Lely Retno W
Department Of Ophthalmology, Universitas Brawijaya, Dr. Saiful Anwar General Hospital, Malang, East Java, Indonesia

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The Etiology of Paralytic Strabismus at an Indonesian Tertiary Hospital from 2017 to 2022 Azizah, Aulia Rachma Nur; Loebis, Rozalina; Hidayati, Hanik Badriyah; Wahyuni, Indri; Wulandari, Lely Retno
Folia Medica Indonesiana Vol. 60, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Highlights: 1. This study investigated the etiology of paralytic strabismus, a condition that requires further research to prevent its incidence, particularly in adults. 2. The findings of this study provided valuable insight into the primary etiology of paralytic strabismus and its underlying factors. Abstract Paralytic strabismus is the most common cause of adult-onset strabismus. It can result from paralysis of the third, fourth, or sixth cranial nerves, either separately or in combination, which are responsible for innervating the ocular motor muscles. Paralysis of these cranial nerves occurs due to congenital disorders, neoplasms, trauma, intracranial processes, idiopathic diseases, and other causes. This study aimed to determine the etiology of paralytic strabismus incidence at the Department of Ophthalmology of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, between 2017 and 2022. This study employed a retrospective methodology and utilized total sampling. The medical records of patients diagnosed with paralytic strabismus were used to collect secondary data. Out of the total of 282 cases, the most common condition was combined ocular motor cranial nerve palsy, which accounted for 102 (36.2%) cases. The main factors contributing to this condition were neoplasms (37.2%), intracranial processes (25.5%), trauma (25.5%), other causes (8.8%), idiopathic diseases (2%), and congenital disorders (1%). The incidence of third cranial nerve palsy and sixth cranial nerve palsy was equally prevalent, each accounting for 86 (30.5%) cases. Meanwhile, fourth cranial nerve palsy was the least frequent with just eight (2.8%) cases. This study concluded that the most frequent etiology of paralytic strabismus was combined ocular motor nerve paralysis, which primarily results from neoplasms.
PERBANDINGAN TEKANAN INTRAOKULAR ANAK DENGAN DOWN SYNDROME DAN ANAK TANPA DOWN SYNDROME DI KOTA MALANG Putra, Dani Haritsah; Dewi, Nadia Artha; Anandita, Nanda Wahyu; Wulandari, Lely Retno
Majalah Kesehatan Vol. 12 No. 4 (2025): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/majalahkesehatan.2025.012.04.5

Abstract

Pengukuran tekanan intraokular (TIO) merupakan pemeriksaan untuk menilai kondisi dinamika aqueous humor. TIO dikatakan normal apabila terjadi keseimbangan antara produksi dan outflow dari aqueous humor. Adapun peningkatan TIO dapat merusak struktur bola mata, terutama saraf optik dan sel ganglion retina, serta menjadi faktor risiko penting untuk perkembangan glaukoma. Anak-anak dengan Down syndrome (ADS) memiliki kedalaman bilik mata depan yang lebih dangkal dibandingkan anak-anak tanpa Down syndrome (ATDS) sehingga dapat menyebabkan peningkatan TIO. Oleh karena itu, penelitian ini bertujuan untuk mengetahui perbedaan analisis hasil pengukuran TIO terhadap ATDS dengan ADS. Penelitian ini merupakan penelitian observasional dengan pengambilan data secara cross-sectional terhadap 22 subjek ADS dan 44 subjek ATDS berusia 0-18 tahun yang didapat dari hasil pemeriksaan mata di RSUD dr. Saiful Anwar Kota Malang dan beberapa panti asuhan yang tersebar di Kota Malang. Pada penelitian ini didapatkan bahwa tidak terdapat perbedaan TIO yang signifikan antara ATDS dan ADS pada okuli dekstra (p = 0,065) dan okuli sinistra (p = 0,153). Sehingga dapat disimpulkan bahwa tidak terdapat perbedaan TIO yang signifikan antara ATDS dan ADS, serta tidak didapatkan perbedaan TIO berdasarkan perbandingan intraokular, usia, dan jenis kelamin pada masing-masing kelompok ATDS dan ADS sebagai secondary outcome pada penelitian ini.