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All Journal Majalah Kedokteran Bandung Medical Journal of Indonesia Indonesian Journal of Urology Indonesian Journal of Cancer Jurnal Aisyah : Jurnal Ilmu Kesehatan Indonesian Journal of Cancer
Ferry Safriadi
Department Of Of Urology, Faculty Of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Correlation of Age, PSA Value, Gleason Score, and Staging with Metastasis in Prostate Cancer Esfandiary, Puti Rania; Safriadi, Ferry; Mustafa, Akhmad
Majalah Kedokteran Bandung Vol 48, No 1 (2026)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v58.4225

Abstract

Prostate cancer is the fifth most common cancer among men in Indonesia and carries a substantial risk of metastasis. However, data on prognostic factors such as age, prostate-specific antigen (PSA) value, Gleason score, and local stage among Indonesian patients are still limited. This retrospective cross-sectional study analyzed medical records of prostate cancer patients treated at Dr. Hasan Sadikin General Hospital, Bandung, between 2019–2022. Independent variables were age, PSA value, Gleason score, and local stage; the dependent variable was metastatic status. Data were analyzed using chi-square and multivariate logistic regression tests. A total of 81 patients were included, of whom 44 (54.3%) had metastases. Bivariate analysis showed significant associations of PSA value, Gleason score, and local stage with metastasis (p<0.05). In multivariate analysis, only Gleason score and local stage remained significant independent predictors (p<0.05). The findings indicate that Gleason score and local tumor stage are reliable predictors of metastasis in prostate cancer, while age and PSA are not independent predictors in this cohort. Gleason score and local stage should be prioritized for risk assessment in prostate cancer management in Indonesian hospitals.
Co-Authors Aaron T Sihombing, Aaron T Aaron Tigor Sihombing Abu Surur, Abu Agus Rizal Ardy Hariandy Hamid, Agus Rizal Ardy Hariandy Ahlan Syahreza Aidil Rahman Novesar Akhmad Mustafa, Akhmad Akmal Taher Ali Ridho Al Haddar Ardiansyah, Novan Asmarinah Bambang S Noegroho Bambang Sasongko Noegroho Bethy S Hernowo, Bethy S Betthy S Hernowo, Betthy S Christian Ronald K. Tanggo Daniel Simanjuntak, Daniel El Haq, Faris Esfandiary, Puti Rania Fajriani, Rosalina Fiastuti Witjaksono Galuh Richata, Galuh Harahap, Alida Roswita I Nyoman Palgunadi Ilham Bagas Setyawan Irfan Firmansyah, Irfan Isdianto Septiadi, Isdianto Ivan Mangunsong, Albert Joko Pitoyo Jupiter Sibarani Ken Ramadhan Kuncoro Adi Kuncoro Adi Laksmi, Lidya Imelda Makmuri Yusuf Muhammad Rivai Mumuh M E, Mumuh M Nanda Daniswara, Nanda Nur Rasyid Ponco Birowo Pramana, Henry Rainy Umbas Ramadhan, Muhammad Sangaji Ramdhan, Dadan Retno Asti Werdhani Ricky Adriansjah Rizki, Dhika Ari Rosadi Putra, Rosadi Rulianov Rulianov Safendra Siregar Sani, Wildan Savira, Missy Sawkar V Pramod, Sawkar V Sawkar Vijay Pramod Stein, Lambok Kevin Steven Steven Suwandi Sugandi Tansol, Christiano Tjahjodjati vera vera, vera Wahyudi, Yuvi Warli, Syah Mirsya Wendi Rachman Widi Atmoko Wistara, Sevita Sathya Zulhardi Haroen, Zulhardi