics were still effective. Conclusion: It may be concluded that for each of the enteric pathogens the antibiotic resistance pattern should be determined. Use of antibiotics should be based on the antibiotic susceptibility tests.

Association between heel-height and low back pain in sales promotion girls Andhika Rezky Bahrizal; Meiyanti Meiyanti
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 8, No 3, (2017)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol8.Iss3.art9

Background: The Prevalence of LBP in Indonesia continues to increase, while the exact cause cannot be identified. The facts show that most of LBP is caused by occupational health problems rather than organic diseases, which one of them is the habit of wearing high-heeled shoes. Besides having an aesthetic function, high-heeled shoes also give negative effects on health. Objective: To evaluate the association between the usage and duration of high heels with LBP, as well as evaluating disability due to LBP in female salespersonMethods: The study used analytic observational study with cross-sectional design that includes 123 sales promotion girls in one of department stores, Cengkareng, West Jakarta which was carried out from November to December 2015. The data was collected through the interview which includes characteristics of the subjects, complaint history of low back pain (LBP), measurement of heel heights, and anthropometry data. The intensity of pain is assessed by Visual Analogue Scale, whilst the degree of disability is assessed by using Oswestry Low Back Pain Disability Questionnaire. Data analysis is performed by using Fisher’s test with a significance level p<0.05 software SPSS for Windows version 21.Results: The majority of 20 to 25-year-old sales promotion girls with a normal nutritional status wear 5-7 cm-high-heeled shoes for more than one year. About 68% of them complain of low back pain (LBP), where 11% of subjects were obtained with suspected disability due to LBP complaint. The heel heights is not correlated with LPB complaints, but the working period of sales promotion girls is (p=0.000).Conclusion: There is no correlation between high heel shoes with low back pain. There is a relationship between the working period with low back pain.

Hubungan menopause dengan depresi pada wanita diatas 50 tahun Carla Octavani; Meiyanti Meiyanti
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 10, No 1, (2019)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol10.Iss1.art8

Background: Depression is a significant contributor to the global burden of disease and affects people in all communities across the world. Today, depression is estimated to affect 350 million people with apercentage of 50% higher for females than males. Several theories have been proposed to explain this phenomenon which includes biological, psychological, and social factors. Some researchers conclude the prevalence of depression is quite high in women, especially when a woman reaches her menopause period.Objective: This study aims to know the relationship between menopause and depression among female above 50 years old.Methods: An analytical observational study with a cross-sectional design was carried out from August to October 2016. The samples were selected using non-probability sampling, consecutive sampling method of 108 subjects. Data were collected using a questionnaire which included the characteristics of the subject (age, education, occupation, menopausal state) and the Beck Depression Inventory to measure the level of depression. Chi-Square test and Fisher test were used to analyse data with the significance test at p< 0.05.Results: A total of 56 (51.9%) subjects aged 50-60 years and as many as 85 subjects (78.7%) experienced menopause. The prevalence of menopause and depression among women above 50 years old is 20%. The statistical analysis showed there was no significant correlation between two variables (p=1).Conclusion: There is no correlation between menopause and depression among women above 50 years old.

Sleep quality and attention of senior high school students Christine Kurniawan; Meiyanti Meiyanti
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art3

Background: A successful learning process can be influenced by an individual’s attention level that can affect his/her concentration level and memory capacity. Some psychological and neurological aspects contribute to the attention level. If an individual experiences attention disorder, he/she can be difficult to learn and work efficiently. One of factors that may affect the individual’s attention is sleeping quality. A sufficient sleeping quality plays an important role in an individual’s development and daily activities.Objective: This study aims to analyse relationships between the sleeping quality and the attention of students to improve their learning performances.Methods: This study was an observational analysis study with a cross-sectional design that involved 87 senior high school students. The inclusion criteria of this study were male/female students between 14 to 19 years old who were willing to be respondents by signing informed consent form. Its exclusion criteria were male/female students who were experiencing brain-related injuries and who were on medical treatment causing drowsiness such as influenza drugs, cough syrups and sleeping pills. This study was conducted for four months. The data were collected by interviews and questionnaires including identity data, educational level, Pittsburgh Sleep Quality Index valuation and digit span tests. The samples were collected with a consecutive non-random sampling method. Its data analysis was conducted by applying SPSS V.21 through Chi-Square statistical test with a significance level of 0.05.Results: Of the 87 respondents, 50.6% were females and 35.6% were 15 years old. The majority of them were at class X (10th grade). Also, 52.9% of them had low sleeping quality and 74% of them suffered bad attention. Based on the Chi-Square test, the relationship between the sleeping quality and the attention level was not significant with p value of 0.938. Conclusion: There was no a significant relationship between the sleeping quality and the attention levels on the senior high school students.

Edukasi Hidup Sehat Membiasakan Cuci Tangan Sebagai Upaya Pencegahan Penyakit Infeksi Di Era Pandemi Covid Arleen Devita; Yuliana; Ida Effendi; Meiyanti
JURNAL ABDIMAS KESEHATAN TERPADU Vol. 1 No. 2 (2022): Jurnal Abdimas Kesehatan Terpadu
Publisher : Fakultas Kedokteran Gigi, Universitas Trisakti bekerjasama dengan Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Rawa Buaya Village is one of the villages in the West Jakarta. This village is a densely populated village with a limited number of health facilities. Based on the 2018 DKI National Basic Health Research (RISKESDAS) data, the proportion of the population aged over 10 years in West Jakarta who behaved properly in washing their hands was only 49.11%. Hand washing is the most important basic technique in the prevention and control of infection transmission because it mechanically removes dirt and dust from the skin surface and reduces the number of pathogenic microorganisms. Because knowledge of clean and healthy living behavior (PHBS) by washing hands with soap is a determining factor in the transmission of infectious diseases such as diarrhea, respiratory infections including Covid-19, education is needed to increase this knowledge. Education by counseling and training activities are carried out online through the Zoom teleconference on April 23, 2022, followed by 45 village residents. Participants' knowledge was assessed by pre-test and post-test using Google Form. From the post-test’s results, there is an increase in the participants’s knowledge by 22.9% with an increase in the percentage of correct answers from the pre and post test ranging from 6.6% - 35.6%, which is also expected to change in habits or behavior.

Edukasi dan Pelatihan Pengolahan Tanaman Obat Untuk Menunjang Kesehatan Masyarakat Kelurahan Angke Meiyanti; Yohana; Eveline Margo; Erlani Kartadinata; Juni Chudri
Jurnal Pengabdian Nasional (JPN) Indonesia Vol. 4 No. 2 (2023): Mei
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LPPM) AMIK Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35870/jpni.v4i2.271

The utilization of traditional medicine derived from nature has increased its use in recent years, this is in line with the current trend of returning to nature. The use of traditional medicine in the form of herbal medicine has been done since ancient times and has been passed down from generation to generation. However, the use of TOGA as medicine is still low in prevalence, especially in the DKI Jakarta area according to 2018 Riskesdas data. The level of knowledge is one of the factors associated with the utilization of herbal medicine. Limited knowledge about medicinal plants and how to process and make herbal medicines properly and correctly becomes an obstacle to utilization. Various benefits can be obtained from the utilization of TOGA both in terms of benefits, safety, and economic aspects, especially for community groups with economic limitations. This community service activity is carried out by providing education on useful medicinal plants, and plant parts that can be used as medicines and training on processing medicinal plants using household appliances. The purpose of this activity is to increase knowledge, utilization, and interest in processing medicinal plants.

Peningkatan Pengetahuan mengenai Bahaya dan Risiko Gangguan Pernapasan pada Pengemudi Ojek Online Arleen Devita; Yuliana; Ida Effendi; Hans Utama Sutanto; Meiyanti
JURNAL ABDIMAS KESEHATAN TERPADU Vol. 2 No. 1 (2023): Jurnal Abdimas Kesehatan Terpadu
Publisher : Fakultas Kedokteran Gigi, Universitas Trisakti bekerjasama dengan Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jakt.v2i1.16794

Jakarta is listed as one of the cities in the world with the most polluted air quality, with an annual average PM 2.5 of 49.4 g/mÂ³ in 2019. The sources of air pollution in Jakarta among others are the large number of motor vehicles that are not in accordance with the guidelines of safe vehicles for the environment. Not to mention air pollution from industries and factories fueled by coal or other fossils. Online motorcycle taxi drivers are a profession that is at risk of experiencing the effects of this air pollution. Respiratory disorders that can occur such as acute respiratory infections, chronic obstructive pulmonary disease (COPD), decreased lung function and lung malignancy. To reduce the risk of respiratory problems that can arise in online motorcycle taxi drivers, efforts are being made to prevent and stop exposure to air pollutants through counseling activities which carried out on November 12, 2023. This activity was attended by 42 online motorcycle taxi drivers. Participants' knowledge was assessed by pre-test and post-test using the Google form to assess participants' cognitive changes. From the results of the pre-test and post-test evaluation, it was found that there was an increase in knowledge about the risks and respiratory tract disorders that could arise, namely 25.5%, with an increasing percentage of correct answers of pre-test and post-test ranging from 4.8 % - 40.5%. It is hoped that this increased knowledge will change the behavior of online motorcycle taxi drivers to always pay attention of prevention and stop exposure to air pollutants.

Co-Authors Andhika Rezky Bahrizal Carla Octavani Christine Kurniawan Devita, Arleen Effendi, Ida Elly Herwana Erlani Kartadinata Eveline Margo Eveline Margo Hans Utama Sutanto Joice V kalumpiu Juan Stuart Juni Chudri Mochamad Reiza Adiyasa Murad Lesmana Nurbaiti Annisaa Soegiharto Oktavianus Ch Salim Tinalda Nur Amelia Wijaya Yohana Yuliana, Yuliana

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