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All Journal Jurnal Simetris Jurnal Online Mahasiswa (JOM) Bidang Ilmu Sosial dan Ilmu Politik Jurnal Kedokteran Jurnal Terapan Abdimas SMARTICS Journal Jurnal SOLMA Fokus Ekonomi Jurnal Nasional Pendidikan Teknik Informatika (JANAPATI) Kurawal - Jurnal Teknologi, Informasi dan Industri Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Cermin Dunia Kedokteran Transformasi: Journal of Economics and Business Management
Yudhi Kurniawan
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health Social Sciences Other

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Prokalsitonin dan Sel Darah Putih sebagai Penanda Infeksi pada Anak dengan Ketoasidosis Diabetikum Rochmah, Nur; Faizi, Muhammad; Kurniawan, Yudhi; Choirunisa, Latifatu; Endaryanto, Anang; Soetjipto, Soetjipto
Majalah Kedokteran Indonesia Vol 70 No 12 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.12-2020-291

Abstract

Introduction: Diabetic ketoacidosis (DKA), an acute complication of type 1 (insulin dependent) diabetes mellitus (T1DM), can be precipitated by infection. Procalcitonin (PCT) is an accurate marker of bacteremia, sepsis, and inflammation, however white blood cells (WBC) are still often used by clinicians. We aimed to analyze PCT levels and WBC counts in children with DKA.Methods: A cross-sectional study was conducted in Dr. Soetomo General Hospital, Surabaya, Indonesia, between 2015 and 2019. T1DM and DKA diagnosis was based on the International Society for Pediatric and Adolescent Diabetes. PCT levels and WBC counts were measured in samples from patients with and without DKA, and were compared using the Mann-Whitney test.Results: A total of 41 samples were included, with 15 samples (36.6%) from children with DKA, and 26 (63.4%) from children without DKA. PCT levels and WBC counts were significantly higher in those with DKA (p less than 0.001). The receiver operating characteristic curve analysis of WBC was lower than PCT (0.849 vs. 0.982). PCT had a higher sensitivity and spesificity as an infection marker than WBC (93.3 vs. 86.7; 92.3 vs. 88.5, respectively).Conclusion: PCT is a better infection marker in children with DKA than WBC
Co-Authors Agatha Grace Maharani Sarwono Anang Endaryanto Anis Setyaningrum Arif M. Alhana Anul Habib Azha Satirah Khairunnisa Choirunisa, Latifatu Dedianto Hidajat Ditta, Stefanus Ekadana, Farhan Adriansyah Eva Triani Farhan Adriansyah Ekadana Fransisca Romana Dessyana Kardha Frasiska Wiranti Hasanuddin " Hendro Poerbo Prasetiya Ingrid Valentina Irawan, Paulus Lucky Tirma Krisna, Gathan Fitra Larry Weins Graziano Wengkang Meme Susilowati Merlin Widiya Rezkita Mochamad Adam Harris Anwar Muhammad Faizi, Muhammad Nur Rochmah, Nur Paulus Lucky TI Pertiwi, Kharisma Dharma Rahayu, Aulia Putri Restu Rezkita, Merlin Widiya Rudy Setiawan Salsabiila, Elsa Sandhy Septarian Manoradja Setiyono, Natasha Christita SOETJIPTO . Sukardi Sukardi Syafitri, Renny Diana Wibowo, Ruth Christina Windra Swastika Yuswanto, -