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All Journal Jurnal Kedokteran Diponegoro Science Midwifery Indonesian Journal of Global Health research Jurnal Health Sains Cermin Dunia Kedokteran Journal Of World Science Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Puguh Riyanto
Staf Pengajar Bagian Ilmu Kesehatan Kulit Dan Kelamin FK Undip
Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Journal : Science Midwifery

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Comparison of the effectiveness of colloidal oatmeal 1% with petrolatum 100% to repair the skin bars in psoriasis vulgaris: A study of trans-epidermal water loss Riyanto, Puguh; Sugianto, Yosep Ferdinand Rahmat; Z, Mutia Dian Permatasari Mochtar
Science Midwifery Vol 13 No 4 (2025): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2118

Abstract

The purpose of this study was to compare the effectiveness of 1% colloidal oatmeal with 100% petrolatum in improving the skin barrier in patients with psoriasis vulgaris. This research method is a randomized, single-blind, pre and posttest design controlled trial involving patients with mild/moderate/severe psoriasis vulgaris at DR. Kariadi Hospital Semarang, Indonesia. The subjects of the study were divided into 2 groups, namely 1% colloidal oatmeal and 100% petrolatum. Evaluation was carried out by comparing the TEWL values between day 0 and day 28. The analysis was carried out using independent T-tests, Mann Whitney, and Wilcoxon. The results were significant if p<0.05 Results Topical administration of 1% colloidal oatmeal or 100% petrolatum could lower the TEWL value in each study group (p<0.001; p=0.006 respectively). ΔTEWL evaluation showed a significantly greater decrease in TEWL in the 1% colloidal oatmeal group (p=0.003). No complaints during use were reported in the 1% colloidal oatmeal group. Conclusion: Topical application of 1% colloidal oatmeal is more effective than 100% petrolatum as a moisturizer in improving the skin barrier in patients with psoriasis vulgaris without complaints.
Effectiveness of topical combination of finasterid and minoxidil in the management of male androgenetic alopesia (systematic review and meta-analysis: Hair density study) Riyanto, Puguh; Karami, Muhammad Zuldan; Malik, Diah Adriani
Science Midwifery Vol 13 No 4 (2025): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2119

Abstract

Androgenetic alopecia (AAG) is the most common hair loss problem in men, characterized by miniaturization of hair follicles due to systemic androgens and genetic factors. AAG treatment aims to prevent follicle miniaturization Treatment modalities for AAG include hair transplantation, platelet-rich plasma (PRP), microneedling, and stem cells. Each treatment modality has its benefits and risks. The combination of topical finasteride and topical minoxidil has been shown to improve outcomes in several studies. This study aimed to evaluate the efficacy of topical finasteride compared to topical minoxidil in improving hair density among male AAG patients. A systematic literature search method was conducted using MEDLINE, Embase, AMED, Cochrane Library, Clinicaltrials.gov, Web of Knowledge, Web of Science, and WHO ICTRP with the search terms "topical finasteride and minoxidil" 'AND' "male androgenetic alopecia" 'AND' "male pattern hair loss". The literature search was carried out in accordance with the PRISMA 2009 path. Three RCTs were included in the qualitative synthesis and included in the meta-analysis. The results showed that the overall SMD in hair density was 0.751±0.215 (95% CI: 0.331 – 1.162, p<0.001) in favor of topical finasteride and topical minoxidil combination treatment, suggesting that topical finasteride and topical minoxidil combination had much greater effectiveness than control treatments in improving hair density among male patients with AAG.
Co-Authors Adjani, Rima Alexander, Lim Aryoko Widodo, Yulian Ludovicus Asih Budiastuti Damayanti, Galih Sari Dhega Anindita Wibowo, Dhega Anindita Diah Adriani Malik Febriani, Sari Satya Fernandes, Albert Hidayati, Noufry Zaliva Jovina, Olivia Karami, Muhammad Zuldan Koncara, Fatan Khalif Murtono, Dwi Priyanto, Olivia Jovina Retno Indar Widayati Subagio, Devina Sugianto, Yosep Ferdinand Rahmat Triastuti, Lydia Eryana Wikanta, Edmond Rukmana Z, Mutia Dian Permatasari Mochtar Zahroh Shaluhiyah