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All Journal Damianus Journal of Medicine Journal of Health (JoH) GANEC SWARA Jurnal Inovasi Teknik Kimia Jurnal Mandala Pengabdian Masyarakat Buletin Poltanesa Nutriology: Jurnal Pangan, Gizi, Kesehatan Jurnal Ilmiah Kesehatan (JIKA) Karya Kesehatan Siwalima
Lina Yunita
Department Of Nutrition, Faculty Of Health, Universitas Bumigora, Mataram
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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PTEN: The Potential Therapeutic Target of Diabetes Mellitus Ni Made Wiasty Sukanty; I Putu Bayu Agus Saputra; Lina Yunita
Poltanesa Vol 24 No 1 (2023): June 2023
Publisher : P2M Politeknik Pertanian Negeri Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51967/tanesa.v24i1.2004

Abstract

Diabetes mellitus is a metabolic disease characterized by high blood glucose levels. The cause of glucose control failure is decreased insulin production by pancreatic β-cells and insulin resistance. Both lead to the obstacle of glucose uptake into cells. The mechanism of glucose uptake into cells is crucial in carbohydrate metabolism. This mechanism aims to produce energy in the form of ATP. The main signaling pathway after the process of glucose uptake is the PI3K/Akt pathway. This pathway involves many proteins activated by phosphorylation mechanisms. One of the proteins involved in this pathway is PTEN, a PI3K regulator. PTEN activity can dephosphorylate PI3K so that the insulin signaling pathway becomes blocked and glucose cannot be uptaken into cells. It causes blood glucose levels to increase. The role of PTEN in inhibiting the PI3K/Akt pathway seems to be a crucial matter to observe. By inhibiting PTEN activity, the insulin signaling pathway is expected to work properly. We have searched, read, analyzed, and summarized various studies regarding the potential of PTEN to reduce diabetes mellitus cases. In some research articles, the use of active compounds and therapy using stem cells to inhibit PTEN activity has shown good progress in the insulin signaling pathway. Based on these, it can be an option to make PTEN a target for diabetes mellitus therapy.
Edukasi Label Informasi Nilai Gizi Sebagai Upaya Peningkatan Pengetahuan dan Kemampuan Membaca Label Gizi Siswa di SMAN 5 Mataram: Education on Nutritional Value Information Labels as an Effort to Increase Knowledge and Ability to Read Nutrition Labels for Students at SMAN 5 Mataram Novianti Tysmala Dewi; Lina Yunita; Ni Made Wiasty Sukanty; Farida Ariani
Jurnal Mandala Pengabdian Masyarakat Vol. 4 No. 1 (2023): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v4i1.225

Abstract

Label informasi nilai gizi adalah label kemasan yang memuat daftar kandungan gizi makanan dan komponen lainnya seperti takaran saji, jumlah takaran saji, dan persen angka kecukupan gizi. Data Badan Perlindungan Konsumen Nasional (BPKN) menunjukkan bahwa hanya 7,9% konsumen yang memperhatikan dan membaca label informasi nilai gizi. Kurangnya pengetahuan tentang label informasi nilai gizi dapat memengaruhi pola konsumsi, menyebabkan kegemukan, dan obesitas. Remaja tergolong salah satu konsumen yang paling aktif dalam mengonsumsi makanan kemasan. Salah satu cara untuk meningkatkan pengetahuan remaja tentang informasi nilai gizi adalah dengan memberikan edukasi. Selain bertujuan untuk meningkatkan pengetahuan dan kemampuan siswa, edukasi terkait label gizi juga bertujuan untuk meningkatkan kesadaran dan mengubah perilaku untuk mencapai kesehatan dan gizi yang optimal. Edukasi, pretest, dan posttest terkait informasi nilai gizi diberikan kepada 26 siswa SMAN 5 Mataram yang tergabung dalam kelompok UKS dan PMR. Hasil kegiatan menunjukkan bahwa pengetahuan dan kemampuan membaca label informasi nilai gizi siswa meningkat setelah diberikan edukasi. Dengan demikian, pemberian edukasi ini memberikan hasil yang positif. Melalui kegiatan ini, kami berharap para siswa semakin sadar dan mampu memilih jajanan sehat untuk mencapai gizi yang optimal.
PENENTUAN KADAR LEMAK PADA TEPUNG TERIGU DAN TEPUNG MAIZENA MENGGUNAKAN METODE SOXHLET FARIDA ARIANI; SOFIA ROHANI; NI MADE WIASTY SUKANTY; LINA YUNITA; NOVIA ZURIATUN SOLEHAH; BAIQ IKE NURSOFIA
GANEC SWARA Vol 18, No 1 (2024): Maret 2024
Publisher : Universitas Mahasaraswati K. Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35327/gara.v18i1.747

Abstract

Fat is one of the important components in food that provides texture and taste. Flour is a food ingredient made from grinding tubers, grains, and stems (sago). This research aimed to determine the difference in fat content in bulk wheat flour (without label), wheat flour (high protein, labeled), and cornstarch. The fat content of a food can be determined by extracting the fat. The fat content analysis method in this research used the Soxhlet method, which can extract fat with the nonpolar organic solvent n-hexane using a soxhlet extractor. The highest fat content was obtained in the wheat flour sample (high protein, labeled) at 2.29%, followed by bulk wheat flour at 1.32%, and cornstarch at 0.65%. The differences of fat content in flour can be caused by the variations of fat content in the raw materials that used in produced flour
HUBUNGAN ASUPAN ZAT GIZI MAKRO DENGAN STATUS GIZI ANAK SEKOLAH DASAR DI WILAYAH PESISIR KOTA MATARAM LINA YUNITA; NI MADE WIASTY SUKANTY; FARIDA ARIANI
GANEC SWARA Vol 17, No 4 (2023): Desember 2023
Publisher : Universitas Mahasaraswati K. Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35327/gara.v17i4.657

Abstract

Nutritional problems can be in the form of macronutrient problems and micronutrient problems. One group that requires attention in consuming food and nutrients is school-aged children. School age children are children aged 6-12 years where they experience the second growth spurt after toddlerhood. School-aged children on the coast are a group that is at high risk of experiencing nutritional status problems. Adequate nutritional intake is very influential for optimal growth, development and children's health. This study aims to determine the relationship between macronutrient intake and the nutritional status of elementary school children in the coastal area of Mataram City. The method used in this research is an analytical survey with a cross sectional design and using a total sampling method. The number of samples used was 140 students in grades IV and V at SDN 18 and 38 Ampenan. Nutritional intake data was obtained through the Recall questionnaire, while nutritional status data was obtained from BMI calculations obtained from measuring height and weight. Research data was processed using the Spearman correlation test with a value of α = 0.05. The test results show the p value = 0.000. Based on these results, it can be concluded that there is a significant relationship between energy, protein, fat and carbohydrate consumption patterns and nutritional status.
ANALISIS GOOD MANUFACTURING PRACTICES (GMP) DI PANTI SOSIAL LANJUT USIA MANDALIKA INDAH KARLINA; NOVIA ZURIATUN SHOLEHA; LINA YUNITA
GANEC SWARA Vol 18, No 4 (2024): Desember 2024
Publisher : Universitas Mahasaraswati K. Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35327/gara.v18i4.1154

Abstract

Diseases transmitted through food or WHO calls them food-borne diseases (Food Borne Diseases) are infectious diseases or poisoning caused by microbes or agents that enter the body through the food consumed.  This research aims to find out how GMP is implemented in food management at the Mandalika Social Home for the Elderly and recommend follow-up actions.  This qualitative research uses a descriptive analysis approach.  This research uses informants, namely nutritionists, as providers of information regarding the situation and conditions of the research setting with instruments as interview tools.  Data analysis in this research uses the GAP Analysis method, namely to analyze the gaps that occur in the implementation of GMP at the Mandalika Elderly Social Home followed by recommending follow-up actions on aspects that have a low average score.  This research shows that the implementation of GMP in the Mandalika Social Home for the Elderly is 79.59% with the highest implementation being in the aspects of materials, final products and packaging, namely 100%, while the lowest implementation is in the laboratory aspect, labels and product descriptions, training and record keeping with percentages by 40%.
UJI TOKSISITAS EKSTRAK ETANOL DAUN RENGGAK (Amomum dealbatum) SEBAGAI BIOLARVASIDA LARVA NYAMUK Aedes aegypti Farida Ariani; Ni Made Wiasty Sukanty; Lina Yunita
Jurnal Inovasi Teknik Kimia Vol 9, No 4 (2024)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v9i4.11775

Abstract

Demam Berdarah Dengue (DBD) merupakan penyakit disebabkan oleh virus dengue yang dapat ditularkan ke manusia melalui gigitan nyamuk Aedes aegypti. Jumlah kasus DBD yang dilaporkan oleh World Health Organization (WHO) semakin meningkat dari 2,5 juta pada tahun 2010 menjadi 4,2 juta pada tahun 2019. Pada tahun 2021, WHO memperkirakan jumlah infeksi DBD secara global sekitar 100-400 juta setiap tahunnya. Penggunaan larvasida kimia secara terus menerus dapat menimbulkan pencemaran lingkungan dan resistensi pada organisme target. Alternatif untuk mengatasi masalah tersebut adalah menggunakan larvasida alami dengan memanfaatkan senyawa aktif pada tanaman yaitu daun Renggak (Amomum dealbatum). Tujuan dari penelitian ini adalah untuk mengetahui perbandingan efektifitas ekstrak daun Renggak dengan abate (temephos) terhadap jumlah kematian larva Aedes aegypti. Jenis rancangan dalam penelitian ini adalah Posttest Only Control Group Design, yang merupakan penelitian True Experimental. Hasil penelitian menunjukkan bahwa ekstrak daun Renggak memiliki efek larvasida terhadap larva Aedes aegypti. Perbandingan perlakuan antara penggunaan ekstrak daun Renggak dan abate menunjukkan efektifitas yang sama terhadap larva Aedes aegypti setelah 12 jam perlakuan. Nilai LC50 ekstrak etanol daun Renggak terhadap mortalitas larva diperoleh pada konsentrasi 0,3% yang berarti bahwa pada konsentrasi 0,3% ekstrak etanol daun renggak mampu membunuh 50% larva Aedes aegypti.
Co-Authors A. Suyatni Musrah Andi Asliana Sainal Baiq Fitria Rahmiati BAIQ IKE NURSOFIA Farida Ariani Farida Ariani Fauziah H. Tambuala I Gde Narda Widiada I Nyoman Adiyasa I Putu Bayu Agus Saputra INDAH KARLINA Irwan Cahyadi Kristiandi, Kiki Lalu Juntra M. Thonthowi Jauhari M. Zulfikar Al Fariqi Ni Made Wiasty Sukanty NOVIA ZURIATUN SHOLEHA Novia Zuriatun Solehah NOVIANTI TYSMALA DEWI Novianti Tysmala Dewi Novianti Tysmala Dewi Rahmiati, Baiq Fitria Rasi Rahagia Regina Pricilia Yunika Reni Sofiyatin SOFIA ROHANI Suprapto Suprapto Wayan Canny Naktiany Widani Darma Isasih Widarta Widarta Wiwin Lastyana