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All Journal Sari Pediatri Paediatrica Indonesiana Indonesian Journal of Medicine Journal of Maternal and Child Health Jurnal Keperawatan dan Kesehatan Jurnal Ners
Dwi Hidayah
Department Of Child Health, Sebelas Maret University Medical School/Dr. Moewardi Hospital
Health Professions Medicine & Pharmacology Nursing Public Health

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The Association between Hypothermia during Emergency Room Admission and Newborn Mortality at Dr. Moewardi Hospital Hidayah, Dwi; Rohsiswatmo, Rinawati; Hafidh, Yulidar
Journal of Maternal and Child Health Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2023.08.04.06

Abstract

Background: Hypothermia in newborns continues to be a significant issue and a leading cause of morbidity and mortality. The incidence of hypothermia in referral newborns is still high during hospital admission. Subjects and Method: This is a prospective cohort study conducted at Dr. Moewardi Hospital. Data collection was carried out on January 1, 2015, until March 31, 2015, for referred newborns. The dependent variable was mortality and the independent variables included gestational age, birth weight, sepsis, severe respiratory distress, and temperature at the time of admission at the ER. The chi-square test and logistic regression were used to analyze the data, with a cut-off value of p<0.05 cut off and a confidence interval of 95%. Results: There were 56 newborn referrals, with 60.7% incidence of hypothermia and 19.6% inci­dence with mortality. From the chi-square analysis, the variable of gestational age and weight did not meet the requirements of multivariate analysis (p> 0.25). The multivariate logistic regression analysis revealed a non-significant association between severe respiratory distress and mortality in referred newborns (OR= 5.25; 95% CI= 0.89 to 30.82; p= 0.066). After performing multivariate logistic regression analysis to obtain controlled ORs, there was a significant relationship between newborn referrals mortality and temperature at the time of ER admission (OR= 8.75; 95% CI= 1.07 to 3.26; p= 0.047) and sepsis (OR= 6.25; 95% CI= 150 to 28.69; p= 0.012) with mortality of referred newborns. Conclusion: The incidence of hypothermic referred newborns is high. Hypothermia during admission at the ER and sepsis are both associated with increased mortality in referred newborns. Keywords: newborns, hypothermia, mortality. Correspondence:Dwi Hidayah. Department of Child Health, Faculty of Medicine, Sebelas Maret University and Dr. Moewardi General Hospital, Jalan Kolonel Sutarto No.132, Surakarta 57126, Indonesia. Mobile: 08122623728 Email: dwihidayah_dr2020@staff.uns.ac.id
Red-cell distribution width and immature to total ratio as predictors of sepsis mortality in preterm neonates Aziz, Abdul; Hidayah, Dwi; Widiretnani,  Septin
Paediatrica Indonesiana Vol. 65 No. 6 (2025): November 2025
Publisher : Indonesian Pediatric Society

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Abstract

Background Preterm neonates are susceptible to various complications and may require invasive procedures that increase the risk of sepsis, which is the third leading cause of mortality in children. Routine laboratory results, such as red-cell distribution width (RDW) and immature to total neutrophil (I/T) ratio, may be useful as predictors of mortality in neonatal sepsis patients. These laboratory markers have undergone limited testing as mortality predictors in preterm neonates with sepsis. Objective To analyze the predictive ability of RDW and I/T ratio on sepsis mortality in preterm neonates. Methods This prospective cohort study included 42 preterm neonates (gestational age 28-36 weeks + 6 days), with birth weight appropriate to gestational age. The diagnosis of sepsis was established based on the high probable sepsis (HPS) and probable sepsis (PRS) criteria scores. RDW and I/T ratio values were obtained at the time of the sepsis diagnosis. Neonatal mortality was defined as death occurring within the first 28 days of life. Receiver operating characteristic (ROC) curve was used to analyze for associations between mortality and the laboratory markers. Results The median RDW in preterm neonates who died was 16.5% (range 14.0-32.7%). This was relatively similar to the median RDW value in preterm neonates who lived (16.25%; range 14.6-34.3%). ROC curve analysis revealed an area under curve (AUC) of 0.541 (95%CI 0.359 to-0.722; P=0.656). The median I/T ratio in preterm neonates who died was 0.13 (range 0.03-0.22), which was similar to the median I/T ratio in preterm neonates who lived (0.15; range 0.11-8.20). The AUC value was 0.387 (95%CI 0.214 to -0.559; P=0.213). Conclusion The RDW and I/T ratio values cannot be used as predictors of sepsis mortality in preterm neonates.
Maternal Atopy Diathesis on The Newborn’s Skin Acidity and Hydration Osdatilla Esa Putri; Suci Widhiati; Prasetyadi Mawardi; Arie Kusumawardani; Nurrachmat Mulianto; Dwi Hidayah; Pristiawan Endraputra
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.50222

Abstract

Background: Atopic diathesis, a hereditary predisposition to allergic disorders such as atopic dermatitis, asthma, and allergic rhinitis, is more strongly transmitted maternally. Maternal atopy may influence neonatal skin barrier development, but evidence on its effect on neonatal skin pH and hydration is limited. Methods: This cross-sectional study was conducted at Dr. Moewardi General Hospital, Surakarta, Indonesia, between March–April 2025. Neonates (28–41 weeks gestation), <24 hours old, and delivered by cesarean section were included. Skin pH was measured on the volar forearm and axilla using a calibrated pH meter, and hydration (water and oil content) was assessed with a Skin Tester. Maternal atopy diathesis was classified by the Erlangen Atopy Score (EAS). Results: Twenty-nine neonates were enrolled, comprising 12 with and 17 without maternal atopy. No significant association was found between maternal atopy and neonatal hydration (water: p = 0.460; oil: p = 0.997) or skin pH (p = 0.876). Conclusion: Maternal atopy diathesis was not associated with neonatal skin pH or hydration in the first 24 hours of life. Early neonatal skin physiology appears to be influenced more by intrinsic maturation than maternal atopic status. Longitudinal studies are needed to assess potential delayed effects.
Co-Authors . Ardiningsih Abdul Aziz Al Khusna, Nandia Permata Rahma Annang Giri Moelyo Arie Kusumawardani Artiko, Bagus Bambang Soebagyo Dio Dara Virgiansari Djaswadi Dasuki Endang Sutisna Sulaeman Endang Sutisna Sulaeman Harsono Salimo Latifah Rahmi Hariyanti Leli Saptawati Lilijanti, Sri Mutia Farah Fawziah Nugraha, Sandi Nugroho, Irfan Dzakir Nuniek Setyo Wardani Nur Irfani Agita Nurrachmat Mulianto Osdatilla Esa Putri Prasetyadi Mawardi Pratomo, Satrio Pristiawan Endraputra Rachma, Ulfa Puspita Rinawati Rohsiswatmo Sri Lilijanti Widjaja Suci Widhiati Suryani, Fitri Ika Tampy, Safitri Tia Widiretnani,  Septin Yulidar Hafidh Yulidar Hafidh