Article Per Year (5 Year)
p-Index From 2020 - 2025
1.503
P-Index
This Author published in this journals
All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Indonesian Journal of Dental Medicine Sinnun Maxillofacial Journal
Fatma Yasmin Mahdani
Department Of Oral Medicine, Faculty Of Dental Medicine, Universitas Airlangga
Dentistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 9 Documents
Search

 1 
The decrease of fibroblasts and fibroblast growth factor-2 expressions as a result of X-ray irradiation on the tooth extraction socket in Rattus novergicus Fatma Yasmin Mahdani; Intan Nirwana; Jenny Sunariani
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 2 (2015): June 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1236.195 KB) | DOI: 10.20473/j.djmkg.v48.i2.p94-99

Abstract

Background: Wound healing involves cellular, molecular, physiological, and biochemical processes as responses to tissue damage. For instance, when a failure during tooth extraction occurs, radiographic examination, X-rays, is required. X-rays as an enforcer diagnosis can damage DNA chain, resulting in cell death and inhibition of wound healing process. Purpose: This research aims to analyze fibroblasts cell number and fibroblast growth factor-2 (FGF-2) expressions during wound healing process after tooth extraction as a result of X-ray irradiation. Methods: There were three research groups, each consisting of ten rats. Incisor tooth extraction was performed on the left lower jaw, and then X-ray examination was conducted at certain irradiation doses, namely 0 mSv, 0.08 mSv, and 0.16 mSv. Those animals were sacrificed on day 3, and on day 7 after the extraction, histopathology and immunohistochemistry examinations were conducted to determine fibroblast cell number and FGF-2 expressions. Data obtained were then analyzed by oneway ANOVA and Tukey HSD tests. Results: The number of fibroblasts decreased significantly in the group with the irradiation dose of 0.16 mSv applied on day 7 after the extraction (p <0.05). Similarly, the number of FGF-2 expressions decreased significantly in the group with the irradiation dose of 0.16 mSv applied on days 3 and 7 after the extraction (p <0.05). Conclusion: X-ray irradiation at a dose of 0.16 mSv can inhibit the healing process of tooth extraction wound due to the decreasing of fibroblasts cell number and FGF-2 expressions.
Clinical appearance of acute pseudomembranous candidiasis in children and the importance of good communication, information and education to patients: A case report Afryla Femilian; Winda Dwi Malinda Masuku; Nurina Febriyanti Ayuningtyas; Diah Savitri Ernawati; Fatma Yasmin Mahdani; Meircurius Dwi Condro Surboyo
Dental Journal (Majalah Kedokteran Gigi) Vol. 55 No. 2 (2022): June 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i2.p105-108

Abstract

Background: Oral candidiasis is a common opportunistic infection of the oral cavity caused by an overgrowth of the Candida species, in particular, Candida albicans. The incidence varies depending on age and certain predisposing factors. In the practice of dentistry, doctor-patient communication is an important component. Effective communication between doctor and patient is needed to convey information and educate patients so that treatment can be administered appropriately. Purpose: This case aimed to discuss the clinical appearance of acute pseudomembranous candidiasis (APC) in children and the importance of good communication, information and education of patients. Case: A five-year-old male patient came with his mother on November 6, 2020 complaining of white deposits on the mucosa of the upper and lower lips that had been present for a week. Case management: The diagnosis was defined as a typical APC lesion although the potassium hydroxide (KOH) test showed negative results. Characteristic lesions found in APC are often seen clearly in some cases and treatment can begin immediately. Patients receive the empirical therapy, Nystatin oral suspension 100.000 i.u, and the patient is instructed to maintain optimal oral hygiene care, maintain nutrient intake and book a follow-up consultation. Conclusion: Mistakes in patient preparation procedures in taking supporting examinations will result in false negative/positive results, so communication and education information regarding the preparation of supporting examinations for patients is important to note.
Knowledge of orofacial pain in students of the Dental Professional Program Faculty of Dental Medicine, Universitas Airlangga Desvia Nuzela Qurzani Hariyadi; Ari Hapsari Tri Wardani; Saka Winias; Fatma Yasmin Mahdani; Adiastuti Endah Parmadiati; Nurina Febriyanti Ayuningtyas; Meircurius Dwi Condro Surboyo
Dental Journal Vol. 56 No. 1 (2023): March 2023
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i1.p36-40

Abstract

Background: Orofacial pain is associated with the hard and soft tissues of the head, face, and neck. Knowledge of orofacial pain helps in getting information on clinical symptoms, trigger factors, and risks of orofacial pain, as well as clinical and supportive examinations for identifying the pain. The dental professional students’ knowledge influences the ability to diagnose and decide on an appropriate treatment plan. This knowledge is seen from the intelligence level in obtaining information about orofacial pain. Purpose: To describe the level of knowledge of orofacial pain in the students of the Dental Professional Program, Faculty of Dental Medicine, Universitas Airlangga, based on intelligence level. Methods: This research was a descriptive study. Data was taken using a questionnaire on google form with a simple random sampling data technique and was analyzed using SPSS version 25. Results: The majority understand the general description of postherpetic neuralgia (PHN), as well as the risk factors and triggers (93.4% and 87.8%, respectively) associated with it. Further, 90.6% understand burning mouth syndrome (BMS) and the clinical symptoms of PHN. BMS based on clinical examination and support is understood by 96.1%, and 82.9% know how to manage trigeminal neuralgia (TN). Intelligence level is divided into three categories, namely source of knowledge (55.8% are from lectures, journals, and textbooks), material repetition (77.3% never repeated), and retention of material (65.2% no retention). Conclusion: Students’ knowledge of orofacial pain is good, but the relationship between the level of intelligence and knowledge is not yet known.
Prevalensi Lesi Oral sebagai Manifestasi HIV/AIDS pada Orang Dengan HIV (ODHIV) yang Mengonsumsi Highly Active Antiretroviral Therapy di Komunitas Mahameru Surabaya Indonesia Radithia, Desiana; Ernawati, Diah Savitri; Bakti, Reiska Kumala; Pratiwi, Aulya Setyo; Ayuningtyas, Nurina Febriyanti; Mahdani, Fatma Yasmin; Pasaribu, Togu Andrie Simon; Puspasari, Karlina; Pramitha, Selviana Rizky; Dewi, Gremita Kusuma
Sinnun Maxillofacial Journal Vol. 6 No. 01 (2024): April 2024
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/smj.v6i01.127

Abstract

Pendahuluan: Terjadinya lesi oral pada Orang Dengan HIV (ODHIV) telah banyak dihubungkan dengan peningkatan viral load, penurunan jumlah CD4+, dan konsumsi Highly Active Antiretroviral Therapy (HAART) yang walaupun penggunaannya dapat meningkatkan kondisi umum ODHIV, tetapi penggunaan dalam jangka panjang juga akan memicu berbagai perubahan secara sistemik dan lokal. Tujuan Penelitian: Penelitian ini bertujuan untuk mendata prevalensi terjadinya lesi oral pada ODHIV yang menggunakan HAART. Metode: Penelitian ini menggunakan jenis penelitian observasi cross sectional dengan total sampling sesuai dengan STOBE statement. Data dicatat pada formulir kuesioner dan formulir pemeriksaan klinis. Hasil: Sebanyak total 40 orang peserta dilaporkan dalam penelitian ini. Jenis HAART yang paling banyak dilaporkan penggunaannya dalam jangka panjang tanpa perubahan adalah TLD (27,5%), sementara jenis terapi dengan perubahan regimen adalah terapi awal dengan Duviral Neviral menjadi terapi dengan TLD (12,5%). Durasi terapi HAART selama lebih dari 3 tahun tercatat pada 29 peserta (72,5%) dan durasi terapi kurang dari 3 tahun tercatat pada 11 peserta (27,5%). Lesi oral yang paling banyak diobservasi adalah diffuse oral hyperpigmentation (47,62%), diikuti oleh coated tongue (23,81%), traumatic ulcer (4,76%), linea alba (4,76%), torus palatinus (4,76%), dan lesi-lesi lainnya. Kesimpulan: Lesi oral yang paling banyak ditemukan adalah oral diffuse hyperpigmentation dan korelasinya dengan penggunaan HAART masih perlu ditelaah lebih lanjut.
Current Approaches of Salivary Glands Regeneration for Management of Xerostomia and Hyposalivation: A Narrative Review Mahdani, Fatma Yasmin; Ayuningtyas, Nurina Febriyanti
Indonesian Journal of Dental Medicine Vol. 6 No. 1 (2023): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v6i1.2023.43-46

Abstract

Background: The salivary glands are the organs that produce saliva and have a role keeping the oral cavity moist and lubricated. Salivary glands regeneration is important for developing treatments on management of xerostomia and hyposalivation because of the irreversible damage of salivary glands. Common causes include aging, polypharmacy, autoimmune disease, including Sjogren's syndrome, and head and neck radiation, in which xerostomia and hyposalivation having a substantial impact on patient health and wellbeing. Purpose: to describe current approach of salivary glands regeneration for management of xerostomia and hyposalivation through narrative review. Review(s): A literature search using Science Direct and PubMed yielded results between 1973 and 2022, and the results were evaluated to identify the most promising approaches and for future research. The keywords of the search strategy were "salivary gland regeneration” and "xerostomia” or "hyposalivation”. Current studies have revealed potential targets in the development of salivary gland regeneration for the management of xerostomia and hyposalivation. Stem cells therapy aims to repair damaged at the cellular level, especially stimulating acini cells, multiplying and differentiating to replace dead or damaged acini cells. Bioengineering is through isolated acini cells cultured on many modified cell line and administration of bioactive compounds. Gene therapy aims to rebuild functional water channels and neutralization of inflammatory mediators. Conclusion: Several approaches of salivary glands regeneration that can be taken are stem cells therapy, bioengineering, and gene transfer.
Hubungan Tingkat Pengetahuan Terhadap Sikap Orang dengan HIV/AIDS pada Oral Hairy Leukoplakia dan Kandidiasis Oral Radithia, Desiana; Ernawati, Diah Savitri; Surboyo, Meircurius Dwi Condro; Ayuningtyas, Nurina Febriyanti; Mahdani, Fatma Yasmin; Pratiwi, Aulya Setyo; Sismiyanti, Rossy; Kuntardjo, Yuhanna; Puspitasari, Yeni
Sinnun Maxillofacial Journal Vol. 6 No. 02 (2024): Oktober 2024
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/smj.v6i02.128

Abstract

Pendahuluan: HIV/AIDS telah menjadi masalah kesehatan masyarakat global. Infeksi HIV dapat menyebabkan gangguan kekebalan tubuh dan bermanifestasi di beberapa tempat baik secara sistemik maupun di rongga mulut. Manifestasi oral yang paling umum terkait dengan HIV/AIDS adalah Kandidiasis Oral dan Oral Hairy Leukoplakia. Sebagai orang yang hidup dengan HIV/AIDS (ODHIV) mungkin menemukan manifestasi tersebut, pengetahuan mereka dapat menentukan sikap mereka terhadap temuan tersebut.Tujuan Penelitian: Mengamati sikap ODHIV di kota Surabaya terhadap dua manifestasi oral HIV yang paling umum ditemukan, yaitu Oral Hairy Leukoplakia dan Kandidiasis Oral, serta menentukan hubungan antara pengetahuan dan sikap mereka terhadap hal tersebut. Bahan dan Metode: Sebanyak 30 responden diberikan kuesioner untuk menilai pengetahuan dan sikap mereka mengenai Oral Hairy Leukoplakia dan Kandidiasis Oral. Pengetahuan didefinisikan dengan kriteria baik, cukup, dan rendah. Sikap didefinisikan sebagai positif, netral, dan negatif. Hasil: Tingkat pengetahuan mengenai Oral Hairy Leukoplakia dan Kandidiasis  Oral menunjukkan hasil tinggi (33%), sedang (54%) dan rendah (13%). Responden menunjukkan sikap positif (30%) dan sikap tidak setuju (27%), sedangkan netral (43%). Terdapat hubungan positif yang signifikan antara tingkat pengetahuan responden dengan sikap mereka (p = 0,46). Kesimpulan: Terdapat hubungan antara pengetahuan yang baik dengan sikap positif pada masyarakat.
Knowledge of xerostomia in the elderly in Rejosari Village, Lamongan Regency, East Java Sukmawati, Natasya Fauzia; Ratna Fitri, Adinda; Radithia, Desiana; Parmadiati, Adiastuti Endah; Ayuningtyas, Nurina Febriyanti; Mahdani, Fatma Yasmin
Indonesian Journal of Dental Medicine Vol. 8 No. 1 (2025): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v8i1.2025.19-24

Abstract

Background: Xerostomia, or dry mouth, is a subjective sensation often linked to hyposalivation, affecting oral and overall health. With a global prevalence of 5.5% to 46%, it is more common in the elderly due to factors like polypharmacy, systemic diseases, and age-related salivary gland changes. Xerostomia impacts daily activities such as speaking, chewing, and swallowing, reducing quality of life. Rejosari Village in Lamongan Regency, East Java, has a high elderly population and a well-established healthcare center for seniors (Posyandu Lansia), making it an ideal setting for studying awareness and knowledge of xerostomia. Purpose: To describe the level of knowledge of xerostomia among elderly people in Rejosari Village, Lamongan Regency, East Java. Methods: This descriptive observational study utilized an online questionnaire distributed via Google Forms. Participants were selected through consecutive sampling, focusing on elderly individuals who met the inclusion criteria. Of the 75 respondents who completed the questionnaire, 70 were included in the final analysis. Data were analyzed descriptively, categorizing knowledge levels into high, moderate, and low. Results: Among the 70 eligible respondents, 70.00% exhibited a high level of knowledge about xerostomia. Meanwhile, 22.86% were classified as having moderate knowledge, and 7.14% had low knowledge levels. These findings indicate that most elderly residents in Rejosari Village are well-informed about xerostomia, although knowledge gaps persist among certain groups. Conclusion: The elderly’s knowledge about xerostomia in Rejosari Village, Lamongan Regency, East Java is dominated in the high knowledge category.
White sponge nevus as a hereditary disease: A brief narrative review Mahdani, Fatma Yasmin; Puspasari, Karlina; Manuaba, Ida Bagus Pramana Putra; Putri, Salsabila Fitriana; Ayunnisa, Naqiya; Ernawati, Diah Savitri; Hendarti, Hening Tuti
Indonesian Journal of Dental Medicine Vol. 8 No. 1 (2025): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v8i1.2025.49-52

Abstract

Background: White sponge nevus (WSN) is an autosomal dominant hereditary genetic disorder characterized by thickened keratin in the oral mucosa that appears folded, wavy, spongy, thick, and rough. WSN do not have the potential to become malignant, but an accurate diagnosis is still needed to prevent unnecessary treatment and reduce potential remissions and exacerbations due to infection. Purpose: to provide a detailed description of white sponge nevus as a hereditary disease by means of narrative review. Review: A literature search using ScienceDirect and PubMed yielded results between 2012 and 2024. The keywords of the search strategy were “hereditary disease” and “white sponge nevus” or “Cannon’s disease” or “white folded gingivostomatitis” or “leukokeratosis.”. White sponge nevus (WSN) was first discovered by Hyde in 1909 and usually occurs in children and people under 20 years old. The main etiology of WSN is an autosomal dominant hereditary genetic disorder; KRT4 and KRT13 are specific keratin encoders that cause WSN, and there are predisposing factors such as bacterial infection, smoking, and alcohol consumption. Conclusion: In determining the diagnosis of WSN, it is necessary to carry out blood tests, subjective examinations, objective examinations, and supporting examinations in the form of exfoliative cytology and biopsies. As well as the need for comprehensive treatment, even though the prognosis of this disorder is good.
Korelasi antara profil darah lengkap dengan waktu penyembuhan Recurrent Aphthous Stomatitis: observasional analitik Rajah, Karthiyayinee Alagir; Ayuningtyas, Nurina Febriyanti; Parmadiati, Adiastuti Endah; Radithia, Desiana; Mahdani, Fatma Yasmin; Pratiwi, Aulya Setyo; Bakti, Reiska Kumala; Dewi, Gremita Kusuma
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 2 (2025): Agustus 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i2.61016

Abstract

Pendahuluan: Recurrent Aphthous Stomatitis (RAS) merupakan salah satu penyakit pada mukosa rongga mulut yang paling sering dijumpai. RAS timbul dengan berbagai faktor predisposisi, disertai rasa nyeri, dengan waktu penyembuhan yang berbeda-beda. Tes darah lengkap adalah tes darah mengukur beberapa komponen darah termasuk sel darah merah, sel darah putih, hemoglobin, hematokrit dan trombosit. Di antara faktor etiologi RAS diketahui faktor inflamasi yang berperan. Secara teori, diketahui bahwa neutrofil dan limfosit bertanggung jawab terhadap terjadinya inflamasi. Penelitian ini bertujuan untuk menganalisis apakah terdapat korelasi antara profil hitung darah lengkap dan waktu penyembuhan RAS. Metode: Penelitian ini adalah penelitian analitik observasional dengan rancangan potong-lintang (cross-sectional). Metode pengambilan sampel dalam penelitian ini adalah total sampling. Penelitian ini menggunakan 20 pasien yang sedang mengalami RAS. Data pasien didapatkan dari rekam medik RSGM Universitas Airlangga. Data yang diambil lengkap dengan tes darah pasien serta waktu penyembuhan RAS. Data dari kedua variabel dianalisis menggunakan uji korelasi statistik. Korelasi Pearson digunakan ketika data terdistribusi secara normal sedangkan Spearman's Rho digunakan ketika data tidak terdistribusi secara normal. Hasil: Hasil uji korelasi Pearson antara limfosit dan waktu penyembuhan RAS dengan nilai r=-0,459 ; p=0,042 menunjukkan nilai korelasi negatif yang berarti semakin tinggi kadar limfosit maka semakin rendah waktu penyembuhan RAS. Limfosit, trombosit, eosinofil dan LED juga menunjukkan nilai korelasi negatif tetapi tidak signifikan karena p>0,05. Tidak ada nilai signifikan yang ditemukan pada variabel lain kecuali limfosit dan MCHC. Simpulan: terdapat korelasi antara profil darah lengkap (limfosit dan MCHC) dengan waktu penyembuhan RAS.The correlation between complete blood profile and healing time of Recurrent Aphthous Stomatitis: analytical observationalIntroduction: Recurrent Aphthous Stomatitis (RAS) is one of the most common oral mucosa diseases. RAS occurs with various predisposing factors, accompanied by pain, and has varying healing times. A complete blood count is a blood test that measures several blood components, including red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. Among the etiological factors of RAS, inflammatory factors are known to play a role. In theory, it is known that neutrophils and lymphocytes are responsible for inflammation. Methods: This study is an observational analytical study with a cross-sectional design. The sampling method in this study is total sampling. This study used 20 patients who were experiencing RAS. Patient data has been obtained from the medical records of RSGM Universitas Airlangga. The data is complete, including patient blood tests and RAS healing time. Data from both variables were analyzed using statistical correlation tests. Pearson correlation is used when the data is normally distributed, while Spearman's Rho is used when the data is not normally distributed. Results: The results of the Pearson correlation test between lymphocytes and RAS healing time with a value of r = -0,459; p = 0,042 showed a negative correlation value, meaning that the higher the lymphocyte levels, the lower the RAS healing time. Lymphocytes, platelets, eosinophils, and LED also showed negative correlation values but were not significant because p>0,05. No significant values were found in other variables except lymphocytes and MCHC. Conclusion: a correlation exists between complete blood profile (lymphocytes and MCHC) and RAS healing time.
Co-Authors Adiastuti Endah Parmadiati Ari Hapsari Tri Wardani Ayunnisa, Naqiya Desiana Radithia, Desiana Desvia Nuzela Qurzani Hariyadi Dewi, Gremita Kusuma Diah Savitri Ernawati Femilian, Afryla Hening Tuti Hendarti Intan Nirwana, Intan Jenny Sunariani Kuntardjo, Yuhanna Manuaba, Ida Bagus Pramana Putra Nurina Febriyanti Ayuningtyas Pasaribu, Togu Andrie Simon Pramitha, Selviana Rizky Pratiwi, Aulya Setyo Puspasari, Karlina Puspitasari, Yeni Putri, Salsabila Fitriana Rajah, Karthiyayinee Alagir Ratna Fitri, Adinda Reiska Kumala Bakti Saka Winias Sismiyanti, Rossy Sukmawati, Natasya Fauzia Surboyo, Meircurius Dwi Condro Winda Dwi Malinda Masuku