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Peningkatan Tingkat Pengetahuan dan Sikap Remaja Tentang Kesehatan Reproduksi dengan Peer Education Heny Astutik; Isman Amin; Roni Yuliwar
Malang Journal of Midwifery (MAJORY) Vol 1 No 2 (2019): MAJORY
Publisher : Poltekkes Kemenkes Malang & IBI Ranting Pendidikan Kota Malang

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The high problem of adolescent reproductive health is caused by the lack of basic information about reproductive health in adolescents, so adolescents tend to engage in risky behavior. The study was conducted to analyze the effect of peer education on the level of knowledge and attitudes of adolescents about reproductive health. The design of this study was a quasi-experimental design with pretest-posttest group design. Data collection using interview and observation methods. The study population was all groups of adolescents in Malang City and Regency, with a sample of adolescents who were in Malang City (Kedung Kandang Health Center Area) and Malang District (Jabung Health Center Area). The sample size was 85 teenagers selected by simple random sampling. Data collection using a questionnaire. Data were processed descriptively and analyzed using a statistical t-test. The results showed that there were significant differences in pre-test and post-test in the level of adolescent knowledge (p value <0.001) and adolescent attitudes (p value <0.001). Most adolescents in the intervention group (providing counseling by peer educators) did not support free sex and early marriage (97.3%). Health education by peer educators can remind adolescents' knowledge and attitudes about reproductive health, so that it can be developed for promotive efforts for adolescents. Keywords: Peer Education, Reproductive Health, Adolescent Knowledge, Adolescent Attitudes

Potential of Quercetin in Bitter Melon (Momordica charantia L) as an Antidiabetic: In Silico Study Roni Yuliwar; I Ketut Sudiana; Kusnanto Kusnanto; Dwi Krihariyanie; Hidayat Arifin
Journal of Global Pharma Technology Volume 12 Issue 11 (2020) Nov. 2020
Publisher : Journal of Global Pharma Technology

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Purpose: The purpose of this study is to predict the in silico molecular interactions of bitter melon quercetin with GLP-1 receptors using the comparable compounds of myricetin and allosteric modulators. Methods: The in silico test was used to predict the quercetin molecular interactions by docking using the Molegro Virtual Docker computer program. The receptor used was human GLP-1, code PDB: 5VEX with allosteric modulators ligand (97V_1201 [A]). As part from predicting molecular interactions, this study also carried out the prediction of its pharmacokinetic properties (ADME) and the toxicity of quercetin and myricetin using the pkCSM online tool program. The data analysis was performed by comparing the docking bond energies between quercetin, the allosteric modulator ligands and the myricetin comparators at the target receptor. The lower the bond energy of the ligands to the target receptor, the more stable the bonds are. This can be used to predict the biological activity of the compound. Results: The in silico test results showed that the bond energy of quercetin = -70.2678 kcal/mol, myricetin = -105,298 kcal/mol and allosteric modulators = -126,992 kcal/mol. Conclusions: The above test results indicate that quercetin has antidiabetic potential by activating the GLP-1 receptor although it is lower than the myricetin and allosteric modulators. The results of the in silico test using the pkCSM online tool program showed that the quercetin compound had good pharmacokinetic properties and a low toxicity level.

Peningkatan Tingkat Pengetahuan dan Sikap Remaja Tentang Kesehatan Reproduksi dengan Peer Education Astutik, Heny; Amin, Isman; Yuliwar, Roni
Malang Journal of Midwifery (MAJORY) Vol 1 No 2 (2019): MAJORY
Publisher : Poltekkes Kemenkes Malang & IBI Ranting Pendidikan Kota Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/majory.v1i2.2201

The high problem of adolescent reproductive health is caused by the lack of basic information about reproductive health in adolescents, so adolescents tend to engage in risky behavior. The study was conducted to analyze the effect of peer education on the level of knowledge and attitudes of adolescents about reproductive health. The design of this study was a quasi-experimental design with pretest-posttest group design. Data collection using interview and observation methods. The study population was all groups of adolescents in Malang City and Regency, with a sample of adolescents who were in Malang City (Kedung Kandang Health Center Area) and Malang District (Jabung Health Center Area). The sample size was 85 teenagers selected by simple random sampling. Data collection using a questionnaire. Data were processed descriptively and analyzed using a statistical t-test. The results showed that there were significant differences in pre-test and post-test in the level of adolescent knowledge (p value <0.001) and adolescent attitudes (p value <0.001). Most adolescents in the intervention group (providing counseling by peer educators) did not support free sex and early marriage (97.3%). Health education by peer educators can remind adolescents' knowledge and attitudes about reproductive health, so that it can be developed for promotive efforts for adolescents. Keywords: Peer Education, Reproductive Health, Adolescent Knowledge, Adolescent Attitudes

GAMBARAN FAKTOR PENOLAKAN SEMENTARA PADA CALON PENDONOR LAKI-LAKI DAN PEREMPUAN DI UDD PMI KABUPATEN MALANG TAHUN 2024: OVERVIEW OF TEMPORARY BLOOD DONATION DEFERRAL FACTORS IN MALE AND FEMALE DONORS AT UDD PMI MALANG DISTRICT IN 2024 Karimah, Hania Dinda; Ariani, Nia Lukita; Yuliwar, Roni
Journal of Nursing Care and Biomolecular Vol 10 No 1 (2025): Journal of Nursing Care and Biomolecular
Publisher : STIKes Maharani Malang

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Introduction: Men and women have an equal chance of experiencing temporary blood donation deferral. This has an impact on the unavailability of blood because the blood supply for transfusion is insufficient. This study aims to determine the description of temporary blood donation deferral factors in male and female donor candidates at the PMI UDD in Malang Regency in 2024. Method: A documentary study by taking secondary data from blood donation deferral forms that experienced temporary blood donation deferral in male donor candidates totaling 2263 data and in female donor candidates totaling 2491 data at the PMI UDD in Malang Regency in January-October 2024. Result: The highest to lowest temporary blood donation deferral factors in male donor candidates, respectively, are due to high hemoglobin levels (69.6%), high blood pressure (16.4%), low hemoglobin levels (7.7%), low blood pressure (5.8%), and underweight (0.5%). For temporary blood donation deferral factors in female donor candidates, the highest to the lowest are, respectively, due to low hemoglobin levels (67.3%), low blood pressure (19.6%), high blood pressure (8.4%), underweight (3.1%), and high hemoglobin levels (1.6%). Keywords: Donor Selection, Temporary Blood Donation Deferral, Gender

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