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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Indonesian Journal of Obstetrics & Gynecology Science Journal of Midwifery Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Andalas obstetrics and gynecology journal Jurnal Ners Science Midwifery Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Sains dan Kesehatan
Yanti, Roza Sri
Andalas University
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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COMPARISON OF MICROBIOTA IN THREATENED PRETERM LABOR AND NORMAL PREGNANCY AT RSUP DR.M. DJAMIL PADANG Muhammad Ryfki SA; Roza Sri Yanti; Bobby Indra Utama
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.554-565.2024

Abstract

One of the threats in pregnancy is threatened preterm labor. Several studies show that thecomposition of the microbiota in the vagina of premature births and normal pregnancies is different.This study aims to determine the comparison of microbiota in pregnancies with premature parturitionand normal pregnancies at Dr M Djamil General Hospital, Padang. This research is an analyticalobservational study with a case–control study design conducted at the Department/SMF of Obstetricsand Gynecology, RSUP Dr. M. Djamil Padang from July – September 2023. The study population in thisresearch were all pregnant women with a gestational age of 20-37 weeks who were diagnosed withimminens preterm labor and normal pregnant women with a gestational age of 20-37 weeks whoreceived antenatal care at RSUP Dr. M. Djamil Padang. Respondents had vaginal swabs taken formicrobiological culture at the Biomedical Laboratory, Andalas University, Padang. There were 33respondents each in the imminence premature birth and normal pregnancy groups. Vaginal swabresults showed that the most common microorganism found in normal pregnancy was Lactobacilussp. (73%) while in threatened preterm labor Staphylococcus aureus (37%), Staphylococcus epidermidis(27%) and E.coli (15%) were more commonly found with only a small proportion of Lactobacilus sp(12%). Chi square analysis showed a significant difference between the vaginal microbiota of normalpregnant women and pregnant women with PPI. The conclusion of this study is that there is anincrease in Staphylococcus aureus, Staphylococcus epidermidis and E.coli in pregnant women on PPIwith a decrease in the number of normal flora, namely Lactobacilus spp.
Clinical Characteristics, Laboratory, Maternal and Fetal Outcomes in Pregnancy with Covid-19 at RSUP dr. M. Djamil Padang Roza Sriyanti; Heri Farnas; Dovy Djanas
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.575-584.2024

Abstract

Introduction : The data obtained from various studies about covid-19 conducted in severalhospitals in the world are currently considered not sufficient to provide a clinical picture thatoccurs in pregnancies with Covid-19 infection. The aims to provide an overview of the clinical,laboratory, maternal and fetal outcomes in pregnancy with Covid-19 infection at dr. M. DjamilPadang.Methods: This study used a descriptive design with data collection starting from March 01,2020 - March 31, 2021 based on medical record data. Carried out in a single center at RSUPdr. M. Djamil Padang in pregnant patients with confirmed Covid-19 by PCR examination.Results: Total 136 pregnant patients confirmed Covid-19 by PCR examination. Most of thesymptoms were asymptomatic (47.1%) and without any comorbidities (76.5%). There were 3patients who experienced critical symptoms (2.2%). Maternal mortality was found at 2.3% andfetal death 4.7%. The values of d-dimer and NLR were found increasing significantly,2025.35±1392.18 for d-dimer and 6.39±4.43 for NLR. Pregnancy terminations done for 77.9%patients with cesarean section is the most method (83%). There were 4 cases (3.8%) of babiesinfected with Covid-19 from mothers who had pregnancy terminations.Conclusions: Most cases had asymptomatic clinical symptoms (47.1%). There are 2.3%cases of maternal death and 4.7% cases of fetal death. Most of the pregnancy terminationswere performed by cesarean section (88%). On laboratory examination, there was a significantincrease in maternal d-dimer (2,025.35±1.392.18) and NLR (6.39±4.43) in pregnancies withCovid-19.
EARLY HAEMORRHAGE POSTPARTUM (HPP); WITH COMPLICATION DISSEMINATED INTRAVASCULAR COAGULATION, SEPSIS, ACUTE KIDNEY INJURY Rizki Oktavian; Gunawan Efri; Roza Sriyanti; Emilzon Taslim
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.620-629.2024

Abstract

 Abstarct Background : Hemorrhage Postpartum (HPP) is the leading cause of maternal death worldwide with an incidence of 5%-10% of all deliveries. 70% of cases of HPP are caused by atony of the uterus. If HPP is not handled properly, it will cause worsening of the patient's condition which causes various multiorgan complications.Objectives : To discuss the management of HPP cases complicated by DIC, sepsis and AKI.Method : case report.Case : A female patient, 36 years old, was referred from a private hospital to PONEK RSUP Dr. M. Djamil Padang with a diagnosis of decreased consciousness ec suspected sepsis in post SCTPP oi used SC 2x + post relaparotomy oi bleeding subfascia + moderate anemia. After surgery, the patient looked pale and the hemoglobin was 7, then relaparotomy was done and done B-lynch oi uterine hypotony. After relaparotomy, the patient experienced worsening then referred to the hospital. The patient arrives with hipovolemic shock + AKI + Sepsis + DIC , then the condition improvement is carried out in ROI and hysterectomy relaparotomy is performed. The patient has worsened, maximum treatment has been carried out from the intersivist, but the patient's condition continues to worsen and eventually dies.Conclusion : Early diagnosis and rapid treatment through a multidisciplinary team and the availability of an Intensive Care Unit (ICU) can prevent complications and reduce morbidity and mortality.
Dicephalus Parapagus Conjoined Twins Alfa Febrianda; Roza Sriyanti
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.815-822.2024

Abstract

Background: Conjoined twins are monoamniotic monochorionic twins resulting from incomplete division of the embryonic disk and amniotic sac. This rare condition has an incidence of 1:33,000 to 1:165,000 pregnancies. Common types include thoracopagus and omphalopagus, with less common forms like thoracoomphalopagus, pyopagus, ischiopagus, and craniopagus. Parapagus, where twins are joined at the sides with a shared pelvis and organs, occurs in less than 0.5% of cases. Case: A 27-year-old patient presented to the Fetomaternal Clinic at RSUP M. Djamil Padang, referred from Hermina Hospital, with a diagnosis of G2P1A0H1 gravid preterm and suspected conjoined twins. Ultrasound at 5 months showed two heads and one body. Initial assessment noted a family history of twins and palpable round, firm masses. Laboratory tests, Fetomaternal ultrasound, MRI, and 3D CT Scan confirmed conjoined twins (dicephalus, parapagus, dibrachius). A cesarean section was planned. Discussion: Termination involves a multidisciplinary team to manage fetal anatomical abnormalities optimally. Emergency separation has a 70% mortality rate, higher than the 20% for elective procedures. Treatment depends on cardiovascular anatomy, with higher success if only the pericardium is divided. Cardiac anomalies' severity influences prognosis, survival, and separation feasibility. Survival rates depend on the degree of union and cardiac anomalies. In cases like dicephalus, the anatomical structure often makes it unlikely for both twins to survive separation.  
Hubungan Unmet Need Dengan Kualitas Hidup Pasien Kanker Ginekologi yang Membutuhkan Perawatan Paliatif di RSUP Dr. M. Djamil Padang Mainiati Mainiati; Syamel Muhammad; Arina Widya Murni; Roza Sriyanti; Gestina Aliska; Tuti Lestari
Jurnal Ners Vol. 10 No. 3 (2026): JULI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i3.59990

Abstract

Kanker ginekologi merupakan penyakit kronis yang memerlukan perawatan holistik, termasuk perawatan paliatif. Pelayanan kesehatan yang masih berfokus pada aspek kuratif menyebabkan beberapa kebutuhan belum terpenuhi. Kebutuhan yang tidak terpenuhi (unmet need) berpotensi menurunkan kualitas hidup pasien. Penelitian ini bertujuan untuk menganalisis hubungan antara unmet need dengan kualitas hidup pasien kanker ginekologi yang membutuhkan perawatan paliatif di RSUP Dr. M. Djamil Padang. Jenis penelitian ini adalah penelitian kuantitatif dengan desain penelitian cross sectional. Penelitian dilakukan pada Mei 2025-Juni 2026 dengan jumlah sampel 55 responden yang dipilih menggunakan teknik purposive sampling. Data dikumpulkan melalui kuesioner SCNS-SF34 dan EORTC QLQ-C30 dan dianalisis dengan uji Pearson dan Spearman. Hasil univariat menunjukkan dari lima domain, unmet need ditemukan pada domain kebutuhan psikologis, serta fisik dan aktivitas sehari-hari. Sedangkan pada domain kebutuhan sistem dan informasi kesehatan, dukungan dan perawatan serta seksual kebutuhan sudah terpenuhi. Kualitas hidup buruk ditemukan pada skala fungsional dan status kesehatan umum, sedangkan pada skala gejala kualitas hidup baik. Hasil bivariat menunjukkan ada hubungan unmet need domain kebutuhan psikologis dengan kualitas hidup pada skala fungsional (r = -0,527), skala gejala (r = 0,442), dan status kesehatan umum (r = -0,508). Selain itu, unmet need domain kebutuhan fisik dan aktivitas sehari-hari juga ada hubungan dengan kualitas hidup pada skala fungsional (r = -0,577), skala gejala (r = 0,546), dan status kesehatan umum (r = -0,522). Namun, tidak ada hubungan antara unmet need domain sistem dan informasi kesehatan, domain kebutuhan dukungan dan perawatan, serta domain seksual dengan kualitas hidup (p > 0,05). Kesimpulan penelitian ini, ada hubungan unmet need domain kebutuhan psikologis serta fisik dan aktivitas sehari-hari dengan kualitas hidup pasien kanker yang membutuhkan perawatan paliatif. Kata Kunci: kanker ginekologi, perawatan paliatif, unmet need, kualitas hidup.
Analisis Faktor Risiko Indeks Massa Tubuh, Riwayat Hipertensi, dan Riwayat Preeklampsia terhadap Kejadian Preeklampsia pada Ibu Hamil Tia Tahnia; Defrin Defrin; Firdawati Firdawati; Rima Semiarty; Roza Sriyanti; Lusiana El Sinta Bustami
Jurnal Sains dan Kesehatan Vol. 10 No. 1 (2026): Juni : Jurnal Sains dan Kesehatan (JUSIKA)
Publisher : Universitas Muhamadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jusika.v10i1.1142

Abstract

Preeclampsia is a pregnancy complication that significantly contributes to maternal and neonatal morbidity and mortality worldwide. Globally, it affects approximately 3–8% of pregnancies and causes more than 70,000 maternal deaths each year. In Indonesia, preeclampsia accounts for around 30% of the 4,151 maternal deaths reported in 2024. In Padang City, there were 254 cases in 2023 and 129 cases in 2024, with Puskesmas Bungus having the highest prevalence (7.2% and 3.77%). This study aimed to analyze the association between body mass index (BMI), history of hypertension, and history of preeclampsia with the incidence of preeclampsia among pregnant women at Puskesmas Bungus, Padang. This study used a quantitative case-control design involving 50 cases and 50 controls. Data were analyzed using chi-square and logistic regression tests. The results showed significant associations between obesity (p=0.031; OR=2.897), history of preeclampsia (p=0.006; OR=13.821), and history of hypertension (p=0.002; OR=17.216) with the incidence of preeclampsia. Multivariate analysis identified history of hypertension as the most dominant factor associated with preeclampsia. This study concludes that obesity, history of hypertension, and history of preeclampsia are significant risk factors for preeclampsia among pregnant women. Strengthening early detection and routine antenatal care for high-risk pregnancies is necessary to reduce maternal complications associated with preeclampsia.
Relationship Between Perineal Wound Pain Degree and PRP Healing in Vaginal Birth Fatima Diyas Zahra; Bobby Indra Utama; Almurdi Almurdi; Roza Sri Yanti; Deddy Saputra; Nelmi Silvia
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 2 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.2.312-321.2026

Abstract

Introduction : This study aims to see the relationship between the level of perineal wound pain and healing using PRP (Platelet Rich Plasma) in Vaginal birth. Perineal wound pain causes fear of movement resulting in subinvolution, unsmooth release of the locea, bleeding, or infection. Method : This type of research is Experimental with chi-quadrath design . The intervention group received PRP injections on perineal wounds on day 1 after delivery, while the control group was the group that was not given PRP. On the 7th day, observation of the degree of pain of perineal wounds was carried out using the VAS scale (Visual Analog Scale) in both groups. Result : The results of the study obtained a value of p=0.016. Then the value of OR = 6.250 was also obtained. Conclusion : there is a significant relationship between the level of perineal wound pain and healing using PRP in Vaginal birth. From the OR score, it is known that patients who receive PRP have a 6.25 times chance of experiencing mild pain compared to patients who are not given PRP. Keywords : pain; perineal wound; PRP; Vaginal birth.
Neutrophil Gelatinase Associated Lipocalin Levels in Normal Pregnancy and Preeclampsia Subtypes Ridho Berkah Pramuditha; Vaulinne Basyir; Firdawati Firdawati; Mondale Saputra; Roza Sri Yanti; Hudila Rifa Karmia
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 2 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.2.262-270.2026

Abstract

Background: Preeclampsia is still a major cause of morbidity and mortality in pregnant women. Neutrophil gelatinase–associated lipocalin (NGAL) is a better biomarker than creatinine as a biomarker of kidney disorders and is considered as an accurate early predictor of preeclampsia. However, the results of studies related to this still vary Objective: To determine the differences in neutrophil gelatinase associated lipocalin (NGAL) expression in normal pregnancy, early-onset preeclampsia (EOP) and late-onset preeclampsia (LOP). Methods: This is a cross-sectional study conducted from April 2024 to June 2025. The samples were all pregnant women aged ≥20 weeks who came to the Obstetrics Department at Dr. M. Djamil General Hospital, Andalas University Hospital and dr. Reksodiwiryo Hospital in Padang City who met the inclusion and exclusion criteria. Patients with a history of malignancy, infection, premature rupture of membranes, or having comorbidities were excluded from the study. Patients were divided into normal pregnancy, EOP and LOP. Examination of NGAL levels from venous blood samples was carried out using the ELISA. Results: In this study, there were 12 normal pregnancies, 13 EOP pregnancies and 11 LOP pregnancies. Each group of pregnant women had almost similar characteristics with an average age of 31 years and the majority of patients being multiparous, obese, having a high school education and being housewives. In this study, NGAL levels were 2.45 ± 0.73 ng/ml; 3.61 ± 1.12 ng/ml; and 3.63 ± 1.12 in normal pregnancies, EOP, and LOP, respectively. The ANOVA test obtained p value of 0.01, which means that there is a significant difference in NGAL expression between normal pregnancies, EOP and LOP. The post hoc test obtained significant differences between NGAL level of normal pregnancy with EOP (p = 0.021) and normal pregnancy with LOP (p = 0.027), but not in NGAL expression between EOP with LOP (p = 1,000). Conclusion: Differences in NGAL expression were found to be significant between normal pregnancy and EOP and LOP. Meanwhile, there was no difference in NGAL expression between EOP and LOP.
Co-Authors Aldhi Aldhi Alfa Febrianda Almurdi Almurdi Arina Widya Murni Berriandi Arwan Bobby Indra Utama Calvindra Leenesa Deddy Saputra Defrin Defrin Djanas, Dovy Dovy Djanas Emilzon Taslim Fatima Diyas Zahra Firdawati Firdawati Firdawati Firdawati Gestina Aliska Gunawan Efri Hafni Bachtiar Heri Farnas Heri Farnas Heri Farnas Hudila Rifa Karmia Ilmiawati, Ilmiawati Indah Lisfi Intan Julianingsih Jofril Azmi Johanes C. Mose Lusiana El Sinta Bustami Mainiati Mainiati Masrul Djalal Mayetti Mayetti Mondale Saputra Muhammad Ryfki SA Nelmi Silvia Netti Suharti Nurmala Sari Dewi Primadella Fegita Puteri, Violita Dianatha Rengga Pradipta Rengga Pradipta Ressy Permatasari Revivo Rinda Pratama Ridho Berkah Pramuditha Rima Semiarty Rinang Mariko Rizki Oktavian Syamel Muhammad Syntia Ambelina Syntia Ambelina Tia Tahnia Tria Sari Retno Asih Tuti Lestari Vaulinne Basyir Wikarya, Rionitara Wiwie Putri Adila Yanwirasti Yanwirasti Zuliyana Zuliyana