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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Skala Kesehatan JOURNAL SCIENTIFIC OF MANDALIKA (JSM) Jurnal Insan Farmasi Indonesia Jurnal Bakti Untuk Negeri JHESS: Journal Hub for Humanities and Social Science
Muhammad Ma'ruf
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Madu lebah kelulut (Trigona Spp.) dalam aktifitas terhadap bakteri Staphylococcus aureus resisten Muhammad Ma'ruf; Gina Alia Mawaddah; Nisa Nur Agistni Eriana; Farah Indah Swari; Syaidatul Aslamiyah; Leka Lutpiatina
Jurnal Skala Kesehatan Vol 9 No 1 (2018): JURNAL SKALA KESEHATAN
Publisher : Politeknik Kementerian Kesehatan Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (532.153 KB) | DOI: 10.31964/jsk.v9i1.151

Abstract

Infection caused by Staphylococcus aureus bacteria becomes a very serious problem because of the increased resistance of these bacteria to various types of antibiotics. Honey has antibacterial activity because it contains water, acidity and inhibitor compounds namely flavonoids. Honey can be produced Trigona spp. This study aims to Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) and effectiveness of honey bee kelulut (Trigona spp.) Against Staphylococcus aureus resistant cephalosporin bacteria in vitro. This research is true experiment with postest only control group design. The results of the study were measured by MIC showed no clarity at concentrations of 60 mg / ml, 70 mg / ml, 80 mg / ml, 90 mg / ml and and clarity at concentrations of 100 mg / ml, and MBC at concentrations of 60 mg / ml of 151 colonies, 70 mg / ml of 105 colonies, 80 mg / ml of 55 colonies, 90 mg / ml of 16 colonies and 100 mg / ml of 0 colonies. The effective concentration in killing Staphylococcus aureus resistant cephalosporin is 100 mg / ml
PEMERIKSAAN KESEHATAN GRATIS KEPADA MASYARAKAT DESA TATAH LAYAP, KECAMATAN TATAH MAKMUR, KABUPATEN BANJAR Muhammad Ma'ruf; shafran ilahi, fitrah; Prihandiwati, Erna; Susanto, Yugo; Ariani, Novia; Musiam, Siska; Wahyuni, Amaliyah; Rizki Febrianti, Dwi; Puteri Amalia, Senya; Ayu Lestari, Desy
Jurnal Bakti untuk Negeri Vol 5 No 1 (2025): Jurnal Bakti Untuk Negeri
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/f556kt16

Abstract

Regular health check-ups play a vital role in detecting health disorders early to prevent and treat illnesses appropriately. The free health check-up program in Tatah Layap Village, Tatah Makmur Subdistrict, Banjar Regency, aims to raise community awareness about the importance of promotive and preventive measures in maintaining health. This activity includes health education through communication, information, and education (CIE) approaches, as well as direct health examinations for the community. The program was attended by 85 participants who gained valuable information and understanding of the importance of regular health check-ups. The examination results served as a guide for participants to monitor and maintain their health conditions. This program is expected to enhance community awareness about the significance of routine health check-ups as a preventive measure to reduce the risk of future illnesses
Total Plate Count Minuman Sari Buah yang Dijual Pedagang Kaki Lima di Kecamatan Semarang Barat Anisa Nova Puspitaningrum; Valentina Girsang; Muhammad Ma'ruf; Fransisca Gloria; Madyo Adrianto; Cecep Sabarudin
Journal Scientific of Mandalika (JSM) e-ISSN 2745-5955 | p-ISSN 2809-0543 Vol. 6 No. 4 (2025)
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/10.36312/vol6iss4pp983-987

Abstract

Microbial contamination can cause health issues that are disruptive, harmful, and potentially dangerous to health. Microbial contamination is often found in beverages widely sold on the streets, where water quality and cleanliness are often neglected. This study aims to determine the level of microbial contamination in fruit juice products sold in Semarang. The five samples used were lemon, mango, avocado, orange, and tomato juices, which were tested using the Total Plate Count method. The results of this study showed that the Total Plate Count (TPC) values of three samples such as lemon, mango, and avocado juices, did not meet the requirements of SNI 01-3719-1995. Meanwhile, two samples, orange and tomato juices, were concluded to still comply with the threshold set by SNI 01-3719-1995.
Jejak Pembaruan dalam Studi Al Qur'an: Analisis atas Metode Tafsir Muhammad Arkoun Ghina Adilah; Muhammad Ma'ruf; Siddik Hasonangan Simamora
Journal Hub for Humanities and Social Science Vol. 2 No. 2 (2025): 2025: July - December
Publisher : Yayasan Masjid Al-Muhajirin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63847/nxc5hc06

Abstract

Muhammad Arkoun adalah salah satu tokoh pemikir Islam kontemporer yang berperan penting dalam merumuskan metode penafsiran Al-Qur’an. Ia memperkenalkan pendekatan yang kritis dan inovatif dengan mengintegrasikan beragam disiplin ilmu modern seperti linguistik, antropologi, dan sejarah dalam proses penafsiran. Arkoun menolak pembacaan literal dan tekstual yang sempit, serta menekankan pentingnya memahami Al-Qur’an sebagai wacana yang berkembang dalam ruang sosial dan historis tertentu. Pendekatan ini memberikan arah baru dalam penafsiran Al-Qur’an yang lebih kontekstual dan relevan terhadap dinamika zaman modern. Kontribusi Arkoun menjadi titik tolak peralihan dari metode tafsir tradisional seperti tafsir bil ma’tsur menuju model interdisipliner yang lebih terbuka dan inklusif. Pemikirannya membuka cakrawala baru dalam studi tafsir, yang bersifat kritis dan dialogis lintas disiplin. Ia juga mendorong lahirnya penafsiran Al-Qur’an yang tidak hanya bersifat normatif, tetapi juga analitis dan reflektif terhadap kondisi sosial. Artikel ini bertujuan untuk menganalisis metode tafsir yang ditawarkan Arkoun serta signifikansinya dalam perkembangan studi tafsir kontemporer.
Analysis of bioactive compounds, antioxidant activity, and acute toxicity test of black garlic (Allium sativum L.) Moch. Saiful Bachri; Muhammad Ma'ruf; Hasna Tsamarah; Daru Estiningsih; Prasasti, Dian; Danang Prasetyaning Amukti; Sapto Yuliani; Vivi Sofia
Pharmaciana Vol. 15 No. 3 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i3.31393

Abstract

Black garlic is obtained through a controlled fermentation process that alters its color, aroma, and flavor while enhancing its concentration of bioactive compounds. This product is rich in phenolics, flavonoids, alkaloids, and organosulfur compounds such as S-allyl cysteine, which are known to exhibit antioxidant, anti-inflammatory, and antimicrobial properties. This study aimed to determine the total alkaloid, flavonoid, and phenolic content, antioxidant activity, and acute toxicity profile of black garlic. Black garlic samples were prepared by fermenting Solo garlic for 12 days at 60–70 °C. Alkaloid content was analyzed spectrophotometrically using Bromocresol Green reagent with quinine as the standard, flavonoid content was determined using quercetin, and total phenolic content was measured using the Folin–Ciocalteu method with gallic acid as the standard. Antioxidant activity was assessed using the DPPH method, while acute toxicity testing was conducted on male BALB/c mice at doses of 500–5.000 mg/kg BW following OECD/GHS guidelines. The results showed that black garlic contained 301.65 ± 3.436 mg QE/kg alkaloids, 2.190 ± 0.051 mg QE/g flavonoids, and 81.976 ± 1.179 mg GAE/g phenolics. Antioxidant activity was categorized as very strong with an IC₅₀ value of 9.94 ± 0.012 ppm, comparable to Vitamin C (9.92 ± 0.005 ppm). Acute toxicity tests revealed no toxic symptoms or mortality up to 5.000 mg/kg BW, classifying black garlic as practically non-toxic. In conclusion, black garlic is rich in bioactive compounds, demonstrates strong antioxidant activity, and is safe for consumption, making it a potential functional food and health supplement.
STANDARISASI EKSTRAK ETANOL BAWANG DAYAK (Eleutherine bulbosa (Mill.) Urb) MELALUI ANALISIS PARAMETER SPESIFIK DAN NON-SPESIFIK Shafala Rivani Aisyah; Moch. Saiful Bachri; Laela Hayu Nurani; Sapto Yuliani; Silmi Kaffah; Sri Rahmawati; Muhammad Ma'ruf; Danang Prasetyaning Amukti
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/276ecv08

Abstract

Latar belakang: Bawang dayak (Eleutherine bulbosa (Mill.) Urb) merupakan bahan alami yang diolah menjadi ekstrak etanol dari umbi tanaman, dan sangat memerlukan proses standardisasi guna menjamin kualitas, keamanan, serta efektivitasnya secara konsisten bagi konsumen. Penelitian ini bertujuan untuk menilai mutu ekstrak etanol bawang dayak yang diperoleh dari wilayah Sintang, Kalimantan Barat melalui pengujian terhadap parameter spesifik dan nonspesifik. Metode: Pengujian dilakukan dengan mengukur parameter non spesifik dan parameter spesifik. Hasil: Uji laboratorium dilakukan dengan mengukur kadar air (6,31%), abu total (2,27%), dan sari larut etanol (10,84%) sebagai indikator nonspesifik yang merefleksikan stabilitas dan tingkat kemurnian bahan. Sementara itu, parameter spesifik menunjukkan kandungan flavonoid total sebesar 8,416 mgQE/g dan fenolik total sebesar 75,026 mgGAE/g, yang mengindikasikan potensi tinggi terhadap aktivitas antioksidan dan manfaat farmakologis. Kesimpulan: Berdasarkan hasil tersebut, ekstrak etanol bawang dayak dinilai telah memenuhi standar mutu dan berpotensi untuk dikembangkan sebagai bahan baku obat herbal, meskipun kajian lanjutan tetap diperlukan guna mengoptimalkan penerapannya dalam formulasi farmasi yang lebih luas.
PROFIL KANDUNGAN FENOLIK DAN EVALUASI PARAMETER NON-SPESIFIK EKSTRAK ETANOL RIMPANG JAHE MERAH (Zingiber officinale var. rubrum) Sundari, Trias Kania; Bachri, Moch. Saiful; Laela Hayu Nurani; Wahyu Widyaningsih; Muhammad Ma'ruf
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/wpv2vp92

Abstract

Jahe merah (Zingiber officinale var. rubrum) merupakan tanaman obat yang diketahui memiliki aktivitas antiinflamasi dan antioksidan. Penelitian ini bertujuan untuk menstandarisasi ekstrak etanol jahe merah melalui penentuan kandungan fenolik total dan parameter non-spesifik. Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 75% selama 1x24 jam. Kandungan fenolik total dianalisis dengan menggunakan metode Follin-Ciocalteu dan hasilnya dinyatakan dalam satuan mg GAE. Parameter non-spesifik yang ditentukan meliputi kadar air, kadar abu, dan kadar sari larut etanol dengan metode gravimetri. Hasil analisis menunjukkan ekstrak etanol jahe merah memiliki kadar air sebesar 12,87%, kadar abu 7,45%, kadar sari larut etanol 6,23% dan kandungan fenolik total sebesar 136,7mg GAE/g ekstrak. Data ini memberikan dasar ilmiah untuk standarisasi ekstrak jahe merah sehingga dapat digunakan sebagai bahan baku produk farmasi dengan mutu yang terukur.
Co-Authors Anisa Nova Puspitaningrum Ariani, Novia Ayu Lestari, Desy Cecep Sabarudin Danang Prasetyaning Amukti Daru Estiningsih Dian Prasasti Farah Indah Swari Fransisca Gloria Ghina Adilah Gina Alia Mawaddah Hasna Tsamarah Laela Hayu Nurani leka lutpiatina, leka Madyo Adrianto Moch. Saiful Bachri Moch. Saiful Bachri Nisa Nur Agistni Eriana Prihandiwati, Erna Puteri Amalia, Senya Rizki Febrianti, Dwi Sapto Yuliani Shafala Rivani Aisyah shafran ilahi, fitrah Siddik Hasonangan Simamora Silmi Kaffah Siska Musiam Sri Rahmawati Sundari, Trias Kania Susanto, Yugo Syaidatul Aslamiyah Valentina Girsang Vivi Sofia Wahyu Widyaningsih Wahyuni, Amaliyah