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All Journal Current Biochemistry Iqtishaduna : Jurnal Ilmiah Mahasiswa Hukum Ekonomi Syariah JURNAL ILMIAH SAINS TEKNOLOGI DAN INFORMASI
Rini Novita
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Energy Environmental Science Law, Crime, Criminology & Criminal Justice

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Anti-inflammatory Activity of Temulawak Nanocurcuminoid Coated with Palmitic Acid in The Sprague Dawley Rat Rini Novita; Laksmi Ambarsari; Syamsul Falah; Popi Asri Kurniatin; Waras Nurcholis; Latifah K Darusman
Current Biochemistry Vol. 2 No. 2 (2015)
Publisher : IPB University

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Abstract

Temulawak or Curcuma xanthorrhiza Roxb, is usually used as traditional medicine (herbal medicine) that has antioxidant, anticancer, antihyperglycemic, anti-inflammatory, hepatoprotective and gastroprotective properties. The main components contained in temulawak responsible for its efficacy as a medicine are xantorhizol and curcuminoid. Curcuminoid has drawbacks, which are difficult to absorb and very quickly metabolized by the body, so that limit its bioavailability. The use of solid lipid nanoparticle carrier system (SLN) in form of palmitic acid, is known to improve the bioavailability of curcuminoid. This study aims to find the effective dose of nanocurcuminoid coated with palmitic acid that can be used as an anti-inflammatory agent. The methods used in this study, include the production of nanocurcuminoid with homogenization and ultrasonication methods, determination of particle size, polydispersity index, entrapment efficiency and anti-inflammatory activity test through rat feet edema. Nanocurcuminoid obtained in this study was 561.53 nm in size, with polydispersity index 0.309 and concentrations of curcuminoid absorbed and entrapment efficiency were 0.61±0.031 mg/mL, 58.93±3.021%, respectively. Anti-inflammatory activity of nanocurcuminoid through treated Sprague Dawley rats, showed that there were no significant difference compared with the positive control, curcuminoid extracts and empty nanoparticle. These results indicate that nanocurcuminoid with 175, 200 and 250 mg/kg.bw in doses, has greater anti-inflammatory activity (31.70%) compared to the other treatments.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS ANDROID PADA MATA PELAJARAN DASAR-DASAR DESAIN KOMUNIKASI VISUAL KELAS X DKV DI SMK NEGERI 1 PASAMAN Silwi Uswatun Hasanah; Irsyadunas; Rini Novita
JURNAL ILMIAH SAINS TEKNOLOGI DAN INFORMASI Vol. 2 No. 2 (2024): April
Publisher : CV. ALIM'SPUBLISHING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jiti.v2i2.704

Abstract

The aim of this research is to develop valid and practical learning media for the basics of visual communication design. The process of learning the basics of visual communication design at SMKN 1 Pasaman is not optimal, this is caused by several problems, namely the availability of learning media only in the form of printed books that students borrow from the school library. This causes students to not understand the learning material and be less motivated to study and cause low student grades. Based on the data obtained, the students' KKM completion score was only 53%. This research uses the Research and Development (R&D) research and development method with the ADDIE model which consists of 5 stages, namely Analysis, Design, Development, Implementation and Evaluation at each stage. This research involved 36 class X DKV students who took part in learning the basics of visual communication design. The results of this research are Android-based learning software that can be used as a complement to the learning process, especially in the basics of visual communication design subjects. Data collection techniques are in the form of observations and questionnaires, while data collection instruments are in the form of validity questionnaires and practicality questionnaires. The data analysis technique uses a Likert scale with the Aiken formula. The results of this research show that the validity value of the media is an average of 81.53% in the "Very Valid" category, while the validity of the material is an average of 93.85% in the "Very Practical" category and the teacher's practicality assessment is an average of 81.77% in the "Practical" category. " while students' practicality assessment averaged 83.3% in the "Practical" category.
KAJIAN HUKUM MENGENAI PENGELOLAAN LIMBAH RUMAH TANGGA B3 BERDASARKAN PERMEN LHK NOMOR 9 TAHUN 2024 Ade Yuliany Siahaan; Lestari V. Sinaga; Rini Novita
Iqtishaduna: Jurnal Ilmiah Mahasiswa Hukum Ekonomi Syariah Vol 6 No 4 (2025): Juli
Publisher : Jurusan Hukum Ekonomi Syariah Fakultas Syariah dan Hukum Uin Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/iqtishaduna.v6i4.61696

Abstract

Abstrak Limbah rumah tangga yang mengandung Bahan Berbahaya dan Beracun (B3) dapat menimbulkan risiko besar terhadap kesehatan manusia serta kelestarian lingkungan. Sebagai langkah antisipatif, pemerintah mengeluarkan Permen LHK Nomor 9 Tahun 2024 yang mengatur tata kelola limbah B3 rumah tangga. Penelitian ini bertujuan menelaah aspek hukum, tingkat efektivitas, serta kendala penerapan peraturan tersebut. Metode penelitian yang dipakai adalah penelitian hukum normatif dengan pendekatan perundang-undangan dan konseptual. Bahan hukum dihimpun dari regulasi, literatur akademik, serta penelitian sebelumnya, kemudian dianalisis secara kualitatif. Hasil kajian menunjukkan bahwa Permen LHK No. 9/2024 telah menyediakan landasan yuridis yang cukup jelas mengenai kewajiban pemerintah, masyarakat, dan pelaku usaha dalam pengelolaan limbah B3 rumah tangga. Akan tetapi, penerapannya masih menghadapi hambatan berupa rendahnya partisipasi masyarakat, kurangnya fasilitas pendukung, dan lemahnya mekanisme pengawasan. Oleh karena itu, diperlukan peningkatan edukasi publik, penyediaan sarana yang memadai, serta penguatan sinergi antar-pemangku kepentingan agar regulasi ini dapat berjalan efektif. Kata Kunci: Hukum lingkungan, pengelolaan limbah B3, Permen LHK No. 9/2024.   Abstract Household waste containing hazardous and toxic materials (B3) poses significant risks to human health and environmental sustainability. To address this issue, the government enacted Minister of Environment and Forestry Regulation (Permen LHK) No. 9 of 2024, which governs the management of household B3 waste. This study aims to examine the legal framework, assess the effectiveness, and identify the challenges in implementing the regulation. The research employs a normative legal method using a statutory and conceptual approach. Legal materials were collected from legislation, academic literature, and previous studies, and then analyzed qualitatively. The findings indicate that Permen LHK No. 9/2024 provides a clear legal foundation regarding the obligations of government, society, and businesses in managing household B3 waste. However, its implementation still encounters obstacles, such as low public participation, limited supporting facilities, and weak enforcement mechanisms. Therefore, enhanced public education, adequate infrastructure provision, and stronger stakeholder collaboration are required to ensure the effective application of the regulation. Keywords: environmental law, household hazardous waste, Permen LHK No. 9/2024.
Co-Authors Ade Yuliany Siahaan Irsyadunas LAKSMI AMBARSARI Latifah K Darusman Lestari V. Sinaga Silwi Uswatun Hasanah Syamsul Falah Waras Nurcholis