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All Journal Medicina Sari Pediatri Paediatrica Indonesiana ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Riset Kesehatan Nasional
Ni Putu Siadi Purniti
Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Udayana
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Forced expiratory volume in 1-second and blood gas analysis in children during asthma attacks Dewa Ayu Dini Primashanti; Putu Siadi Purniti; I Gusti Ayu Trisna Windiani
Paediatrica Indonesiana Vol 58 No 5 (2018): September 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.136 KB) | DOI: 10.14238/pi58.5.2018.221-6

Abstract

Background Asthma is the most common chronic disease in the world, with a high incidence in children. Blood gas analysis and pulmonary function test using spirometry are recommended to evaluate the degree of asthma in children. Spirometry test is non-invasive and easier to implement compared to blood gas analysis. Objective To evaluate for a possible correlation between forced expiratory volume in 1 second (FEV1) measured by spirometry test and blood gas analysis (pO2 and pCO2 levels) in children during an asthma attack. Methods This cross-sectional study was done in children with asthma attacks who were admitted to Sanglah Hospital, Denpasar, Bali, between November 2016 and April 2017. Subjects underwent spirometry tests and blood gas analyses. Potential correlations between FEV1 and pO2 and pCO2 levels were analyzed by Spearman’s correlation test. Results A total of 50 subjects, consisting of children aged 6 to 12 years, were diagnosed with asthma attacks during the study period. Subjects’ mean FEV1 level was 43.6%, mean pCO2 was 38.36 mmHg, and mean pO2 was 121.92 mmHg. There were no significant correlations between FEV1 and pCO2 level (r=0.206; P=0.152) or FEV1 and pO2 (r=0.157; P=0.277) found in this study. Conclusion FEV1 does not correlate with pCO2 and pO2 level in children during asthma attacks.
Growth of HIV-exposed infants from birth to 6 months in the prevention of mother-to-child transmission program Maria Priskila; Ketut Dewi Kumarawati; Ni Putu Siadi Purniti
Paediatrica Indonesiana Vol 59 No 4 (2019): July 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.723 KB) | DOI: 10.14238/pi59.4.2019.183-7

Abstract

Background Human immunodeficiency virus (HIV) infection is a global health issue. Most cases of HIV infection in children are acquired through transmission from HIV-infected mothers. Maternal HIV infection affects infant growth. Objective To evaluate the first six months of growth in HIV-exposed infants born to mothers in the prevention of mother-to-child transmission (PMTCT) program. Methods This prospective cohort study was done in 40 HIV-exposed infants born in Sanglah General Hospital, Bali. Subjects' underwent weight and length measurements at birth and monthly for 6 months. Data analyses used were repeated ANOVA test with Bonferonni post-hoc analysis for normally distributed data and Friedman test with Wilcoxon post-hoc analysis for abnormally distributed data. Correlations between birth weight and length to weight and length at 6 months of age were analyzed with Spearman's test. Results Subjects' mean birth weight was 2,900 (SD 546) grams and median birth length was 48 (range 36-52) cm. Subjects' body weight and length increased monthly throughout the measurement period (P<0.001). There was a strong negative correlation between birth weight and infant weight gain at 6 months of age (r=-0.678), and a moderate negative correlation between birth length and infant length gain at 6 months of age (r=-0.564). Conclusion HIV-exposed infants born to mothers in the PMTCT program have a significant body weight and body length growth in the first 6 months of life, and followed general WHO weight and length curves for age.
Hubungan status gizi terhadap angka kejadian community-acquired pneumonia (CAP) pada balita di RSUP Sanglah Denpasar Putu Nandika Wintari; Putu Siadi Purniti
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.646 KB) | DOI: 10.15562/ism.v9i3.178

Abstract

Latar Belakang: Pneumonia hingga saat ini masih tercatat sebagai penyebab utama kematian pada anak-anak. Di rumah sakit, penyakit pneumonia termasuk dalam daftar 10 penyakit penyebab kematian pada penderita rawat inap yakni sebesar 2,92% dari seluruh kematian Pneumonia memiliki beberapa faktor resiko yang dapat memperberat penyakit tersebut antara lain adalah status gizi yang dimiliki penderita. Penelitian ini bertujuan untuk melihat hubungan antara status gizi dengan angka kejadian pneumonia.Metode: Disain penelitian adalah cross-sectional study dengan sampel 168 orang. Sebagai variabel bebas adalah status gizi sedangkan pneumonia sebagai variabel tergantung. Data yang digunakan diambil dari buku catatan pasien SMF Ilmu Kesehatan Anak RSUP Sanglah.Hasil: Dari sampel yang berjumlah 168 orang, ternyata 119 orang dengan gizi baik, dan 49 orang dengan gizi buruk. Pasien yang mengalami pneumonia adalah 84 orang dan yang bukan mengalami pneumonia adalah 84 orang. Hasil uji bivariat menunjukkan adanya hubungan yang bermakna antara status gizi dengan angka kejadian pneumonia p = 0,011 (p < 0,05), dengan nilai OR sebesar 2,425 (95% CI 0,216 - 4,839).Simpulan: Dari hasil penelitian ini dapat disimpulkan bahwa ada hubungan yang bermakna antara status gizi dan angka kejadian pneumonia pada pasien anak yang dirawat di SMF Ilmu Kesehatan Anak RSUP Sanglah.
HUBUNGAN JENIS KELAMIN, STATUS GIZI DAN BERAT BADAN LAHIR DENGAN ANGKA KEJADIAN ISPA PADA BALITA DI PUSKESMAS BANJARANGKAN II TAHUN 2016 Putu Meitri Nirmala Utami; Putu Siadi Purniti; I Made Arimbawa
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.054 KB) | DOI: 10.15562/ism.v9i3.216

Abstract

ABSTRAKInfeksi saluran pernapasan akut (ISPA) adalah penyakit infeksi akut yang menyerang salah satu bagian dan atau lebih dari saluran napas. ISPA sering dijumpai di negara-negara berkembang. Sebagai negara berkembang, Indonesia menduduki posisi keempat bersama dengan Bangladesh dan Nigeria. Sedangkan Bali memiliki angka periode prevalensi sebesar 22,6% dimana angka tersebut tidak jauh dari angka periode prevalensi ISPA di Indonesia yaitu 25,0%. Tujuan penelitian ini untuk melihat faktor-faktor yang berhubungan dengan ISPA terutama jenis kelamin, status gizi dan berat badan lahir terhadap balita penderita ISPA. Penelitian ini menggunakan studi analitik cross-sectional. Sampel yang digunakan berjumlah 223 orang yang diambil secara konsekutif di Puskesmas Banjarangkan II Klungkung pada rentang waktu 1 Januari 2016 s.d. 31 Desember 2016. Data penelitian adalah data sekunder dari rekam medis pasien. Hasil penelitian menunjukan bahwa balita dengan ISPA cenderung lebih banyak pada usia 1-3 tahun (57,9%), jenis kelamin laki-laki (62,6%), status gizi baik (89,9%), dan berat badan lahir normal (88,5%). Hasil analisis menggunakan uji chi-square menyatakan terdapat hubungan yang bermakna antara jenis kelamin (p=0,003), status gizi (p<0,0001), dan berat badan lahir (p<0,0001) dengan angka kejadian ISPA pada balita.Terdapat hubungan bermakna antara variabel jenis kelamin, status gizi dan berat badan lahir dengan angka kejadian ISPA pada balita.Kata Kunci: balita, ISPA, jenis kelamin, status gizi, berat badan lahir ABSTRACTTHE RELATION BETWEEN GENDER, NUTRITIONAL STATUS, AND BIRTH WEIGHT WITH THE INCIDENCE OF URTI IN CHILDREN BELOW 5 YEARS OLD AT PUSKESMAS BANJARANGKAN II IN 2016Upper respiratory tract infection (URTI) is an acute infection disease affecting one or more upper respiratory tracts. This infection is often found in developing countries. As a developing country, Indonesia holds the fourth position together with Bangladesh and Nigeria. Meanwhile, Bali has the prevalence number of 22.6% in which this number is not much different with Indonesia’s of 25.0%. The objective of this study was to find out the factors which were related to upper respiratory tract infection such as gender, nutritional status, and birth weight of children below 5 years old infected with URTI in particular. This research was a cross sectional analytic study involving 223 samples who were gathered consecutively at Puskesmas Banjarangkan II Klungkung from 1 january 2016 till 31 December 2016. The data obtained were secondary data in form of medical records. The result showed that children with URTI tended to be 1-3 years old (57.9%), male (62.6%), and have good nutritional status (89.9%) and normal birth weight (88.5%). The data were analyzed using Chi-square test which showed that there was significant relation between gender (p=0.003), nutritional status (p<0.0001), and birth weight (p<0.0001) with the URTI incidence in children below 5 years old.There was significant relation between gender, nutritional status, and birth weight with the URTI incidence in children below 5 years old.Keywords: children below 5 years old, upper respiratory tract infection, gender, nutritional status, birth weight
Implementasi lintas diare dan penggunaan obat antidiare pada anak dengan diare Vidya Lakshmi Anbhuselvam; I Putu Gede Karyana; Ni Putu Siadi Purniti
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.236 KB) | DOI: 10.15562/ism.v10i3.488

Abstract

Introduction: Diarrhea is still a major problem that causes illness and death for children in Indonesia. Inappropriate care, both at home and in health agencies, is a major cause of deaths of children with diarrhea.Method: The design of this study was descriptive with a cross sectional study design. The design of this study aims to be able to describe the implementation of cross diarrhea and the use of antidiarrheal drugs for pediatric patients with diarrhea at RSUP Sanglah Denpasar. The data used in the form of secondary data obtained from the medical records of Sanglah Hospital RSUP patients Denpasar January 2017-April 2017. The technique of determining the sample used is total sampling where all target populations that meet the criteria are included as samples.Result: The most widely used cross group of diarrheas was ORS (Oral Rehydration solution) (17.9%). The most commonly used antidiarrhea drug is adsorbent (11.6%).Conclusion: The most widely used cross-diarrhea group was ORS (Oral Rehydration solution) followed by the antibiotic group and so on the zinc group. There are minority cases that have given negative results on antibiotics. The most widely used group of antidiarrheal drugs was the adsorbent followed by the class of antimotility drugs and so on other classes of drugs such as probiotics and herbal medicinesLatar Belakang: Diare masih menjadi masalah utama yang menyebabkan sakit dan kematian bagi anak-anak di Indonesia. Perawatan yang tidak tepat, baik dirumah maupun di instansi kesehatan, merupakan penyebab utama kematian anak-anak dengan diare.Metode: Rancangan penelitian ini bersifat deskriptif dengan rancangan penelitian cross sectional. Rancangan penelitian ini bertujuan untuk dapat menggambarkan implementasi lintas diare dan penggunaan obat antidiare terhadap pasien anak dengan diare di RSUP Sanglah Denpasar. Data yang digunakan berupa data sekunder yang didapat dari rekam medis pasien Anak RSUP Sanglah Denpasar bulan Januari 2017-April 2017. Teknik penentuan sampel yang digunakan adalah total sampling dimana seluruh populasi target yang memenuhi kriteria dimasukan sebagai sampel.Hasil: Golongan lintas diare paling banyak digunakan adalah cairan rehidrasi yaitu oralit sebanyak 34 (17,9%). Penggunaan obat antidiare paling sering digunakan adalah adsorben sebanyak 22 (11,6%).Simpulan: Golongan lintas diare paling banyak digunakan adalah cairan rehidrasi yaitu oralit diikuti oleh golongan antibiotik dan seterusnya golongan zink. Terdapat kasus minoritas yang telah memberi hasil negatif pada pemberian antibiotik. Golongan penggunaan obat antidiare paling banyak digunakan adalah adsorben diikuti oleh golongan obat antimotilitas dan seterusnya golongan obat lain-lain seperti probiotik dan obat herbal
Korelasi kadar laktat dengan Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE II) pada neonatus yang dirawat di NICU RSUP Sanglah, Bali, Indonesia I Gede Deden Susma Sugara; I Wayan Dharma Artana; Ketut Suarta; Soetjiningsih Soetjiningsih; Ni Putu Siadi Purniti; Dyah Kanya Wati; Made Sukmawati; Made Kardana
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (423.462 KB) | DOI: 10.15562/ism.v10i2.505

Abstract

Background: Infant mortality rate is one of the indicators of public health degree that determines the human development index. Various attempts were made to early detect the problems, one of which was by assessing the severity of neonatal disease using Score for Neonatal Acute Physiology Perinatal Extension-II (SNAPPE II) which was associated with lactate levels as a metabolic response and organ dysfunction due to critical illness that were suffered at the Neonatal Intensive Care Unit (NICU).Methods: A cross-sectional analytic study was conducted among 48 critically ill neonates treated at the Sanglah Hospital Denpasar NICU. Samples were selected from affordable populations by consecutive sampling. Data analysis was performed by Saphiro-Wilk data normality test, correlation analysis using the Pearson correlation coefficient, significant results if the value of p <0.05. Data were analyzed using SPSS version 17 for Windows.Results: Most of the respondents were males (67%), the mean of neonatal gestational age was 33 (± 3,2) weeks with the median neonatal age at lactate sampling being 24 (24-48) hours. The average age of the mother at delivery was 24 (21-40) years. The mean lactate level in critically ill neonatal patients admitted to the NICU was 3.2 (± 0,5) mmol / L. The mean SNAPPE II score on the subject was 32 (20-42). There was a significant positive correlation between the levels of lactate and the severity of the disease in critically ill neonates in the NICU assessed by SNAPPE II (r = 0.45; p = 0.004).Conclusion: Lactate levels has a moderate positive correlation with the severity of the disease in critically ill neonates in the NICU assessed by SNAPPE II
The suitability of sputum and blood culture in children with pneumonia at Sanglah General Hospital, Bali, Indonesia Ayu Setyorini Mestika Mayangsari; Ida Bagus Subanada; Putu Siadi Purniti; Wayan Agustini Selumbung
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.298 KB) | DOI: 10.15562/ism.v10i3.606

Abstract

Background: Pneumonia is one of the diseases in children with high morbidity, especially in children under 5 years old. In developing countries, the most common cause of pneumonia is bacteria. There is a newer method that gives a better reflection of the aetiology, which is the sputum examination. This study aims to determine the suitability of sputum and blood culture in children with pneumonia at Sanglah General Hospital, Bali.Methods: A cross-sectional study was conducted at Respirology Subdivision in Department of Child Health Sanglah Hospital from November 2016 until February 2017. A categorical comparative matching was carried out between 2 formula groups. The sputum culture and blood culture were obtained through Microbiology Laboratory at Sanglah General Hospital. Data were analysed using SPSS version 16 for Windows.Results: There were 50 children with pneumonia enrolled in this study. The children aged less than 1 years old were predominant (62%). There were a statistically systematic difference and only a fair agreement between blood and sputum culture (ĸ=0.257; p= 0.004). In a subject with positive sputum culture, 90.9% had a better outcome than the positive blood culture even though no statistically significant (RR=0.23; 95%CI: 0.15-22.53)Conclusion: There is suitability between the culture of sputum and blood cultures in children with pneumonia. Sputum culture has a higher probability to reveal the microorganism compared to blood cultures.
Hubungan Rasio Neutrofil Limfosit (RNL) terhadap kejadian relaps pada anak dengan sindrom nefrotik di RSUP Sanglah, Bali, Indonesia Wega Upendra Sindhughosa; Gusti Ayu Putu Nilawati; Ni Putu Siadi Purniti; Bagus Ngurah Putu Arhana; Ketut Ariawati; Putu Junara Putra
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (463.48 KB) | DOI: 10.15562/ism.v11i2.652

Abstract

Background: Nephrotic Syndrome is a disease whose cause is not fully known and has a high relapse rate. The lymphocyte neutrophil ratio is a marker of inflammation in patients with malignancy, infection, and coronary heart disease. This study aims to determine the relationship between Neutrophil Lymphocyte Ratio (NLR) and the occurrence of relapse nephrotic syndrome.Methods: This study was a retrospective analytic observational study with a cross-sectional approach to finding the relationship between increased NLR and the incidence of relapse in patients with nephrotic syndrome at SMF Children's Health Sciences Faculty of Medicine Universitas Udayana/Sanglah General Hospital. Data were taken from medical records of 45 respondents with episodes of relapse or remission from January 2018-January 2019. Data were analyzed using SPSS version 20 for Windows.Results: The results showed that most of the subjects were male (71.1%), aged 1-5 years (51.2%), and aged 4.00 ± 8.50 years in both the relapse and remission groups. However, the infection rate (66.7%) and medication adherence (75.0%) tended to be higher in the relapse group. The analysis of the ROC curve shows the cut-off point of NLR was 2.36 (AUC: 0.521), with a sensitivity of 71.1% and a specificity of 73.3%. There was a significant relationship between the NLR value and the incidence of relapsed nephrotic syndrome in multivariate analysis (adjusted OR: 4.53; 95% CI: 1.68 - 12.22; p = 0.003).Conclusion: This study shows that there is a relationship between an increase in RNL and the incidence of relapse in pediatric nephrotic syndrome patients at Sanglah General Hospital, Bali, Indonesia. Latar belakang: Sindrom Nefrotik merupakan salah satu penyakit yang penyebabnya belum sepenuhnya diketahui dan memiliki angka relaps yang tinggi. rasio neutrofil limfosit merupakan suatu pertanda inflamasi pada pasien yang mengalami keganasan, infeksi dan penyakit jantung koroner. Penelitian ini bertujuan untuk mengetahui hubungan Rasio Neutrofil Limfosit (RNL) dengan terjadinya sindrom nefrotik relaps.Metode: Penelitian ini merupakan penelitian retrospektig observasional analitik dengan pendekatan potong lintang untuk mencari hubungan peningkatan RNL terhadap kejadian relaps pada pasien sindrom nefrotik di SMF Ilmu Kesehatan Anak FK UNUD/Rumah Sakit Umum Pusat Sanglah. Data diambil dari rekam medik terhadap 45 responden dengan episode relaps maupun remisi dari Januari 2018-Januari 2019. Data dianalisis dengan SPSS versi 20 untuk Windows.Hasil: Hasil penelitian menunjukkan bahwa sebagian besar subyek adalah laki-laki (71,1%), berusia 1-5 tahun (51,2%), maupun berusia 4,00±8,50 tahun baik pada kelompok relaps maupun remisi. Akan tetapi angka infeksi (66,7%) maupun ketidak patuhan pengobatan (75,0%) cenderung lebih tinggi pada kelompok relaps. Analisa kurva ROC menunjukkan titik potong RNL sebesar 2,36 (AUC: 0,521) dengan sensitivitas 71,1% dan spesifisitas 73,3%. Terdapat hubungan bermakna antara nilai RNL dengan kejadian sindrom nefrotik relaps pada analisis multivariat (adjusted OR: 4,53; 95%IK: 1,68 – 12,22; p=0,003).Simpulan: Penelitian ini menunjukkan bahwa terdapat hubungan antara peningkatan RNL terhadap kejadian relaps pada penderita sindrom nefrotik anak di RSUP Sanglah, Bali, Indonesia
Occurence and risk factors of tuberculosis infection in orphanage children in Bali Clearesta, Kartika Eda; Mayangsari, Ayu Setyorini Mestika; Wati, Dyah Kanya; Purniti, Ni Putu Siadi; Suwarba, I Gusti Ngurah Made; Artana, I Wayan Dharma
Paediatrica Indonesiana Vol. 64 No. 2 (2024): March 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.2.2024.152-9

Abstract

Background Tuberculosis (TB) is an infectious disease that is still a common threat worldwide, especially in pediatric populations. TB transmission occurs particularly when the transmitter has no obvious manifestation of the disease. There is a higher incidence of TB infection in children than in the general population, especially in high risk populations such as children in orphanages. However, the incidence of TB infection in orphaned children in Indonesia, including Bali, is unknown. Objective To describe the incidence and risk factors for TB infection in children in orphanages in Bali. Methods This case-control study was conducted in 12 orphanages in Bali. Subjects were divided into a case group comprised of children with TB infection, and a control group comprised of those without TB infection. TB infection was diagnosed by positive tuberculin test without clinically confirmed TB. Results A total of 175 children were recruited as subjects. There were 49 (28.0%) children with TB infection. Bivariate analysis revealed significant associations between density, humidity, ventilation/room area ratio, and area of ??origin with TB infection. Multivariate analysis showed that ventilation/room area ratio and room humidity of ?73% were independently positive correlated with TB infection. Natural lighting and BCG scar were not significantly different between groups. Conclusion The occurence of TB infection in children residing in orphanages in Bali is high (28%). The risk factors identified independently are lower ventilation and higher room humidity.
Co-Authors AA Raka Karsana Adianta, I Ketut Anak Agung Ngurah Ketut Putra Widnyana Artawan Artawan Ayu Setyorini Mestika Mayangsari Bagus Ngurah Putu Arhana BNP Arhana Budastra I Nyoman Clearesta, Kartika Eda Dewa Ayu Dini Primashanti Dewi Aryawati Utami DIAN SAVITRI Dyah Kanya Wati Gusti Ayu Putu Nilawati I Gede Deden Susma Sugara I Gede Epi Paramarta I Gusti Agung Trisna Windiani I Gusti Ayu Putu Eka Pratiwi I Gusti Lanang Sidiartha I Gusti Ngurah Made Suwarba I Komang Kari I Kompiang Gede Suandi I Made Arimbawa I Made Kardana I Nyoman Supadma I Putu Gede Karyana I Wayan Dharma Artana I Wayan Dharma Artana, I Wayan Dharma I Wayan Gustawan Ida Bagus Subanada Ida Bagus Subanda Ida Sri Iswari Irene Irene Julitasari S Ketut Ariawati Ketut Dewi Kumara Wati Ketut Putu Yasa Ketut Suarta Komang Ayu Witarini Luh Gde Ayu Pramitha Dewi Made Rismawan Made Sukmawati Made Supartha Maria Priskila Ni Made Adi Tarini Ni Putu Sucita Wahyu Dewi Novilia Sjafri Bachtiar Putu Astawa Putu Junara Putra Putu Meitri Nirmala Utami Putu Nandika Wintari Rini Mulia Sari Roni Naning Roni Naning Rosalia Theodosia Daten Beyeng Soetjiningsih Soetjiningsih Sumadiono Sumadiono Vidya Lakshmi Anbhuselvam Wayan Agustini Selumbung Wega Upendra Sindhughosa