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Evaluasi Waktu Tunggu Pelayanan Resep Obat Racikan dan Non Racikan pada Pasien Rawat Jalan di Apotek Depi Yuliana; Faizul Bayani; Dedent Eka Bimmaharyanto; Lelie Amalia Tusshaleha; Syamsul Rahmat; Meilynda Pomeistia; Recta Olivia Umboro
Bioscientist : Jurnal Ilmiah Biologi Vol 9, No 2 (2021): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v9i2.4950

Abstract

The quality of health services is still not optimal, especially in terms of patient dissatisfaction with drug services at pharmacies. A more efficient system can be built only if the waiting time evaluation has been carried out at pharmacies that provide drug prescriptions for patients. This study aims to evaluate the waiting time for prescription services at pharmacies to achieve patient satisfaction with drug services at pharmacies. In this study, Angkasa Farma's pharmacy became the subject of evaluation. The study was conducted with an observational design using descriptive analysis. The waiting time data obtained were then analyzed descriptively and compared with the minimum service standard of waiting time, this is for two types of drugs (prepared drugs and compound drugs). The results of the study based on a sample of 100 recipes and 100 non-concoction recipes are the number of recipes that meet the standards for prescription recipes as many as 37 recipes and for non-concoction recipes as many as 95 recipes. The average waiting time for concoction recipe services is 41.47 minutes and the average waiting time for non-concoction prescription services is 21.29 minutes. The average waiting time for non-concoction prescription services has met the standard, while the waiting time for blended prescription services has not met the standards according to the Regulation of the Minister of Health of the Republic of Indonesia.
Phytochemical Identification of Ethanol Extract of Mahkota Dewa Fruit Flesh (Phaleria macrocarpa [Scheff]) as Antidiabetic Depi Yuliana; Faizul Bayani; Dwi Monika Ningrum; Neneng Rachmalia Izzatul Mukhlishah
SainsTech Innovation Journal Vol. 3 No. 1 (2020): SIJ Volume 3 Nomor 1 Mei 2020
Publisher : LPPM Universitas Qamarul Huda Badaruddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (458.116 KB)

Abstract

Diabetes mellitus (DM) is one of the biggest disease problems in the world. World Health Organization (WHO) as many as 346 billion people in the world are indicated to have DM. Phaleria macrocarpa [Scheff] Boerl as a native Indonesian medicine is widely used in traditional medicine as an effective medicine against DM, cancer, gout, high cholesterol, and kidney disorders. Phaleria macrocarpa [Scheff] Boerl has saponins and tannins which play a role in reducing blood glucose levels. This study aims to identify the metabolite compounds of Phaleria macrocarpa [Scheff] Boerl extract that have the potential to be anti-diabetic. The research using the TLC method. The results of TLC showed that Phaleria macrocarpa [Scheff] Boerl extract has flavonoids, alkaloids, saponins and tannins.
Identifikasi Penyebab ADR (Adverse Drug Reactions) pada Pasien CHF (Congestive Heart Failure) Depi Yuliana; Putri Ramdaniah; Faizul Bayani; Dedent Eka Bimmaharyanto S.; Dita Marina Lupitaningrum
Lensa: Jurnal Kependidikan Fisika Vol 9, No 1: June 2021
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (705.339 KB) | DOI: 10.33394/j-lkf.v9i1.4264

Abstract

Congestive Heart Failure (CHF) adalah salah satu masalah kesehatan yang progresif dengan angka mortalitas maupun morbiditas yang tinggi dan berpotensi terjadi ADRs (adverse drug reactions). Resiko ADRs pada pasien CHF berkaitan dengan regimen obat yang kompleks dan banyaknya komorbiditas pada pasien tersebut. Penelitian ini dilakukan untuk mengukur kausalitas dan menganalisis obat dan jenis ADRs yang paling sering terjadi. Penelitian ini termasuk retrospective study dengan data penelitian yang digunakan adalah data pasien CHF yang menjalani rawat inap RSUD Provinsi NTB dari tahun 2017 sampai 2019. Penilaian kausalitas ADRs menggunnakan skala WHO-UMC. Data pasien CHF yang digunakan dalam penelitian ini sebanyak 325 pasien. Sebanyak 223 pasien (68,6%) tercatat mengalami ADRs dengan hasil penilaian kausalitas menggunakan WHO-UMC antara lain 8 (1,8%) certain, 178 (39,9%) probable/likely, dan 260 (58,3%) possible. Obat yang paling banyak menimbulkan ADRs dengan status kausalitas certain adalah ramipril yang menimbulkan batuk. Kesimpulan: sebagian besar ADRs yang terjadi pada pasien CHF adalah possible dan jenis obat yang paling tinggi menimbulkan ADRs adalah ramipril sehingga penggunaan ramipril perlu lebih diperhatikan karena termasuk highly probable dalam menimbulkan ADRs.Identification of The Causality of ADR (Adverse Drug Reactions) in CHF (Congestive Heart Failure) PatientsAbstractCongestive Heart Failure (CHF) is a progressive health problem with high mortality and morbidity rates and the potential for ADRs (adverse drug reactions). The risk of ADRs in CHF patients is related to the complex drug regimen and the many comorbidities in these patients. This study was conducted to measure causality and analyze the most common drugs and types of ADRs. This study includes a retrospective study with the research data used is data on CHF patients who underwent hospitalization at the NTB Provincial Hospital from 2017 to 2019. The causality assessment of ADRs used the WHO-UMC scale. Data on CHF patients used in this study were 325 patients. A total of 223 patients (68.6%) were recorded to have ADRs with the results of a causality assessment using WHO-UMC including 8 (1.8%) certain, 178 (39.9%) probable/likely, and 260 (58.3%) possible. The drug that causes the most ADRs with certain causality status is ramipril which causes coughing. Conclusion: most of the ADRs that occur in CHF patients are possible and the type of drug that causes the highest ADRs is ramipril so that the use of ramipril needs to be paid more attention because it is highly probable in causing ADRs.
Studi Adverse Drug Reactions Penggunaan Obat Antiepilepsi Monoterapi Pada Anak di Rumah Sakit - Studi Farmakovigilans Putri Ramdaniah; Dwi Monika Ningrum; Depi Yuliana; Dedent Eka Bimmahariyanto S.; Recta Olivia Umboro
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.8384

Abstract

ABSTRAKPengobatan epilepsi membutuhkan waktu yang lama, penghentian terapi dilakukan secara bertahap apabila dicapai bebas kejang selama dua tahun. Pengobatan yang bersifat jangka panjang dikaitkan dengan peningkatan efek samping dan membutuhkan monitoring pengobatan. Pasien anak sering mengalami efek samping obat yang sama dengan pasien dewasa, namun reaksi obat yang tidak dikehendaki pada pasien anak lebih sulit karena perbedaan karakteristik antara pasien anak dan pasien dewasa juga mempengaruhi efikasi dan efek samping obat. Tujuan penelitian ini untuk menghitung angka kejadian ADRs dan Klasifikasi Jenis ADRs pada penggunaan obat antiepilepsi Monoterapi. Metode yang digunakan yaitu penelitian cross sectional dengan pengambilan data secara prospektif, penilaian kausalitas ADRs menggunakan algoritma naranjo, selama periode penelitian didapatkan 56 pasien yang mendapatkan terapi monoterapi dari total 86 pasien. jenis-jenis ADRs yang terjadi pada pasien yaitu gangguan gastrointestinal 32,35%, reaksi kulit gatal dan kemerahan terjadi 7,35%, gangguan metabolik sebanyak 10,29%, dan gangguan CNS (Central nervous system) sebanyak 10,29%. Kata kunci : Adverse drug reactions; Antiepilepsi; Anak-anak.ABSTRACTEpilepsy treatment takes a long time, discontinuation of therapy is carried out gradually if achieved without seizures for two years. Treatment is long-term treatment with increased side effects and requires medication monitoring. Pediatric patients often experience the same side effects of drugs as adults, but adverse drug reactions in pediatric patients are more difficult because differences in characteristics between patients and adult patients also affect the efficacy and side effects of drugs. The purpose of this study was to calculate the incidence of ADR and Classification of Types of ADR in the use of monotherapy antiepileptic drugs. The method used is a cross sectional study with prospective data collection, ADR Causality Assessment using the Naranjo Algorithm, during the study period 56 patients received monotherapy therapy from a total of 86 patients. The types of ADR that occur in patients are gastrointestinal disorders 32.35%, itching and skin reactions that occur 7.35%, metabolic disorders as much as 10.29%, and CNS (Central Nervous System) disorders as much as 10.29%.Keywords : Adverse drug reactions; Antiepileptic; Pediatric.