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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Indonesian Journal of Obstetrics & Gynecology Science Journal of Midwifery Bioscientia Medicina : Journal of Biomedicine and Translational Research Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Andalas obstetrics and gynecology journal Science Midwifery Bioscientia Medicina : Journal of Biomedicine and Translational Research
Yanti, Roza Sri
Universitas Andalas
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Correlation of Neutrophil Lymphocyte Ration (NLR) Values with Severe Preeclampsia, HELLP Syndrome, and Eclampsia Indah Lisfi; Roza Sriyanti; Firdawati FIrdawati
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 2 (2023)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.2.379-390.2023

Abstract

Background: Preeclampsia (PE) is the leading cause of maternal and fetal morbidity and mortality. The disease is characterized by hypertension (≥140/90 mmHg), proteinuria, thrombocytopenia, renal failure, neurological complications, liver involvement, and fetal growth retardation. HELLP syndrome is a variant of preeclampsia that causes an increase in liver enzymes and a low platelet count. Eclampsia is the heaviest complication of preeclampsia. Neutrophil lymphocyte ratio (NLR) is part of the leukocyte type count examination which is an easy, available examination parameter and can be used as an index of the severity of systemic inflammation. This study aimed to determine the relationship of neutrophil-lymphocyte ratio (NLR) values with severe Preeclampsia, HELLP syndrome, and eclampsia.Method: This research is a comparative analytical study with a case control study approach. This research was conducted from April-November 2022. This study was conducted at the emergency room (ER) and inpatient department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Andalas – RSUP Dr. M. Djamil Padang. The study sample was part of the population that met the inclusion and exclusion criteria. The study required 108 samples, namely 27 from the severe preeclampsia group, 27 from the eclampsia group, 27 from the HELLP syndrome group, and 27 from the control group. Bivariate statistical analysis using Independent T-Test. Samples were taken by the method of consecutive sampling. The data were analyzed at a 95% confidence interval, if obtained p value<0.05 then there is a significant relationship. The Data was analyzed by the SPSS computer program.Results: The results of this study obtained neutrophil-lymphocyte ratio in eclampsia has the highest average value compared with HELLP syndrome, severe preeclampsia, and control. While HELLP syndrome has a higher mean value than severe preeclampsia and control and subsequently severe preeclampsia also has a higher mean value NLR than control. This study found a significant relationship between neutrophil-lymphocyte ratio (NLR) with severe Preeclampsia, HELLP syndrome, and eclampsia (all p values=0.000).Conclusion: This study proves that neutrophil-lymphocyte ratio (NLR) has a significant relationship with severe Preeclampsia, HELLP syndrome, and eclampsia so further research can develop this study by analyzing other factors that affect preeclampsia. For clinicians can make this study as a reference in monitoring the progression of inflammation that occurs in severe preeclampsia, HELLP syndrome, and eclampsia.
COMPARISON OF MICROBIOTA IN THREATENED PRETERM LABOR AND NORMAL PREGNANCY AT RSUP DR.M. DJAMIL PADANG Muhammad Ryfki SA; Roza Sri Yanti; Bobby Indra Utama
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.554-565.2024

Abstract

One of the threats in pregnancy is threatened preterm labor. Several studies show that thecomposition of the microbiota in the vagina of premature births and normal pregnancies is different.This study aims to determine the comparison of microbiota in pregnancies with premature parturitionand normal pregnancies at Dr M Djamil General Hospital, Padang. This research is an analyticalobservational study with a case–control study design conducted at the Department/SMF of Obstetricsand Gynecology, RSUP Dr. M. Djamil Padang from July – September 2023. The study population in thisresearch were all pregnant women with a gestational age of 20-37 weeks who were diagnosed withimminens preterm labor and normal pregnant women with a gestational age of 20-37 weeks whoreceived antenatal care at RSUP Dr. M. Djamil Padang. Respondents had vaginal swabs taken formicrobiological culture at the Biomedical Laboratory, Andalas University, Padang. There were 33respondents each in the imminence premature birth and normal pregnancy groups. Vaginal swabresults showed that the most common microorganism found in normal pregnancy was Lactobacilussp. (73%) while in threatened preterm labor Staphylococcus aureus (37%), Staphylococcus epidermidis(27%) and E.coli (15%) were more commonly found with only a small proportion of Lactobacilus sp(12%). Chi square analysis showed a significant difference between the vaginal microbiota of normalpregnant women and pregnant women with PPI. The conclusion of this study is that there is anincrease in Staphylococcus aureus, Staphylococcus epidermidis and E.coli in pregnant women on PPIwith a decrease in the number of normal flora, namely Lactobacilus spp.
Clinical Characteristics, Laboratory, Maternal and Fetal Outcomes in Pregnancy with Covid-19 at RSUP dr. M. Djamil Padang Roza Sriyanti; Heri Farnas; Dovy Djanas
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.575-584.2024

Abstract

Introduction : The data obtained from various studies about covid-19 conducted in severalhospitals in the world are currently considered not sufficient to provide a clinical picture thatoccurs in pregnancies with Covid-19 infection. The aims to provide an overview of the clinical,laboratory, maternal and fetal outcomes in pregnancy with Covid-19 infection at dr. M. DjamilPadang.Methods: This study used a descriptive design with data collection starting from March 01,2020 - March 31, 2021 based on medical record data. Carried out in a single center at RSUPdr. M. Djamil Padang in pregnant patients with confirmed Covid-19 by PCR examination.Results: Total 136 pregnant patients confirmed Covid-19 by PCR examination. Most of thesymptoms were asymptomatic (47.1%) and without any comorbidities (76.5%). There were 3patients who experienced critical symptoms (2.2%). Maternal mortality was found at 2.3% andfetal death 4.7%. The values of d-dimer and NLR were found increasing significantly,2025.35±1392.18 for d-dimer and 6.39±4.43 for NLR. Pregnancy terminations done for 77.9%patients with cesarean section is the most method (83%). There were 4 cases (3.8%) of babiesinfected with Covid-19 from mothers who had pregnancy terminations.Conclusions: Most cases had asymptomatic clinical symptoms (47.1%). There are 2.3%cases of maternal death and 4.7% cases of fetal death. Most of the pregnancy terminationswere performed by cesarean section (88%). On laboratory examination, there was a significantincrease in maternal d-dimer (2,025.35±1.392.18) and NLR (6.39±4.43) in pregnancies withCovid-19.
EARLY HAEMORRHAGE POSTPARTUM (HPP); WITH COMPLICATION DISSEMINATED INTRAVASCULAR COAGULATION, SEPSIS, ACUTE KIDNEY INJURY Rizki Oktavian; Gunawan Efri; Roza Sriyanti; Emilzon Taslim
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.620-629.2024

Abstract

 Abstarct Background : Hemorrhage Postpartum (HPP) is the leading cause of maternal death worldwide with an incidence of 5%-10% of all deliveries. 70% of cases of HPP are caused by atony of the uterus. If HPP is not handled properly, it will cause worsening of the patient's condition which causes various multiorgan complications.Objectives : To discuss the management of HPP cases complicated by DIC, sepsis and AKI.Method : case report.Case : A female patient, 36 years old, was referred from a private hospital to PONEK RSUP Dr. M. Djamil Padang with a diagnosis of decreased consciousness ec suspected sepsis in post SCTPP oi used SC 2x + post relaparotomy oi bleeding subfascia + moderate anemia. After surgery, the patient looked pale and the hemoglobin was 7, then relaparotomy was done and done B-lynch oi uterine hypotony. After relaparotomy, the patient experienced worsening then referred to the hospital. The patient arrives with hipovolemic shock + AKI + Sepsis + DIC , then the condition improvement is carried out in ROI and hysterectomy relaparotomy is performed. The patient has worsened, maximum treatment has been carried out from the intersivist, but the patient's condition continues to worsen and eventually dies.Conclusion : Early diagnosis and rapid treatment through a multidisciplinary team and the availability of an Intensive Care Unit (ICU) can prevent complications and reduce morbidity and mortality.
Dicephalus Parapagus Conjoined Twins Alfa Febrianda; Roza Sriyanti
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.815-822.2024

Abstract

Background: Conjoined twins are monoamniotic monochorionic twins resulting from incomplete division of the embryonic disk and amniotic sac. This rare condition has an incidence of 1:33,000 to 1:165,000 pregnancies. Common types include thoracopagus and omphalopagus, with less common forms like thoracoomphalopagus, pyopagus, ischiopagus, and craniopagus. Parapagus, where twins are joined at the sides with a shared pelvis and organs, occurs in less than 0.5% of cases. Case: A 27-year-old patient presented to the Fetomaternal Clinic at RSUP M. Djamil Padang, referred from Hermina Hospital, with a diagnosis of G2P1A0H1 gravid preterm and suspected conjoined twins. Ultrasound at 5 months showed two heads and one body. Initial assessment noted a family history of twins and palpable round, firm masses. Laboratory tests, Fetomaternal ultrasound, MRI, and 3D CT Scan confirmed conjoined twins (dicephalus, parapagus, dibrachius). A cesarean section was planned. Discussion: Termination involves a multidisciplinary team to manage fetal anatomical abnormalities optimally. Emergency separation has a 70% mortality rate, higher than the 20% for elective procedures. Treatment depends on cardiovascular anatomy, with higher success if only the pericardium is divided. Cardiac anomalies' severity influences prognosis, survival, and separation feasibility. Survival rates depend on the degree of union and cardiac anomalies. In cases like dicephalus, the anatomical structure often makes it unlikely for both twins to survive separation.  
Co-Authors Aldhi Aldhi Alfa Febrianda Berriandi Arwan Bobby Indra Utama Calvindra Leenesa Djanas, Dovy Dovy Djanas Emilzon Taslim Firdawati Firdawati Gunawan Efri Hafni Bachtiar Heri Farnas Heri Farnas Heri Farnas Ilmiawati, Ilmiawati Indah Lisfi Intan Julianingsih Jofril Azmi Johanes C. Mose Masrul Mayetti Mayetti Muhammad Ryfki SA Netti Suharti Nurmala Sari Dewi Primadella Fegita Puteri, Violita Dianatha Rengga Pradipta Rengga Pradipta Ressy Permatasari Revivo Rinda Pratama Rinang Mariko Rizki Oktavian Syntia Ambelina Syntia Ambelina Tria Sari Retno Asih Wikarya, Rionitara Wiwie Putri Adila Yanwirasti Yanwirasti Zuliyana Zuliyana