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All Journal Majalah Kedokteran Bandung Althea Medical Journal Indonesian Journal of Urology Jurnal Kesehatan Andalas Global Medical and Health Communication Jurnal Jamu Indonesia Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Jurnal Integrasi Kesehatan dan Sains Bandung Conference Series : Medical Science Indonesian Journal of Jamu
Yuktiana Kharisma
Department Of Anatomical Pathology, Faculty Of Medicine Universitas Islam Bandung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Journal : Althea Medical Journal

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Maternal Characteristics and Histopathological Features of Placenta Accreta Spectrum in Dr. Hasan Sadikin General Hospital Bandung, Period 2015–2020 Yuktiana Kharisma; Hasrayati Agustina; Sri Suryanti; Birgitta Maria Dewayani; Bethy Suryawati Hernowo
Althea Medical Journal Vol 9, No 1 (2022)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v9n1.2631

Abstract

Background: The placenta accreta spectrum (PAS) incidence has inclined today. The PAS is divided into three histopathological classifications, including accreta, increta, and percreta, associated with maternal, fetal morbidity, and mortality. This study aimed to explore the maternal characteristics and histopathological features in PAS at Dr. Hasan Sadikin General Hospital Bandung.Methods: This descriptive observational study involved 135 cases from January 2015–December 2020 at Dr. Hasan Sadikin General Hospital that met the inclusion criteria. The PAS histopathological classification was evaluated based on maternal characteristics such as age, parity, cesarean section (CS), and miscarriage. Results: The incidence of placenta accreta from 2015 to 2020 was 37.0%, whereas increta was 43.4%, followed by percreta at 19.3%. The maternal age of placenta accreta and increta mainly occurred at the age of 30–34 years with the prevalence of 40% and 46%, respectively, whereas percreta was aged 35–39 yo (27%). Most parities in placenta accreta, increta, percreta were three. Interestingly, 93% of cases had a CS history. Furthermore, the miscarriage history for accreta was 18%, increta 29% and percreta 38%. Conclusion: The highest incidence of PAS in Dr. Hasan Sadikin General Hospital is placenta increta, which mainly occurs at the age of 30–34 years. Almost all PAS patients have a history of CS; however, most of the patients do not have a miscarriage history.
Nuclear Changes Features in Buccal Mucosa Smear of Adult Male Smokers Using Pappaniculou Staining Kharisma, Yuktiana; Indriyanti, Raden Anita; Yuniarti, Lelly; Noormartany, Noormartany; Nur, Ismet Muchtar; Yenolinsky, Yolanda
Althea Medical Journal Vol 12, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n1.3486

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Background: Tobacco smoke contains a combination of chemicals that could be harmful to the buccal mucosa as the first part of the body that has been exposed. Damage to the buccal epithelial cells has the potential to become a malignant lesion. This study aimed to describe changes in the nuclear epithelial of the buccal mucosa using Pappaniculou staining as an indicator of mucosal damage in smokers.Methods: This was a descriptive analytical study, involving adult male participants from Bale Endah District, Bandung Regency, Indonesia aged >35 years, who had smoked for ≥10 years. Buccal mucosa smear was taken, and the features of nuclear epithelial changes were observed per 500 cells, each at 400x magnification with Pappaniculou stain to evaluate the features of micronucleus, broken egg, karyorrhexis, karyolysis. Those who did not smoke were recruited as a control group.Results: Smokers were mostly light active smokers or kretek cigarettes, with a smoking duration of ≥15 years. The frequency of micronucleus (p<0.001), broken eggs (p<0.001), karyorrhexis (p=0.001), karyolysis (p=0.003) in the buccal mucosal epithelial was significantly different between the smoker and non-smoker groups.Conclusions: All epithelial nuclear changes have shown significant differences between smoker and non-smoker groups. Nuclear epithelial features in smoker may be associated with future malignancies, therefore, smoking cessation programs are necessary to substantially reduce tobacco use, thus fostering a healthy lifestyle for everyone.
Co-Authors Aaron Tigor Abdul Hadi Hassan Abdul Hadi Hassan Aldri Frinaldi Andriane, Yuke Armaya Ariyoga Astari P. Riani Astri Kania Astri Kania, Astri Ayu Prasetia Azlia Salsabila Rahadian Putri Bethy Suryawati Hernowo Bethy Suryawati Hernowo Bethy Suryawati Hernowo Birgitta Maria Dewayani Birgitta Maria Dewayani Dewayani, Birgitta Maria Eka Hendryanny Eka Nurhayati Ermina Widiyastuti Fajar Awalia Yulianto Faridza, Muhammad Fasyah Rizki Putri Hasrayati Agustina Hasrayati Agustina Hasrayati Agustina Hernowo, Bethy Suryawaty Herri S. Sastramihardja Hikmatussalam, Gemila Ismet Muchtar Nur Laila Dinda Nadiyah Lelly Yuniarti Maya Tejasari Meike Rachmawati Meta Maulida Damayanti Miranti Kania Dewi Mochamad Firdaus Bhuanaputra Muhammad Alief Abdul ‘Aziiz Muhammad Ilham Halim Nadiyah, Laila Dinda Noormartany Putri Anggraini Aswad Raden Anita Indriyanti Rahmi Fathonah Rahmi Fathonah, Rahmi Raissa Khais Azmi Ratna Damailia Romadhona, Nurul Santoso, Shenny Dianathasari Santun Bhekti Rahimah Sri Suryanti Sri Suryanti Titik Respati Uci Ari Lantika Winni Maharani Yenolinsky, Yolanda Yuniarti Yuniarti Yuniarti Yuniarti