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THE EFFECT OF MACERATION METHOD AND SOXHLETATION METHOD ON TOTAL PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF KIRINYUH (Chromolaena odorata (L.) R.M.King & H.Rob) LEAF Renatha Audya Larasati; Nastiti Utami; Novena Yety Lindawati
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.889

This study evaluated kirinyuh leaf extract as a natural antioxidant using Soxhlet extraction and maceration extraction methods. Dried leaves of kirinyuh were extracted with 96% ethanol. The total phenolic content was measured spectrophotometrically according to the Folin Ciocalteu method, calculated as gallic acid equivalent (GAE), while the antioxidant activity was measured using ABTS. The results of the phytochemical test of kirinyuh leaf extract using maceration (EKM) and Soxhletation (EKS) methods revealed alkaloids, flavonoids, saponins, steroids, and tannins. The total phenolic content of EKM was 39.85 Â± 0.20 mgGAE/gram and EKS was 46.95 Â± 0.15 mgGAE/gram extract. Antioxidant activity in the form of IC50 EKM was 46.10 Â± 0.09 mg/L and EKS was 45.27 Â± 0.07 mg/L, both of them have a very strong category. There were significant differences in the total phenolic content and antioxidant activity of the ethanol extract of the Kirinyuh leaf using maceration and soxhletation methods based on the results of the T-test. Keywords: Kirinyuh, Eupatorium odoratum, ABTS, phenolics, antioxidant.

Alternatif Pengobatan Hipertensi dalam Program Pengabdian Masyarakat STIKES Nasional di Desa Kwarasan, Grogol, Sukoharjo Novena Yety Lindawati; Danie Nugroho; Geffa Yusinda Ardanaputri; Maria Oktafiani Ari Saputri; Mohollana Mohollana; Rika Triastuti; Sari Murdianningsih
Jurnal Surya Masyarakat Vol 6, No 1 (2023): November 2023
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.6.1.2023.98-103

Hypertension is an increase in systolic blood pressure of more than 140 mmHg and diastolic blood pressure of more than 90 mmHg on two measurements with an interval of five minutes in a state of sufficient rest, calm. Treatment of hypertension can use medicinal plants, namely bay leaves and soursop leaves. Bay leaves and soursop leaves have antioxidant activity that can counteract free radicals so that they can lower blood pressure, while bay leaves themselves contain flavonoids that can reduce the risk of cardiovascular disease. This activity program uses the method of giving local seminars and workshops directly to the PKK group in Kwarasan Village, Grogol District, Sukoharjo Regency. The results of real work lecture program showed an increase in participants' knowledge which was evaluated through an average increase in the pretest score from 86 to 94 during the posttest as well as an increase in the skills of participants in workshop activities.

THE EFFECT OF MACERATION METHOD AND SOXHLETATION METHOD ON TOTAL PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF KIRINYUH (Chromolaena odorata (L.) R.M.King & H.Rob) LEAF Renatha Audya Larasati; Nastiti Utami; Novena Yety Lindawati
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.889

This study evaluated kirinyuh leaf extract as a natural antioxidant using Soxhlet extraction and maceration extraction methods. Dried leaves of kirinyuh were extracted with 96% ethanol. The total phenolic content was measured spectrophotometrically according to the Folin Ciocalteu method, calculated as gallic acid equivalent (GAE), while the antioxidant activity was measured using ABTS. The results of the phytochemical test of kirinyuh leaf extract using maceration (EKM) and Soxhletation (EKS) methods revealed alkaloids, flavonoids, saponins, steroids, and tannins. The total phenolic content of EKM was 39.85 ± 0.20 mgGAE/gram and EKS was 46.95 ± 0.15 mgGAE/gram extract. Antioxidant activity in the form of IC50 EKM was 46.10 ± 0.09 mg/L and EKS was 45.27 ± 0.07 mg/L, both of them have a very strong category. There were significant differences in the total phenolic content and antioxidant activity of the ethanol extract of the Kirinyuh leaf using maceration and soxhletation methods based on the results of the T-test. Keywords: Kirinyuh, Eupatorium odoratum, ABTS, phenolics, antioxidant.

Pengembangan dan Pengolahan Ikan Tongkol (Euthynnus affinis) Dengan Kombinasi Sayuran Lokal yang Berpotensi Mencegah dan Mengendalikan Stunting pada Masyarakat Desa Bakipandeyan Novena Yety Lindawati; Ovikariani Ovikariani; Luthfi Nur Athifa; Putu Tia Angelia; Rinda Susan Yuliyani; Arfi Delasafira
Jurnal Surya Masyarakat Vol 7, No 1 (2024): November 2024
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.7.1.2024.81-87

Stunting is the condition of toddlers who experience failure to grow or have a body condition that is shorter than their age standard due to malnutrition, inadequate recurrent infections in the first 1,000 days of life. Bakipandeyan Village, Baki, Sukoharjo is one of the assisted villages that pays attention to the prevention and control of stunting. This encourages the holding of community service activities aimed at preventing and controlling stunting in children aged 0-24 months. This activity program uses seminar and workshop methods directly to mothers with children aged 0-24 months, health workers, and PKK cadres by considering the status of stunting and malnutrition in the Bakipandeyan village area, Baki, Sukoharjo. The results of community service showed an increase in participants' knowledge which was evaluated through an average increase in pretest scores from 79.77 to 93.86 at posttest as well as an increase in participants' skills in workshop activities. The results of the partner satisfaction questionnaire showed that people who gave good to very good appreciation reached 95%, so this activity was appropriate, satisfying and accepted by the people of Bakipandeyan Village, Baki, Sukoharjo.

Alternatif Pengobatan Hipertensi dalam Program Pengabdian Masyarakat STIKES Nasional di Desa Kwarasan, Grogol, Sukoharjo Novena Yety Lindawati; Danie Nugroho; Geffa Yusinda Ardanaputri; Maria Oktafiani Ari Saputri; Mohollana Mohollana; Rika Triastuti; Sari Murdianningsih
Jurnal Surya Masyarakat Vol 6, No 1 (2023): November 2023
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.6.1.2023.98-103

Hypertension is an increase in systolic blood pressure of more than 140 mmHg and diastolic blood pressure of more than 90 mmHg on two measurements with an interval of five minutes in a state of sufficient rest, calm. Treatment of hypertension can use medicinal plants, namely bay leaves and soursop leaves. Bay leaves and soursop leaves have antioxidant activity that can counteract free radicals so that they can lower blood pressure, while bay leaves themselves contain flavonoids that can reduce the risk of cardiovascular disease. This activity program uses the method of giving local seminars and workshops directly to the PKK group in Kwarasan Village, Grogol District, Sukoharjo Regency. The results of real work lecture program showed an increase in participants' knowledge which was evaluated through an average increase in the pretest score from 86 to 94 during the posttest as well as an increase in the skills of participants in workshop activities.

Pelatihan Pembuatan Sediaan Teh dari Bunga Rosella Ungu (Hibiscus sabdariffa L.) sebagai Antioksidan Alami di Desa Pondok Novena Yety Lindawati; Nastiti Utami; Anita Mursiany; Disvana Mardiningtyas; Imelda Cantika Putri; Maria Neheria Kusuma; Oktavia Kharismawati Cahya Rahmadani
Jurnal Surya Masyarakat Vol 8, No 2 (2026): Mei 2026
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.8.2.2026.318-325

Purple roselle (Hibiscus sabdariffa L.) is a medicinal plant rich in anthocyanins and flavonoids, which function as natural antioxidants capable of neutralizing free radicals and preventing degenerative diseases. However, the community of Desa Pondok continues to use purple roselle sparingly, both for its health benefits and its economic potential. This community service program aimed to improve the knowledge and skills of PKK cadres and health volunteers in Desa Pondok in processing purple roselle into functional herbal tea. The program was conducted in four stages: a health education session on the benefits of roselle; training in the preparation of simplisia; a herbal tea-making workshop; and the introduction of simple digital marketing strategies. Evaluation was conducted through pre- and posttests and participant satisfaction questionnaires. The results showed a significant improvement in participants’ understanding, with the average pretest score of 57 rising to 96.67 in the posttest (p=0.000). Additionally, the level of community satisfaction with the overall implementation of the activity reached 97.88%, with an average satisfaction index of 4.89, indicating high satisfaction. The training not only equipped participants with technical skills but also opened opportunities for developing local herbal-based businesses. This activity proved effective in promoting the use of local natural resources and increasing community awareness of the importance of consuming natural antioxidants.

Pengembangan dan Pengolahan Ikan Tongkol (Euthynnus affinis) Dengan Kombinasi Sayuran Lokal yang Berpotensi Mencegah dan Mengendalikan Stunting pada Masyarakat Desa Bakipandeyan Novena Yety Lindawati; Ovikariani Ovikariani; Luthfi Nur Athifa; Putu Tia Angelia; Rinda Susan Yuliyani; Arfi Delasafira
Jurnal Surya Masyarakat Vol 7, No 1 (2024): November 2024
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.7.1.2024.81-87

Stunting is the condition of toddlers who experience failure to grow or have a body condition that is shorter than their age standard due to malnutrition, inadequate recurrent infections in the first 1,000 days of life. Bakipandeyan Village, Baki, Sukoharjo is one of the assisted villages that pays attention to the prevention and control of stunting. This encourages the holding of community service activities aimed at preventing and controlling stunting in children aged 0-24 months. This activity program uses seminar and workshop methods directly to mothers with children aged 0-24 months, health workers, and PKK cadres by considering the status of stunting and malnutrition in the Bakipandeyan village area, Baki, Sukoharjo. The results of community service showed an increase in participants' knowledge which was evaluated through an average increase in pretest scores from 79.77 to 93.86 at posttest as well as an increase in participants' skills in workshop activities. The results of the partner satisfaction questionnaire showed that people who gave good to very good appreciation reached 95%, so this activity was appropriate, satisfying and accepted by the people of Bakipandeyan Village, Baki, Sukoharjo.

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