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Surgical Research Taher, Akmal
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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The Role of Melatonin in Improving Hypoxia in Malignant Tumor: A Mini-Review Kartini, Diani; Taher, Akmal; Panigoro, Sonar S.; Setiabudy, Rianto; Jusman, Sri W; Haryana, Sofia M; Abdullah, Murdani; Rustamadji, Primariadewi
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Stone recurrence among Indonesian kidney stone formers: a comprehensive analysis of genetic polymorphism, demographic, and clinical factors Atmoko, Widi; Savira, Missy; Fajriani, Rosalina; Wistara, Sevita Sathya; Asmarinah; Harahap, Alida Roswita; Witjaksono, Fiastuti; Werdhani, Retno Asti; Safriadi, Ferry; Hamid, Agus Rizal Ardy Hariandy; Birowo, Ponco; Rasyid, Nur; Taher, Akmal
Medical Journal of Indonesia Vol. 33 No. 3 (2024): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247596

Abstract

BACKGROUND The recurrence rate of kidney stone disease (KSD) can exceed 50% within 5 years. This study aimed to investigate factors associated with stone recurrence based on single nucleotide polymorphisms (SNPs) of the calcium-sensing receptor (CaSR) rs1801725 and rs1042636, demographic, and clinical profiles. METHODS We collected data on the demographic and clinical characteristics of 80 adult kidney stone formers from April 2021 to September 2022, including peripheral blood samples, morning and 24-hour urine, and 7-day water intake records. Real-time polymerase chain reaction was used to evaluate SNP. Comparisons were made between patients with recurrent and first-time stones. RESULTS 41% of 80 patients have experienced stone recurrence. Recurrent stone formers exhibited significantly higher 24-hour urine calcium excretion (p = 0.03) and lower serum calcium levels (p = 0.019) than first-time stone formers. Hypocitraturia (100%), low urine volume (78%), and hyperoxaluria (55%) were the main abnormalities of all patients. No significant differences were found in CaSR gene polymorphisms and other demographic, biochemical, or clinical parameters. CONCLUSIONS Recurrent stone formers had higher 24-hour urine calcium excretion and lower serum calcium levels. Other risk factors and CaSR polymorphisms may insignificantly affect KSD recurrence.
Hubungan antara Bersepeda dan Infertilitas Pria: Tinjauan Sistematis dari Penelitian Saat Ini: Analisis Suryoadji, Kemal Akbar; Ridwan, Alifaturrasyid Syafaatullah; Fauzi, Ahmad; Sini, Kieran Pasha Ivan; Taher, Akmal
Cermin Dunia Kedokteran Vol 52 No 5 (2025): Kardiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i5.1241

Abstract

Introduction: Cycling is a popular sport and also has various health benefits. However, cycling carries health risks, including fertility problems. This research aims to explore the association between cycling and infertility in men. Methods: This systematic review was conducted according to a PROSPERO protocol (ID: CRD42024509255) and PRISMA guidelines using the PubMed, Cochrane, and ScienceDirect databases. Keywords “(Bicycle) AND (Infertility)” are used. The risk of bias was assessed based on the Cochrane risk of bias tool for cohort studies. Results: The final two cohort studies were included with a total of 487 cyclists. Regular cycling of more than 1.5 hours/week was associated with 34% (95% CI 4-55%) lower sperm concentration compared to control. Regular cycling of more than 5 hours/week was associated with lower sperm concentration (OR 1.92, 95% CI 1.03-3.56) and lower total sperm motility (OR 2.05, 95% CI 1.19-3.56) compared to the control group. Conclusion: There is a relationship between cycling and male infertility; a decrease in sperm concentration in men who cycle at least 1.5 hours/week and lower sperm motility in men who cycle for at least 5 hours/week. The direct efect of cycling on the incidence of infertility as a consequence needs to be explored further.
Comprehensive Efforts to Accelerate Non-Communicable Disease Services in the Era of COVID-19 in Indonesia’s Suburban Area Taher, Akmal; Gondhowiardjo, Soehartati A; Bachtiar, Adang; Prasetyo, Sabarinah; Pixelyne, Irene; Huang, Ficky; Ahmad, Rima Sumayyah
ASEAN Journal of Community Engagement Vol. 6, No. 1
Publisher : UI Scholars Hub

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The COVID-19 crisis has disrupted non-communicable disease (NCD) services in primary health care, and NCD is one of the comorbidities that increase mortality in COVID-19 patients. Efforts to accelerate NCD services were carried out with the focus on two programs: the development of integrated polyclinic NCD services and the training of community health workers (CHW) at the Tanara Community Health Center (CHC) in Banten. The development of a continuous team-based service system from the Pos Pembinaan Terpadu (Posbindu)/integrated service post to NCD services at the CHC was carried out for six months to improve the quality of human resources and help provide recommendations in the implementation of NCD services. At the end of the program, there was a 26.1% increase in the number of hypertension patients receiving treatment compared with the previous year, and there was a significant increase in the level of knowledge of CHWs after training and long-term mentoring (p < 0.001). Efforts to accelerate NCD services require support from all parties, and to ensure the continuity of these efforts, periodic monitoring and evaluation are necessary.