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All Journal e-Journal Pustaka Kesehatan STOMATOGNATIC- Jurnal Kedokteran Gigi ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) Health Notions Journal of Dentomaxillofacial Science Indonesian Journal of Life Sciences Denta: Jurnal Kedokteran Gigi Odonto dental journal
Erna Sulistyani
Fakultas Kedokteran Gigi Universitas Jember
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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Journal : e-Journal Pustaka Kesehatan

 1 
Kadar Serum Glutamic Oxaloacetic Transaminase (SGOT) pada Tikus Wistar (Rattus norvegicus) Jantan yang Dipapar Stresor Rasa Sakit Electrical Foot Shock selama 28 Hari (The Level of Serum Glutamic Oxaloacetic Transaminase (SGOT) in Male Wistar Rat (Ratt Nur Lely Yaumil Qodriyati; Erna Sulistyani; Budi Yuwono
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

  Stress is a natural reaction that allows the human compelled to face the difficulties. Stimuli that causes stress can be physical and psychological. Physical stressors can occur continuously or sustained, which causes pathological processes in the body. This pathological process may be occur in liver and heart. One of parameter to assess characteristics of tissue can use Serum Glutamic Oxaloacetic transaminase (SGOT). The aim of this study was to prove differences level of SGOT in male Wistar rats (Rattus norvegicus) that exposed and control group were not exposed by pain stressor electrical foot shock for 28 days. Blood sampling was carried out on day 28 in intracardiac then tested the levels of SGOT. Statistical analysis showed that there was no significant change (p≤0,05) between control and treatment group. Liver damage from stressors may be not cause necrosis of liver cells. SGOT was not a single biomarker that was specific and sensitive for the diagnosis of liver disease because SGOT was also found in the heart.   Keywords: electrical foot shock, SGOT, stress
Pengaruh Jus Tomat Segar (Lycopersicon esculentum Mill) terhadapKadar Trigliserida dalam Darah Tikus Wistar Jantan yang Diberi Lipid Peroral (The Effect of Fresh Tomato Juice (Lycopersicon esculentum Mill) to The Triglyceride Levels in The Blood of Male W Riclas Yusuf Punta Wibisono; Happy Harmono; Erna Sulistyani
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Increased levels of lipid which is characterized by increasedlevels of triglycerides until now has not found an effective and efficient. Some sources say there are9-oxo-ODA in tomatoes to cause triglyceride levels in the blood. Purpose : The aim of The Study todetermineeffect of tomatoe juice on blood serum Triglycerides level inmalewistarrat. This experimental study used male wistar rats, and the post test only control group design. Rats were divided into three groups, i.e. negative control group (K-), positif control group (K+), and treatment group (P). K-group was untreated by fresh tomato juice and fed with standart diet only. K+ group was fed with standart and peroral lipid. P group treated with fresh tomato juice and also fed with standart and lipid peroral.Fresh Tomato juice were treated by means of stomach sondation for 14 days. On day the 15th, rats were sacrified and intracardial blood were taken 3-5 ml for examination of lipid profile by enzimatic colorimetric method using an automatic test analizer. Data were analyzed by one way anova followed by LSD test. The conclusion of this study is the average triglyceride levels between the negative control group (K-) and positive control (K +) was not significantly different, and no changes in triglyceride levels in the control group (K +) and the treatmentgroup. Keywords: tomato juice, Triglycerides, 9-oxo-ODA
Kadar Serum Glutamat Piruvat Transaminase (SGPT) pada Tikus Wistar (Rattus norvegicus) Jantan yang Dipapar Stresor Rasa Sakit berupa Electrical Foot Shock selama 28 Hari (The Level of Serum Glutamic Pyrufic Transaminase [SGPT] on a Wistar [Rattus norvegic Hesty Kumala Sari; Roedy Budirahardjo; Erna Sulistyani
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Stress is the body response toward any kind of stressors that can lead to physiological changes in body systems. When it’s stresses, it will secretes stress hormones, such as cortisol, which can lead to elevate gluconeogenesis in liver. The cortisol blood levels increase much greater in rats exposed to 28 days stressors. It will force liver cells to perform continuous gluconeogenesis. These can cause damage to liver cells that can be characterized by increased levels of SGPT (Serum Glutamic Pyruvic transaminase). The aim of the study was to determine the differences in SGPT levels between male Wistar rats that were exposed by electrical foot shock stressors for 28 days and control rats. This was an experimental laboratory with post -test only with control group design, with sixteen rats were divided into two groups; control group and treatment group. The treatment group were exposed by electrical foot shock stressor for 28 days. On 28th day, serum samples were taken for examination of SGPT levels in both samples by kinetic methods . The results of T-test showed that there was no difference in SGPT levels between treatment and control groups. Keywords: electrical foot shock, serum glutamic pyruvic transaminase level.
Daya Hambat Kombinasi Ekstrak Pegagan (Centella asiatica, L.) dan Peppermint terhadap Pertumbuhan Streptococcus mutans Lutfi Lailia Sofidiana; Erna Sulistyani; Pujiana Endah Lestari
Pustaka Kesehatan Vol 10 No 3 (2022): Volume 10 No.3, 2022
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v10i3.25232

Abstract

Pegagan leaves and peppermint leaves contain antibacterial and refreshed breath so that the leaves of both these plants have the potential to be used as a mouthwash to prevent many conditions of the oral cavity including caries. One way to reduce the incidence of caries is to use mouthwash that can inhibit the growth of caries-causing bacteria, namely Streptococcus mutans. The use of chemical mouthwash many side effects. Therefore, it is necessary to innovate natural-based mouthwashes that can inhibit the growth of S. mutans with minimal side effects. This study aimed to proved the antibacterial power of the combination of pegagan leaf extract (Centella asiatica) and peppermint leaf (Mentha piperita) in inhibiting the growth of S. mutans. This study used the disc diffusion methode of 4 treatment groups (5%, 10%, 20% and 40% extract), positive control group (chlorhexidine), and negative control group (sterile akuades). Data were analyzed using Kruskal-Wallis Test and Mann-Whitney test. The combination extract of pegagan (Centella asiatica) and peppermint (Mentha piperita) has an antibacterial effect and can inhibit the growth of S. mutans.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ungu (Graptophyllum pictum (L) Griff) terhadap Pertumbuhan Streptococcus sanguinis Syahrani, Nafila; Kurniawati, Atik; Prihanti, Ayu Mahartini; Sulistyani, Erna; Lestari, Pujiana Endah
Pustaka Kesehatan Vol 12 No 1 (2024): Volume 12 No.1, 2024
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v12i1.42325

Abstract

Streptococcus sanguinis has strong adhesion with salivary pellicles which causes other oral bacteria to attach more and has contribution in causing caries and periodontal disease. S. sanguinis mediated the adhesion of S. mutans to dental pellicle receptors so inhibiting the interaction between S. sanguinis and S. mutans would prevent the risk of dental caries. Purple leaf (Graptophyllum pictum) is one of the medicinal plants or natural ingredients that are useful as antibacterials. The purpose of this study was to examine antibacterial activity of purple leaf extract against S. sanguinis. This experimental laboratory study with a pre-posttest control group design was conducted by dilution method on treatment groups, purple leaf extract with concentrations of 25%, 12.5%, 6.25% and 3.12%. Visual and spectrophotometer examination was observed before and after incubation.The result showed that purple leaf extract with concentrations of 6.25% and 3.12% and control + groups had not turbidity and decreased absorbance value. Furthermore, the One Way Anova parametric statistical test and also Post-Hoc Least Significant Difference showed that there were significant differences between the study groups. The purple leaf extract (Graptophyllum pictum L. Griff) had antibacterial activity against S. sanguinis. The antibacterial test for extracts that are dark in color can be continued using the TVC (Total Viable Count) method to provide a quantitative estimate of the concentration of bacterial cells in the sample in units of CFU/ml.
Co-Authors Adik Wulandari Agustin, Merry Ayu Ayu Ainunnusak Ayuningtyas Andriani, Hilma Annisa Syifa M. Atik Kurniawati, Atik Bilqis P. Safitri Budi Yuwono Dani Agam Rahmadianto Dewi, Leni Rokhma Dwi Prijatmoko Enti Isnarni Enti Isnarni, Enti Futaihana, Hasna' Garaniva Gayuh Setyawan Gayuh Setyawan, Gayuh Hafizh, Cinantya Handayani, Ari T.W. Happy Harmono Hasna' Fakhriyah J. Herniyati Herniyati Herniyati Hesty Kumala Sari Iin Eliana Triwahyuni Khairunnisa, Luthfitah Zahra Leliana S. Devi Leliana Sandra Devi Ade Putri Lisa Miftakhul Janna Lutfi Lailia Sofidiana Mayangsari, Zahra Muchamad Ziyad Afif Nihla Fitriyani Nur Lely Yaumil Qodriyati Perwitasuci, Brigitta Damai Prameswari, Syefira Putri Prihanti, Ayu Mahartini PUDJI ASTUTI Pujiana Endah Lestari Riclas Yusuf Punta Wibisono Rina Sutjiati Rina Sutjiatu Roedy Budirahardjo Rudi Joelijanto Rudy Joealijanto Saikha Adila Azzah Sholehah, Almaratus Sulistyani Sulistyani Swandari, Rindang Syahrani, Nafila Wulandari, Widya Nurfitriastuti Zahreni Hamzah