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PERBEDAAN EFEK SEDUHAN KULIT DAN JUS BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP KADAR TRIGLISERIDA SERUM TIKUS Sprague dawley DISLIPIDEMIA I Dewa Gede Angga Pramana; Martha Ardiaria; Ahmad Syauqy
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.333 KB) | DOI: 10.14710/dmj.v5i4.14461

Abstract

Latar Belakang : Dislipidemia merupakan abnormalitas profil lipid dalam serum, salah satunya adalah peningkatan kadar trigliserida serum. Buah naga merah (Hylocereus polyrhizus) terbukti memperbaiki profil lipid karena adanya kandungan fenolat dan flavonoid. Kulit buah naga merah mengandung kandungan gizi seperti karbohidrat, lemak, protein, serat dan senyawa betasianin.Tujuan : Mengetahui perbedaan efek pemberian seduhan kulit dan jus daging buah naga merah terhadap kadar trigliserida serum tikus Sprague dawley dislipidemia.Metode : Jenis penelitian adalah true experimental dengan pre and post test with control group design. Sampel adalah tikus jantan Sprague dawley usia 10 minggu, diinduksi dislipidemia dengan telur puyuh dan asam kolat. Pada kelompok K(-) diberi pakan standar, kelompok K(+) diberi pakan tinggi kolesterol, kelompok P1 diberi seduhan kulit buah naga merah dan kelompok P2 diberi jus buah naga merah. Kadar trigliserida serum diperiksa dengan metode CHOD-PAP dan GPO-PAP. Data kemudian dianalisis menggunakan uji paired t test dan one way ANOVA.Hasil : Terdapat perbedaan bermakna sebelum dan setelah intervensi pada kelompok K(-), K(+), P1 dan P2. Pemberian seduhan kulit selama 14 hari dapat menurunkan kadar trigliserida sebesar 53,61 mg/dl (SD= 4,06) sedangkan jus buah naga merah dapat menurunkan kadar trigliserida sebesar 36,99 mg/dl (SD= 8,14). Setelah intervensi terdapat perbedaan rerata kadar trigliserida antar kelompok p=0,000 kecuali K(-) dengan seduhan kulit p=1,000.Simpulan : Pemberian seduhan kulit buah naga merah dan jus daging buah naga merah selama 14 hari dengan dosis 9,08 g/200 gbb tikus dan 1,53 g/200 gbb tikus dapat menurunkan kadar trigliserida serum masing-masing sebesar 53,61 mg/dl (SD= 4,06) dan 36,99 mg/dl (SD= 8,14) pada tikus Sprague dawley dislipidemia.
PERBANDINGAN PH SALIVA SETELAH KONSUMSI BUAH NANAS DAN BUAH BELIMBING Ahmad Syauqy; Mirna Iskandar
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 10 No. 1 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.816 KB) | DOI: 10.22437/jmj.v10i1.13201

Abstract

Latar Belakang: Masalah rongga mulut di Indonesia yang terbanyak adalah terkait karies gigi dan penyakit periodontal. Salah satu faktor yang mempengaruhi timbulnya penyakit tersebut adalah pH saliva. Stimulus mekanik dan kimiawi dari makanan adalah salah satu faktor yang mempengaruhi pH saliva. Cuci mulut dengan mengkonsumsi buah adalah salah satu cara menjaga pH saliva agar dalam kondisi optimum dalam mencegah terjadinya penyakit gigi. Dari penelitian sebelumnya diketahui bahwa buah nanas dan buah belimbing efektif dalam meningkatkan laju aliran saliva. Tujuan: Penelitian ini bertujuan untuk membandingkan pH saliva setelah mengkonsumsi buah nanas dan belimbing. Metode : Penelitian ini adalah penelitian experimental dengan menggunakan pretest and postest group design. Populasi yang digunakan adalah mahasiswa Fakultas Kedokteran FKIK UNJA angkatan 2017 dan 2018. Pengambilan sampel dilakukan dengan metode purposive sampling sebanyak 36 orang yang dibagi menjadi dua kelompok yaitu kelompok perlakuan mengkonsumsi buah nanas dan buah belimbing. Hasil pemeriksaan pH saliva kedua kelompok dianalisis menggunakan program komputer. Hasil: Uji statistik menunjukkan tidak terdapat perbedaan yang signifikan antara kelompok buah nanas dengan kelompok buah belimbing dalam meningkatkan pH saliva dengan nilai p 0,855. Simpulan: Konsumsi buah nanas dan belimbing dapat meningkatkan pH saliva, namun tidak terdapat perbedaan yang signifikan antara kelompok buah nanas dengan kelompok buah belimbing. Kata kunci :  pH, Saliva, Nanas, Belimbing
HUBUNGAN EKSPRESI 8OH2DG SEBAGAI PENANDA STRES OKSIDATIF KERUSAKAN DNA DENGAN KEJADIAN PREEKLAMPSIA DAN LUARAN NEONATAL Citra Maharani; Herlambang Herlambang; Anggelia Puspasari; Ahmad Syauqy; Huntari Harahap; Betty Marlina
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 10 No. 4 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (557.583 KB) | DOI: 10.22437/jmj.v10i4.21102

Abstract

Background: Hypoxic conditions in preeclampsia cause oxidative stress in the placenta. Oxidative stress triggers endothelial dysfunction resulting in changes in placental parenchyma and vasculature, turn leads to clinical manifestations in maternal and neonatal. Previous studies reported that preeclampsia placental tissue increased the expression of the oxidative stress marker 8OH2dG.Objective: This study aimed to observe the expression of the marker 8OH2dG on the incidence ofpreeclampsia and its association with neonatal outcome.Methods: This study design was case-control, a number of 44 pregnant women participated in this study. The case group was preeclampsia women based on American College of Obstetricians and Gynecologist (ACOG) 2013 criteria and normotensive women as control group. The immunohistochemical was perform in placental tissue for expression of 8OH2dG in trophoblast nuclei. The results were positive when the trophoblast cell nuclei were stained ≥5% with moderate and strong intensity; and negative if stained weakly <5%. Bivariate analysis was performed to determine the association of 8OH2dG expression with preeclampsia and neonatal outcome.Results: This study reported the frequency of trophoblast nuclei with 8OH2dG positive staining was higher in the preeclampsia group than the control group. Expression of 8OH2dG positive staining also increased the risk of low birth weight and asphyxia.Conclusion: The results of this study indicate that the marker 8OH2dG is associated with preeclampsia and adversely neonatal outcome.Keywords: 8OH2dG, preeclampsia, oxidative stress, neonatal outcome
MANAGEMENT OF SCABIES IN ISLAMIC BOARDING SCHOOLS: DEVELOPMENT OF EARLY DETECTION CADRES WITHIN THE TAHTUL YAMAN COMMUNITY HEALTH CENTER AREA, JAMBI CITY, 2024 Hanina; Fitriyanti, Fitriyanti; Lipinwati; Hasna Dewi; Ahmad Syauqy; Attiya Istarini; Ivo Amrina Rasyada
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

ABSTRACT Scabies is a skin disease that is often found in Indonesia caused by Sarcoptes scabei. The prevalence of scabies in Islamic boarding school environments in Jambi is around 4.9%. Sandra Widaty et al. from the Faculty of Medicine, University of Indonesia, have developed a Deskab (Early Detection of Scabies) form that can be used by ordinary people (cadres) very easily, and the results are relatively similar to those carried out by medical personnel. The method is to present cadres and resource persons, conduct a pretest, provide scabies material, posttest, and training on how to directly apply the Deskab form by cadres and be assessed by a doctor. There were 18 participants from four Islamic boarding schools. The majority of participants were male (67%) and adults (19-59 years) (67%). The average pretest and posttest score was 79.64 (80%) and 83.78 (83%). The average score for the Deskab results is 95.12 (95%), and all cadres have a score above 79. All cadres are declared to have passed and are expected to be able to carry out early detection screening on santri so that efforts to control scabies in the work area of the Tahtul Yaman Health Center can be realized as planned. Keywords: scabies, Deskab, cadre, boarding school
The Education of Family Medicine Services Using Artificial Intelligence Video Method for Hypertension Prolanis Patients at Simpang Kawat Health Center. Okta Arizki; Armaidi Darmawan; Ahmad Syauqy; Wahyu Indah Dewi Aurora; Esa Indah Ayudia
Journal of Medical Studies Vol. 5 No. 2 (2025): Journal of Medical Studies (Ongoing Issue)
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v5i2.40517

Abstract

Background: Hypertension management requires effective strategies, with family medicine often playing a neglected role. Objective: This study examines the efficacy of AI-based videos in improving knowledge among Prolanis hypertension patients at Simpang Kawat Health Center. Methods: This quasi-experimental study employed a pre-test post-test control group design. The experimental group (43 Prolanis hypertension patients from Simpang Kawat Health Center) received AI video education, while the control group (39 patients from Talang Bakung Health Center) received traditional slide-based education. Participants were selected via purposive sampling. Results: The majority of patients at Simpang Kawat Health Center were adults (55.8%), female (86%), and had primary education (44.2%). In contrast, most patients at Talang Bakung Health Center were elderly (76.9%), female (100%), and had primary education (74.4%). The knowledge level of hypertensive Prolanis patients at Simpang Kawat Health Center significantly improved after receiving AI-based video education, with the percentage of patients with low knowledge dropping from 88.4% to 41.9%. Similarly, at Talang Bakung Health Center, the standard education method led to an improvement, with the percentage of patients with low knowledge reducing from 87.2% to 60.5%. Conclusion: AI-based educational videos were more effective than traditional methods in enhancing patient knowledge.
Uji Beda Leukosit dan NLR (Neutrophil Lymphocyte-Ratio) terhadap Luaran Pasien Sepsis Rawat ICU (Intensive Care Unit) RSUD Raden Mattaher Jambi 2019 - Oktober 2022 Aidil Rahmat Ilham; Lipinwati, Lipinwati; Ahmad Syauqy; Samsirun Halim; Sotianingsih, Sotianingsih; Ekaputri, Tia Wida
Journal of Medical Studies Vol. 4 No. 1 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i1.31935

Abstract

ABSTRACT Background: Sepsis is a clinical syndrome caused by an overreaction of the body's immune response stimulated by microbes or bacteria inside and outside the body. There is visible organ dysfunction. Of an increase of 2 or more scoresSequential Organ Failure Assessment (SOFA). Early diagnosis and treatment by assessing inflammatory factors such as leukocytes and NLR (Neutrophil-to-lymphocyte ratio). This study aims to determine the difference between leukocyte levels and NLR values based on the outcome of septic patients. Method: This study used an analytic observational cohort method with a retrospective and prospective approach involving 54 research subjects, using consecutive sampling. Sampling was done by calculating leukocyte levels and NLR values at 0, 24, 72, and 144 hours in septic patients. Results: The patients who died for more than 24 hours were 36 patients. The highest average results were measured at 24 hours, with leukocytes 17.48 ± 8.49 and NLR 24.96 ± 22.17. The mean leukocyte and NLR levels were higher in the death group. The analysis found no significant difference between the leukocyte and NLR with the outcomes in septic patients (p >0.05). Conclusion: There was no significant difference between leukocytes and NLR with the outcome of septic patients. Keywords: Biomarkers, Leukocytes, Mortality, NLR, Sepsis   ABSTRAK Latar Belakang: Sepsis adalah suatu sindrom klinik oleh karena reaksi yang berlebihan dari respon imun tubuh yang distimulasi mikroba atau bakteri dari dalam dan luar tubuh. Terdapat disfungsi organ yang terlihat. dari peningkatan 2 atau lebih skor Sequential Organ Failure Assessment (SOFA). Diagnosis dan penanganan lebih awal dengan menilai faktor inflamasi seperti leukosit dan NLR (Neutrophil-to-lymphocyte rasio). Penelitian ini bertujuan untuk mengetahui perbedaan antara kadar leukosit dan nilai NLR berdasarkan luaran pasien sepsis. Metode: Penelitian ini menggunakan metode analitik observasional kohort, dengan pendekatan retrospektif dan prospektif yang melibatkan 54 subjek penelitian, menggunakan teknik consecutive sampling. Pengambilan sampel dilakukan dengan cara menghitung kadar leukosit dan nilai NLR pada jam ke-0, 24, 72, dan 144 pada pasien sepsis. Hasil: Dari 54 sampel, hasil luaran pasien meninggal lebih banyak pada jam 24 sebanyak 36 pasien. Rerata hasil tertinggi pada pada pengukuran jam 24 dengan Leukosit 17,48±8,49 dan NLR 24,96±22,17. Rerata kadar leukosit dan nilai NLR lebih tinggi pada kelompok luaran meninggal. Hasil analisis tidak terdapat perbedaan yang signifikan antara Leukosit dan NLR dengan luaran pasien sepsis (p >0,05). Kesimpulan: Tidak terdapat perbedaan yang signifikan antara Leukosit dan NLR terhadap luaran pasien sepsis. Kata Kunci: Biomarker, Leukosit, Mortalitas, NLR, Sepsis
INTERACTIVE VISUAL EDUCATION TO ENHANCE KNOWLEDGE OF LOW BACK PAIN AMONG THE ELDERLY AND CAREGIVERS AT OLAK KEMANG HEALTH CARE, JAMBI CITY Humaryanto, Humaryanto; Attiya istarini; Lipinwati, Lipinwati; Perkasa, Tengku Arief Buana; Ahmad Syauqy; Hasna Dewi; Fitriyanti; Juanda, Syahreza Hadi; Zikri, Rahmat
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 2 (2025): MEDIC. Medical dedication (In Progress)
Publisher : Universitas Jambi

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Abstract

Low back pain is a common degenerative illness among the elderly, significantly impacting their quality of life and independence. Insufficient understanding of effective management frequently worsens the disease. The objective of this community service program was to enhance comprehension of low back pain among elderly and their caregivers at the Olak Kemang Public Health Centre in Jambi City. The programme consisted of an instructional session with 41 participants utilising a multidisciplinary-developed interactive visual module, accompanied by a practical demonstration of stretching exercises. A pre- and post-test design was used to quantitatively evaluate the alteration in participants' knowledge. The data were examined with the Wilcoxon and Pearson chi-square tests. The findings indicated a statistically significant enhancement in participants' knowledge, with the median score increasing from 60 (range: 30-80) in the pre-test to 85 (range: 50-100) in the post-test (p < 0.001). The number of participants who attained a passing score (≥70%) rose considerably from 19 to 31 (p = 0.007). The interactive visual education program effectively enhances awareness regarding lowback pain among the elderly and their caregivers. This strategy is highly recommended for implementation in other community health programs. Keywords: Low back pain; caregiver; health education; elderly