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All Journal Sari Pediatri Paediatrica Indonesiana Indonesian Journal of Medicine Journal of Maternal and Child Health Jurnal Keperawatan dan Kesehatan Jurnal Ners

Dwi Hidayah

Department Of Child Health, Sebelas Maret University Medical School/Dr. Moewardi Hospital

Author-ID : 281277

Health Professions Medicine & Pharmacology Nursing Public Health

Published : 13 Documents Claim Missing Document

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Hubungan Pola Konsumsi Makanan Dengan Status Gizi Siswa Di Madrasah Ibtidaiyah Swasta (Mis) Pontianak Hidayah, Dwi; Hastuti, Lidia; Wardani, Nuniek Setyo
Jurnal Keperawatan dan Kesehatan Vol 8 No 1 (2017): JK2
Publisher : Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Latar belakang: Menciptakan sumber daya manusia yang bermutu, perlu ditata dengan memperhatikan kesehatan anak. Salah satu unsur penting kesehatan adalah masalah gizi. Status gizi dipengaruhi oleh pola konsumsi makan dan penyakit infeksi. Anak usia sekolah memiliki masa pertumbuhan dan perkembangan fisik untuk itu diperlukan status gizi yang optimal. Tujuan : Mengetahui hubungan pola konsumsi makanan dengan status gizi siswa di Madrasah Ibtidaiyah Swasta (MIS) Pontianak. Metode penelitian : Jenis penelitian bersifat analitik dengan menggunakan deskriptif analitik dengan pedekatan Cross Sectional. Teknik pengambilan sampel menggunakan teknik random sampling dengan jumlah sampel 42 orang. Analisa data bivariat menggunakan Uji Chi Square. Hasil Penelitian : Hasil dari penelitian dari 42 responden menunjukkan bahwa sebagian besar sampel memiliki pola konsumsi makanan baik sebanyak 25 orang (59,5%), anak yang pola konsumsi makanan kurang baik sebanyak  17 orang (40,5%) dan sebagian besar mempunyai gizi baik sebanyak sebanyak 37 orang (85,7%) dan anak yang berstatus gizi kurang baik sebanyak 6 orang (14,3%). Data yang diperoleh di uji statistik, didapatkan hasil bahwa nilai uji p <? (0,202 > 0,05 Kesimpulan : Penelitian ini dapat disimpulkan bahwa terdapat hubungan pola konsumsi makanan dengan status gizi di Madrasah Ibtidaiyah Swasta (MIS) Pontianak.

Comparison Neutrophil to Lymphocyte Count Ratio with C-Reactive Protein as a Predictor for Neonatal Sepsis Nugroho, Irfan Dzakir; Hidayah, Dwi; Salimo, Harsono
Indonesian Journal of Medicine Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health, Sebelas Maret University

Background: Accurate early detection of bacteriemia plays an important role in the treatment and prognosis of infected neonates, but is constrained by the limitations of specific sepsis markers for detecting bacteriemia. NLCR or neutrophil to lymphocyte count ratio in adult population shows a more sensitive parameter in predicting infection and has the advantage of being economical and widely available. The role of NLCR in the neonatal population has not been widely studied. The purpose of this study was to analyze NLCR versus CRP as a predictor of neonatal sepsis.Subjects and Method: This study take analytic observatinal with diagnostic test approach to subject with sepsis risk factor and neonatal sepsis at dr. Moewardi hospital from April until May 2017. Characteristics data as gestational age, gender, birth weight, IT ratio, leucocyte count, neutrophil and lymphocyte count, NLCR, CRP and blood culture. Data presented descriptively and statistical analysis was performed.Results: No significant correlation between subject’s characteristics and neonatal sepsis. NLCR with cutoff point for 2.22 has sensitivity, specificity, positive and negative predictive value for 87.5%, 75%, 70% and 90%, respectively. CRP with cutoff point for 0.25 has sensitivity, specificity, positive and negative predictive value for 83.3%, 55.6%, 55.6% and 83.3% respectively. While IT-rasio has sensitivity, specificity, positive and negative predictive value for 29.2%, 91.7%, 70% and 66%, respectively.Conclusion: NLCR has a satisfactory predictive value for neonatal sepsis that widely available and economic predictor alternative with cutoff point for 2.22.Keywords: NLCR, CRP, predictor, neonatal sepsisCorrespondence: Irfan Dzakir Nugroho. Masters Program in Family Medicine, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta, Central Java.Indonesian Journal of Medicine (2021), 06(01): 112-118https://doi.org/10.26911/theijmed.2021.06.02.02

Risk factors for neonatal mortality at Moewardi Hospital, Surakarta Dwi Hidayah; Yulidar Hafidh
Paediatrica Indonesiana Vol 54 No 4 (2014): July 2014
Publisher : Indonesian Pediatric Society

Background Neonatal mortality remains a major concern indeveloping countries. Identifying potential risk factors is importantin order to decrease the neonatal mortality rate. In MoewardiHospital, Surakarta, the risk factors for neonatal mortality havenot been assessed.Objective To evaluate potential risk factors of n eonatalmortality.Methods We reviewed medical records of all neonates hospitalizedin the neonatal intensive care unit (NICU) at Dr. MoewardiHospital from January to December 2011. Analyzed variables weresex, birth weight, gestational age, maternal age, place of delivery,mode of delivery, and sepsis. Data were analyzed by Chi square andbinary logistic regression with 95% confidence intervals (CI).Results Out of841 neonates, the mortality rate was 212 (25.2%).Univariate logistic regression revealed that the significant riskfactors for neonatal mortality were preterm (OR 4.41 ; 95%CI4.24 to 4.57; P=0.0001) , low bir th weight (OR 4.30; 95%CI4.13 to 4.47; P=0.0001), sepsis (OR 2.99; 95%CI 2.81 to 3.17;P=0.0001), maternal age 2:35 years (OR 1.53; 95%CI 1.37 to1.70), and non-spontaneous delivery (OR 1.67; 95%CI 1.50 to1.84). Further multivariate regression analysis revealed that thesignificant risk factors were preterm (OR 2.2 7; 95%CI 2.05 to 2.48;P=0.0001), low birth weight (OR 2.49; 95%CI 2.27 to 2.71; P=0.0001), and sepsis (OR 2.50; 95%CI 2.30 to 2.69; P= 0.0001).Conclusion The risk factors for neonatal mortality in the NICUare preterm, low birth weight, and sepsis.

Diagnostic value of newborn foot length to predict gestational age Mutia Farah Fawziah; Bambang Soebagyo; Dwi Hidayah
Paediatrica Indonesiana Vol 57 No 4 (2017): July 2017
Publisher : Indonesian Pediatric Society

Background Â Identification of gestational age, especially within 48 hours of birth, is crucial for newborns, as the earlier preterm status is detected, the earlier the child can receive optimal management. Newborn foot length is an anthropometric measurement which is easy to perform, inexpensive, and potentially efficient for predicting gestational age.Objective Â To analyze the diagnostic value of newborn foot length in predicting gestational age.Methods Â This diagnostic study was performed between October 2016 and February 2017 in the High Care Unit of Neonates at Dr. Moewardi General Hospital, Surakarta. A total of 152 newborns were consecutively selected and underwent right foot length measurements before 96 hours of age. The correlation between newborn foot length to classify as full term and gestational age was analyzed with Spearmanâ€™s correlation test because of non-normal data distribution. The cut-off point of newborn foot length was calculated by receiver operating characteristic (ROC) curve and diagnostic values of newborn foot length were analyzed by 2 x 2 table with SPSS 21.0 software.Results There were no significant differences between male and female newborns in terms of gestational age, birth weight, choronological age, and newborn foot length (P>0.05). Newborn foot length and gestational age had a significant correlation (r=0.53; P=0.000). The optimal cut-off newborn foot length to predict full term status was 7.1 cm. Newborn foot length below 7.1 cm had sensitivity 75%, specificity 98%, positive predictive value 94.3%, negative predictive value 90.6%, positive likelihood ratio 40.5, negative likelihood ratio 0.25, and post-test probability 94.29%, to predict preterm status in newborns.Conclusion Â Newborn foot length can be used to predict gestational age, especially for the purpose of differentiating between preterm and full term newborns.

TNF-? as a predictive factor of pulmonary hypertension in children with Down syndrome with and without congenital heart disease Latifah Rahmi Hariyanti; Sri Lilijanti Widjaja; Dwi Hidayah
Paediatrica Indonesiana Vol 62 No 1 (2022): January 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.1.2022.61-5

Background Down syndrome (DS) is a chromosomal disorder due to trisomy 21 that may involve congenital heart disease (CHD). Pulmonary hypertension (PH) may be present in DS with and without CHD. TNF-Î± is a cytokine involved in the pathogenesis of inflammation in PH. Objective To determine the association between TNF-Î± and the risk of PH in children with DS with and without congenital heart disease. Methods This observational study was conducted in DS children aged two months to five years who visited the outpatient clinic of a regional referral hospital in Indonesia. Subjects underwent echocardiography and were classified into four groups (CHD-PH, CHD-no PH, no CHD-PH, no CHD-no PH). Serum TNF-Î± was measured in all subjects. We used the ANOVA test to compare mean TNF-Î± between the groups and to determine the optimal TNF-Î± cut-off point. We compared the risk of PH in subjects with TNF-Î± above and below the cut-off point. Results We included 36 DS children in this study. Mean TNF-Î± in the CHD-PH, CHD-no PH, no CHD-PH, and no CHD-no PH groups was 2,564.44 (SD 177.00) pg/mL, 2,112.89 (SD 382.00) pg/mL, 2,211.56 (SD 330.70) pg/mL, and 1,118.89 (SD 1056.65) pg/mL, respectively (p<0.001). The optimal TNF-Î± cut-off point was 2,318 pg/mL. DS children with TNF-Î± â‰¥2,318 pg/mL had a higher risk of CHD (RR=2.6; 95%CI 1.17 to 5.78; p=0.008) and PH (RR=3.5; 95%CI 1.43 to 8.60; p=0.001). Conclusions DS children with CHD accompanied by PH have significantly higher TNF-Î± levels than those without PH and those without CHD. In children with DS, an elevated TNF-Î± level (â‰¥2,318 pg/mL) is associated with a higher risk of CHD and PH.

The Efficacy of Melatonin in Neonatal Sepsis with Respiratory Distress: A Randomized Controlled Study Hidayah, Dwi; Nur Irfani Agita
Journal of Maternal and Child Health Vol. 9 No. 5 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2024.09.05.03

Background: Neonatal sepsis is a significant condition worldwide, contributing to high morbidity and mortality, especially in developing countries such as Indonesia. Neonatal sepsis can rapidly progress to respiratory distress. Melatonin, an effective antioxidant and free radical scavenger, may be an adjuvant therapy. This study aimed to evaluate the efficacy of melatonin in neonatal sepsis with respiratory distress. Subjects and Method: A double-blind randomized controlled study was conducted on 42 neonatal sepsis with respiratory distress diagnosed with clinical and laboratory criteria. The subjects were randomly allocated into treatment and control groups, receiving a single dose of oral melatonin 20 mg and a placebo, respectively. The dependent variables were improvement of suplementation in oxygenation and ventilator, outcome, and hospital length of stay. The independent variables was suplementation melatonin The oxygen supplementation and ventilation support were measured at baseline and 72 hours after therapy. We analyzed all data with SPSS 25 using independent t test and determined the significance level at p < 0.050. Results: Seven of the 21 subjects in the treatment group experienced decreased oxygen supplementation and ventilation support, which was statistically significant (p = 0.009). While the outcome for both groups was the same proportion, it was statistically not significant (p = 1.000). Conclusion: Melatonin administration significantly decreased oxygen supplementation and ventilation support.

Platelet lymphocyte ratio (PLR), neutrophil lymphocyte ratio (NLR), and diastolic dysfunction as neonatal sepsis mortality predictors in preterm neonates Tampy, Safitri Tia; Hidayah, Dwi; Lilijanti, Sri
Paediatrica Indonesiana Vol. 65 No. 3 (2025): May 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.3.2025.216-23

Background Neonatal sepsis is a significant challenge in neonatal care, particularly among preterm neonates who are highly vulnerable due to their underdeveloped immune systems. Traditional markers for predicting the outcomes of neonatal sepsis, such as procalcitonin and C-reactive protein, are not always available all across places. Objective To evaluate the predictive value of platelet lymphocyte ratio (PLR), neutrophil lymphocyte ratio (NLR), and diastolic dysfunction for neonatal sepsis mortality in preterm neonates. Methods A prospective cohort study was conducted in 42 preterm neonates with neonatal sepsis admitted to Dr. Moewardi Hospital. The PLR and NLR were collected at two time points: the first blood specimen was drawn within the first 24 hours of life and the second was collected 72 hours later. Diastolic function was assessed by echocardiography performed within 48–72 hours after the diagnosis of sepsis. Mortality during treatment was recorded as the dependent variable. The relationships among these variables were analyzed with bivariate and multivariate analyses, and the significance level was set at P<0.05. Results Of 42 subjects, 57.1% died. Increased NLR and diastolic dysfunction were significantly associated with an increased risk of mortality (OR=3.64; P=0.049 and OR=25.0; P<0.001, respectively), while PLR was not. Multivariate analysis revealed that diastolic dysfunction remain a significant independent predictor of mortality (adjusted OR=28.9;P=0.001), whereas NLR did not maintain statistical significance (P=0.093). Conclusion Diastolic dysfunction was an independent predictor of mortality in preterm neonatal sepsis. The NLR and PLR did not associate with mortality in preterm neonatal sepsis. Rigorous monitoring of cardiovascular function is crucial in the management of neonatal sepsis.

Hubungan Kadar Malondialdehid dengan Usia Kehamilan pada Bayi Kurang Bulan Hidayah, Dwi; Suryani, Fitri Ika; Rachma, Ulfa Puspita
Sari Pediatri Vol 25, No 5 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp25.5.2024.292-6

Latar belakang. Selama beberapa dekade terakhir, angka kelahiran kurang meningkat di seluruh dunia. Bayi baru lahir, terutama Bayi Kurang Bulan sangat rentan terhadap stres oksidatif karena ketidakseimbangan antara peningkatan produksi Reactive Oxygen Species dan kurangnya kemampuan antioksidan. Adanya cedera oksidatif dapat dilacak dengan pengukuran penanda, malondialdehid hasil dari peroksidasi lipid.Tujuan. Untuk menilai hubungan kadar malondialdehid dengan usia kehamilan, berat lahir, dan asfiksia pada Bayi Kurang Bulan Metode. Penelitian cross-sectional dilakukan pada Bayi Kurang Bulan (Usia Kehamilan 28 - < 37 minggu) yang lahir di Rumah Sakit Umum Daerah Dr. Moewardi pada bulan Mei - November 2021. Teknik pengambilan sampel dilakukan secara consecutive. Variabel bebas adalah kadar malondialdehid, variabel terikat adalah Usia Kehamilan, Berat Lahir, dan asfiksia. Data dianalisis secara statistik dengan uji Kolmogorov-Smirnov, dan nilai p<0,05 dianggap signifikan. Hasil. Didapatkan 42 subjek sebagian besar Usia Kehamilan 28 – < 34 minggu 25 subjek (59,52%) dan 17 subjek (40,48%) ?34 – 37 minggu. Rerata kadar malondialdehid adalah 49,9 nmol / mL. Tidak ada hubungan signifikan kadar malondialdehid dengan Usia Kehamilan [p = 0,301; IK95% = (-2,93) – 9,27], BL [p = 0,867; IK95% = (-11,19) – 9,50] dan asfiksia [(p= 0,168), IK95% = (-10,87) – 1,95].Kesimpulan. Kadar malondialdehid pada Bayi Kurang Bulan tidak berhubungan dengan Usia Kehamilan, Berat Lahir, dan asfiksia.

Pengaruh Perawatan Paliatif Terhadap Peningkatan Kualitas Hidup Pasien Anak dengan Penyakit Jantung Bawaan Sianotik Pratomo, Satrio; Artiko, Bagus; Hidayah, Dwi
Sari Pediatri Vol 26, No 1 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.1.2024.23-9

Latar belakang. Penyakit jantung bawaan sianotik merupakan kelainan jantung yang didapatkan sejak lahir dengan gejala yang bervariasi dari ringan hingga berat. Anak dengan penyakit jantung bawaan membutuhkan perawatan paliatif selain penanganan medis dari tenaga medis profesional. Perawatan Paliatif tersebut memerlukan pengembangan sehingga dapat meningkatkan kualitas hidup anak dengan penyakit jantung bawaan sianotik. Tujuan. Mengetahui pengaruh perawatan paliatif terhadap peningkatan kualitas hidup pada pasien anak dengan penyakit jantung bawaan sianotik. Metode. Pasien anak dengan penyakit jantung bawaan sianotik usia dua hingga kurang dari 18 tahun yang berobat di bagian kardiologi anak Rumah Sakit Umum Daerah Dr. Moewardi. Desain penelitian adalah uji acak terkontrol. Subjek penelitian dibagi menjadi dua grup dengan cara matching dan didapatkan grup kontrol dan intervensi yang masing-masing mendapat perawatan paliatif selama tiga bulan. Penilaian kualitas hidup subjek sebelum dan sesudah perlakuan menggunakan kuosioner PedsQL kardiologi.Hasil. Sejumlah 40 subjek dibagi menjadi kelompok intervensi (20) dan kelompok kontrol (20). Sebanyak 11 pasien dalam kelompok usia 2-4 tahun di grup intervensi memiliki penurunan nilai PedsQL dari rerata 73,9 menjadi 63,2 yang menunjukkan adanya peningkatan kualitas hidup dengan hasil uji statistik pair t test p<0,001 (P<0,05). Pada kelompok usia 5-7 tahun di grup intervensi, terdapat 6 pasien dengan penurunan nilai PedsQL dari rerata 77,5 menjadi 63,4 dengan hasil uji statistik p<0,001 (P<0,05). Sebanyak 3 pasien pada kelompok usia 8 hingga kurang dari 18 tahun di grup intervensi menunjukkan penurunan hasil nilai PedsQL dari rerata 82,8 menjadi 72,7 dengan hasil uji statistik p<0,001 (P<0,05). Hasil uji statistik tiap kelompok usia menunjukkan nilai yang bermakna dengan signifikansi p<0,001.Kesimpulan. Perawatan paliatif dapat meningkatkan kualitas hidup anak dengan penyakit jantung bawaan sianotik usia dua hingga kurang dari 18 tahun di Rumah Sakit Umum Daerah Dr. Moewardi, Surakarta.

Perbedaan Perubahan Kadar Hormon Tiroid pada Bayi Kurang Bulan melalui Pemeriksaan Fungsi Tiroid Serial Al Khusna, Nandia Permata Rahma; Hidayah, Dwi; Giri Moelyo, Annang
Sari Pediatri Vol 26, No 2 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.2.2024.85-90

Latar belakang. Hipotiroid kongenital merupakan gangguan hormon yang terjadi pada bayi baru lahir dimana ditemukan kadar hormon tiroid yang rendah. Pada bayi kurang bulan dan berat lahir rendah dapat mengalami hipotiroksinemia tanpa disertai peningkatan thyroid stimulating hormone. Hal ini bersifat sementara dan akan meningkat seiring pertambahan usia. Tujuan. Menilai perbedaan perubahan kadar hormon tiroid pada bayi kurang bulan melalui pemeriksaan fungsi tiroid serial serta faktor risiko yang berhubungan dengan hal tersebut.Metode. Kohort prospektif dengan melakukan pemeriksaan TSH dan FT4 serial pada BKB di NICU dan HCU Neonatus RSUD Dr. Moewardi bulan Oktober 2022 hingga Januari 2023. Pengambilan sampel dilakukan pada BKB dengan usia kehamilan < 32 minggu dan 32 s/d <37 minggu pada usia 48-72 jam dan 2 minggu. Hasil pengamatan dideskripsikan dengan mean±SD, analisis data dengan SPSS 22 dan dinyatakan signifikan apabila uji menghasilkan p?0,05.Hasil. Didapatkan nilai TSH dan FT4 yang semakin turun pada usia 48-72 jam dan 2 minggu pada kelompok usia kehamilan <32 minggu (TSH p= 0,221; FT4 p=0,008) dan 32 s/d < 37 minggu (TSH p=0,037; FT4 p=0,013). Faktor yang berpengaruh adalah berat badan lahir bayi dimana ditemukan perbedaan signifikan pada berat bayi lahir sangat rendah (p=0,021).Kesimpulan. Bayi prematur, terutama dengan berat lahir sangat rendah, cenderung mengalami hipotiroksemia prematur. Pemeriksaan fungsi tiroid secara berkala sangat penting untuk memantau perkembangan bayi dan mencegah komplikasi jangka panjang.

Co-Authors . Ardiningsih Abdul Aziz Al Khusna, Nandia Permata Rahma Annang Giri Moelyo Arie Kusumawardani Artiko, Bagus Bambang Soebagyo Dio Dara Virgiansari Djaswadi Dasuki Endang Sutisna Sulaeman Endang Sutisna Sulaeman Harsono Salimo Latifah Rahmi Hariyanti Leli Saptawati Lilijanti, Sri Mutia Farah Fawziah Nugraha, Sandi Nugroho, Irfan Dzakir Nuniek Setyo Wardani Nur Irfani Agita Nurrachmat Mulianto Osdatilla Esa Putri Prasetyadi Mawardi Pratomo, Satrio Pristiawan Endraputra Rachma, Ulfa Puspita Rinawati Rohsiswatmo Sri Lilijanti Widjaja Suci Widhiati Suryani, Fitri Ika Tampy, Safitri Tia Widiretnani, Septin Yulidar Hafidh Yulidar Hafidh

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