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All Journal IJCCS (Indonesian Journal of Computing and Cybernetics Systems) Jurnal Ilmiah Merpati (Menara Penelitian Akademika Teknologi Informasi) Jurnal Ilmiah Teknik Elektro Komputer dan Informatika (JITEKI) Jurnal Teknologi Informasi dan Ilmu Komputer Jurnal Edukasi dan Penelitian Informatika (JEPIN) KLIK (Kumpulan jurnaL Ilmu Komputer) (e-Journal) Jurnal Komputasi Sebatik Journal of Electronics, Electromedical Engineering, and Medical Informatics Jurnal Teknik Informatika (JUTIF) Journal of Applied Data Sciences Journal of Data Science and Software Engineering Jurnal Informatika Polinema (JIP) Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics
Andi Farmadi
Universitas Lambung Mangkurat
Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Engineering Health Professions Library & Information Science Materials Science & Nanotechnology

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Comparative Analysis of YOLO11 and Mask R-CNN for Automated Glaucoma Detection Fayyadh, Muhammad Naufaldi; Saragih, Triando Hamonangan; Farmadi, Andi; Mazdadi, Muhammad Itqan; Herteno, Rudy; Abdullayev, Vugar
Journal of Electronics, Electromedical Engineering, and Medical Informatics Vol 8 No 1 (2026): January
Publisher : Department of Electromedical Engineering, POLTEKKES KEMENKES SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/jeeemi.v8i1.1266

Abstract

Glaucoma is a progressive optic neuropathy and a major cause of irreversible blindness. Early detection is crucial, yet current practice depends on manual estimation of the vertical Cup-to-Disc Ratio (vCDR), which is subjective and inefficient. Automated fundus image analysis provides scalable solutions but is challenged by low optic cup contrast, dataset variability, and the need for clinically interpretable outcomes. This study aimed to develop and evaluate an automated glaucoma screening pipeline based on optic disc (OD) and optic cup (OC) segmentation, comparing a single-stage model (YOLO11-Segmentation) with a two-stage model (Mask R-CNN with ResNet50-FPN), and validating it using vCDR at a threshold of 0.7. The contributions are fourfold: establishing a benchmark comparison of YOLO11 and Mask R-CNN across three datasets (REFUGE, ORIGA, G1020); linking segmentation accuracy to vCDR-based screening; analyzing precision–recall trade-offs between the models; and providing a reproducible baseline for future studies. The pipeline employed standardized preprocessing (optic nerve head cropping, resizing to 1024×1024, conservative augmentation). YOLO11 was trained for 200 epochs, and Mask R-CNN for 75 epochs. Evaluation metrics included Dice, Intersection over Union (IoU), mean absolute error (MAE), correlation, and classification performance. Results showed that Mask R-CNN achieved higher disc Dice (0.947 in G1020, 0.938 in REFUGE) and recall (0.880 in REFUGE), while YOLO11 attained stronger vCDR correlation (r = 0.900 in ORIGA) and perfect precision (1.000 in G1020). Overall accuracy exceeded 0.92 in REFUGE and G1020. In conclusion, YOLO11 favored conservative screening with fewer false positives, while Mask R-CNN improved sensitivity. These complementary strengths highlight the importance of model selection by screening context and suggest future research on hybrid frameworks and multimodal integration
Co-Authors Abdilah, Muhammad Fariz Fata Abdullayev, Vugar Achmad Rizal Ahdyani, Annisa Salsabila Ahmad Bahroini Ahmad Faris Asy’arie Ahmad Juhdi Ahmad Rusadi Ahmad Rusadi Arrahimi - Universitas Lambung Mangkurat) Ahmad Rusadi Arrahimi - Universitas Lambung Mangkurat) Ahmad Tajali Akhmad Yusuf Ando Hamonangan Saragih Ardiansyah Sukma Wijaya Arif, Nuuruddin Hamid Arifin Hidayat Aris Pratama Azizah, Siti Roziana Bachtiar, Adam Mukharil Bahriddin Abapihi Deni Sutaji Dita Amara Djordi Hadibaya Dodon Turianto Nugrahadi Dwi Kartini Dwi Kartini Dwi Kartini, Dwi Dzira Naufia Jawza Efendi Mohtar Erdi, Muhammad Evi Nadya Prisilla Faisal Murtadho Fathul Hadi Fatma Indriani Fayyadh, Muhammad Naufaldi Fitria Agustina fitria Friska Abadi Ghinaya, Helma Gita Malinda Heru Candra Kartika Heru Kartika Chandra I Gusti Ngurah Antaryama Irwan Budiman Irwan Budiman Jumadi Mabe Parenreng Junaidi, Ridha Fahmi Keswani, Ryan Rhiveldi Khairunnisa Khairunnisa Lisnawati M. Apriannur Miftahul Muhaemen Muhammad Alkaff Muhammad Halim Muhammad Itqan Mazdadi Muhammad Khairin Nahwan Muhammad Nadim Mubaarok Muhammad Reza Faisal, Muhammad Reza Muhammad Ridha Maulidi Muhammad Rusli Muliadi Muliadi Muliadi Muliadi Aziz Muliadi Muliadi Muliadi Muliadi muliadi muliadi Musyaffa, Muhammad Hafizh Mutiara Ayu Banjarsari Nafis Satul Khasanah Ngo, Luu Duc Noryasminda Nugraha, Muhammad Amir Nugrahadi, Dodon Nurcahyati, Ica Nurlatifah Amini P., Chandrasekaran Patrick Ringkuangan Pirjatullah Pirjatullah Pirjatullah Radityo Adi Nugroho Raidra Zeniananto Ramadhan, As`'ary Rifki Izdihar Oktvian Abas Pullah Rifki Rizki, M. Alfi Rozaq, Hasri Akbar Awal Rudy Herteno Rusdiani, Husna Salsabila Anjani Saputro, Setyo Wahyu Saragih, Triando Hamonangan Sa’diah, Halimatus Setyo Wahyu Saputro Shalehah Suci Permata Sari Syahputra, Muhammad Reza Tajali, Ahmad Ulya, Azizatul Umar Ali Ahmad Wijaya Kusuma, Arizha Winda Agustina YILDIZ, Oktay