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All Journal JURNAL PIJAR Jurnal Lembaga Penelitian Universitas Mataram Transformasi: Jurnal Pengabdian Masyarakat Jurnal Penelitian Pendidikan IPA (JPPIPA) ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemistry Jurnal Pengabdian Magister Pendidikan IPA Indonesian Physical Review Acta Chimica Asiana Jurnal Warta Desa (JWD) Prosiding Konferensi Nasional PKM-CSR Jurnal Pijar MIPA Jurnal Pepadu Jurnal Pendidikan dan Pengabdian Masyarakat Jurnal Pengabdian Inovasi Masyarakat Indonesia
Saprini Hamdiani
Department Of Chemistry, Faculty Of Mathematics And Natural Science, University Of Mataram, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Environmental Science Materials Science & Nanotechnology Mathematics Nursing Physics Public Health Social Sciences Other

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Journal : Acta Chimica Asiana

 1 
Theoretical study on the binding selectivity of 18-membered azacrown ethers with alkaline earth metal species Saprini Hamdiani; Lalu Rudyat Telly Savalas; Agus Abhi Purwoko; Saprizal Hadisaputra
Acta Chimica Asiana Vol. 1 No. 1 (2018)
Publisher : Chemistry Education Program, the University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (859.878 KB) | DOI: 10.29303/aca.v1i1.5

Abstract

The binding selectivity of 18-membered azacrown ethers (monoaza- N1, diaza- N2, triaza- N3, tetraaza- N4, pentaaza- N5, and hexaaza-18-crown-6 N6) with Ca2+, Sr2+, Ba2+ have been studied by density functional theory (DFT) calculations. The complex binding selectivity was analyzed in term of interaction energies, thermodynamic properties, second order interaction energies, and charge transfer effects. The geometrical study shows that Ca2+ and azacrown complexes acquire envelope like structure, leading to shorter bond lengths. As a result, these complex systems have the highest interaction energies. Theoretical study also showed that N6 complex with alkaline earth metal ion were shown to be more stable complex than those ligand with lower nitrogen number. The interaction energy order is N0 < N1 < N2 < N3 < N4 < N5 < N6. This trend shows that the presence of more nitrogen on the crown ether cavity increases the interaction energies by approx. 7.3 % in going from N0 to N6. It is clearly showed that the contribution of the number of nitrogen play a dominant role in the binding selectivity of these systems.
Synthesis Of Paramagnetic Merkapto Silica Hybrid From Rice Husk Ash For Ag(I) Adsorben Saral Dwi Miftiyati; Saprini Hamdiani; Made Ganesh Darmayanti
Acta Chimica Asiana Vol. 1 No. 2 (2018)
Publisher : Chemistry Education Program, the University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v1i2.19

Abstract

A study has been conducted on the synthesis of paramagnetic mercapto silica hybrids as metal adsorbent of Ag(I). The aim of this study was to synthesis paramagnetic mercapto silica hybrid from rice husk ash waste, knowing the characteristics of paramagnetic mercapto silica hybrid from rice husk ash waste, and to determine the effect of pH, metal ions concentration, and the contact time on the value of adsorption capacity (Q). Based on the results of the study, it was found that paramagnetic mercapto silica hybrids can be synthesized from the rice husk ash waste. Characterization using FTIR spectroscopy showed that silanol (Si-OH), siloxan (Si-O-Si), -SH, and Fe-OH functional groups, and characterization of paramagnetic mercapto silica hybrid structures using XRD to show crystalline compounds with a position value of 2θ = 35.4 which showed that the magnetite material of Fe3O4 was coated by silica. Paramagnetic mercapto silica hybrids from rice husk waste can be used as adsorbent of Ag (I) metal at optimum conditions of pH 3, contact time of 120 minutes, and adsorption capacity of 392.01 mg/g. The suitable isotherm model is the Freundlich isotherm model which means the absorption of metal Ag (I) occurs physically, while adsorption of kinetics followed the pseudo II order kinetic model with a value of k = 3.01 g.mg-1 minute-1.
Synthesis Of Mesoporiic Silica From Rice Husk Ash For Pinostrobin Based Drug Delivery Rifia Wulandari; Saprini Hamdiani; Nurul Ismillayli
Acta Chimica Asiana Vol. 2 No. 1 (2019)
Publisher : Chemistry Education Program, the University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v2i1.20

Abstract

A study has been conducted on the synthesis of mesoporous silica as introductory material pinostrobin anticancer compounds. The aim of this study was to synthesis paramagnetic mesoporous silica from rice husk ash waste; knowing the characteristics of silica gel and mesoporous silica from rice husk and the value of adsorption capacity (Q). Based on the results of the study, it was found that mesoporous silica can be synthesized from the rice husk ash waste. Characterization using FTIR produces silanol (Si-OH), and siloxan (Si-O-Si). The use of 30% w/w tartaric acid as a template doesn’t change the functional groups of silica. The optimum conditions of adsorption of pinostrobin compounds by mesoporous silica at the adsorption capacity of 7.049 mg/g. In simulated intestinal fluids (pH 7.4),pinostrobin is released slowly at every hour, then slightly increases at the 10th hour and continues to increase again slowly so that the pinostrobin compound is completely released at 12 hours.
Synthesis of Rice Husk Mesoporous Silica as pH Responsive Release Material Pidia Aulia; Saprini Hamdiani; Iwan Sumarlan
Acta Chimica Asiana Vol. 2 No. 2 (2019)
Publisher : Chemistry Education Program, the University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (392.026 KB) | DOI: 10.29303/aca.v2i2.21

Abstract

The synthesis of mesoporous silica as a delivery agent for the ethyl para-methoxycinnamate has been carried out. The study aims to determine the process of mesoporous silica synthesis from sodium silicate from the smelting of rice husk ash, determine the adsorption capacity of mesoporous silica in the ethyl para-methoxycinnamate and the pH responsive release of ethyl para-methoxycinnamate with mesoporous silica as a delivery agent in simulated intestinal and gastric fluids. It was found that mesoporous silica can be synthesized from rice husk ash with a 30% tartaric acid template. Characterization of mesoporous silica using FTIR spectroscopy showed the presence of silanol (Si-OH) and siloxane (Si-O-Si) functional groups. Mesoporous silica from rice husk ash is able as adsorbent for the ethyl para-methoxycinnamate with the adsorption capacity of 8.26 mg/g. The release test of gastric simulation fluid (pH 1.2) showed that the ethyl-para-methoxycinnamate was released from silica for a period of 12 hours. In the intestinal simulation fluid (pH 7.4), the release of the ethyl para-methoxycinnamate occurred slowly at the first hour, then gradually increased at 5 hour up to 12 hour.
Thermodynamics and Kinetics of Adoption of Ag (I) on Paramagnetic Silica Rice Husk Ash Surface Wardian Antoni; Saprini Hamdiani; Siti Raudhatul Kamali
Acta Chimica Asiana Vol. 2 No. 1 (2019)
Publisher : Chemistry Education Program, the University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v2i1.32

Abstract

Synthesis of paramagnetic silica from rice husk ash has been carried out as an adsorbent for heavy metal Ag (I). This study tried to synthesis and characterized the thermodynamics and kinetics behaviour of paramagnetic silica from the husk ash as metal adsorbent Ag (I). Determination of optimal conditions for adsorption of metal ions Ag (I) is carried out by varying the pH, concentration, and contact time of the adsorbent. The results showed that the optimum pH was at pH 3, optimal concentration Ag(I) of 350 ppm and optimal contact time of 90 minutes. At optimal conditions, paramagnetic silica adsorption capacity for metal ion Ag (I) is 323.62 mg/g. The isotherm model that is suitable for paramagnetic silica is the Freundlich isotherm model. The kinetic model that is suitable for paramagnetic silica is the Pseudo Order 2 kinetic model.
QSAR and Ab Initio studies of quinolon-4(1H)-imine derivatives as antimalarial agents Jafar La Kilo; Akram La Kilo; Saprini Hamdiani
Acta Chimica Asiana Vol. 4 No. 1 (2021)
Publisher : The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v4i1.39

Abstract

Malaria is still the most dangerous disease threat in the world, including in Indonesia. In Indonesia, it is estimated that there are 20 million cases of malaria per year. Malaria resistance to conventional drugs requires the search for new antimalarial drugs. Molecular modeling can be a solution to these problems. An activity study of 22 quinolone-4 (1H) -imine derivatives as antimalarials was carried out using the QSAR Quantitative Structure-Activity Relationship method. The electronic and molecular descriptors were obtained from the Hartree-Fock HF / 6-31G ab initio calculation. The multiple linear regression (MLR) method was used to construct the QSAR model. The best QSAR models produced are: pEC50 = -4,177 + (37,902 x qC3) + (171,282 x qC8) + (9,061 x qC10) + (125,818 x qC11) + (-149,125 x qC17) + (191,623 x qC18), with statistical parameters, n = 22; r2 = 0,910; SEE = 0,171; Fhit/Ftab = 4,510 dan PRESS = 0,697. The best QSAR equation model can be used as a reference for designing and predicting the antimalarial activity of Quinolon-4 (1H) -imine derivatives which have higher activity than the previous one
Co-Authors Afandi, Muhammad Rosyad Agus Abhi Purwoko Agus Abhi Purwoko Agus Abhi Purwoko Akram La Kilo Anshori, Mufid Apriani, Niza Yusnita Ariessaputra, Suthami Arisanti, Ivon Azzauri, Supyan Baiq Fadila Arlina Baiq Maysi Dwi Alvioni3 Bambang Rusdiarso Bambang Rusdiarso Bambang Rusdiarso Chen, Chang-Nan Dhony Hermanto Dina Asnawati Eka Junaidi Eko Sri Kunarti Elsa, Putri Emmy Yuanita Emmy Yuanita Faturrahman Febriansyah, Dimas Raga Ganesh Darmayanti Hidayatullah, M. Riski I Made Sudarma I MADE SUDARMA Indriyatno Iriando, Mahadi Muhammad Gunadharma Iwan Sumarlan Izzah, Bidayatul Jafar La Kilo Jannatin Arduha Jia-Yi Xu Lala Ghina Aulia Lalu Rudyat Telly Savalas Lalu Rudyat Telly Savalas Lely Kurniawati Lely Kurniawati Made Ganesh Darmayanti Mamika Ujianita Romdhini Mamika Ujianita Romdhini, Mamika Ujianita Mariana, Baiq Marliadi Susanto Masloka, Michael Jonathan Maulida, Yunia Muhammad Arsyik Kurniawan Murniati . Nian-Yi Wu Nurul Ismilayli Nurul Ismilayli, Nurul Nurul Ismillayli Nuryono Nuryono Nuryono Nuryono Nuryono Nuryono Pahrudin, Pahrudin Pidia Aulia Prihatini, Putri Jauhar Putra, Danu Eka Rifia Wulandari Ruru Honiar Saprizal Hadisaputra Saputri, Dinar Suksmayu Saral Dwi Miftiyati Sari, Ayu Purnama Silva, Shelly Melsyan Siti Raudhatul Kamali Siti Raudhatul Kamali Sri Seno Handayani Sudirman Sudirman Sudirman Sudirman Surya Hadi Ting-Yuan Ou Trihandayani, Baiq Nisrina Ulul Khairi Zuryati Ulul Khairi Zuryati Wardani, Arifta Kusuma Wardian Antoni Wirahadi, Ahmad Yasa, I Komang Permana Yeng-Fong Shih