Tjokorda Gde Dalem Pemayun
Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Diponegoro/RSUP Dr. Kariadi, Jl. Dr. Sutomo 16-18 Semarang

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : JURNAL GIZI INDONESIA

Hubungan status besi dan ioidum ibu hamil trimester III terhadap berat badan dan lingkar kepala bayi lahir didaerah endemik GAKI Novitasari, Sherly; Hadisaputro, Soeharyo; SS, Darmono; Rachmawati, Banundari; Pemayun, Tjokorda Gde Dalem
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 1 (2016)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.266 KB) | DOI: 10.14710/jgi.5.1.1-6

Abstract

Background: Iodine and iron were micronutrient that highly related with formation of thyroid hormone. Iodine and iron deficiency during pregnancy, will affect fetal development. Weight and born baby’s head circumference were early indicator of infant development, because it describe the result of interaction of several factors for fetus during pregnancy. Objectives: To determine correlation between iodine and iron status of pregnant women in third trimester with born baby’s weight and head circumference. Methods: Cross sectional study with 49 pregnant women on third trimester and their baby born. Measurement of iron status used sTfR level by ELISA and iodine status used EIU. Meanwhile for the born baby, measurement was taken place on the baby’s weight and head circumference. Results: The average of iron status is 22,15 nmol/L, meanwhile average of iodine status is 168,63 μg/L with urine median value 165 μg/L. Statistical analysis with multiple correlation test showed no significant relationship between iron and iodine status of third trimester pregnant women to birth weight (r = 0,286; p = 0,141) as well as the babies head circumference (r = 0,195; p = 0,412).Conclusion: Iron and iodine status of third trimester pregnant women have low correlation to the born babies weight or head circumference in endemic area.
Pengaruh pemberian ekstrak kedelai hitam (Glycine soja.) berbagai dosis terhadap kadar glukosa darah, kadar insulin, dan HOMA-IR Kurniawati, Dewi M; Dharmana, Edi; Rachmawati, Banundari; Pemayun, Tjokorda Gde Dalem
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 6, No 1 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.408 KB) | DOI: 10.14710/jgi.6.1.44-50

Abstract

Background: Obese is risk factor for abnormal glucose homeostasis and causes oxidative stress that can decrease insulin sensitivity resulting in hyperglycemia and hyperinsulinemia. Black soy bean contains anthocyanins and isoflavones, it is expected to reduce oxidative stress. Objective: Determine the effect of various dosage of black soybean extract (Glycine soja.) on blood glucose, insulin levels, and HOMA - IR in obese Sprague Dawley (SD) rats.Methods: True experimental study with randomized controlled pre test-post test design in male SD rats. Twenty four samples divided into 4 groups: control (K), 500 (P1), 750 (P2), and 1000 mg/kgBW (P3). Rats were induced to become obese with High Fat Sucrose Diet (HFSD) for 4 weeks then black soybean extracts were given for 2 weeks..Results: There was no difference in blood glucose before and after treatment (p> 0.05). There were differences on insulin levels in 500 (p = 0.012) and 750mg/kgBW (p = 0.020) doseges. There were differences on HOMA-IR in 500 (p = 0.043) and 750mg/kgBW (p = 0.028) dosages. There was difference in insulin levels’s difference (p = 0.009) between groups.Conclusion: There are differences on insulin levels and HOMA – IR in 500 and 750 mg/kgBW dosages groups. However, there is no difference on blood glucose before and after black soybean extract treatment. The most decreased levels of blood glucose, insulin and HOMA- IR were in 750mg/kgBW dosage.
Hubungan status iodium ibu hamil trimester III dengan status iodium dan nilai antropometri bayi baru lahir di daerah GAKI Pibriyanti, Kartika; SS, Darmono; Pemayun, Tjokorda Gde Dalem
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 2 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (357.208 KB) | DOI: 10.14710/jgi.5.2.75-81

Abstract

Background: Iodine essential for thyroid hormone synthesis. Women in their pregnancy are susceptible of Iodine Deficiency Disorder (IDD) since they are facing metabolism and hormonal alteration. IDD in pregnant women gave bad impact to the growth and development of the fetus. Determinant of the life continuity of the newborn babies and their life qualities could be seen through the newborn baby condition based on their body size proportions right after the birth. Objective : Explaining the impact of the iodine status of the pregnant women in their third trimester to the iodine status and anthropometric values of the newborn babies.Method : This research used non experimental study design cross sectional to 52 pregnant women in their third trimester with the babies. The Urinary Excretion of Iodine (UEI) for the examination of iodine status. To the newborn babies, UEI examination and anthropometric measurement, consists of weight birth (WB), length birth (LB), head circumference (HC) were done. Result : There is a significant correlation between the mothers’ UEI and the LB of the newborn babies (p=0,018). There is no significant correlation between mothers’ UEI and the babies’ UEI (p=1,000), mothers’ UEI and the WB of the newborn babies (p=0,548), mothers’ UEI and the newborn babies’ HC (p=0,885).Conclusion : There is a significant correlation iodine status of the pregnant women in their third trimester <150 µg/L with the LB of the newborn babies <48 cm, but there is no significant correlation with the UEI of the newborn babies <100 µg/L, WB <2500 gram, HC<34 cm.