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Peningkatan Tingkat Pengetahuan dan Sikap Remaja Tentang Kesehatan Reproduksi dengan Peer Education Heny Astutik; Isman Amin; Roni Yuliwar
Malang Journal of Midwifery (MAJORY) Vol 1 No 2 (2019): MAJORY
Publisher : Poltekkes Kemenkes Malang & IBI Ranting Pendidikan Kota Malang

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The high problem of adolescent reproductive health is caused by the lack of basic information about reproductive health in adolescents, so adolescents tend to engage in risky behavior. The study was conducted to analyze the effect of peer education on the level of knowledge and attitudes of adolescents about reproductive health. The design of this study was a quasi-experimental design with pretest-posttest group design. Data collection using interview and observation methods. The study population was all groups of adolescents in Malang City and Regency, with a sample of adolescents who were in Malang City (Kedung Kandang Health Center Area) and Malang District (Jabung Health Center Area). The sample size was 85 teenagers selected by simple random sampling. Data collection using a questionnaire. Data were processed descriptively and analyzed using a statistical t-test. The results showed that there were significant differences in pre-test and post-test in the level of adolescent knowledge (p value <0.001) and adolescent attitudes (p value <0.001). Most adolescents in the intervention group (providing counseling by peer educators) did not support free sex and early marriage (97.3%). Health education by peer educators can remind adolescents' knowledge and attitudes about reproductive health, so that it can be developed for promotive efforts for adolescents. Keywords: Peer Education, Reproductive Health, Adolescent Knowledge, Adolescent Attitudes

Potential of Quercetin in Bitter Melon (Momordica charantia L) as an Antidiabetic: In Silico Study Roni Yuliwar; I Ketut Sudiana; Kusnanto Kusnanto; Dwi Krihariyanie; Hidayat Arifin
Journal of Global Pharma Technology Volume 12 Issue 11 (2020) Nov. 2020
Publisher : Journal of Global Pharma Technology

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Purpose: The purpose of this study is to predict the in silico molecular interactions of bitter melon quercetin with GLP-1 receptors using the comparable compounds of myricetin and allosteric modulators. Methods: The in silico test was used to predict the quercetin molecular interactions by docking using the Molegro Virtual Docker computer program. The receptor used was human GLP-1, code PDB: 5VEX with allosteric modulators ligand (97V_1201 [A]). As part from predicting molecular interactions, this study also carried out the prediction of its pharmacokinetic properties (ADME) and the toxicity of quercetin and myricetin using the pkCSM online tool program. The data analysis was performed by comparing the docking bond energies between quercetin, the allosteric modulator ligands and the myricetin comparators at the target receptor. The lower the bond energy of the ligands to the target receptor, the more stable the bonds are. This can be used to predict the biological activity of the compound. Results: The in silico test results showed that the bond energy of quercetin = -70.2678 kcal/mol, myricetin = -105,298 kcal/mol and allosteric modulators = -126,992 kcal/mol. Conclusions: The above test results indicate that quercetin has antidiabetic potential by activating the GLP-1 receptor although it is lower than the myricetin and allosteric modulators. The results of the in silico test using the pkCSM online tool program showed that the quercetin compound had good pharmacokinetic properties and a low toxicity level.

Peningkatan Tingkat Pengetahuan dan Sikap Remaja Tentang Kesehatan Reproduksi dengan Peer Education Astutik, Heny; Amin, Isman; Yuliwar, Roni
Malang Journal of Midwifery (MAJORY) Vol. 1 No. 2 (2019): MAJORY
Publisher : Poltekkes Kemenkes Malang & IBI Ranting Pendidikan Kota Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/majory.v1i2.2201

The high problem of adolescent reproductive health is caused by the lack of basic information about reproductive health in adolescents, so adolescents tend to engage in risky behavior. The study was conducted to analyze the effect of peer education on the level of knowledge and attitudes of adolescents about reproductive health. The design of this study was a quasi-experimental design with pretest-posttest group design. Data collection using interview and observation methods. The study population was all groups of adolescents in Malang City and Regency, with a sample of adolescents who were in Malang City (Kedung Kandang Health Center Area) and Malang District (Jabung Health Center Area). The sample size was 85 teenagers selected by simple random sampling. Data collection using a questionnaire. Data were processed descriptively and analyzed using a statistical t-test. The results showed that there were significant differences in pre-test and post-test in the level of adolescent knowledge (p value <0.001) and adolescent attitudes (p value <0.001). Most adolescents in the intervention group (providing counseling by peer educators) did not support free sex and early marriage (97.3%). Health education by peer educators can remind adolescents' knowledge and attitudes about reproductive health, so that it can be developed for promotive efforts for adolescents. Keywords: Peer Education, Reproductive Health, Adolescent Knowledge, Adolescent Attitudes

GAMBARAN FAKTOR PENOLAKAN SEMENTARA PADA CALON PENDONOR LAKI-LAKI DAN PEREMPUAN DI UDD PMI KABUPATEN MALANG TAHUN 2024: OVERVIEW OF TEMPORARY BLOOD DONATION DEFERRAL FACTORS IN MALE AND FEMALE DONORS AT UDD PMI MALANG DISTRICT IN 2024 Karimah, Hania Dinda; Ariani, Nia Lukita; Yuliwar, Roni
Journal of Nursing Care and Biomolecular Vol 10 No 1 (2025): Journal of Nursing Care and Biomolecular
Publisher : STIKes Maharani Malang

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Introduction: Men and women have an equal chance of experiencing temporary blood donation deferral. This has an impact on the unavailability of blood because the blood supply for transfusion is insufficient. This study aims to determine the description of temporary blood donation deferral factors in male and female donor candidates at the PMI UDD in Malang Regency in 2024. Method: A documentary study by taking secondary data from blood donation deferral forms that experienced temporary blood donation deferral in male donor candidates totaling 2263 data and in female donor candidates totaling 2491 data at the PMI UDD in Malang Regency in January-October 2024. Result: The highest to lowest temporary blood donation deferral factors in male donor candidates, respectively, are due to high hemoglobin levels (69.6%), high blood pressure (16.4%), low hemoglobin levels (7.7%), low blood pressure (5.8%), and underweight (0.5%). For temporary blood donation deferral factors in female donor candidates, the highest to the lowest are, respectively, due to low hemoglobin levels (67.3%), low blood pressure (19.6%), high blood pressure (8.4%), underweight (3.1%), and high hemoglobin levels (1.6%). Keywords: Donor Selection, Temporary Blood Donation Deferral, Gender

A Case Study of Incompatible Crossmatch in Referred Cases at The Blood Donor Unit of PMI Kota Surabaya Showmi, Alin Novia; Ariani, Nia Lukita; Yuliwar, Roni; Roeswanti, Roeswanti
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 13, No 3 (2025): EDITION NOVEMBER 2025
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v13i3.7705

Incompatible crossmatching indicates a serological incompatibility between donor and recipient blood, rendering the donor blood unsuitable for transfusion due to the potential risk of post-transfusion reactions. This study aims to present a case study of incompatible crossmatches in referred cases at the Blood Donor Unit of PMI Surabaya. A descriptive qualitative method with a case study approach was employed to explore two referred cases through detailed narrative analysis. Subject I was a referral case showing incompatibility in the major crossmatch, while Subject II showed incompatibility in the major, minor, and autocontrol tests, and also tested (positive) in the Direct Coombs Test (DCT). Further testing of Subject I at the Blood Donor Unit of PMI Surabaya showed that antibody screening (positive), antibody identification (anti-M), DCT (negative), antigen typing (M antigen: neg), major crossmatch (neg), and auto control (neg). Based on these results, the recommended transfusion for Subject I was crossmatch-compatible blood. For Subject II, the further test results were antibody screening (pos), antibody identification (non-specific antibody), DCT (pos), major crossmatch 1 and 2 (2+), and auto control (4+). The transfusion recommendation for Subject II was to use blood with a major crossmatch agglutination grade lower than that of the auto control. The different cases need different treatments. In future research, information about the history of diagnosis and transfusion history is needed to explore the background of the formation of irregular antibodies.

Pengaruh Early Mobilization Terhadap Kekuatan Otot Dan Tingkat Nyeri Pada Pasien Post Operasi Orif Di RSUD Karsa Husada Batu Tyo Herfindo Putra; Marsaid, Marsaid; Astuti, Erlina Suci; Yuliwar, Roni
Jurnal Keperawatan Muhammadiyah Vol 11 No 1 (2026): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jkm.v11i1.27968

ABSTRACT Objective: The number of patients undergoing fracture surgery with Open Reduction and Internal Fixation (ORIF) continues to increase each year, accompanied by postoperative complications such as pain, decreased muscle strength, and limited mobility. Early mobilization is considered an effective intervention to prevent these complications. This study aimed to determine the effect of early mobilization on muscle strength and pain reduction in postoperative ORIF patients. Methods: This research employed a quasi-experimental design with a pre- and post-test approach. The sample consisted of 16 patients in each group, selected using the Federer formula. The intervention group received early mobilization and analgesics, while the control group received analgesics only. Muscle strength was measured using the Manual Muscle Testing (MMT) scale, and pain levels were assessed using the Numerical Rating Scale (NRS). Data were analyzed using the Wilcoxon test with a significance level of <0.05. Results: The early mobilization group showed an improvement in muscle strength to level 3 in 68.8% of patients and a significant reduction in pain, with 87.5% of patients reporting mild pain. In contrast, the control group reached only level 2 muscle strength in 87.5% of patients, and only 31.3% experienced mild pain. The p-values were 0.002 for muscle strength and 0.001 for pain level Conclusion: Early mobilization is more effective than standard care in improving muscle strength and reducing pain in postoperative ORIF patients. Failure to implement early mobilization may lead to complications such as joint stiffness, contractures, muscle weakness, and circulatory issues that increase the risk of thrombosis. It is recommended that ward nurses provide education and implement early mobilization interventions in accordance with standard operating procedures.

EFEKTIFITAS ANTARA TEKNIK RELAKSASI GENGGAM JARI DAN RELAKSASI NAFAS DALAM TERHADAP PENURUNAN INTENSITAS NYERI POST OPERASI APPENDIKTOMI DI RUANG EDELWEIS A RSUD KARSA HUSADA BATU Pramudiva Kencana Wungu, Pinggan Ratu; Yuliwar, Roni; Hamarno, Rudi; Marsaid
Jurnal Keperawatan Muhammadiyah Vol 11 No 1 (2026): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jkm.v11i1.28535

Background: Appendicitis is the most common cause of acute abdominal pain, typically managed through appendectomy. Postoperative pain is a major issue that affects patient recovery. Non-pharmacological interventions, such as finger hold relaxation and deep breathing techniques, are considered effective in reducing pain intensity. Objective: This study aimed to compare the effectiveness of these two techniques. Methods: A quasi-experimental design with a two-group pre-test and post-test approach was used, involving 30 patients at Karsa Husada Batu Regional Hospital. The analysis used is the bivariate Wilcoxon Sign Rank Test and Mann Whitney U Test. Results: The results of the study showed that the level of anxiety before CA mammary surgery patients were given progressive muscle relaxation was 9(60%) seriously anxious and before the patients were given slow deep breathing 8(53.3%) were seriously anxious. After the intervention, 2 (13.3%) patients had the criteria for Severe Anxiety and in the slow deep breathing relaxation technique group 6 (40%) had the criteria for Severe Anxiety. Conclusion: Both techniques were found to be equally effective in reducing postoperative pain following appendectomy.

Efektivitas Akupresur Titik P⁶ dan ST³⁶ serta Relaksasi Napas Dalam terhadap Postoperative Nausea and Vomiting pada Pasien Sectio Caesarea Brilliant, Fannia Zata; Yuliwar, Roni
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 1 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss1.2199

Postoperative Nausea and Vomiting (PONV) is a common complication after Sectio Caesarea (SC) that causes discomfort and slows recovery. Acupressure and deep breathing relaxation are non-pharmacological therapies to reduce PONV. The purpose of this study was to determine the effectiveness of acupressure at points P⁶ and ST³⁶ and deep breathing relaxation on reducing PONV intensity in SC patients. The research design used was a quasi-experimental with a Two Group Pre-Test and Post-Test Design. A sample of 64 research subjects was divided into two groups. PONV intensity was measured using the RINVR scale. Data analysis used Paired Sample T-Test and Independent Sample T-Test. The results showed that the average PONV before treatment in the first group was 14.44 and after 7.34 (p < 0.05). The average before treatment in the second group was 14.63 and after 9.38 (p < 0.05). There was a significant difference in effectiveness between the two groups (p < 0.05), the first group treatment was more effective in reducing PONV. In conclusion, acupressure of the P⁶ and ST³⁶ points is more effective than deep breathing relaxation in reducing the intensity of PONV in SC patients.

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