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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Majalah Kedokteran Sriwijaya Journal of General Procedural Dermatology and Venereology Indonesia SRIWIJAYA JOURNAL OF MEDICINE Bioscientia Medicina : Journal of Biomedicine and Translational Research Bali Dermatology and Venereology Journal Jurnal Pengabdian Masyarakat: Humanity and Medicine Bioscientia Medicina : Journal of Biomedicine and Translational Research Media Dermato-Venereologica Indonesiana Journal of General-Procedural Dermatology & Venereology Indonesia Bali Dermatology Venereology and Aesthetic Journal
Yulia Farida Yahya
Dermatology And Venereology Department, Faculty Of Medicine Universitas Sriwijaya. Palembang. Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

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Efficacy of 20% urea cream on uremic pruritus with uremic xerosis in chronic renal failure patients undergoing hemodialysis Yulia Farida Yahya; Nina Roiana; Rosi Andarina; Suprapti Suprapti; Irsan Saleh
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 30 No. 1 (2018): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (462.749 KB) | DOI: 10.20473/bikk.V30.1.2018.1-9

Abstract

Background: Uremic pruritus (UP) is the most common symptoms in patients with chronic renal failure (CRF) undergoing hemodialysis (HD). It is a chronic itch sensation of the skin, with the most frequent clinical manifestation being xerosis, which is difficult to treat. There is a significant relationship between UP and moderate to severe uremic xerosis (UX) in CRF patients undergoing HD. This condition could affect the quality of life and increase the risk of morbidity and mortality. The causes of UP with xerosis are still unclear, however it is evident that there is a disruption of skin barrier function. A 20% urea with the base materials cream consisting sodium pidolat sodium lactate (NaPCA) and vegetable oils that act as a natural moisturizing factor (NMF) can improve the skin barrier function by increasing skin hydration, reducing transepidermal water loss (TEWL) will result in the improvement of  UP with UX.  
Co-Authors Adi Agung Anantawijaya Daryogo Antonius, Cayadi Sidarta aryani, Inda astri Aurelia Stephanie Candra, Nofilia Citra Cyntya Sari Sovianti Damai Trilisnawati Damai Trislinawati Daryago, Adi Agung Anantawijaya Deddy Deddy Diba, Sarah Dimas Ega Wijaya Putra Dwi Handayani Emirzon, M. Afif Baskara Erial Bahar, Erial Fantoni, Odelia Jovita Jusuf Fifa Argentina Findrapase, Riri Puspa Putri Fitriani Fitriani Fitriani Garfendo, Grady Hari Darmawan Husan, Nopriyati Iche Andriyani Liberty, Iche Andriyani Ika Kartika Inda Astri Inda Astri Aryani Indah Astri Aryani Irsan Saleh Jatmiko, Pandu Haryo Kartowigno, Soenarto Kiki Septiafni Muhammad Irsan Saleh Mutia Devi Mutia Devi Nabila, Dewa Ayu Bulan Neubrina Raesuky Sukamto Nina Roiana Nina Roiana Nopriyati Nopriyati, Nopriyati Nugroho, Suroso Adi Nur Riviati, Nur Octyvani Vani Purwoko, Izazi Hari Radema A Pranata Radema Maradom Rahmadini, Meirina Rosi Andarina Rusmawardiana Rusmawardiana, Rusmawardiana Saputra, M. Akip Riyan Sarah Diba Sari, Zahra Ayu Lukita Shalini Nadarajah Soenarto Kartowigno Soenarto Kartowigno Stephanie, Aurelia Suprapti Suprapti Thaha, Mohammad Athuf Tiar Marina Toruan, Theresia L Toruan, Theresia Lumban Trilisnawati, Damai Widyastuti Yuli Kurniawati, Yuli Zahra Ayu Lukita Sari