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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Farmasi Sains dan Komunitas Universa Medicina Medical Laboratory Technology Journal Indonesian Journal of Community Services Medica Arteriana (Med-Art) Journal of Holistics and Health Sciences (JHHS) Jurnal Litbang Edusaintech Jurnal Pengabdian Masyarakat Kedokteran Jurnal Ilmiah Sultan Agung
Danis Pertiwi
Universitas Islam Sultan Agung
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Edukasi dan Pelatihan Pemeriksaan Glukosa Darah di Desa Rembes, Tuntang, Salatiga Pertiwi, Danis; Putri, Andina
Indonesian Journal of Community Services Vol 6, No 2 (2024): November 2024
Publisher : LPPM Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijocs.6.2.209-216

Abstract

Diabetes Melitus (DM) merupakan penyakit metabolik dan salah satu penyakit tidak menular yang dapat menyebabkan komplikasi, baik mikroangiopati maupun makroangiopati di kemudian hari. Diagnosis Penyakit DM ditegakkan melalui pemeriksaan kadar glukosa darah dan HbA1c. Pengendalian glukosa darah yang baik merupakan salah satu faktor penting yang terbukti menurunkan risiko komplikasi pada pasien DM. Tercapainya kendali glukosa yang baik memerlukan penatalaksanaan holistik meliputi edukasi, terapi gizi medik, aktivitas fisik, pemberian obat-obatan dan pemantauan glukosa darah. Pemahaman mengenai DM dan Pemeriksaan Glukosa Darah Mandiri (PGDM) yang benar sangat penting dan dapat disampaikan melalui pendidikan kesehatan. Pendidikan kesehatan seperti penyuluhan dapat meningkatkan kepatuhan dan kualitas hidup pasien.  Masyarakat perlu diberi pengetahuan yang cukup mengenai DM dan PGDM, serta pelatihan PDGM yang benar. Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan masyarakat mengenai DM dan PDGM yang benar. Metode yang digunakan adalah pretest, penyuluhan, pelatihan dan sesi tanya jawab mengenai DM dan PDGM, posttest serta pemeriksaan kadar Glukosa Darah Sewaktu (GDS) kepada Masyarakat Dusun Rembes, Tuntang, Salatiga. Penyuluhan ini terbukti meningkatkan pengetahuan masyarakat, terlihat dari nilai pretest dan posttest peserta mengalami peningkatan yang signifikan (p<0.001). Penyuluhan tentang DM dan PDGM terbukti meningkatkan pengetahuan masyarakat mengenai DM dan PDGM yang benar di masyarakat Desa Rembes Kecamatan Tuntang Kabupaten Salatiga.Diabetes Mellitus (DM) is a metabolic disease and a non-communicable disease that can cause complications, both microangiopathy and macroangiopathy in the future. DM is confirmed by checking blood glucose levels and HbA1c. Good blood glucose control is an important factor proven to reduce the risk of complications in DM patients. Achieving good glucose control requires holistic management including education, medical nutrition therapy, physical activity, medication administration and blood glucose monitoring. Correct understanding of Diabetes Mellitus and Independent Blood Sugar Examination (PGDM) is very important and can be conveyed through health education. Health education such as counseling can improve patient compliance and quality of life. The public needs to be given sufficient knowledge about DM and Independent Blood Sugar Examination, as well as training in correct independent blood sugar checks. The aim of this activity is to increase public knowledge regarding Diabetes Mellitus and correct independent blood sugar checks. The methods used were pretest, counseling, training and question and answer sessions regarding Diabetes Mellitus and Independent Blood Sugar Examination, posttest as well as checking Temporary Blood Sugar for the people of Rembes Hamlet, Tuntang, Salatiga. This counseling was proven to increase public knowledge, as seen from the participants' pretest and posttest scores which experienced a significant increase (p<0.0001). Counseling about Diabetes Mellitus and Independent Blood Sugar Checks has been proven to increase public knowledge about Diabetes Mellitus and correct Independent Blood Sugar Examination in Village Communities Assisted by FK Unissula.
Effect of Astaxanthin Cream on MMP-1 and SOD Expression in Wistar Rats Exposed to ultraviolet B Rachmawati, Nita; Pertiwi, Danis; Thomas, Siti
Medical Laboratory Technology Journal Vol. 11 No. 1 (2025): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i1.632

Abstract

Ultraviolet B (UVB) exposure is the main cause of skin damage leading to photoaging, increasing Reactive Oxygen Species (ROS) and triggering the production of Matrix metalloproteinase-1 (MMP-1) enzymes that play an important role in photoaging, describing clinical signs including wrinkles, thickening, dryness and pigmentation. Astaxanthin can inhibit ageing and reduce wrinkles, has strong antioxidant potential that can neutralize ROS, and suppress MMP-1 activity. The purpose of this study was to determine the effect of astaxanthin cream on the levels of MMP-1 and Superoxide Dismutase (SOD) enzyme production in mouse skin tissue exposed to short-term UVB light experimental research with a post-test-only control group design. The experimental animals used were 28 Wistar rats divided into 4 groups, namely group K1 (healthy), group KN exposed to short-term UVB and given base cream, group P1 exposed to short-term UVB rays and given 0.05% astaxanthin cream, and group P2 exposed to short-term UVB rays and given 0.1% astaxanthin cream. The treatment was carried out for 5 days, and on the 6th day, the levels of MMP-1 enzyme production in skin tissue and SOD were examined using the immunohistochemical method. Based on One-way ANOVA, there was a significant difference in the average levels of MMP-1 enzyme production in the skin tissue of all groups (p = 0.000). The highest MMP-1 production was found in the KN group, while in the P2 group, the levels were lower and not significantly different from the healthy group (K1). Significant differences in SOD expression were also observed among all groups (p = 0.000) using the Kruskal-Wallis test. The highest SOD expression was found in group P2 and was significantly different from groups P1 and KN. Topical astaxanthin cream administration affected MMP-1 enzyme production in skin tissue and SOD expression in Wistar rats exposed to short-term UVB radiation. Astaxanthin-based cream formulation has the potential to be developed as a topical agent to prevent skin damage caused by sun exposure, and these findings require further validation through studies on human skin models or early clinical trials.
Edukasi Peran Vitamin D dalam Kesehatan di Puskesmas Halmahera, Puskesmas Pandanaran, dan Rumah Sakit Islam Sultan Agung Pertiwi, Danis; Sampurna, Sampurna; Aulia, Andina Putri; Puspaningrum, Dimar Kumala; Azari, Rahmadani Ayu
Indonesian Journal of Community Services Vol 7, No 2 (2025): November 2025
Publisher : LPPM Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijocs.7.2.229-237

Abstract

Vitamin D merupakan vitamin larut lemak yang memiliki peran krusial dalam mengatur metabolisme kalsium dan fosfor, serta mendukung fungsi sistem imun dan pencegahan berbagai penyakit. Meski Indonesia kaya akan paparan sinar matahari, defisiensi vitamin D tetap menjadi masalah, terutama pada kelompok rentan seperti wanita lansia dan pekerja dalam ruangan. Kekurangan vitamin D dapat menyebabkan berbagai masalah kesehatan, seperti osteoporosis, preeklamsia pada kehamilan, dan melemahnya sistem imun. Penyuluhan mengenai vitamin D menjadi langkah penting untuk meningkatkan pemahaman masyarakat tentang fungsi, manfaat, dan sumber vitamin D. Kegiatan ini bertujuan meningkatkan pengetahuan masyarakat dengan metode pretest, penyuluhan, pelatihan, sesi tanya jawab, posttest, serta pemeriksaan kadar vitamin D pada peserta dari Puskesmas Pandanaran, Puskesmas Halmahera, dan Rumah Sakit Islam Sultan Agung. Hasilnya menunjukkan bahwa penyuluhan ini secara signifikan meningkatkan pemahaman peserta, terbukti dari peningkatan nilai pretest dan posttest (p<0.001). Dengan demikian, edukasi tentang vitamin D terbukti efektif dalam meningkatkan kesadaran peserta di ketiga lokasi tersebut.Vitamin D is a fat-soluble vitamin that plays a crucial role in regulating calcium and phosphorus metabolism, supporting immune system function, and preventing various diseases. Despite Indonesia’s abundant sunlight exposure, vitamin D deficiency remains a significant issue, particularly among vulnerable groups such as elderly women and indoor workers. A lack of vitamin D can lead to various health problems, including osteoporosis, preeclampsia during pregnancy, and weakened immune function. Public education on vitamin D is an essential step in raising awareness about its functions, benefits, and dietary sources. This program aimed to enhance public knowledge using methods such as pretests, health education sessions, training, interactive Q&A, posttests, and vitamin D level assessments among participants from Puskesmas Pandanaran, Puskesmas Halmahera, and Sultan Agung Islamic Hospital. The results indicated that the education sessions significantly improved participants’ understanding, as reflected in the increase in pretest and posttest scores (p<0.001). Thus, education about vitamin D has proven effective in raising awareness among participants at the three locations.
Co-Authors Ady Try Himawan Zen, Ady Try Himawan Ari Natalia Probandari Athatsaniya, Mazaya Denta Atina Hussaana Aulia, Andina Putri Azari, Rahmadani Ayu Bagas Widiyanto, Bagas Chodidjah Chodidjah Guscella, Dede Hadi Sarosa Joko Wahyu Wibowo Joko Wahyu Widodo Maritsatun Nisa&#039; Minidian Fasitasari Muchlis Achsan Udji Sofro Nenik Faozah Puspaningrum, Dimar Kumala Putri, Andina Rachma Purnama Sari Rachmawati, Nita Rahayu Rahayu Riza, Mohamad Sampurna Sampurna Sampurna Sampurna, Sampurna Taufiqurrachman Nasihun Thomas, Siti Titiek Sumarawati Tri Indah Winarni Ulfah Dian Indrayani