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All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Interdental Jurnal Kedokteran Gigi (IJKG) Indonesian Journal of Dental Medicine Sinnun Maxillofacial Journal
Reiska Kumala Bakti
Faculty Of Dental Medicine, Universitas Airlangga, Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Acid fast bacilli detected in the oral swab sample of a pulmonary tuberculosis patient Reiska Kumala Bakti; Ni Made Mertaniasih; Diah Savitri Ernawati; Bagus Soebadi; Priyo Hadi
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 2 (2018): June 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v51.i2.p91-94

Abstract

Background: Tuberculosis (TB) is an infectious disease that persists as a health problem worldwide. Mycobacterium tuberculosis, as an etiological agent, is transmitted from infected to uninfected individuals via airborne droplet nuclei. Oral health care workers or dental practitioners may be at high risk of TB infection because of their close proximity to infected individuals during treatment procedures. Simple and rapid screening of mycobacterium tuberculosis in the oral cavity is necessary in order to prevent transmission of infection. Purpose: To investigate the presence of acid-fast bacilli in the buccal mucosa of pulmonary TB patients. Methods: Nineteen pulmonary TB patients of both sexes, ranging in age from 19 to 74 years old participated in this study. The diagnosis of tuberculosis was performed by clinical symptom assessment and supporting examination, including acid-fast bacilli on sputum examination. Two buccal mucosa swabs taken from pulmonary TB patients were collected for acid fast bacilli direct smear by Ziehl Neelsen staining. Results: With regard to mycobacterium tuberculosis, acid-fast bacilli presented in 10.5% of the oral buccal mucosa swabs of subjects, whereas in the sputum specimens, bacilli were found in 52.6% of subjects. Conclusion: Acid-fast bacilli can be found in the buccal epithelial mucosa of pulmonary tuberculosis patients, although its presence was very limited.
Prevalensi Lesi Oral sebagai Manifestasi HIV/AIDS pada Orang Dengan HIV (ODHIV) yang Mengonsumsi Highly Active Antiretroviral Therapy di Komunitas Mahameru Surabaya Indonesia Radithia, Desiana; Ernawati, Diah Savitri; Bakti, Reiska Kumala; Pratiwi, Aulya Setyo; Ayuningtyas, Nurina Febriyanti; Mahdani, Fatma Yasmin; Pasaribu, Togu Andrie Simon; Puspasari, Karlina; Pramitha, Selviana Rizky; Dewi, Gremita Kusuma
Sinnun Maxillofacial Journal Vol. 6 No. 01 (2024): April 2024
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/smj.v6i01.127

Abstract

Pendahuluan: Terjadinya lesi oral pada Orang Dengan HIV (ODHIV) telah banyak dihubungkan dengan peningkatan viral load, penurunan jumlah CD4+, dan konsumsi Highly Active Antiretroviral Therapy (HAART) yang walaupun penggunaannya dapat meningkatkan kondisi umum ODHIV, tetapi penggunaan dalam jangka panjang juga akan memicu berbagai perubahan secara sistemik dan lokal. Tujuan Penelitian: Penelitian ini bertujuan untuk mendata prevalensi terjadinya lesi oral pada ODHIV yang menggunakan HAART. Metode: Penelitian ini menggunakan jenis penelitian observasi cross sectional dengan total sampling sesuai dengan STOBE statement. Data dicatat pada formulir kuesioner dan formulir pemeriksaan klinis. Hasil: Sebanyak total 40 orang peserta dilaporkan dalam penelitian ini. Jenis HAART yang paling banyak dilaporkan penggunaannya dalam jangka panjang tanpa perubahan adalah TLD (27,5%), sementara jenis terapi dengan perubahan regimen adalah terapi awal dengan Duviral Neviral menjadi terapi dengan TLD (12,5%). Durasi terapi HAART selama lebih dari 3 tahun tercatat pada 29 peserta (72,5%) dan durasi terapi kurang dari 3 tahun tercatat pada 11 peserta (27,5%). Lesi oral yang paling banyak diobservasi adalah diffuse oral hyperpigmentation (47,62%), diikuti oleh coated tongue (23,81%), traumatic ulcer (4,76%), linea alba (4,76%), torus palatinus (4,76%), dan lesi-lesi lainnya. Kesimpulan: Lesi oral yang paling banyak ditemukan adalah oral diffuse hyperpigmentation dan korelasinya dengan penggunaan HAART masih perlu ditelaah lebih lanjut.
The Role of Mycobacterium Tuberculosis Detection on Oral Mucosa in Diagnosis of Pulmonary Tuberculosis Bakti, Reiska Kumala; Soebadi, Bagus; Ernawati, Diah Savitri; Mertaniasih, Ni Putu Made
Indonesian Journal of Dental Medicine Vol. 6 No. 1 (2023): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v6i1.2023.8-12

Abstract

Background. Tuberculosis is one of the world's health problems, with larger mortality rate than HIV/AIDS. In order to control this disease, a new and inexpensive diagnostic method is needed. Oral samples, such as buccal mucosa epithelium, can be an alternative specimen, other than sputum, in the diagnosis of tuberculosis. Purpose. This study aimed to analyze the presence of Mycobacterium tuberculosis on buccal swabbing of tuberculosis patients. Method. Study was conducted on 18 new pulmonary tuberculosis patients in TB DOTS unit of Dr. Soetomo General Hospital. Each subject was swabbed on the buccal mucosa of the oral cavity for subsequent examination of PCR, AFB, and culture to detect Mycobacterium tuberculosis in the oral cavity. Result. The results showed that Mycobacterium tuberculosis was detected from 2 study subjects (11%) using PCR, whereas in AFB and culture examination methods no Mycobacterium tuberculosis was detected on buccal mucosa of the oral cavity. Conclusion. This study showed that Mycobacterium tuberculosis was detected on buccal mucosa swab of tuberculosis patients based on PCR technique, but this method is less suitable in diagnosis of pulmonary tuberculosis.
Presence of Klebsiella Pneumoniae on Black Hairy Tongue as Oral Microbiome Dysbiosis Bakti, Reiska Kumala; Pradnyani , I Gusti Agung Sri; Subarnbhesaj, Ajiravudh; Radithia, Desiana
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 2 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i2.12176

Abstract

Introduction: Black hairy tongue (BHT) is a benign condition characterized by discoloration and elongation of filiform papillae. Although asymptomatic, it can trap microorganisms, potentially contributing to oral dysbiosis. The pathogenesis is still unclear, but smoking, drugs, alcohol, or excessive coffee/tea consumption trigger it. Diagnosis relies on history-taking, clinical assessment, and occasionally microscopic evaluation. This case report aims to show an interesting finding in the microbiological examination of black hairy tongue. Case: A 33-year-old male smoker and coffee drinker presented with black tongue discoloration. Any medication use and a history of systemic diseases are denied, but he had a habit of smoking, staying up late, and heavy coffee consumption. Case Management: Clinical assessment and microbiological swab analysis for bacterial and fungal identification were conducted. Microbiological examination revealed the presence of Klebsiella pneumoniae, a colonizing opportunistic pathogen. Discussion: The patient reported no systemic diseases or medication use, with lifestyle factors identified as potential triggers. This case underscores the role of lifestyle factors and oral hygiene in the development of BHT and its association with microbial dysbiosis. Conclusion: The detection of K. pneumoniae emphasizes the need for microbial evaluation in persistent cases to prevent potential systemic effects.
Korelasi antara profil darah lengkap dengan waktu penyembuhan Recurrent Aphthous Stomatitis: observasional analitik Rajah, Karthiyayinee Alagir; Ayuningtyas, Nurina Febriyanti; Parmadiati, Adiastuti Endah; Radithia, Desiana; Mahdani, Fatma Yasmin; Pratiwi, Aulya Setyo; Bakti, Reiska Kumala; Dewi, Gremita Kusuma
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 2 (2025): Agustus 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i2.61016

Abstract

Pendahuluan: Recurrent Aphthous Stomatitis (RAS) merupakan salah satu penyakit pada mukosa rongga mulut yang paling sering dijumpai. RAS timbul dengan berbagai faktor predisposisi, disertai rasa nyeri, dengan waktu penyembuhan yang berbeda-beda. Tes darah lengkap adalah tes darah mengukur beberapa komponen darah termasuk sel darah merah, sel darah putih, hemoglobin, hematokrit dan trombosit. Di antara faktor etiologi RAS diketahui faktor inflamasi yang berperan. Secara teori, diketahui bahwa neutrofil dan limfosit bertanggung jawab terhadap terjadinya inflamasi. Penelitian ini bertujuan untuk menganalisis apakah terdapat korelasi antara profil hitung darah lengkap dan waktu penyembuhan RAS. Metode: Penelitian ini adalah penelitian analitik observasional dengan rancangan potong-lintang (cross-sectional). Metode pengambilan sampel dalam penelitian ini adalah total sampling. Penelitian ini menggunakan 20 pasien yang sedang mengalami RAS. Data pasien didapatkan dari rekam medik RSGM Universitas Airlangga. Data yang diambil lengkap dengan tes darah pasien serta waktu penyembuhan RAS. Data dari kedua variabel dianalisis menggunakan uji korelasi statistik. Korelasi Pearson digunakan ketika data terdistribusi secara normal sedangkan Spearman's Rho digunakan ketika data tidak terdistribusi secara normal. Hasil: Hasil uji korelasi Pearson antara limfosit dan waktu penyembuhan RAS dengan nilai r=-0,459 ; p=0,042 menunjukkan nilai korelasi negatif yang berarti semakin tinggi kadar limfosit maka semakin rendah waktu penyembuhan RAS. Limfosit, trombosit, eosinofil dan LED juga menunjukkan nilai korelasi negatif tetapi tidak signifikan karena p>0,05. Tidak ada nilai signifikan yang ditemukan pada variabel lain kecuali limfosit dan MCHC. Simpulan: terdapat korelasi antara profil darah lengkap (limfosit dan MCHC) dengan waktu penyembuhan RAS.The correlation between complete blood profile and healing time of Recurrent Aphthous Stomatitis: analytical observationalIntroduction: Recurrent Aphthous Stomatitis (RAS) is one of the most common oral mucosa diseases. RAS occurs with various predisposing factors, accompanied by pain, and has varying healing times. A complete blood count is a blood test that measures several blood components, including red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. Among the etiological factors of RAS, inflammatory factors are known to play a role. In theory, it is known that neutrophils and lymphocytes are responsible for inflammation. Methods: This study is an observational analytical study with a cross-sectional design. The sampling method in this study is total sampling. This study used 20 patients who were experiencing RAS. Patient data has been obtained from the medical records of RSGM Universitas Airlangga. The data is complete, including patient blood tests and RAS healing time. Data from both variables were analyzed using statistical correlation tests. Pearson correlation is used when the data is normally distributed, while Spearman's Rho is used when the data is not normally distributed. Results: The results of the Pearson correlation test between lymphocytes and RAS healing time with a value of r = -0,459; p = 0,042 showed a negative correlation value, meaning that the higher the lymphocyte levels, the lower the RAS healing time. Lymphocytes, platelets, eosinophils, and LED also showed negative correlation values but were not significant because p>0,05. No significant values were found in other variables except lymphocytes and MCHC. Conclusion: a correlation exists between complete blood profile (lymphocytes and MCHC) and RAS healing time.
Co-Authors Adiastuti Endah Parmadiati Bagus Soebadi Bagus Soebadi, Bagus Desiana Radithia, Desiana Dewi, Gremita Kusuma Diah Savitri Ernawati Fatma Yasmin Mahdani Mertaniasih, Ni Putu Made Ni Made Mertaniasih Nurina Febriyanti Ayuningtyas Pasaribu, Togu Andrie Simon Pradnyani , I Gusti Agung Sri Pramitha, Selviana Rizky Pratiwi, Aulya Setyo Priyo Hadi Puspasari, Karlina Rajah, Karthiyayinee Alagir Subarnbhesaj, Ajiravudh