Dwi Hidayah
Faculty of Medicine, Sebelas Maret University

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Pengaruh Perawatan Paliatif Terhadap Peningkatan Kualitas Hidup Pasien Anak dengan Penyakit Jantung Bawaan Sianotik Pratomo, Satrio; Artiko, Bagus; Hidayah, Dwi
Sari Pediatri Vol 26, No 1 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.1.2024.23-9

Abstract

Latar belakang. Penyakit jantung bawaan sianotik merupakan kelainan jantung yang didapatkan sejak lahir dengan gejala yang bervariasi dari ringan hingga berat. Anak dengan penyakit jantung bawaan membutuhkan perawatan paliatif selain penanganan medis dari tenaga medis profesional. Perawatan Paliatif tersebut memerlukan pengembangan sehingga dapat meningkatkan kualitas hidup anak dengan penyakit jantung bawaan sianotik. Tujuan. Mengetahui pengaruh perawatan paliatif terhadap peningkatan kualitas hidup pada pasien anak dengan penyakit jantung bawaan sianotik. Metode. Pasien anak dengan penyakit jantung bawaan sianotik usia dua hingga kurang dari 18 tahun yang berobat di bagian kardiologi anak Rumah Sakit Umum Daerah Dr. Moewardi. Desain penelitian adalah uji acak terkontrol. Subjek penelitian dibagi menjadi dua grup dengan cara matching dan didapatkan grup kontrol dan intervensi yang masing-masing mendapat perawatan paliatif selama tiga bulan. Penilaian kualitas hidup subjek sebelum dan sesudah perlakuan menggunakan kuosioner PedsQL kardiologi.Hasil. Sejumlah 40 subjek dibagi menjadi kelompok intervensi (20) dan kelompok kontrol (20). Sebanyak 11 pasien dalam kelompok usia 2-4 tahun di grup intervensi memiliki penurunan nilai PedsQL dari rerata 73,9 menjadi 63,2 yang menunjukkan adanya peningkatan kualitas hidup dengan hasil uji statistik pair t test p<0,001 (P<0,05). Pada kelompok usia 5-7 tahun di grup intervensi, terdapat 6 pasien dengan penurunan nilai PedsQL dari rerata 77,5 menjadi 63,4 dengan hasil uji statistik p<0,001 (P<0,05). Sebanyak 3 pasien pada kelompok usia 8 hingga kurang dari 18 tahun di grup intervensi menunjukkan penurunan hasil nilai PedsQL dari rerata 82,8 menjadi 72,7 dengan hasil uji statistik p<0,001 (P<0,05). Hasil uji statistik tiap kelompok usia menunjukkan nilai yang bermakna dengan signifikansi p<0,001.Kesimpulan. Perawatan paliatif dapat meningkatkan kualitas hidup anak dengan penyakit jantung bawaan sianotik usia dua hingga kurang dari 18 tahun di Rumah Sakit Umum Daerah Dr. Moewardi, Surakarta.
Perbedaan Perubahan Kadar Hormon Tiroid pada Bayi Kurang Bulan melalui Pemeriksaan Fungsi Tiroid Serial Al Khusna, Nandia Permata Rahma; Hidayah, Dwi; Giri Moelyo, Annang
Sari Pediatri Vol 26, No 2 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.2.2024.85-90

Abstract

Latar belakang. Hipotiroid kongenital merupakan gangguan hormon yang terjadi pada bayi baru lahir dimana ditemukan kadar hormon tiroid yang rendah. Pada bayi kurang bulan dan berat lahir rendah dapat mengalami hipotiroksinemia tanpa disertai peningkatan thyroid stimulating hormone. Hal ini bersifat sementara dan akan meningkat seiring pertambahan usia. Tujuan. Menilai perbedaan perubahan kadar hormon tiroid pada bayi kurang bulan melalui pemeriksaan fungsi tiroid serial serta faktor risiko yang berhubungan dengan hal tersebut.Metode. Kohort prospektif dengan melakukan pemeriksaan TSH dan FT4 serial pada BKB di NICU dan HCU Neonatus RSUD Dr. Moewardi bulan Oktober 2022 hingga Januari 2023. Pengambilan sampel dilakukan pada BKB dengan usia kehamilan < 32 minggu dan 32 s/d <37 minggu pada usia 48-72 jam dan 2 minggu. Hasil pengamatan dideskripsikan dengan mean±SD, analisis data dengan SPSS 22 dan dinyatakan signifikan apabila uji menghasilkan p?0,05.Hasil. Didapatkan nilai TSH dan FT4 yang semakin turun pada usia 48-72 jam dan 2 minggu pada kelompok usia kehamilan <32 minggu (TSH p= 0,221; FT4 p=0,008) dan 32 s/d < 37 minggu (TSH p=0,037; FT4 p=0,013). Faktor yang berpengaruh adalah berat badan lahir bayi dimana ditemukan perbedaan signifikan pada berat bayi lahir sangat rendah (p=0,021).Kesimpulan. Bayi prematur, terutama dengan berat lahir sangat rendah, cenderung mengalami hipotiroksemia prematur. Pemeriksaan fungsi tiroid secara berkala sangat penting untuk memantau perkembangan bayi dan mencegah komplikasi jangka panjang.
The Association between Hypothermia during Emergency Room Admission and Newborn Mortality at Dr. Moewardi Hospital Hidayah, Dwi; Rohsiswatmo, Rinawati; Hafidh, Yulidar
Journal of Maternal and Child Health Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2023.08.04.06

Abstract

Background: Hypothermia in newborns continues to be a significant issue and a leading cause of morbidity and mortality. The incidence of hypothermia in referral newborns is still high during hospital admission. Subjects and Method: This is a prospective cohort study conducted at Dr. Moewardi Hospital. Data collection was carried out on January 1, 2015, until March 31, 2015, for referred newborns. The dependent variable was mortality and the independent variables included gestational age, birth weight, sepsis, severe respiratory distress, and temperature at the time of admission at the ER. The chi-square test and logistic regression were used to analyze the data, with a cut-off value of p<0.05 cut off and a confidence interval of 95%. Results: There were 56 newborn referrals, with 60.7% incidence of hypothermia and 19.6% inci­dence with mortality. From the chi-square analysis, the variable of gestational age and weight did not meet the requirements of multivariate analysis (p> 0.25). The multivariate logistic regression analysis revealed a non-significant association between severe respiratory distress and mortality in referred newborns (OR= 5.25; 95% CI= 0.89 to 30.82; p= 0.066). After performing multivariate logistic regression analysis to obtain controlled ORs, there was a significant relationship between newborn referrals mortality and temperature at the time of ER admission (OR= 8.75; 95% CI= 1.07 to 3.26; p= 0.047) and sepsis (OR= 6.25; 95% CI= 150 to 28.69; p= 0.012) with mortality of referred newborns. Conclusion: The incidence of hypothermic referred newborns is high. Hypothermia during admission at the ER and sepsis are both associated with increased mortality in referred newborns. Keywords: newborns, hypothermia, mortality. Correspondence:Dwi Hidayah. Department of Child Health, Faculty of Medicine, Sebelas Maret University and Dr. Moewardi General Hospital, Jalan Kolonel Sutarto No.132, Surakarta 57126, Indonesia. Mobile: 08122623728 Email: dwihidayah_dr2020@staff.uns.ac.id
The RELATIONSHIP BETWEEN MATERNAL AGE AND INTRAUTERINE GROWTH RESTRICTION (IUGR) AT DR. MOEWARDI GENERAL HOSPITAL, SURAKARTA Nabiilah, Khusniyatin Dwi; Hidayah, Dwi; Candrarukmi, Dewinda
Jurnal Kesehatan Karya Husada Vol 13 No 4 (2024): Jurnal Kesehatan Karya Husada
Publisher : POLITEKNIK KESEHATAN KARYA HUSDA YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36577/jkkh.v13i4.785

Abstract

Background. Intrauterine Growth Restriction (IUGR) is a fetal growth disorder that significantly impacts neonatal morbidity and mortality, with a high incidence, especially in developing countries. Maternal age is known to be a major risk factor associated with IUGR, therefore, research on the relationship between gestational age and IUGR is crucial to support more effective prevention and treatment efforts in Indonesia. The aim of this study was to determine the relationship between maternal age and IUGR at Dr. Moewardi Regional General Hospital. Methods. This study employed a cross-sectional approach. Sixty-seven pregnant women, selected based on inclusion and exclusion criteria, whose deliveries took place at Dr. Moewardi Regional Hospital between January and December 2024, participated in this study. Secondary data were obtained from medical records and then analyzed using chi-square and logistic regression tests. The Result of 67 subjects, 35 (52.2%) delivered babies with IUGR and 32 (47.8%) non-IUGR[3]. Mothers with risk age had 14.286 times higher odds of delivering babies with IUGR compared to non-risk age (OR 14.286; 95% CI 4.397–46.413; p=0.000). Risk interpregnancy interval also showed significant association with IUGR (OR 12.632; 95% CI 2.606–61.222; p=0.000). Parity, nutritional status, and comorbidities did not show significant association with IUGR. Conclusion: Maternal age is significantly related to IUGR incidence. Pregnant women with risk age require more intensive antenatal monitoring to detect fetal growth disorders early.
Red-cell distribution width and immature to total ratio as predictors of sepsis mortality in preterm neonates Aziz, Abdul; Hidayah, Dwi; Widiretnani,  Septin
Paediatrica Indonesiana Vol. 65 No. 6 (2025): November 2025
Publisher : Indonesian Pediatric Society

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Abstract

Background Preterm neonates are susceptible to various complications and may require invasive procedures that increase the risk of sepsis, which is the third leading cause of mortality in children. Routine laboratory results, such as red-cell distribution width (RDW) and immature to total neutrophil (I/T) ratio, may be useful as predictors of mortality in neonatal sepsis patients. These laboratory markers have undergone limited testing as mortality predictors in preterm neonates with sepsis. Objective To analyze the predictive ability of RDW and I/T ratio on sepsis mortality in preterm neonates. Methods This prospective cohort study included 42 preterm neonates (gestational age 28-36 weeks + 6 days), with birth weight appropriate to gestational age. The diagnosis of sepsis was established based on the high probable sepsis (HPS) and probable sepsis (PRS) criteria scores. RDW and I/T ratio values were obtained at the time of the sepsis diagnosis. Neonatal mortality was defined as death occurring within the first 28 days of life. Receiver operating characteristic (ROC) curve was used to analyze for associations between mortality and the laboratory markers. Results The median RDW in preterm neonates who died was 16.5% (range 14.0-32.7%). This was relatively similar to the median RDW value in preterm neonates who lived (16.25%; range 14.6-34.3%). ROC curve analysis revealed an area under curve (AUC) of 0.541 (95%CI 0.359 to-0.722; P=0.656). The median I/T ratio in preterm neonates who died was 0.13 (range 0.03-0.22), which was similar to the median I/T ratio in preterm neonates who lived (0.15; range 0.11-8.20). The AUC value was 0.387 (95%CI 0.214 to -0.559; P=0.213). Conclusion The RDW and I/T ratio values cannot be used as predictors of sepsis mortality in preterm neonates.