Garuda - Garba Rujukan Digital

Hubungan antara Lamanya Aktivitas Melihat Dekat dengan Miopia pada Anak di SDN Cemara 2 Surakarta Purbaningrum, Eli Dwy; Indrakila, Senyum; Primadewi, Novi
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Background: The most common type of refractive error in school student was myopia. Some factors are predicted play a role in the onset of myopia, one of them is nearwork activity. Meanwhile, the globalization encourages children to do some nearwork activities, such as reading and using gadgets. The purpose of this study was to analyze the the relationship between duration of nearwork activity and children myopia. Methods: This study used observational analytic method with cross-sectional design research. The population was all students of SDN Cemara 2 Surakarta. Subjects were students of grade III to V who are either suffering myopia or not. The total subject were 200 children, which was 100 children with myopia picked by fixed disease sampling technique, and 100 children with no myopia picked by simple random sampling technique. The data were collected by measurement with autorefractometre and questionnaires. The data obtained were analyzed by using multiple logistic regression with SPSS 17.0 for Windows. Result: From 200 subjects found that total children myopia who do nearwork activities longer 54 (52%) and children with no myopia who do nearwork activities longer 50 (48%). The results of multiple logistic regression statistical test showed that duration of nearwork activity and children myopia have no significant relationship statistically (p = 0,59). Conclusion: There was no significant relationship between duration of nearwork activity and children myopia.Â

Hubungan antara lama paparan bising terhadap gangguan pendengaran pada instruktur drum Primadewi, Novi; Kandhi, Putu Wijaya; Azizah, Zahroh Zuliana
Oto Rhino Laryngologica Indonesiana Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018
Publisher : PERHATI-KL

Latar belakang: Alat musik drum merupakan alat musik yang memiliki nilai kebisingan. Instruktur drum dapat terpapar bising yang tinggi, sehingga dapat mengalami gangguan pendengaran. Tujuan: Mengetahui hubungan antara lama paparan bising terhadap gangguan pendengaran pada instruktur drum di Surakarta dan sekitarnya. Metode: Jenis penelitian yang digunakan adalah obervasional non experimental dengan desain cross sectional pada 71 instruktur drum di 14 sekolah musik di Surakarta. Sampel berupa hasil pemeriksaan audiometri nada murni yang dilaksanakan di studio musik kedap suara dengan NAB kurang dari 40 Dba SPL. Data dianalisis menggunakan uji statistik Chi Square. Hasil analisis statistik bermakna bila didapatkan nilai p=0,001<0,01. Hasil: Pada rerata tingkat kebisingan yang terukur dengan alat Sound Level Meter di 14 sekolah musik di Surakarta. Pada saat memainkan drum adalah sebesar 111,48±3,84 dB. Terdapat responden dengan durasi ≤2 jam tanpa GPAB sebanyak 10 orang (14,1%) dan paling banyak terjadi dengan GPAB pada durasi >4 sampai dengan 6 jam sebanyak 38 orang (51,2%). Nilai p=0,001<0,01 yang berarti ada hubungan yang bermakna antara durasi dengan GPAB pada instruktur drum dengan coefficient of contingency CC sebesar 0,687 (68,70%). Kesimpulan: Terdapat hubungan antara lama paparan bising terhadap gangguan pendengaran pada instruktur drum. Background: Drum is one of musical instruments producing a high level of noise. Drum instructors are exposed to this loudness, which might give them a high risk of hearing impairment. Objective: To investigate the correlation between loudness exposure time and hearing impairment of drum instructors in Solo area. Methods: This was an observational non experimental research using cross sectional design on 71 drum instructors in 14 music schools in Surakarta. The samples were the result of pure tone audiometry examination conducted in a soundproof music studio with NAB less than 40 Dba SPL. Data were analyzed using Chi Square statistical tests. The results of statistical analysis were significant if p = 0.001 <0.01. Result: The average noise level measured by a Sound Level Meter tool in 14 music schools in Surakarta, while playing the drum was 111.48 ± 3.84 dB. There were respondents with a duration of ≤ 2 hours without Noise Induce Hearing Loss (NIHL) as many as 10 people (14.1%), and the highest occurence with NIHL was at a duration of >4 to 6 hours as many as 38 people (51.2%). The value of p = 0.001 <0.01, revealed that there was a significant correlation between the duration of noise exposure and NIHL in drum instructors with coefficient of contingency (CC) of 0.687 (68.70%). Conclusion: Noise exposure time was correlated with hearing impairment in drum instructors.

Hubungan Tinggi Badan menurut Umur dengan Kejadian Miopia pada Anak di SDN Cemara Dua Surakarta Aprillia, Wahyu; Indrakila, Senyum; Primadewi, Novi
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Background: Myopia is one of refractive errors most often occurs in children. Axial length appears to be a major determinant of refractive error. It has been theorized that a larger body might be associated with a greater axial length (AL) simply as a function of larger overall body size. Some studies suggest that taller people were more myopic than short people. This study aimed to analyze the relationship between height for age with myopia in children atÂ SDN Cemara Dua Surakarta. Methods: An analytical observational study using a cross sectional design, was performed in Cemara Dua Surakarta Elementary School on May-June 2013. Total respondents were 180 people, taken by fixed disease sampling. Height for age was determined by respondents height z-score analysis that adjusted for TB/U growth chart based on WHO child growth standard. Status myopia obtained by screening using autorefractometer. Analysis of data was bivariate chi square, using SPSS program version 20.0 for windows. Results: This study shows 6 (3,3%) subject were stunted, 163 (90,6%) subject were normal, and 11 (6,1%) subject were heigt. Number of taller children in myopia were 7 people (63.6%) and not myopia were 4 people (36.4%). Chi Square test showed the results of p value = 0.351 (p < 0,05). Conclusions: There is no relationship between height for age with myopia in children at SDN Cemara Dua Surakarta. Keywords: Height, Age, Myopia.Â

THE EFFECT OF GINKGO BILOBA AGAINST OTOTOXIC HEARING LOSS ON ADVANCED STAGE UNDIFFERENTIATED NASOPHARYNGEAL CARCINOMA RECEIVING CISPLATIN CHEMOTHERAPY Hendriyanto, Donny; Setiamika, Made; Primadewi, Novi
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 2 No. 02 (2020): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v2i02.3910

Abstract Introduction: Undifferentiated nasopharyngeal carcinoma is the most common malignant tumor in nasopharynx, in which most patients come to a hospital in advanced stage. Cisplatin is one of the most effective widely used chemotherapy drugs for advanced stage undifferentiated nasopharyngeal carcinoma. Although it provides a successful outcome against cancer, there is serious side effect namely ototoxic hearing loss. Ginkgo biloba is a powerful antioxidant which may prevent ototoxic hearing loss. Objective: The study aims to determine the effect of ginkgo biloba against ototoxic hearing loss on advanced stage undifferentiated nasopharyngeal carcinoma receiving cisplatin chemotherapy. Methods: This study was double blind Randomized Control Trial with pre-post test design, was conducted in 22 patients with advanced stage undifferentiated nasopharyngeal carcinoma receiving cisplatin chemotherapy at the Department of Otorhinolaryngology Head and Neck Surgery dr. Moewardi Hospital Surakarta between June 1st and October 1st 2019. The subjects were allocated into control (plasebo) and treatment (80 mg Ginkgo biloba extract) groups. Hearing function was examined with pure tone audiometry, tympanometry and Distortion Product Otoacoustic Emission before and after the first, the second and the third cisplatin chemotherapy. The results of the examination of the two groups were tested using Friedman and Chi Square test. P value of <0.05 was considered significant. Results: The study subjects were mostly male (63.6%), with the age range of 40-59 years (90.9%). The baseline characteristics of the study subjects were homogeneous (p>0.05). There was a significant difference in the incidence of ototoxic hearing loss between control and treatment group after getting the second and the third chemotherapy (p=0.043 and p=0.033, respectively). Conclusion: There is a significant effect of ginkgo biloba in term of preventing ototoxic hearing loss on advanced stage undifferentiated nasopharyngeal carcinoma patients receiving cisplatin chemotherapy.

GANGGUAN PENDENGARAN AKIBAT BISING PENGGUNAAN HEADPHONE/EARPHONE: Noise Induce Hearing Loss Due to Usage of Headphone/Earphone Hendradewi, Sarwastuti; Setiamika, Made; Sudrajad, Hadi; Kandhi, Putu Wijaya; Primadewi, Novi; Pratiwi, Dewi; Yusuf, Destar Aditya
Jurnal Pengabdian Masyarakat Medika Vol 3. No. 2, September 2023
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v3i2.1274

ABSTRAK Gangguan pendengaran akibat bising (GPAB) sering dijumpai pada usia pelajar. Adanya kemajuan alat elektronik beserta kemudahan dalam mengakses internet dan sosial media menyebabkan pelajar sering menggunakan personal listening device seperti headphone/earphone untuk mengakses informasi dari piranti elektronik tersebut. Identifikasi gangguan pendengaran secara dini dan intervensi yang sesuai terbukti dapat mencegah konsekuensi tersebut. Tujuan diselenggarakan kegiatan ini adalah untuk memberikan edukasi gangguan pendengaran akibat bising (GPAB) dan untuk mengetahui sejak dini kondisi telinga dan pendengaran pelajar dan memberikan intervensi dan tatalaksana sesuai kebutuhan. Metode dalam kegiatan ini direncanakan dilakukan melalui tahapan - tahapan sesuai dengan petunjuk pengendalian HIRARC (hazard identification, risk assessment, and risk control). Hasil kegiatan ini didapatkan pendengaran 147 siswa dalam batas normal, 31 siswa terdapat serumen, 7 siswa Otitis Eksterna, 3 siswa OMSK, dan 4 orang siswa dicurigai menderita gangguan pendengaran akibat bising. Siswa yang dicurigai menderita gangguan pendengaran akibat bising dianjurkan ke RSUD Dr. Moewardi Surakarta untuk dilakukan pemeriksaan dan tatalaksana lebih lanjut. ABSTRACT Noise induce hearing loss (NIHL) is often found in students. The advancement of electronic devices along with the ease of accessing the internet and social media has caused students to often use personal listening devices such as headphones/earphones to access information from these electronic devices. Early identification of hearing loss and appropriate intervention have been shown to prevent such consequences. The purpose of this activity was to educate noise induce hearing loss (NIHL) and to know early on the ear and hearing condition of students and provided intervention and management as needed. The method in this activity was planned to be carried out through stages in accordance with the HIRARC (Hazard Identification, Risk Assessment, and Risk Control) control instructions. The results of this activity obtained the hearing of 147 students within normal limits, 31 students with cerumen, 7 Otitis Externa students, 3 OMSK students, and 4 students with suspect of noise induce hearing loss. Students who were suspected of suffering from hearing loss due to noise were recommended to Dr. Moewardi Surakarta Hospital for further examination and management.

Correlation between duration of chronic renal failure patients undergoing hemodialysis and sensorineural hearing loss Primadewi, Novi; Pratiwi, Dewi; Dewi, Taufani
Oto Rhino Laryngologica Indonesiana Vol. 52 No. 2 (2022): VOLUME 52, NO. 2 JULY - DECEMBER 2022
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v52i2.453

ABSTRACTBackground: Along with the increasing incidence of chronic renal failure patients receiving hemodialysis, recently, the incidence of sensorineural hearing loss (SNHL) among patients with end-stage kidney disease undergoing hemodialysis had also increased. The cochlea and kidney have many anatomical, physiological, pharmacological and pathological similarities. Dialysis sometimes causes worsening of hearing function. Objective: To determine the correlation between the duration of renal failure patients undergoing hemodialysis and the degree of sensorineural hearing loss. Method: A retrospective study using cross sectional method, conducted from August–September 2018. The study began by identifying patients with chronic renal failure and then continued with Oto Acoustic Emission (OAE) examination and pure tone audiometry. Result: The results of the Spearman rank statistical test for the correlation between duration of hemodialysis and the degree of SNHL in the right and left ears in patients with chronic renal failure found a significant positive correlation r= 0.498 and p=0.001 (right) , and r= 0.400 and p=0.006 (left). Conclusion: There was a significant correlation between the length of hemodialysis and the degree of sensorineural hearing loss. ABSTRAKLatar belakang: Seiring dengan peningkatan angka kejadian pasien gagal ginjal kronik yang mendapatkan hemodialisa, akhir-akhir ini didapati peningkatan angka kejadian Sensorineural Hearing Loss (SNHL) di antara pasien dengan penyakit ginjal stadium akhir yang menjalani hemodialisa. Koklea dan ginjal memiliki banyak kesamaan anatomis, fisiologis, farmakologis dan patologis. Dialisa terkadang menyebabkan memburuknya fungsi pendengaran. Tujuan: Untuk mengetahui hubungan lama pasien gagal ginjal yang menjalani hemodialisa dengan derajat gangguan pendengaran tuli sensorineural. Metode: Penelitian retrospektif dengan metode potong lintang, dilakukan dari Agustus-September 2018. Penelitian dimulai dengan mengidentifikasi pasien gagal ginjal kronik kemudian dilanjutkan dengan pemeriksaan tes Oto Acoustic Emission (OAE) dan audiometri nada murni. Hasil: Hasil uji statistik Spearman rank untuk korelasi lama hemodialisa dengan derajat SNHL telinga kanan dan kiri pada pasien gagal ginjal kronik didapatkan korelasi positif yang signifikan: r= 0,498 dan p=0,001 (kanan) dan r= 0,400 dan p=0,006 (kiri). Kesimpulan: Terdapat korelasi yang bermakna antara lama hemodialisis dengan derajat tuli sensorineural.

Adaptation of Chronic Otitis Media Questionnaire (COMQ-12): reability and validity of the Indonesian version Sudrajad, Hadi; Hendradewi, Sarwastuti; Primadewi, Novi; Kandhi, Putu Wijaya; Seytopambudi, Kukuh
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i2.688

Background: Chronic suppurative otitis media (CSOM) is one of the most common ear diseases that has a major impact on quality of life (QoL). The Chronic Otitis Media Questionnaire 12 (COMQ-12) is a CSOM-specific questionnaire that aims to assess QoL. Until currently, there is no questionnaire that has been tested for reliability and validity in the Indonesian version. Purpose: To assess the reliability and validity of the Indonesian version of COMQ-12. Method: An analytic observational study with a cross-sectional design, conducted in Dr. Moewardi General Hospital Surakarta Indonesia from March to May 2024. Reliability was assessed by internal consistency, and validity was assessed by Pearson correlation. Result: The reliability test with internal consistency obtained Cronbach’s alpha value for all question items >0.7. This indicated that all question items had good reliability. Meanwhile, the validity test with the Pearson correlation test obtained a p-value <0.05 for all question items with coefficients, all of which were positive. This indicated that all question items had good validity. Conclusion: Indonesian version of COMQ-12 has good reliability and validity to assess QoL in CSOM patients. Keywords: CSOM, COMQ-12, QoL, reliability, validity ABSTRAK Latar belakang: Otitis media supuratif kronik (OMSK) merupakan salah satu penyakit telinga yang paling umum dijumpai, dan berdampak besar pada kualitas hidup (QoL). Kuesioner Otitis Media Kronik 12 (COMQ-12) merupakan kuesioner khusus Otitis Media Supuratif Kronik (OMSK) yang bertujuan untuk menilai QoL, namun saat ini kuesioner COMQ-12 dalam versi Bahasa Indonesia belum teruji reliabilitas dan validitasnya. Tujuan: Untuk menilai reliabilitas dan validitas COMQ- 12 versi Bahasa Indonesia. Metode: Penelitian observasi analitik dengan desain potong lintang, yang dilakukan di RSUD Dr. Moewardi Surakarta, Indonesia dari bulan Maret sampai Mei 2024. Reliabilitas dinilai dengan konsistensi internal, dan validitas dinilai dengan korelasi Pearson. Hasil: Uji reliabilitas dengan konsistensi internal memperoleh nilai Cronbach’s alpha untuk semua butir soal >0,7. Hal ini menunjukkan bahwa semua butir soal memiliki reliabilitas yang baik. Sementara itu, uji validitas dengan uji Pearson correlation memperoleh nilai p<0,05 untuk semua butir soal, dengan koefisien yang semuanya positif. Hal ini menunjukkan bahwa semua butir soal memiliki validitas yang baik. Kesimpulan: COMQ-12 versi Indonesia mempunyai reliabilitas dan validitas yang baik untuk menilai kualitas hidup pasien OMSK.

Antioxidant Ability of the 2% Indonesian Mount Lawu Propolis Ear Drops Sudrajad, Hadi; Setiamika, Made; Hendradewi, Sarwastuti; Primadewi, Novi; Kandhi, Putu Wijaya; Pratiwi, Dewi; Kesumo, Aningdita; Pratiwi, Primadita Asis
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i1.53208

Propolis ear drops are natural antioxidants that have been developed for various health purposes. There are many types of propolis ear drops available today, including the Indonesian Mount Lawu Propolis ear drop (IMLPED). Indonesian Mount Lawu Propolis ear drop is proven to contain many antioxidant substances such as flavonoids, phenolic acids, caffeic acid pethyl ester, and quercetin. However, to date, no study has assessed the antioxidant activity of IMLPED, especially the 2% IMLPED. This study aims to assess the antioxidant activity of the 2% IMLPED. This is an in vitro study to assess the antioxidant activity of the 2% IMLPED with 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) method based on the inhibitory concentration at 50% (IC50) value. The IC50 represents the concentration required to reduce 50% of the free radicals. The result of this study showed that the IC50 value of the 2% IMLPED is 30.71 µg/mL. Based on the IC50 value, the 2% IMLPED formula exhibits a robust antioxidant effect. The implications of this revelation establish IMLPED as a promising candidate in combating oxidative stress.

PENEGAKAN DIAGNOSIS NEUROPATI AUDITORI : SEBUAH LAPORAN KASUS Primadewi, Novi; Anggraini, Rinda Putri; Aditya, Destar
Indonesian Basic and Experimental Health Sciences Vol. 12 No. 1 (2023): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol12iss1pp41-54

PENDAHULUAN Neuropati auditori merupakan bagian dari tuli sensorineural, dimana suara dapat masuk hingga telinga dalam, tetapi transmisi sinyal dari telinga dalam ke otak terganggu pada jaras tertentu. Evaluasi klinis serta pemeriksaan yang tepat dibutuhkan pada penegakkan diagnosis neuropati auditori sehingga tatalaksana yang tepat dapat segera diberikan. LAPORAN KASUS Dilaporkan seorang anak laki-laki umur 1 tahun 8 bulan dengan keluhan belum dapat bicara sesuai usianya dan tidak respon terhadap panggilan ataupun suara keras. Pasien mempunyai riwayat hiperbilirubinemia pada usia 2 minggu. Pasien dilakukan pemeriksaan OAE dengan hasil normal, ABR/BERA terdapat gelombang mikroponik koklea pada intensitas 90-95 dB dan tidak tampak gelombang V pada intensitas 70-95 dB dan ASSR hasil ambang dengar gangguan derajat berat. DISKUSI Diagnosa neuropati auditori dapat ditegakkan dengan pemeriksaan Otoacoustic Emission (OAE) dengan hasil fungsi sel rambut luar koklea normal dan pada auditory brainstem respons (ABR/BERA) didapatkan Cochlear Microphonic (CM) normal atau pernah ada dalam satu waktu tetapi respons gelombang tidak normal atau tidak ada. Pada kasus ini telah dilakukan penegakan diagnosis yang sesuai dengan panduan. KESIMPULAN Diagnosa neuropati auditori dapat ditegakkan dengan pemeriksaan Otoacoustic Emission (OAE) dengan hasil fungsi sel rambut luar koklea normal dan pada auditory brainstem respons (ABR/BERA) didapatkan Cochlear Microphonic (CM) normal atau pernah ada dalam satu waktu tetapi respons gelombang tidak normal atau tidak ada.

The Effect Of Administration Of Mecobalamin & Curcumin As Antioxidants In Nasopharynx Carcinoma Patients Post Cisplatin Regimen Chemotherapy With Hearing Impairment Matea, Ari; Primadewi, Novi
Indonesian Basic and Experimental Health Sciences Vol. 13 No. 1 (2024): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol13iss1pp1-6

INTRODUCTION Nasopharyngeal carcinoma (NPC) is a common type of cancer in Southeast Asia, and its treatment often involves a cisplatin chemotherapy regimen. Ototoxicity is a side effect that often occurs in patients receiving this regimen. Antioxidant therapy, both synthetic and natural, such as curcumin, has been studied as having the potential to reduce ototoxicity due to cisplatin. This study was conducted to evaluate the effect of administering mecobalamin and curcumin as antioxidants in patients with nasopharyngeal carcinoma after cisplatin chemotherapy regimen with hearing loss. METHOD This study was an observational study with a cross sectional design, using consecutive sampling with inclusion criteria, namely patients diagnosed with NPC receiving the cisplastin regimen and willing to take part in the study. The data obtained was then analyzed using the Rank-Biserial Correlation's Test. Research approval was obtained from the Medical Research Ethics Commission, Faculty of Medicine, Sebelas Maret University/RSUD Dr. Moewardi Surakarta. RESULTS Of the 30 NPC patients who received cisplatin from the ENT-KL installation section of Dr Moewardi Hospital in the period March - September 2023, 30 data were obtained for each right ear and left ear. The average hearing threshold before intervention was 33.79 ± 10.40 dB and 34.10 ± 9.75 for the right and left ears. There was a difference in the average increase in hearing threshold for all parameters (Group I: Mecobalamin, Group II: Curcumin, Group III: Curcumin + Mecobalamin), with a value of p=0.000 (p<0.05). From these data it was concluded that the combined therapy of both was able to increase the hearing threshold along with the chemotherapy series. CONCLUSION Based on the research results, administration of mecobalamin and curcumin as antioxidants has a significant effect on patients with nasopharyngeal carcinoma after cisplatin chemotherapy regimen with hearing loss.

Title

Found 21 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 21 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 21 Documents
Search