Erial Bahar
Department of Anatomy, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia

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Accuracy of Neutrophil/Lymphocyte Ratio as Predictor of Neoadjuvant Chemotherapy Response in Locally Advanced Breast Cancer at Dr. Mohammad Hoesin General Hospital Palembang M. Aprizal Putera; Mulawan Umar; Erial Bahar
Sriwijaya Journal of Surgery Vol. 4 No. 1 (2021): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v4i1.56

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Introduction: Breast cancer is one of the most common neoplasm occurs in women. Neoadjuvant Chemotherapy (NACT) is widely used in Locally Advanced Breast Cancer (LABC) and Inflammatory Breast Cancer (IBC), to reduce tumor size (down-sizing), and further allowing breast-conserving surgery to be performed. Accurate markers are needed to prevent impractical chemotherapy that allows patients to receive definitive surgery in a timely manner. Previous study showed neutrophil/lymphocyte ratio (NLR) was superior in predicting long-term outcomes over PLR. This study aims to evaluate the relationship between the NLR value and neoadjuvant chemotherapy response in patients with locally advanced breast cancer at Dr. Mohammad Hoesin General Hospital Palembang. Methods: This study is a prognostic test of the NLR accuracy to predict the response of neoadjuvant chemotherapy in patients with locally advanced breast cancer. The study included 113 patients as study subjects. Results: The obtained NLR cut off point value was ≤ 2.92 with an area under the ROC curve (AUC) of 92.2%. The diagnostic measures of the NLR prognostic test had sensitivity of 93%, specificity of 93%, Positive Predictive Value of 97%, Negative Predictive Value of 82%, and accuracy of 93%. There is a significant relationship between NLR and chemotherapy response in patients with locally advanced breast cancer (p = 0.000). Conclusion: There is a significant relationship between NLTR and chemotherapy response. NLR can be used as a predictor of neoadjuvant chemotherapy response with a good degree of accuracy.
Correlation between APACHE II Score on Mortality Severe Head Injury Patients in the Educational Room of Dr. Mohammad Hoesin General Hospital Palembang in 2019-2020 Anggi Ciptawan; Trijoso Permono; Erial Bahar
Sriwijaya Journal of Surgery Vol. 5 No. 1 (2022): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v5i1.70

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tissue due to trauma. Severe head injuries account for about 10% of the total head injuries. In addition to death caused by severe head injury itself, head injury patients are susceptible to complications that can occur while the patient is hospitalized. The purpose of this study was to determine the correlation between the APACHE II Score on the mortality of severe head injury patients who were treated in the GICU room, Dr. Mohammad Hoesin Palembang. This type of research is a quantitative research using a retrospective analytical study survey design. Between group variables are unpaired because no matching is done. The research sample is 30 respondents. Results of analysis in this study, after statistical testing using the Chi Square test, p value < 0. 002 was obtained which clarified that there was a relationship between APACHE II Score and mortality in respondents with severe head injuries who were treated in the GICU, Dr. Mohammad Hoesin Palembang. Severe head injury in the GICU room, Dr. Mohammad Hoesin Palembang (p=0.002). The higher the patient's APACHE II score, the more likely the patient to leave the GICU dead. From a total of 30 respondents who were treated in the GICU room, the highest APACHE II score was 28 and the lowest was 3 the more likely the patient to leave the GICU dead. From a total of 30 respondents who were treated in the GICU room, the highest APACHE II score was 28 and the lowest was 3 the more likely the patient to leave the GICU dead. From a total of 30 respondents who were treated in the GICU room, the highest APACHE II score was 28 and the lowest was 3.
Factors Associated with Free Flap Viability at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Mufida Muzakkie; Argo Ismoyo; Erial Bahar
Sriwijaya Journal of Surgery Vol. 6 No. 1 (2023): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v6i1.84

Abstract

Introduction: A free flap is part of reconstructive surgery. This technique takes tissue or bone flaps along with their original vascular supply and performs microvascular anastomosis of the pedicle arteries and veins at the recipient site. Several risk factors that influence the occurrence of flap failure are still a major concern, such as age, gender, defect size, duration of surgery, length of tissue ischemic time, nutritional status, etc. This is further associated with higher morbidity, the potential for flap failure, higher costs, and increased length of stay in the hospital. This study aimed to determine the factors associated with free flap viability at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Methods: Cross-sectional analytic observational study. A total of 33 research subjects participated in this study. Observation of risk factors was carried out using SPSS univariate and bivariate. Results: Gender and ischemic time factors are related to free flap viability. Male gender and ischemic time < 60 minutes increase the success of free flap viability. Conclusion: Gender and length of ischemic time are associated with free flap viability at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
Reflux Symptom Index And Reflux Finding Score Correlation With Quality Of Life Of Laryngopharyngeal Reflux Patients Lisa Apri Yanti; Rama Mandela; Erial Bahar
Biomedical Journal of Indonesia Vol. 8 No. 3 (2022): Vol 8, No 3, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v8i3.139

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Introduction. Laryngopharyngeal reflux (LPR) usually occurs due to the effects of reflux on the gloves and vocal cords. Symptoms range from more common symptoms such as hoarseness,  globus sensations, and a feeling of getting stuck in the throat to less common symptoms such as heartburn and regurgitation. Symptoms common to LPR are not specific and may be related to other diseases. In other words, it is difficult to diagnose LPR based solely on symptoms. Belafsky et al in 2001 and 2002 developed the Reflux Symptom Index (RSI) and Reflux Finding Score (RFS) to assist in the diagnosis of LPR. Health-related quality of life Health-Related Quality of Life (HRQOL) in LPR patients have a negative impact on psychological status, social functioning, and quality of life. Symptoms of reflux appear to be a major contributor to the decline in quality of life. LPR patients have a significant impact on the mental component of their HRQO. Methods. Descriptive research with a correlation test design, conducted at RSUP Dr. Mohammad Hoesin Palembang on 22 samples of LPR patients who were treated at ENTKL polyclinics, IGD, or consulted from other departments in July-August 2022. Results. The majority of the study were women (81.85%) with dominant in the age group of 31-45 years (45.5%) with an average age of 42.23±11.88 years and a range of 19-66 years. There is a strong correlation between RSI and RFS with quality of life (r = 0.615; p = 0.016, r = 0.635; p = 0.028, respectively). Conclusion. RSI and RFS are significantly related to the quality of life of the sample so the treatment is recommended to also focus on the LPR only but also the mental health aspects.
Comparison Of Handicap Inventory Tinnitus Scores Before and After Intra Tympanic Steroid Injection In Tinnitus Patients Amir Hamzah; Erial Bahar; Ahmad Hifni; Abla Ghanie
Biomedical Journal of Indonesia Vol. 8 No. 3 (2022): Vol 8, No 3, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v8i3.148

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Introduction. Tinnitus is a symptom in the form of a conscious perception of sound that is not produced by a sound source outside the body. Patients with tinnitus often have complaints of quality of life, with some situations of extreme anxiety, depression, and life changes. The Tinnitus Handicap Inventory (THI) is a valid questionnaire to be associated with patients associated with tinnitus. The Tinnitus Research Initiative (TRI), an international academic organization founded in 2006, recommends the use of THI for the evaluation of tinnitus defects and therapeutic effects. Therefore, a THI assessment is needed at RSUP Dr. Mohammad Hoesin Palembang as a result of therapy. Methods. This research using a design that aims to determine the comparison of THI scores before and after intratympanic injection of corticosteroids in 18 samples at RSUP Dr. Mohammad Hoesin Palembang. Results. The average age of the sample was 57 (23-66) years and the number of men and women were the same, namely 9 (50%) samples. Most of the samples had problems in unilateral ears by 14 (77,8%) samples. The average THI before intratympanic steroid injection was 37 (12-72) and after injection was 20 (4-80). Wilcoxon test results showed significant changes between before and after intratympanic steroid injection. Conclusion. There was a significant improvement in THI scores after intratympanic steroid injection.
Comparison of Oropharyngeal Microbial Pattern Based on Nasogastric Tube (NGT) Use in Dr. Mohammad Hoesin Hospital Puspa Zuleika; Riezki Indrina Pratiwi; Erial Bahar
Biomedical Journal of Indonesia Vol. 8 No. 1 (2022): Vol 8, No 1, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/BJI.v8i1.137

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Introduction. A Nasogastric Tube (NGT) is a flexible tube inserted into the stomach through the nose (nares) to preserve nutritional support. The use of NGT is claimed to increase the risk of pathogenic bacteria colonization due to stagnation, ultimately worsening the patient's outcome. Proper identification of bacterial patterns is required as colonization grows to avoid further complications. This study aims to compare oropharyngeal microorganism patterns in patients with NGT to those without NGT at Dr. Mohammad Hoesin Palembang. Methods. A cross-sectional observational study was used. From September 2022 to October 2022, data were collected using primary data from interviews (research questionnaires) and oropharyngeal swab results (bacterial culture) in 42 patients undergoing treatment at Dr. RSUP. Mohammad Hoesin Palembang's ENT department. Results. Positive colonization was found in all patients with NGT (100%) and 90.47% in the group without NGT. P. aeruginosa was the most common pathogen in the NGT group (47.62%). The use of NGT, body weight, height, and body mass index were significant risk factors in the incidence of P. aeruginosa colonization (p=0,012). Conclusion. There is a significant difference in P. aeruginosa colonization between NGT and non-NGT users. NGT use is the most important driving factors of colonization development. However, these findings were not found in colonization in general or specific bacteria categories.
Correlation Between Pharyngeal Residue With Food Consistency In Neurogenic Dysphagia Patients Using FEES At RSMH Palembang Puspa Zuleika; Apriandini Mirdasari Putri; Erial Bahar
Biomedical Journal of Indonesia Vol. 8 No. 2 (2022): Vol 8, No 2, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/BJI.v8i2.140

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Introduction. Disorders of swallowing process starting from preparation and bolus transportation called dysphagia. Supporting examination for dysphagia is Fiberoptic Endoscopic Examination of Swallowing (FEES). Aims to determine correlation between pharyngeal residues and food consistency in neurogenic dysphagia patients. Methods. Observational study using cross-sectional design. Data was collected from medical records of 32 patients with neurological disorders complaints swallowing who underwent FEES examination at RSMH January 2021 to July 2022. Statistical analysis using SPSS 24.0. Results. Participants was 32 patients with neurogenic dysphagia with the most male sex, 19 patients (59.4%), the most age group ≥  60 years, 17 patients (53.1%). 18 patients had comorbidities (59.4%) with the highest number hypertension 15 patients (50%). Highest leakage in water group with 9 (37.5%) out of 24 experiments while in the filtered porridge group 12 (37.5%) out of 32 experiments. Highest penetration occurred in water 41.7% and filtered porridge 40.9%. Highest aspiration in filtered porridge was 34.4%. Somers’ d correlation test obtained p value 0.028, there was significant correlation between types of food and degree of residual valleculas, and the strength was very weak (ra value: 0.138). The piriform sinus region, obtained p value 0.014, there was significant correlation between type of food and degree of residual piriform sinus and the value of the strength also very weak (ra 0.153). Conclusion. There is significant correlation between types of food and degree of residual valleculas and piriform sinuses. As food resistance increases, the residual degree of valleculas and piriform sinuses will also increase.
RESULTS OF INTRAVENOUS ALINAMIN AND ALCOHOL EXAMINATION RESULTS IN PATIENTS COMPLAINTS OF SNACTING DISORDERS AT RSMH PALEMBANG Yoan Levia Magdi; Guntur Bayu Bima Pratama; Erial Bahar
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 10 No. 2 (2023): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v10i2.349

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Bau adalah zat kimia yang tercampur di udara yang dirasakan manusia dengan indra penciumannya. Hilangnya penciuman atau hilangnya penciuman menjadi hal yang sangat penting dalam beberapa tahun terakhir. Saat ini penelitian mengenai bau sangat menarik karena dapat mengetahui jenis bau, serta fungsi penciuman. Pemeriksaan tes penciuman melalui infus dan tes penciuman alkohol merupakan salah satu pemeriksaan gold standard yang dapat dilakukan untuk mengetahui jenis gangguan penciuman. Untuk mengetahui kesesuaian hasil pemeriksaan penciuman alinamin intravena dengan pemeriksaan penciuman alkohol pada pasien gangguan penciuman di RSMH Palembang. Penelitian observasional dan analitik menggunakan metode cross sectional. Pengumpulan data dilakukan dengan menggunakan rekam medis RSUP Dr. Mohammad Hoesin Palembang periode Oktober 2022 sampai Januari 2023. Data dianalisis dengan IBM SPSS 25. Pada penelitian ini terdapat 49 pasien dengan keluhan gangguan penciuman ke bagian THTBKL. RSUP Dr. Mohammad Hoesin Palembang. Rerata usia penelitian adalah 33 tahun dengan populasi paling rentan berusia <20 tahun (26,5%). Dengan mayoritas berjenis kelamin perempuan (57,1%). Sedangkan sebagian besar pekerjanya sebagian besar adalah pelajar (26,5%) dan mengeluhkan gangguan bau secara bertahap (91,8%). Pasien yang datang dengan keluhan gangguan penciuman terbanyak adalah pasien dengan massa sinonasal (53,1%). Korelasi antara uji alinamin intravena dengan penciuman alkohol dengan menggunakan uji korelasi Spearman menunjukkan korelasi yang sangat kuat (r=0,908) dan pada uji kesesuaian menggunakan Cohen’s kappa diperoleh nilai sebesar 1,000 yang berarti tercapai kesepakatan sempurna antara kedua uji tersebut. Terdapat kesesuaian hasil pemeriksaan antara tes penciuman alinamin dengan tes penciuman alkohol pada pasien dengan keluhan gangguan penciuman.
Only the Boey Score Discriminates In-Hospital Mortality After Gastric Perforation: A STARD-Compliant Comparison with the Jabalpur Score Samuel Bertua Halomoan Manurung; Efman EU Manawan; Erial Bahar
Sriwijaya Journal of Surgery Vol. 9 No. 2 (2026): Sriwijaya Journal of Surgery
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v9i2.158

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Background: Gastric perforation remains a highly lethal surgical emergency, and competing preoperative mortality scores have not been compared directly in an Indonesian cohort. Objective: To compare the discrimination, calibration, and clinical utility of the Boey and Jabalpur scores for in-hospital mortality after emergency surgery for gastric perforation. Methods: This retrospective diagnostic-accuracy study, reported according to STARD 2015, included 55 consecutive adults who underwent emergency laparotomy for non-traumatic gastric perforation at a tertiary referral centre between January 2023 and September 2025. Both scores were evaluated against in-hospital death. Analyses included areas under the receiver operating characteristic curve, operating characteristics, calibration, and decision-curve analysis; quantities not identifiable from the aggregate source output were bounded rather than estimated. Result: Twenty-nine patients (52.7%) died in hospital. The Boey score discriminated mortality (AUC 0.747, 95% CI 0.630–0.863), whereas the Jabalpur score did not (AUC 0.623, 95% CI 0.470–0.777; p = 0.118; power 34.1%). The AUC difference was 0.123, but its variance was not identifiable. At the optimal cut-offs, Boey ≥2 yielded 58.6% sensitivity and 73.1% specificity, while Jabalpur ≥10 yielded 69.0% sensitivity and 61.5% specificity. The published Boey risk table underpredicted mortality (observed-to-expected ratio 1.70), and decision-curve benefit was limited. Conclusion: Only the Boey score separated survivors from decedents in this cohort. Formal superiority over the Jabalpur score remains unresolved, and the published Boey risk estimates require local recalibration before individual clinical use.