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Hubungan Antara Usia dan Jenis Kelamin dengan Kejadian Multidrugs-Resistant Tuberculosis (MDR-TB) di Rumah Sakit Paru Dr. M. Goenawan (RSPG) Cisarua Bogor Siti Fatimah Az'zahra; Nurhayati, Eka; Hartati, Julia; Sawitri, Neni
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.12431

Abstract

Abstract. Tuberculosis (TB) is a chronic infectious disease caused by Myobacterium tuberculosis. TB is considered the second top killer infectious disease and is the 13th cause of death worldwide. Long treatment and uncertain times of onset pose a challenge to compliance in the TB treatment process. Non-adherence to treatment results in multi-drug-resistant (MDR-TB). This condition occurs when TB patients experience resistance to the drugs isoniazid (H) and rifampicin (R), which are anti-tuberculosis drugs (OAT). This research is a cross sectional study conducted at RSPG Cisarua Bogor on 299 patients. Data was obtained from medical records in the form of age and gender characteristics. Data were analyzed using univariate and bivariate tests and then carried out the Chi-Square test. The results of this study show that the average age of MDR-TB patients is 39 years and more males. The Chi-Square test shows an age p-value of 0.014 (<0.05) and a gender p-value of 0.605 (>0.05). MDR-TB patients are more common in male than female, but there is no significant relationship because the location of the rpOB gene and KatG gene which are mutated are in bacteria, not humans. MDR-TB is more vulnerable in productive age because high productivity can cause treatment errors that result in MDR-TB. It was found from this study that there was a relationship between age and the incidence of MDR-TB and there was no relationship betweensex and the incidence of MDR-TB. Abstrak. Tuberkulosis (TB) merupakan penyakit infeksi menular kronis yang disebabkan oleh Myobacterium tuberculosis. TB dianggap sebagai penyakit infeksi pembunuh teratas kedua dan menjadi penyebab kematian ke-13 di seluruh dunia. Pengobatan yang lama dan onset waktunya tidak pasti menjadi tantangan kepatuhan dalam proses pengobatan TB. Ketidakpatuhan pengobatan mengakibatkan terjadinya multidrugs-resistant tuberculosis (MDR-TB). Kondisi ini terjadi ketika pasien TB mengalami resistensi terhadap obat isoniazid (H) dan rifampisin (R) yang merupakan obat anti-tuberkulosis (OAT). Penelitian ini merupakan penelitian cross sectional yang dilakukan di RSPG Cisarua Bogor pada 299 pasien. Data diperoleh dari rekam medis berupa karakteristik usia dan jenis kelamin. Data dianalisis dengan uji univariat dan bivariate lalu dilakukan uji Chi-Square. Hasil penelitian ini menunjukkan rerata usia pasien MDR-TB adalah 39 tahun dan lebih banyak pada laki – laki. Uji Chi-Square menunjukkan p-value usia sebesar 0,014 (<0,05) dan p-value jenis kelamin sebesar 0,605 (>0,05). Pasien MDR-TB lebih banyak terjadi pada laki – laki dibandingkan perempuan namun tidak terdapat hubungan bermakna karena letak gen rpOB dan gen KatG yang mengalami mutasi terletak pada bakteri bukan pada manusia. MDR-TB lebih rentan pada usia produktif karena produktivitas yang tinggi dapat menyebabkan kelalaian pengobatan yang mengakibatkan MDR-TB. Didapatkan dari penelitian ini bahwa terdapat hubungan antara usia dengan kejadian MDR-TB dan tidak terdapat hubungan antara jenis kelamin dengan kejadian MDR-TB.
Improving Patients’ and Families’ Knowledge of Psychosocial Hazards through Education at Manar Medika Clinic Febriani, Nelly; Fadhilah, Nur Syafrina; Amma, Salsabila Shafa Muradi; Hidayat, Wahid; Afiati, Farida; Humaira, Khansa; N, Nurlaila; Roselowati, Yessy Rahma; A, Atikah; Putri, Nafisya Nur Adiba Purnomo; Hartati, Julia
Nanggroe: Jurnal Pengabdian Cendikia Vol 4, No 8 (2025): November
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.17608743

Abstract

Psychosocial hazards are a significant challenge in primary healthcare services because they can affect the mental well-being of patients and their families. Emotional strain resulting from chronic illness, treatment uncertainty, and changes in family roles often leads to stress, anxiety, and emotional exhaustion. A lack of understanding regarding psychosocial factors frequently results in delayed mental health management, ultimately impacting patients’ quality of life. This community service activity aimed to enhance patients’ and families’ knowledge of psychosocial hazards through participatory education conducted at Manar Medika Clinic, Depok. The method used was a quantitative approach with a cross-sectional design. Education was delivered through interactive lectures, group discussions, and demonstrations involving ten respondents selected through total sampling. Evaluation was conducted by measuring knowledge levels before and after the activity using a structured questionnaire to assess knowledge improvement following the intervention. The results showed a significant increase in knowledge. The participants’ average score rose from 46 to 98, with a 52-point difference. Before the educational session, most respondents had low knowledge levels (70%); however, after the intervention, all participants (100%) reached the “good” category. These findings indicate that the educational activity was effective in improving participants’ understanding of psychosocial hazards, raising awareness of the importance of emotional support, and helping patients and families manage stress more adaptively.
Improving Patients’ and Families’ Knowledge of Psychosocial Hazards through Education at Manar Medika Clinic Febriani, Nelly; Fadhilah, Nur Syafrina; Amma, Salsabila Shafa Muradi; Hidayat, Wahid; Afiati, Farida; Humaira, Khansa; N, Nurlaila; Roselowati, Yessy Rahma; A, Atikah; Putri, Nafisya Nur Adiba Purnomo; Hartati, Julia
Nanggroe: Jurnal Pengabdian Cendikia Vol 4, No 8 (2025): November
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.17608743

Abstract

Psychosocial hazards are a significant challenge in primary healthcare services because they can affect the mental well-being of patients and their families. Emotional strain resulting from chronic illness, treatment uncertainty, and changes in family roles often leads to stress, anxiety, and emotional exhaustion. A lack of understanding regarding psychosocial factors frequently results in delayed mental health management, ultimately impacting patients’ quality of life. This community service activity aimed to enhance patients’ and families’ knowledge of psychosocial hazards through participatory education conducted at Manar Medika Clinic, Depok. The method used was a quantitative approach with a cross-sectional design. Education was delivered through interactive lectures, group discussions, and demonstrations involving ten respondents selected through total sampling. Evaluation was conducted by measuring knowledge levels before and after the activity using a structured questionnaire to assess knowledge improvement following the intervention. The results showed a significant increase in knowledge. The participants’ average score rose from 46 to 98, with a 52-point difference. Before the educational session, most respondents had low knowledge levels (70%); however, after the intervention, all participants (100%) reached the “good” category. These findings indicate that the educational activity was effective in improving participants’ understanding of psychosocial hazards, raising awareness of the importance of emotional support, and helping patients and families manage stress more adaptively.