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All Journal Jurnal Sains dan Teknologi Farmasi JOPS (Journal Of Pharmacy and Science) JURNAL EDUCATION AND DEVELOPMENT JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Ipteks Terapan JFIOnline Jurnal Farmasi Higea pendidikan, science, teknologi, dan ekonomi Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Jurnal Kesehatan Terapan JIKA Pharmacon: Jurnal Farmasi Indonesia
Muslim Suardi
Universitas Andalas
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Luaran Klinik Terapi Antivirus pada Pasien Komorbid dan non-Komorbid T2-DM COVID-19 di RSUD Rasidin Muslim Suardi
JURNAL FARMASI DAN MAKANAN Vol 6 No 1 (2022): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i1.3016

Abstract

Patients with comorbidity is vulnerable to being attacked by COVID-19. Diabetes mellitus comorbid patients have experience of higher severity viral infections than those without diabetes mellitus. The objective of the research was to evaluate the impact of Type 2 Diabetes Mellitus (T2-DM) comorbidity and antiviral therapy on the clinical outcome of COVID-19 patients. The study was performed following a cross sectional design from April 2020 to March 2021 at Hospital dr Rasidin Padang. Data were collected retrospectively from the patient's medical record. Treatment and clinical outcomes of patients were analyzed using the Kruskal Wallis, Mann-Withney U Test, Repeated Measured ANOVA, and Friedman Test. Results showed that the respiratory rate on T2-DM comorbid and non-comorbid patients were 20.58±0.25 and 20.15±0.08 times/minutes, respectively (p<0.05). While, oxygen saturation was 97.95±0.16 and 98.38±0.06%, respectively (p<0.05). Patient’s length of stay after the treatment of oseltamivir and favipiravir on non-comorbid COVID-19 patients were 14.76±0.861 and 9.96±0.488 days, respectively (p<0.01). While on comorbid patients were 16.00 ±3.17 and 10.47±0.77, respectively (p<0.01). Comorbidity had a significantly impacted on the patient's respiratory rate and oxygen saturation. The use of oseltamivir and favipiravir had a highly significant different on the LOS of comorbid and non-comorbid patients.
PEMBUATAN DAN KARAKTERISASI TABLET UREA DENGAN METODE KEMPA LANGSUNG Elmi Sariani Hasibuan; Akmal Djamaan; Muslim Suardi
Jurnal Education and Development Vol 11 No 1 (2023): Vol.11 No.1. 2023
Publisher : Institut Pendidikan Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.404 KB) | DOI: 10.37081/ed.v11i1.4525

Abstract

Urea merupakan salah satu pupuk berbasis nitrogen yang paling melimpah dengan proses manufaktur yang berkembang dengan baik dan kemanjurannya dalam meningkatkan ketersediaan nutrisi dan akumulasi senyawa protein dalam tanaman. Salah satu kelemahan penggunaan granul urea sebagai pupuk adalah kelarutannya dalam air yang tinggi dari 119mg/100ml pada 200C. Karena tingginya kelarutan, perkiraan efisiensi penggunaan nitrogen diseluruh dunia hanya 20-35%. Bahan yang digunakan adalah granul urea, dilakukan pemeriksaan bahan baku dan pembuatan tablet ureanya dengan metode kempa langsung, tablet urea yang dihasilkan selanjutnya di evaluasi dan pengujian pelepasan pada media tanah dan lumpur. Dari hasil penelitian diperoleh bahwa tablet urea lebih lama bertahan di media tanah dan lumpur dibandingkan dengan granul urea. Kesimpulan Penggunaan tablet urea lebih efisien dibandingkan granul urea karena dengan merubah bentuk granul urea menjadi tablet urea dapat mengurangi laju kehilangan urea, meminimalkan dampak negatif yang berhubungan dengan penggunaan takaran yang berlebihan dan juga dapat mengurangi dampak pencemaran lingkungan.
Penentuan Titik Akhir Titrasi yang Tepat untuk Penentuan Kadar Amonium Klorida Muslim Suardi
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 2 (2023): Volume 1 Nomor 2 Juni 2023
Publisher : LPPM Universitas Abdurrab

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Abstract

The end point titration is very important to obtain the accurate analysis. No reference was found related with the end point titration of Mohr’s method. In other hand, the quality of drug is important to ensure efficacy and safety. One of requirement is the contain of the drug. Instability of a drug product related with a decreasing in the quality of the drug in term loss of drug efficacy and may be become toxic. Black Cough Syrup is one of famous cough medicine, in Indonesia called Obat Batuk Hitam (OBH). One of the active substances in OBH is ammonium chloride. The determination of titration point in argentometry should be considered appropriately. The study aims were to determine the exact end point of titration and the levels of ammonium chloride in OBH of 3 preparations available in the market and determine the end point titration. NH4Cl levels were determined using the argentometric titration method. The percentage of ammonium chloride in samples A, B and C were 96.84±1.07, 93.57±1.10, and 97.10±1.10%, respectively. Ammonium chloride levels in all samples fulfill the requirements of official pharmacopeia. The titration point was at once the changing of solution color from pale yellow into reddish brown
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN MATOA (Pometia pinnata J.R. Forst. & G. Forst) Islami, Deri; Falakhudin, Khoirul Anam; Suardi, Muslim
Jurnal Ilmu Kesehatan Abdurrab Vol 2 No 1 (2024): Volume 2 Nomor 1 Maret 2024
Publisher : LPPM Universitas Abdurrab

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Abstract

Matoa (Pometia pinnata J.R. Forst. & G. Forst) can be used as traditional medicine. The plant contains secondary metabolite compounds such as flavonoids, tannins, terpenoids and saponins that have the ability to inhibit the mechanism of action of bacteria. The purpose of this study was to determine the antibacterial activity of n-hexane, ethyl acetate and ethanol extracts of Matoa leaves against gram-positive bacteria Staphylococcus aureus and Streptococcus mutans and gram-negative bacteria Escherichia coli and Klebsiella pneumonia at concentrations of 70, 50, 30 and 10% using the disc diffusion method, Ciprofloxacin as a positive control and DMSO as a negative control. Statistical test results on 70% concentration of ethyl acetate extract showed average results on the inhibition diameter of Staphylococcus aureus, Streptococcus mutans, Eschericia coli and Klebsiella pneumenia were 10.63, 13.43, 11.23, and 13.26 mm, respectively. Based on the results of this study, it can be concluded that the n-hexane, ethyl acetate and ethanol extracts of Matoa Leaf (Pometia pinnata J.R. Forst. & G. Forst) have the ability to inhibit the growth of gram-positive bacteria Staphylococcus aureus and Streptococcus mutans and gram negative bacteria Escherichia coli and Klebsiella pneumonia, but in the n-hexane extract of matoa leaves is not able to inhibit the growth of Staphylococcus aureus.
Gelatin Hasil Transformasi Kulit Ikan Patin (Pangasius hypohthalmus) sebagai Gelling Agent dalam Formulasi Gel Piroksikam Suardi, Muslim
Jurnal Ilmu Kesehatan Abdurrab Vol 2 No 1 (2024): Volume 2 Nomor 1 Maret 2024
Publisher : LPPM Universitas Abdurrab

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Abstract

Piroxicam is an effective non-steroidal anti-inflammatory drug, but it has serious side effects orally. The research was conducted to formulate piroxicam in gel dosage form using gelatin transformed from catfish skin (Pangasius hypophthalmus) as a gelling agent. Using this ingredient transformed from pig and cow is unacceptable for certain religious adherents. This study aims were to formulate piroxicam gel and determine the release of piroxicam from gel at various concentrations of 0.75, 0.875, and 1%, while innovator product (F4) was used as a positive control. The evaluations performed were organoleptic, homogeneity, pH, spreadability, and release profile. The release of piroxicam from the gel produced was conducted using a modified paddle-type dissolution device equipped with an eggshell membrane placed on a metal disk. The level of piroxicam dissolved was measured using a UV spectrophotometer at λmax of 356.4 nm. The release kinetics of piroxicam gel formulas F1, F2, F3 and F4 followed zero-order kinetics model. The dissolution efficiency and T90 from formulas F1, F2, F3, and F4 value were highly significant differences (p < 0.01), while the dissolution rate were significant differences (p < 0.05). All of formula fulfill the requirements except spreadability characteristic.
Penyuluhan Kosmetik Aman dan Halal pada Siswa SMA Negeri 2 Siak Hulu Suardi, Muslim; Wahyu Margi Sidoretno; Rambe, Wahyudi; Shinta Lestari, Suci; Pasadena, Helga
JDISTIRA - Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Vol. 5 No. 1 (2025)
Publisher : Yayasan Rahmatan Fidunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jdt.v5i1.1307

Abstract

Peningkatan pemakaian produk kosmetik di kalangan remaja memerlukan perhatian khusus terhadap keamanan dan kehalalan produk yang digunakan. Kurangnya pemahaman mengenai zat berbahaya serta sertifikasi halal dapat berisiko bagi kesehatan dan keyakinan agama mereka. Kegiatan pengabdian kepada masyarakat ini dilakukan melalui penyuluhan interaktif kepada siswa SMA Negeri 2 Siak Hulu guna meningkatkan pengetahuan dan pemahaman mereka terkait kosmetik yang aman dan halal. Evaluasi program dilakukan dengan membandingkan hasil pretest dan posttest menggunakan analisis deskriptif. Hasilnya menunjukkan peningkatan signifikan dalam pemahaman siswa, dengan rata-rata nilai pretest sebesar 65% dan posttest 95%, mengalami peningkatan sebesar 30%. Program ini berhasil memberikan wawasan yang lebih baik kepada siswa, sekaligus mendorong mereka untuk lebih selektif dalam memilih kosmetik yang sesuai dengan prinsip kesehatan dan kehalalan. Temuan ini sekaligus menjadi dasar penting untuk melaksanakan program edukasi berkelanjutan tentang kosmetik yang aman dan halal di kalangan remaja
The Potential UV-B Filter of Gel Preparation Containing Ethanol Extract of Bidara Arab Leaf (Ziziphus spina-christi) Cultivated in Indonesia Mardhiyani, Dini; Aswatul Ulya; Eni Yanti Wulan Desri; Gendis Purno Yudanti; Muslim Suardi; Vonny Kurnia Utama; Kony Putriani; Isna Wardaniati
Pharmacon: Jurnal Farmasi Indonesia Vol. 22 No. 1 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i1.7487

Abstract

Bidara arab leaf (Ziziphus spina-christi) contains flavonoids, saponins, triterpenoids, alkaloids, steroids, and lipids that may act synergistically as natural UV filters. Flavonoids are highlighted for their ability to absorb UVA and UVB light, while other compounds may enhance photoprotection. Previous studies reported that its ethanol extract contains 1.53% flavonoids and exhibits strong antioxidant activity (LC₅₀ = 90.96 ppm). To formulate gel preparations containing Bidara Arab leaf ethanol extract and evaluate their physicochemical properties, sun protection factor (SPF), and photoprotective efficacy against UV-B–induced erythema. The extract was incorporated into gel at concentrations of 2.5% (F1), 5% (F2), and 10% (F3). Physicochemical tests included organoleptic assessment, pH, viscosity, and spreadability. In vitro SPF was determined using UV-Vis spectrophotometry. In vivo testing involved UV-B–irradiated mice, and erythema was scored to assess protection. All gels met standard parameters (pH 5.34–6.51; viscosity 10.352–15.459 cP; spreadability 5.2–5.8 cm). SPF values were 19.26 (F1), 20.22 (F2), and 20.50 (F3), indicating medium UV-B protection. Erythema scores in all extract-treated groups were 0, with erythema areas of 0.50 mm², 0.38 mm², and 0.19 mm², respectively—significantly lower than in the blank gel (3.96 mm²) and untreated control (7.51 mm²) (p<0.01). Bidara arab leaf extract gel (2.5–10%) shows medium SPF protection and effectively prevents UV-B–induced erythema in mice. These findings support its potential as a natural sunscreen agent.
Effectiveness of Mango Leaf Extract (Mangifera indica L) on Healing of Second Level Cut Wound in Male White Mice (Mus musculus) Suhatri, Suhatri; Fidiyani, Dwi; Azzahra, Nia; Suardi, Muslim
JURNAL KESEHATAN TERAPAN Vol 9 No 2 (2022): Jurnal Kesehatan Terapan
Publisher : LPPM Universitas Kader Bangsa Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54816/jk.v9i2.520

Abstract

Mango leaves have several secondary metabolites which have pharmacological effects and may be used to cure cuts or other injuries. The purpose of this study was to determine the effectiveness of the mango leaf extract on wound healing in male white mice. This experimental research was carried out at the Pharmacy Laboratory, Universitas Kader Bangsa and STIK Siti Khodijah, Palembang in July to August 2021. Mango leaves were macerated using 96% ethanol. The extract obtained was prepared into the ointment at concentrations of 10, 20, and 40%. Mango leaf extract ointment, positive, and negative control were each applied twice daily. Wound length was measured using a caliper on days of 2, 4, 6, 8. 10, 12, and 14. The percentage reduction in wound length on day 14 after administration of mango leaf extract ointment 10, 20, and 40% were 14,4±2.07; 17.2±3.70 and 16.4±4.15%; respectively. While the positive control and negative control were 25.4±3.05 and 11.4±1.14%, respectively. There was a significant difference between the administration of the mango leaf extract ointment at concentrations of 20 and 40% compared to the negative control (p<0.05). The mango leaf extract is quite effective in healing Level II cut wounds. Keywords: Bioplacenton, mango leaf extract, wound.
Co-Authors . Khodijah, . Akmal Djamaan Anak Agung Gede Sugianthara Aswatul Ulya Auzal Halim Elmi Sariani Hasibuan Eni Yanti Wulan Desri Erjon, . Erjon, . Falakhudin, Khoirul Anam Fidiyani, Dwi Gendis Purno Yudanti Henny Lucida Islami, Deri Isna Wardaniati Kony Putriani Lailaturrahmi Lailaturrahmi lestari, Suci Shinta Lisa Oktia Sari Mardhiyani, Dini Marissa Sofjan Nia Azzahra Nina Kurniasih Pasadena, Helga Pitricia, Deby Rambe, Wahyudi Raveinal Raveinal Raveinal Raveinal Raveinal, Raveinal Riah Trisnawati Rieke Azhar Rosiana Rizal Salman - Sari, Lisa Oktia Suhatri Suhatri Tuty Taslim vonny kurnia utama Wahyu Margi Sidoretno Yulihasri