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All Journal Publikasi Pendidikan Jurnal Kebidanan Midwiferia Journal of Issues in Midwifery Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal MID-Z (Midwivery Zigot) Jurnal Ilmiah Kebidanan Jurnal Ners Jurnal Kebidanan Jurnal Medicare Proceeding Mulawarman International Conference on Tropical Public Health
Krisjentha Iffah Agustasari
Universitas Brawijaya
Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Accuracy of Visual Inspection with Acetic Acid for Cervical Lesions: A Systematic Review and Meta-Analysis Faris Regi Riswana; Faris Rega Riswana; Krisjentha Iffah Agustasari; Nabila Khairunisa Azzahra
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Background: Cervical cancer is the most common cancer and a main cause of death among women in low- and middle-income country. A simple screening method using Visual Inspection with Acetic Acid (VIA) has been recommended. However, the diagnostic accuracy of this test varies across populations and clinical contexts. Objective: To evaluate the diagnostic accuracy of VIA compared with the gold standard (histopathology) for detecting precancerous lesions in the cervix. Research Methods: A systematic search was conducted in PubMed, Scopus, and ScienceDirect from 2015 to 2025 following the PRISMA guidelines. A total of 764 studies were identified and only 15 studies were included, with a total sample of 3,237. The risk of bias was assessed using the QUADAS-2. Studies reporting diagnostic outcomes (TP, FP, TN, FN) were included in this review. The data were analysed using a bivariate random-effects model with HSROC curve. Results: The overall analysis showed a pooled sensitivity of 68% (95% CI: 55–80%) and a specificity of 79% (95% CI: 66–88%), indicating moderate diagnostic accuracy across studies. The HSROC curve was positioned toward the upper-left region, reflecting higher specificity and improved model stability. Subgroup analysis revealed that VIA in HIV-negative women demonstrated the best diagnostic performance sensitivity 78%, specificity 85%. When VIA was used as a primary test, it exhibited the most balanced accuracy sensitivity 75%, specificity 80% compared with VIA as a triage test. Conclusion: VIA test demonstrates moderate diagnostic accuracy for detecting cervical precancerous lesions, the best performing in HIV-negative populations, and when used as a primary test.
ACCURACY OF VISUAL INSPECTION WITH ACETIC ACID FOR CERVICAL LESIONS: A SYSTEMATIC REVIEW AND METAANALYSIS  Riswana, Faris Regi; Riswana, Faris Rega; Agustasari, Krisjentha Iffah; Azzahra, Nabila Khairunisa; Rhevytasari, Amanda Fransisca
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Visual inspection with acetic acid (VIA) remains widely used for cervical cancer screening in low- and middle-income countries, despite ongoing concerns regarding its diagnostic accuracy. This study aimed to evaluate the diagnostic performance of VIA for detecting high-grade cervical lesions (CIN2+) compared with histopathology. A systematic search was conducted in PubMed, Scopus, and ScienceDirect (2015–October 2025). Eligible studies provided sufficient data to construct 2×2 tables and were assessed using QUADAS-2. A bivariate random-effects model and HSROC analysis were applied. Thirteen studies were included, with five eligible for quantitative synthesis. Sensitivity ranged from 0.25 to 0.92 and specificity from 0.49 to 0.97, indicating substantial heterogeneity. Risk of bias was generally low to moderate, mainly in patient selection and flow and timing domains. VIA demonstrates moderate accuracy with variability across populations. Although less sensitive than HPV-based screening, VIA remains a pragmatic option in resource-limited settings, particularly within screen-and-treat strategies, with strengthened training and quality assurance required
Co-Authors Anindya Aisha Anis Puji Rahayu Asmika Madjri Azzahra, Nabila Khairunisa Bambang Rahardjo Diadjeng Setya Wardani Dian Kusumaningtyas Dian Kusumaningtyas Faris Rega Riswana Faris Regi Riswana Hapsari, Pradita Tri Indahwati, Lilik Kentri Anggarina Gumanti Lilik Indahwati Mergy Gayatri Nabila Khairunisa Azzahra Nur Aini Retno Hastuti Nur Rohmah Oluwadamilare Akingbade Rahma Dian Hanifarizani Ratna Diana Fransiska Ratna Diana Fransiska Rhevytasari, Amanda Fransisca Riswana, Faris Rega Riswana, Faris Regi Rita Rosita Rizkia, Della Eka Saptadi Yuliarto Suciyanti, Suciyanti Sutrisno Sutrisno Yudhantara, Dearisa Surya