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All Journal Jurnal Sains dan Teknologi Farmasi JOPS (Journal Of Pharmacy and Science) JURNAL EDUCATION AND DEVELOPMENT JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Ipteks Terapan JFIOnline Jurnal Farmasi Higea pendidikan, science, teknologi, dan ekonomi Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Jurnal Kesehatan Terapan JIKA Pharmacon: Jurnal Farmasi Indonesia
Muslim Suardi
Universitas Andalas
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Penentuan Titik Akhir Titrasi yang Tepat untuk Penentuan Kadar Amonium Klorida Muslim Suardi
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 2 (2023): Volume 1 Nomor 2 Juni 2023
Publisher : LPPM Universitas Abdurrab

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The end point titration is very important to obtain the accurate analysis. No reference was found related with the end point titration of Mohr’s method. In other hand, the quality of drug is important to ensure efficacy and safety. One of requirement is the contain of the drug. Instability of a drug product related with a decreasing in the quality of the drug in term loss of drug efficacy and may be become toxic. Black Cough Syrup is one of famous cough medicine, in Indonesia called Obat Batuk Hitam (OBH). One of the active substances in OBH is ammonium chloride. The determination of titration point in argentometry should be considered appropriately. The study aims were to determine the exact end point of titration and the levels of ammonium chloride in OBH of 3 preparations available in the market and determine the end point titration. NH4Cl levels were determined using the argentometric titration method. The percentage of ammonium chloride in samples A, B and C were 96.84±1.07, 93.57±1.10, and 97.10±1.10%, respectively. Ammonium chloride levels in all samples fulfill the requirements of official pharmacopeia. The titration point was at once the changing of solution color from pale yellow into reddish brown
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN MATOA (Pometia pinnata J.R. Forst. & G. Forst) Islami, Deri; Falakhudin, Khoirul Anam; Suardi, Muslim
Jurnal Ilmu Kesehatan Abdurrab Vol 2 No 1 (2024): Volume 2 Nomor 1 Maret 2024
Publisher : LPPM Universitas Abdurrab

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Matoa (Pometia pinnata J.R. Forst. & G. Forst) can be used as traditional medicine. The plant contains secondary metabolite compounds such as flavonoids, tannins, terpenoids and saponins that have the ability to inhibit the mechanism of action of bacteria. The purpose of this study was to determine the antibacterial activity of n-hexane, ethyl acetate and ethanol extracts of Matoa leaves against gram-positive bacteria Staphylococcus aureus and Streptococcus mutans and gram-negative bacteria Escherichia coli and Klebsiella pneumonia at concentrations of 70, 50, 30 and 10% using the disc diffusion method, Ciprofloxacin as a positive control and DMSO as a negative control. Statistical test results on 70% concentration of ethyl acetate extract showed average results on the inhibition diameter of Staphylococcus aureus, Streptococcus mutans, Eschericia coli and Klebsiella pneumenia were 10.63, 13.43, 11.23, and 13.26 mm, respectively. Based on the results of this study, it can be concluded that the n-hexane, ethyl acetate and ethanol extracts of Matoa Leaf (Pometia pinnata J.R. Forst. & G. Forst) have the ability to inhibit the growth of gram-positive bacteria Staphylococcus aureus and Streptococcus mutans and gram negative bacteria Escherichia coli and Klebsiella pneumonia, but in the n-hexane extract of matoa leaves is not able to inhibit the growth of Staphylococcus aureus.
Gelatin Hasil Transformasi Kulit Ikan Patin (Pangasius hypohthalmus) sebagai Gelling Agent dalam Formulasi Gel Piroksikam Suardi, Muslim
Jurnal Ilmu Kesehatan Abdurrab Vol 2 No 1 (2024): Volume 2 Nomor 1 Maret 2024
Publisher : LPPM Universitas Abdurrab

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Piroxicam is an effective non-steroidal anti-inflammatory drug, but it has serious side effects orally. The research was conducted to formulate piroxicam in gel dosage form using gelatin transformed from catfish skin (Pangasius hypophthalmus) as a gelling agent. Using this ingredient transformed from pig and cow is unacceptable for certain religious adherents. This study aims were to formulate piroxicam gel and determine the release of piroxicam from gel at various concentrations of 0.75, 0.875, and 1%, while innovator product (F4) was used as a positive control. The evaluations performed were organoleptic, homogeneity, pH, spreadability, and release profile. The release of piroxicam from the gel produced was conducted using a modified paddle-type dissolution device equipped with an eggshell membrane placed on a metal disk. The level of piroxicam dissolved was measured using a UV spectrophotometer at λmax of 356.4 nm. The release kinetics of piroxicam gel formulas F1, F2, F3 and F4 followed zero-order kinetics model. The dissolution efficiency and T90 from formulas F1, F2, F3, and F4 value were highly significant differences (p < 0.01), while the dissolution rate were significant differences (p < 0.05). All of formula fulfill the requirements except spreadability characteristic.
Co-Authors . Khodijah, . Akmal Djamaan Anak Agung Gede Sugianthara Aswatul Ulya Auzal Halim Elmi Sariani Hasibuan Eni Yanti Wulan Desri Erjon, . Erjon, . Falakhudin, Khoirul Anam Fidiyani, Dwi Gendis Purno Yudanti Henny Lucida Islami, Deri Isna Wardaniati Kony Putriani Lailaturrahmi Lailaturrahmi lestari, Suci Shinta Lisa Oktia Sari Mardhiyani, Dini Marissa Sofjan Nia Azzahra Nina Kurniasih Pasadena, Helga Pitricia, Deby Rambe, Wahyudi Raveinal Raveinal Raveinal Raveinal Raveinal, Raveinal Riah Trisnawati Rieke Azhar Rosiana Rizal Salman - Sari, Lisa Oktia Suhatri Suhatri Tuty Taslim vonny kurnia utama Wahyu Margi Sidoretno Yulihasri