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Anti-inflammatory Activity of Temulawak Nanocurcuminoid Coated with Palmitic Acid in The Sprague Dawley Rat Rini Novita; Laksmi Ambarsari; Syamsul Falah; Popi Asri Kurniatin; Waras Nurcholis; Latifah K Darusman
Current Biochemistry Vol. 2 No. 2 (2015)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Temulawak or Curcuma xanthorrhiza Roxb, is usually used as traditional medicine (herbal medicine) that has antioxidant, anticancer, antihyperglycemic, anti-inflammatory, hepatoprotective and gastroprotective properties. The main components contained in temulawak responsible for its efficacy as a medicine are xantorhizol and curcuminoid. Curcuminoid has drawbacks, which are difficult to absorb and very quickly metabolized by the body, so that limit its bioavailability. The use of solid lipid nanoparticle carrier system (SLN) in form of palmitic acid, is known to improve the bioavailability of curcuminoid. This study aims to find the effective dose of nanocurcuminoid coated with palmitic acid that can be used as an anti-inflammatory agent. The methods used in this study, include the production of nanocurcuminoid with homogenization and ultrasonication methods, determination of particle size, polydispersity index, entrapment efficiency and anti-inflammatory activity test through rat feet edema. Nanocurcuminoid obtained in this study was 561.53 nm in size, with polydispersity index 0.309 and concentrations of curcuminoid absorbed and entrapment efficiency were 0.61±0.031 mg/mL, 58.93±3.021%, respectively. Anti-inflammatory activity of nanocurcuminoid through treated Sprague Dawley rats, showed that there were no significant difference compared with the positive control, curcuminoid extracts and empty nanoparticle. These results indicate that nanocurcuminoid with 175, 200 and 250 mg/kg.bw in doses, has greater anti-inflammatory activity (31.70%) compared to the other treatments.
KAJIAN HUKUM MENGENAI PENGELOLAAN LIMBAH RUMAH TANGGA B3 BERDASARKAN PERMEN LHK NOMOR 9 TAHUN 2024 Ade Yuliany Siahaan; Lestari V. Sinaga; Rini Novita
Iqtishaduna: Jurnal Ilmiah Mahasiswa Hukum Ekonomi Syariah Vol 6 No 4 (2025): Juli
Publisher : Jurusan Hukum Ekonomi Syariah Fakultas Syariah dan Hukum Uin Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/iqtishaduna.v6i4.61696

Abstract

Abstrak Limbah rumah tangga yang mengandung Bahan Berbahaya dan Beracun (B3) dapat menimbulkan risiko besar terhadap kesehatan manusia serta kelestarian lingkungan. Sebagai langkah antisipatif, pemerintah mengeluarkan Permen LHK Nomor 9 Tahun 2024 yang mengatur tata kelola limbah B3 rumah tangga. Penelitian ini bertujuan menelaah aspek hukum, tingkat efektivitas, serta kendala penerapan peraturan tersebut. Metode penelitian yang dipakai adalah penelitian hukum normatif dengan pendekatan perundang-undangan dan konseptual. Bahan hukum dihimpun dari regulasi, literatur akademik, serta penelitian sebelumnya, kemudian dianalisis secara kualitatif. Hasil kajian menunjukkan bahwa Permen LHK No. 9/2024 telah menyediakan landasan yuridis yang cukup jelas mengenai kewajiban pemerintah, masyarakat, dan pelaku usaha dalam pengelolaan limbah B3 rumah tangga. Akan tetapi, penerapannya masih menghadapi hambatan berupa rendahnya partisipasi masyarakat, kurangnya fasilitas pendukung, dan lemahnya mekanisme pengawasan. Oleh karena itu, diperlukan peningkatan edukasi publik, penyediaan sarana yang memadai, serta penguatan sinergi antar-pemangku kepentingan agar regulasi ini dapat berjalan efektif. Kata Kunci: Hukum lingkungan, pengelolaan limbah B3, Permen LHK No. 9/2024.   Abstract Household waste containing hazardous and toxic materials (B3) poses significant risks to human health and environmental sustainability. To address this issue, the government enacted Minister of Environment and Forestry Regulation (Permen LHK) No. 9 of 2024, which governs the management of household B3 waste. This study aims to examine the legal framework, assess the effectiveness, and identify the challenges in implementing the regulation. The research employs a normative legal method using a statutory and conceptual approach. Legal materials were collected from legislation, academic literature, and previous studies, and then analyzed qualitatively. The findings indicate that Permen LHK No. 9/2024 provides a clear legal foundation regarding the obligations of government, society, and businesses in managing household B3 waste. However, its implementation still encounters obstacles, such as low public participation, limited supporting facilities, and weak enforcement mechanisms. Therefore, enhanced public education, adequate infrastructure provision, and stronger stakeholder collaboration are required to ensure the effective application of the regulation. Keywords: environmental law, household hazardous waste, Permen LHK No. 9/2024.
Pengembangan Learning Management System dengan Fitur Gamifikasi untuk Pembelajaran Informatika di SMK Negeri 1 Koto Baru Maideshinta, Tri Kurnia; Faiza Rini; Rini Novita
Jurnal Informatika Polinema Vol. 12 No. 2 (2026): Vol. 12 No. 2 (2026)
Publisher : UPT P2M State Polytechnic of Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33795/jip.v12i2.8491

Abstract

Pendidikan berperan penting dalam membentuk sumber daya manusia berkualitas, dan pemanfaatan teknologi informasi menjadi kebutuhan mendesak untuk meningkatkan mutu pembelajaran. Di SMK Negeri 1 Koto Baru, keterbatasan waktu, rendahnya motivasi belajar, serta metode penyampaian materi yang kurang interaktif menjadi kendala dalam mencapai hasil optimal pada mata pelajaran informatika. Integrasi fitur gamifikasi seperti leaderboard, badge, dan tugas dalam bentuk quest atau tantangan diharapkan meningkatkan keterlibatan siswa, menciptakan suasana belajar interaktif, serta membantu guru mengelola pembelajaran secara efektif meski waktu terbatas. Penelitian ini menggunakan metode Research and Development (R&D) dengan model ADDIE (Analysis, Design, Development, Implementation, Evaluation). Analisis dilakukan untuk mengidentifikasi kebutuhan, dilanjutkan perancangan modul konten, evaluasi, dan integrasi fitur gamifikasi. Produk diuji melalui validasi ahli dan uji praktikalitas melibatkan guru dan siswa kelas X. Hasil penelitian menunjukkan LMS dengan gamifikasi mendapatkan kategori sangat valid (91%) untuk uji validasi media dan kategori valid (89%) untuk uji validasi materi. Untuk uji praktikalitas guru dan siswa memperoleh nilai rata-rata 92% dengan kategori sangat praktis. Dengan demikian, pengembangan LMS berbasis Moodle dengan fitur gamifikasi menjadi solusi inovatif untuk pembelajaran informatika yang lebih menarik, efektif, dan efisien, terutama pada keterbatasan waktu di SMK Negeri 1 Koto Baru.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS AUGMENTED REALITY (AR) PADA MATERI CAMERA MOVEMENT KELAS XI DKV DI SMK NEGERI 2 PADANG PANJANG Aulia Janatun Nissa; Heri Mulyono; Rini Novita
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 11 No. 01 (2026): Volume 11 No. 01 Maret 2026 Published
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v11i01.41359

Abstract

The rapid development of digital technology has driven the need for innovative, interactive, and contextual learning media, particularly in vocational education. Observations conducted in Grade XI Visual Communication Design (DKV) at SMK Negeri 2 Padang Panjang revealed that students experienced difficulties in understanding camera movement material due to the dominant use of lecture-based methods and limited learning media. This condition resulted in low learning motivation and insufficient conceptual understanding. This study aims to develop Augmented Reality (AR)-based learning media for camera movement material and to determine the validity and practicality of the developed media. The research employed a Research and Development (R&D) method using the ADDIE model, which consists of analysis, design, development, implementation, and evaluation stages. The research subjects included two media experts, two subject-matter experts, two teachers, and 25 Grade XI DKV students. Data were collected through observation, interviews, and validity and practicality questionnaires, while data analysis used a quantitative descriptive approach. The results indicated that the AR-based learning media achieved a very high level of validity, with percentages of 92.82% from media experts and 92.29% from material experts. Furthermore, the practicality level was categorized as very practical based on teacher assessments (94.27%) and student assessments (87.67%). Therefore, AR-based learning media are feasible to be used as an interactive learning alternative to enhance students’ conceptual understanding and learning motivation in camera movement material.
Local Wisdom of Relativity as Living Law in Personal Data Protection: Reconstruction of Islamic Law Ethics against Intimate Digital Crimes in Indonesia Ismed Batubara; Rini Novita; Dhani DS Hasibuan; Hengky Syahyunan; Indra Fajar
International Journal of Law, Crime and Justice Vol. 3 No. 1 (2026): March : International Journal of Law, Crime and Justice
Publisher : Asosiasi Penelitian dan Pengajar Ilmu Hukum Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijlcj.v3i1.924

Abstract

This study aims to examine the influence of local wisdom as a living law on personal data protection behavior, as well as assess the role of Islamic law ethics and digital literacy in the context of intimate digital crime in Indonesia. The background of this research is based on the increasing cases of misuse of personal data in the digital space that have not been fully responded to effectively through formal legal approaches. The method used a quantitative approach with a correlational explanatory design. Data were obtained through the distribution of a questionnaire based on the Likert scale to 150 respondents who were selected purposively, then analyzed using descriptive statistics, Pearson correlation, and simple linear regression. The results showed that local wisdom of alwasliyahan had a positive and significant influence on personal data protection behavior (β = 0.42; p < 0.05). Islamic legal ethics serve as a mediating variable that strengthens the relationship, while digital literacy provides a positive influence at a moderate level. These findings show that the internalization religious and cultural values plays an important role in shaping individual awareness and behavior in protecting personal data in the digital era. The conclusion of this study emphasizes that local wisdom can function effectively as a living law in supporting the protection of personal data. This research makes theoretical contribution the development of the study of Islamic law and the sociology of law, as well as practical implications for policy formulation that integrates formal regulations, cultural values, and digital literacy.
Rancang Bangun Aplikasi Absensi Online di SMK Menggunakan Framework Laravel Herisvan Hendra; Haris Kurniawan; Rini Novita; Ami Anggraini Samudra; Widya Islamiah Sibarani; Kuntum Khaira Ummah; Laura Anggraini
MASALIQ Vol 6 No 1 (2026): JANUARI
Publisher : Lembaga Yasin AlSys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/masaliq.v6i1.8904

Abstract

Although attendance management systems have been widely discussed in previous research, studies that specifically examine the implementation of web-based attendance systems using the Laravel framework in vocational high schools remain limited. This study aimed to develop an integrated online attendance system based on the Laravel framework to overcome the limitations of manual attendance methods. A quantitative approach was employed using the Software Development Life Cycle (SDLC) waterfall model and a Model–View–Controller (MVC) architecture. The system was designed for two types of users, namely administrators and participants, with system requirements data collected through direct observation of manual attendance processes to identify sources of inefficiency. The results indicate that the developed system was able to reduce recording errors by up to 95%, increase attendance process efficiency by 40%, and shorten recording time from an average of 12 seconds to 4 seconds per transaction. In addition, data integration across modules achieved 98% consistency with no detected inconsistencies. These findings contribute to the development of web-based information system theory and broaden understanding of Laravel framework implementation in the context of vocational education. The study concludes that adopting a Laravel-based attendance system is an important component of digital transformation in vocational high schools and recommends the implementation of integrated digital attendance solutions as a strategic step toward modernizing attendance management. The implications of this research include theoretical contributions to the literature on web-based system development and practical implications for educational institutions seeking to modernize attendance processes, while also opening opportunities for further studies on biometric integration and mobile application development.
PENGEMBANGAN SISTEM INFORMASI PRAKTIK KERJA LAPANGAN BERBASIS WEB DI SMK KARTIKA 1-2 PADANG Aryani Carissa Puteri; Rini Novita; Rahayu Trisetyowati Untari
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 11 No. 02 (2026): Volume 11 No. 2, Juni 2026 Publish
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v11i02.48455

Abstract

Field Work Practice (PKL) is one of the important programs in Vocational High Schools (SMK) to equip students with real experience in the industrial world. However, the implementation of PKL at SMK Kartika 1-2 Padang still faces several obstacles, such as manual data management, attendance and activity journals that are prone to manipulation, and the process of collecting reports that is time-consuming and costly. To overcome these problems, this study aims to develop a web-based PKL information system that can facilitate the management of PKL activities effectively and efficiently. This study uses the System Development Life Cycle (SDLC) method with the Waterfall model, which includes the stages of planning, analysis, design, implementation, and system testing. The system design was developed using the Laravel framework with MySQL database support. System testing was carried out in two stages, namely the alpha test which includes Whitebox Testing and Blackbox Testing, and the beta test involving experts and users to assess the quality and level of practicality of the system. The results of the study indicate that the PKL information system that was built has functioned as expected. The alpha test demonstrated that all system components functioned smoothly without significant issues, while the beta test yielded highly satisfactory results, with an average rating of 96.98% from experts and 90.89% from users. Based on these results, this web-based PKL information system is considered highly practical and capable of supporting the management of PKL activities at SMK Kartika 1-2 Padang more effectively, efficiently, and transparently.