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All Journal International Journal of Public Health Science (IJPHS) Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Ilmu Kesehatan Masyarakat JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal SOLMA Jurnal Farmasi Sains dan Praktis
Dian Prasasti
Fakultas Farmasi UAD
Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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STUDI KAPASITAS ADSORPSI-REDUKSI ION Au(III) PADA ASAM HUMAT HASIL ISOLASI DARI TANAH GAMBUT RAWA PENING Prasasti, Dian; Juari, Sri; Sudiono, Sri
PHARMACIANA Vol 2, No 2: November 2012
Publisher : PHARMACIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.03 KB)

Abstract

Isolasi asam humat dan aplikasinya untuk adsorpsi-reduksi ion Au(III) telah dilakukan. Asam humat diisolasi dari tanah gambut yang diambil dari Rawa Pening, Jawa Tengah. Isolasi asam humat dari tanah gambut didasarkan pada metode ekstraksi tradisional basa. Isolasi asam humat dilakukan dengan mengekstraksi asam humat dari tanah gambut dengan 0,1 M NaOH dan mengendapkan dengan 0,1 M HCl kemudian dilakukan pencucian dengan 0,1 M HCl/0,3 M HF 1/1. Asam humat dikarakterisasi dengan spektroskopi Fourier-Transform Infrared (FTIR) kemudian diaplikasikan untuk adsorpsi-reduksi ion Au(III). Kapasitas adsorpsi menggunakan model isoterm adsorpsi terhadap proses adsorpsi reduksi ion Au(III) juga telah dipelajari. Logam Au yang terbentuk dikonfirmasi dengan difraktogram XRD dan foto mikroskop optik. Hasil perhitungan kapasitas adsorpsi dengan model isotherm Langmuir asam humat adalah 192 mg/g. Pembentukan logam Au ditunjukkan oleh munculnya puncak pada 2_ = 38, 44, dan 64 dalam difraktogram XRD.
RELATIONSHIP BETWEEN HANDWASHING HABITS WITH DIARHEA INCIDENT IN CHILDREN UNDER TWO YEARS Arini, Shintia Yunita; Pramesti, Nala Astari; Prasasti, Dian; Awwalina, Isas
Jurnal Ilmu Kesehatan Masyarakat Vol 17 No 1 (2021)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ikesma.v17i1.22420

Abstract

Diarrhea in children under five based on diagnosis and symptom occurred in 18.5% of children in 2018 and 12.3% of children in 2013, indicating an increase. According to the health profile of Bojonegoro Regency of 2018, out of 33,667 diarrhea cases reported, 31,010 or 92.11% of them were treated. This study aims to analyze the relationship between handwashing practice, use of latrine and SPAL (sewerage) with diarrhea incidents in Bojonegoro Incidents. This study used observational study design with cross-sectional approach. Samples in this study were 63 toddlers spread across 4 villages taken using proportional random sampling technique. The collection of primary data was performed by interviewing and observing mothers that had toddlers. Chi square test method was used to determine the relationship between variables examined, where diarrhea occurred in children under five if p < α (α margin of error = 0.05). The results of the study conducted from December 27, 2019 to January 31, 2020 showed that there was a significant relationship between handwashing habit and diarrhea incidents in toddlers, with p=0.000. There was no significant relationship between latrine condition and diarrhea in toddlers, with p=0.808. Furthermore, there was no significant relationship between SPAL condition and diarrhea incidents in toddlers, with p=0.085. There was a significant relationship between handwashing habits in mothers that had children under two with diarrhea incidents.
Groundwater and indoor air quality of urban village housing: study in Janturan, Warungboto, Yogyakarta Mahfudh, Nurkhasanah; Prasasti, Dian; Ananda, Anugrah Tri; Rahmawati, Frida; Sulistyawati, Sulistyawati; Muchlis, Muchlis; Murtyas, Solli Dwi; Hagishima, Aya
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.23865

Abstract

Water and air are important elements for life. The presence of pathogenic bacteria in the surrounding environment can cause health problems resulting from the low quality of water and air. The purpose of this study is to measure the quality of groundwater and air based on microbiological parameters in urban village housing. This research was conducted in a descriptive survey, and a purposive sampling technique was carried out. Groundwater and air samples were taken from six residents' houses located in the Janturan area. The water quality test used the most probable number (MPN) method and the air quality test used the agar filter method using a microbiological air sampler (MAS) to trap microbes. The results of the MPN test for total coliform bacteria from six samples of groundwater showed that three samples were positive for coliform bacteria which exceeded the threshold according to Indonesian standard<50 MPN/100 ml. Assay of E. coli bacteria showed that all samples of groundwater positively contained E. coli bacteria which exceeded the threshold of 0 MPN/100 ml. The results of indoor air quality measurements from 6 residents' houses showed that five houses have air quality did not meet the standard for indoor air germ numbers based on Indonesian standard, less than 700 CFU/m3 (colony forming units per metres cubic) and 1 house that got the number of airborne germs, in the normal range, namely 356 CFU/m3. It was concluded that the water quality and air quality in the urban village did not meet health requirements.
AUTHENTICATION OF PATCHOULI OIL FROM VARIOUS GROWING REGIONS USING GC-MS METHOD WITH CHEMOMETRIC COMBINATION ON THE PRODUCTS IN THE MARKET Nurani, Laela Hayu; Guntarti, Any; Milanie, Rida Dwi; Gandjar, Ibnu Gholib; Rais, Ichwan Ridwan; Prasasti, Dian; Edityaningrum, Citra Ariani
Jurnal Farmasi Sains dan Praktis Vol 10 No 1 (January-April 2024)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v10i1.10523

Abstract

Adulteration in patchouli oil trade is an ancient practice, where additional substances like turpentine oil are added to increase volume and odor. Therefore, this research aimed to determine the composition of patchouli oil, considering variations in growing regions and potential adulteration in the products available in the market. The analysis was carried out using the Gas Chromatography-Mass Spectrormetry (GC-MS) method with a Principal Component Analysis (PCA) chemometric combination for authentication. The sample obtained from Bantul, Kulon Progo, and Purworejo was isolated through steam and water distillation. Subsequently, it was tested in accordance with SNI standard 06-2385-2006 and analyzed using GC-MS. The results were compared to the products on the market and processed using multivariate chemometric, namely PCA with Minitab 19 software. GC-MS analysis showed the presence of various compounds contained in the oil, including alcohol, alpha-guaiene, beta-humulene, seychellene, trans-caryophyllene, neoalloocimene, and beta-patchoulene. The combination of GC-MS and PCA chemometrics was able to distinguish patchouli oil from others and the products available on the market. PCA chemometric analysis showed that the patchouli oil from various growing regions had the same chemical components as essential oil. Furthermore, PCA chemometric analysis of market products also showed similar results but varied significantly from turpentine oil. This showed that the patchouli oil product available on the market did not contain turpentine oil.
Antihypertensive Activity of Black Garlic Extract in Rats and Its Phytochemical Analysis using GC-MS Estiningsih, Daru; Saiful Bachri, Moch; Hayu Nurani, Laela; Ma’ruf, Muhammad; Yuliani, Sapto; Sofia, Vivi; Prasasti, Dian
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 1 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i12025.67-74

Abstract

Background: Hypertension is defined as a medical condition where blood pressure rises above 140/90 mmHg. Black garlic is recognized as a natural remedy that may help lower high blood pressure, primarily due to its abundant antioxidant properties, which are believed to inhibit the function of the angiotensin-converting enzyme (ACE) that is essential for regulating blood pressure. Objective: This study aimed to identify the chemical composition of black garlic using GC-MS and assess its antihypertensive effects in rat models. Methods: This study characterized the chemical composition of black garlic using GC-MS (Agilent 7890A) and evaluated its antihypertensive effects in rats. Hypertension was induced by oral administration of NaCl at a dose of 3.75 g/20 g body weight (BW) from day 0 to day 14. Blood pressure measurements were taken on days 0, 14, and 21. Black garlic extract was administered at three dose levels 4.2 mg/20 g BW, 8.4 mg/20 g BW, and 12.4 mg/20 g BW to evaluate dose dependent antihypertensive responses. Statistical analysis included the Kolmogorov-Smirnov test for normality, homogeneity testing, One-Way ANOVA Results: The GC-MS analysis identified 9-octadecenoic acid as the dominant compound in black garlic, accounting for 34.53% of its total composition. The antihypertensive activity test showed that administering black garlic at a dose of 12.4 mg/20 g BW significantly lowered systolic, diastolic, and mean arterial blood pressure while enhancing nitric oxide levels in hypertensive rats. Conclusion: Black garlic has the potential as an effective herbal treatment to lower blood pressure.
IDENTIFIKASI RESIDU PESTISIDA ORGANOFOSFAT PADA BAWANG MERAH DI KABUPATEN KULON PROGO Prasasti, Dian; Perwitasari, Dyah Aryani
Media Farmasi: Jurnal Ilmu Farmasi Vol 14, No 2 : September 2017
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v14i2.11236

Abstract

Di Indonesia pestisida organofosfat banyak digunakan pada tanaman buah dan sayuran seperti bawang merah. Pestisida organofosfat mengalami translokasi ke seluruh bagian tanaman sehingga residu pestisida organofosfat dapat tertinggal di umbi bawang merah yang dikonsumsi oleh masyarakat. Di Kabupaten Kulon Progo Provinsi DIY, pestisida organofosfat banyak digunakan terutama oleh petani bawang merah. Metode penelitian menggunakan rancangan observasional dan experimental. Sampel bawang merah diambil dari 10 petani yang tersebar di Kabupaten Kulonprogo. Kuisioner dibagikan kepada petani mengenai jenis pestisida yang digunakan dan waktu diaplikasikan oleh petani serta frekuensi penggunaan pestisida. Penentuan kadar organofosfat dilakukan dengan melakukan proses ekstraksi bawang merah dengan aseton, diklorometan, dan petroleum benzena kemudian dianalisis menggunakan kromatografi gas. Pestisida organofosfat yang diuji residunya adalah diazinon, parathion, ethion, profenofos, malation, dan klorpirifos. Hasil dari kuisioner kepada petani bawang merah, pestisida organofosfat yang digunakan adalah pestisida dengan bahan aktif profenofos dan klorpirifos dengan rata-rata penggunaan 0,5% (v/v) sekali penyemprotan. Hasil analisis residu pestisida organofosfat menunjukkan bahwa sampel bawang merah dari 1 petani mengandung diazinon dengan kadar rata-rata 1,97 ppb. Residu pestisida pada bawang merah dari 9 petani menunjukkan hasil tidak terdeteksi untuk pestisida diazinon, parathion, ethion, profenofos, malation dan klorpirifos. Batas deteksi  (LOD) untuk metode analisis pestisida organofosfat yang digunakan adalah diazinon 3,7 ppb, parathion 6,4 ppb, ethion 4,3 ppb, profenofos 4,8 ppb, malathion 1,24 ppb, dan klorpirifos 0,83 ppb.
Analisis Hidrokuinon Pada Bleaching Cream Yang Dijual Secara Online Dan Tidak Memiliki Izin Edar Dari Bpom Lestari, Windy Rizky; Prasasti, Dian
Media Farmasi: Jurnal Ilmu Farmasi Vol. 15 No. 1: Maret 2018
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v15i1.12357

Abstract

Penggunaan produk pemutih kulit di Indonesia terus meningkat dari tahun ke tahun. Salah satu jenis  produk pemutih kulit adalah bleaching cream. Saat ini banyak ditemukan produk bleaching cream ilegal yang dijual secara online. Badan Pengawasan Obat dan Makanan menemukan 868 jenis kosmetik ilegal mengandung bahan berbahaya seperti hidrokuinon. Hidrokuinon adalah bahan yang digunakan untuk memutihkan kulit dengan cara menghambat aktivitas enzim tirosinase. Penggunaan hidrokuinon pada kosmetik di Indonesia tidak diperbolehkan karena dapat mengakibatkan masalah pada kulit dan menyebabkan kanker. Penelitian ini bertujuan untuk mengetahui adanya kandungan dan kadar hidrokuinon pada bleaching cream yang dijual secara online dan tidak memiliki izin BPOM. Lima sampel bleaching cream yang dibeli secara online diuji secara kualitatif dan uji kuantitatif. Uji kualitatif  dengan menggunakan pereaksi warna FeCl3. Uji kuantitatif  menggunakan HPLC, fase gerak yang digunakan yaitu metanol : aquadest (55:45) dan fase diam yang digunakan adalah ODS/C-18. Terdapat kandungan hidrokuinon pada 5 sampel bleaching cream yang dijual secara online dan tidak memiliki izin BPOM dari 5 sampel bleaching yang dianalisis. Kadar hidrokuinon pada sampel bleaching cream pada sampel A 8,76, sampel B 6, 96 , sampel C 4,07 , sampel D 0,12 , dan sampel E 0,07 . Hasil uji statistika menggunakan Uji Brown Forsythe dan Uji Welch diperoleh nilai signifikansi (Sig) sebesar 0,000 dimana nilai tersebut kurang dari 0,005 yang berarti terdapat perbedaan bermakna kadar hidrokuinon pada setiap sampel bleaching cream yang dianalisis.
Pemberdayaan Perempuan melalui Program Womenpreneur: Meningkatkan Akses dan Keterampilan Bisnis Christian, Adhitya Rechandy; Prasasti, Dian; Sukardi, Sukardi
Jurnal SOLMA Vol. 14 No. 3 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i3.20931

Abstract

Background: Warung-Mu berlokasi strategis di area Masjid Miniatur Baiturrahman Aceh, Warung-Mu menghadapi tantangan khas UMKM berupa rendahnya kapasitas manajerial, pencatatan keuangan yang belum profesional, minimnya literasi pemasaran digital, dan terbatasnya anggaran promosi. Kegiatan Pengabdian kepada Masyarakat (PkM) ini bertujuan meningkatkan keberdayaan mitra melalui peningkatan kapasitas manajemen usaha dan pemasaran digital pada Warung-Mu, sebuah UMKM kuliner yang dikelola ibu-ibu Ranting Aisyiyah di Tirtonirmolo, Bantul, Yogyakarta. Metode: Metode pelaksanaan meliputi lima tahap: (1) analisis kebutuhan dan perencanaan, (2) peningkatan kapasitas manajemen usaha, (3) pelatihan pemasaran digital dan pembuatan konten kreatif, (4) pengembangan usaha dan branding melalui media sosial, website, dan integrasi marketplace, serta (5) monitoring dan evaluasi keberlanjutan. Hasil: Hasil kegiatan menunjukkan peningkatan signifikan dalam literasi manajemen, kemampuan pencatatan keuangan, dan pemahaman pemasaran digital. Pengurus Warung-Mu berhasil membuat konten promosi melalui Instagram, Facebook, TikTok, serta website resmi, dan memanfaatkan direct marketing dengan pembagian voucher untuk meningkatkan jangkauan pasar. Selain itu, penentuan Harga Pokok Produksi (HPP) dan pelatihan segmenting-targeting-positioning (STP) memperkuat strategi produk. Inovasi fisik berupa pemasangan neon box dan integrasi ke platform Gojek serta Shopee Food memperluas akses pelanggan. PkM ini membuktikan bahwa pendampingan berbasis kekuatan lokal, literasi digital, dan pengelolaan usaha yang profesional dapat meningkatkan daya saing dan keberlanjutan UMKM di era ekonomi digital. Kesimpulan: Kegiatan PkM berhasil menjawab dua permasalahan utama, yaitu keterbatasan kapasitas manajemen usaha dan rendahnya kemampuan manajemen pemasaran.
Co-Authors Ananda, Anugrah Tri Any Guntarti Awwalina, Isas Christian, Adhitya Rechandy Citra Ariani Edityaningrum, Citra Daru Estiningsih Dyah Aryani Perwitasari Hagishima, Aya Ibnu Gholib Gandjar Ichwan Ridwan Rais Laela Hayu Nurani Lestari, Windy Rizky Milanie, Rida Dwi Moch. Saiful Bachri Muchlis Muchlis Muhammad Ma'ruf Murtyas, Solli Dwi Nurkhasanah Mahfudh Pramesti, Nala Astari Rahmawati, Frida Sapto Yuliani Shintia Yunita Arini, Shintia Yunita Sri Juari Sri Sudiono Sukardi Sukardi Sulistyawati Sulistyawati Vivi Sofia