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All Journal SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Borneo Journal of Pharmacy
Hilkatul Ilmi
Universitas Airlangga
Agriculture, Biological Sciences & Forestry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Anti-inflammatory Activity of Water Extract of Luvunga sarmentosa (BI.) Kurz Stem in the Animal Models Sabar Deyulita; Hilkatul Ilmi; Hanifah Khairun Nisa; Lidya Tumewu; Aty Widyawaruyanti; Achmad Fuad Hafid
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2968

Abstract

The study was aimed to determine the anti-inflammatory activity of water extract of the Luvunga sarmentosa stem in an animal model. Twenty-five Wistar rats were divided into five groups (n=5). Group 1 was administered 0.9% normal saline (negative control), group 2 was administered 150 mg/kg diclofenac sodium (positive control), and groups 3 to 5 were administered 50, 300, and 550 mg/kg BW of L. sarmentosa extract, respectively. Carrageenan was injected subcutaneously into each rat's subplantar region of the left hind paw. The paw volume was measured using a plethysmometer. The results showed that the water extract of L. sarmentosa stem (doses of 50, 300, and 550 mg/kg BW) significantly reduced the paw edema volume from the 4th to 5th hour compared to the negative control. The percent inhibition of edema at the 5th hour is 47.45; 46.95; 50.39%. The first phase of the edema (1st and 2nd hour) was not affected by the extract. Meanwhile, diclofenac sodium decreased paw edema volume from the 1st to 5th hour with a percent inhibition of 95.90% at the 5th hour. The histopathology result is relevant to the percentage inhibition of edema. Treatment with L. sarmentosa extract showed slight improvement, destruction of epidermal tissue, hyperkeratotic skin, and subepidermal edema. Meanwhile, positive control showed no inflammatory signs with normal keratin, subepidermal, and subcutaneous layers. The water extract of L. sarmentosa stem has anti-inflammatory activity. This extract effectively reduces the paw edema volume in the late phase with decreased neutrophil infiltration.
Free Radical Scavenging and Analgesic Activities of 70% Ethanol Extract of Luvunga sarmentosa (BI.) Kurz from Central Kalimantan Utami Islamiati; Hanifah Khairun Nisa; Hilkatul Ilmi; Lidya Tumewu; Myrna Adianti; Tutik Sri Wahyuni; Aty Widyawaruyanti; Achmad Fuad Hafid
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2983

Abstract

Luvunga sarmentosa, commonly known as saluang belum, is widely used in Kalimantan to relieve pains, rheumatism, boost the immune system, and fever. The research on the free radical scavenging and analgesic effect of the L. sarmentosa stem extract has not been reported. This study aimed to evaluate the free radical scavenging and analgesic activity of the ethanol extract of L. sarmentosa. The L. sarmentosa stem was extracted using 70% ethanol and tested for free radical scavenging using the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and analgesic activity, acetic acid-induced writhing test, and hot plate test in an animal model. The results showed that the 70% ethanol extract of the L. sarmentosa had an anti-free radical scavenging and analgesic activity. The extract has weak free radical scavenging with an IC50 value of 293.45 µg/mL. Analgesic activity using the writhing test indicated that the extract significantly reduced the writhes count after oral administration in a dose-dependent manner compared to the negative control. Extract at a dose of 550 mg/kg BW can reduce the writhing test by 67.60% compared to others. In contrast, the diclofenac sodium reduced the number of writhes by 74.74%. While in a hot plate, the extract at a dose of 550 mg/kg BW produced a maximum possible analgesia (MPA) of 17.64%, lower than the MPA of diclofenac sodium (51.01%). Analgesic activity of the extract has higher inhibition on the writhing test than on the hot plate. The extract could be responsible for the peripheral mechanism by inhibiting the prostaglandin biosynthesis.
Pelatihan inovasi produk berbahan kulit buah manggis sebagai upaya peningkatan perekonomian masyarakat Desa Songgon Kabupaten Banyuwangi Suciati Suciati; Wiwied Ekasari; Andang Miatmoko; Neny Purwitasari; Fatin Fadhilah Hasib; Hilkatul Ilmi; Firman Wicaksana; Hamizah Haula
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 2 (2025): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i2.28952

Abstract

Abstrak Desa Songgon adalah salah satu desa di Kabupaten Banyuwangi yang dikembangkan sebagai desa wisata. Desa ini memiliki kekayaan alam yang melimpah terutama buah manggis sebagai komoditas unggulan. Masyarakat Desa Songgon memanfaatkan buah manggis untuk konsumsi sehari-hari dan dijual. Harga buah manggis di pasaran sangat fluktuatif terutama saat musimnya harganya sangat murah.  Permasalahan lain yang dihadapi adalah dari kulit buah manggis yang kerap kali hanya menjadi limbah rumah tangga. Oleh karena itu perlu adanya program peningkatan pengetahuan dan keterampilan terkait pengolahan kulit buah manggis menjadi berbagai produk berdaya jual serta strategi pemasarannya kepada warga Desa Songgon. Metode yang dilakukan berupa penyuluhan dan praktek pembuatan produk kepada kader PKK dan karang taruna Desa Songgon. Hasil dari kegiatan ini adalah meningkatnya pengetahuan peserta dilihat dari kenaikan nilai pre-test 54,9 menjadi 83,9 pada post-test. Peserta juga mendapatkan keterampilan dalam pembuatan teh celup dan sabun antibakteri dengan bahan dasar kulit buah manggis.  Hasil uji aktivitas antioksidan dari teh celup mangostana dan mangostana mix yang dibuat menunjukkan bahwa produk teh yang dibuat memiliki aktivitas antioksidan yang baik. Pengetahuan dan keterampilan yang diperoleh kader PKK dan Karang Taruna diharapkan dapat diimplementasikan dalam kehidupan sehari-hari. Peserta belajar bagaimana membuat produk inovatif dari buah manggis sehingga dapat diproduksi secara komersial. Dengan demikian, dalam jangka panjang diharapkan dapat meningkatkan pendapatan masyarakat Desa Songgon. Kata kunci: Desa Songgon; Banyuwangi; buah manggis; inovasi produk. Abstract Songgon Village is one of the villages in Banyuwangi Regency that is developed as a tourist village. This village is rich in natural resources, with mangosteen being one of the most valuable commodities. The people of Songgon Village use mangosteen for daily consumption and for trade. The price of mangosteen on the market is very fluctuating, especially during mangosteen season, it is very cheap. Another issue faced is the mangosteen rind often becomes household waste. The purpose of this community service is to enhance the knowledge and skills of the residents of Songgon Village regarding the processing of mangosteen rind into a variety of innovative health products as well as the marketing strategy of the product. The method used is counseling and practices for PKK cadres and youth organizations of Songgon Village. The results of this program showed that there was an increase in the knowledge of participants according to the pre-test score (54,9) to 83,9 in post-test. Participants also gain the skill in making tea and soap from mangosteen rinds. The antioxidant activity of the tea products, mangostana and mangostana mix, showed good antioxidant activity of the tea infusion. The knowledge and skill gain by participants related innovative products from mangosteen fruit can be implemented, so that they can be produced commercially. Thus, in the long term it is expected to increase the income of the Songgon Village residents. Keywords: Songgon Village; Banyuwangi; mangosteen; innovative products.
Pelatihan pembuatan pangan fungsional dari jambu merah, mengkudu dan daun kelor untuk meningkatkan kesehatan lansia di desa Pandansari. Poncokusumo, kabupaten Malang Devanus Lahardo; Hilkatul Ilmi; Suryanto Suryanto; Firmansyah Ardian Ramadhani; Agus Pratiwi; Yusuf Alif Pratama; Wiwied Ekasari; Maria Lucia Ardhani Dwi Lestari; Andang Miatmoko; Rosita Handayani; Retno Sari; Aty Widyawaruyanti
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 1 (2024): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i1.21979

Abstract

AbstrakDesa Pandansari mempunyai potensi hasil pertanian melimpah terutama mengkudu, kelor, jahe, sereh dan jambu biji. Permasalahan yang terjadi adalah hasil panen yang tidak terserap di pasaran yang akan menjadi limbah karena belum dimanfaatkan dengan baik. Pengolahan hasil pertanian menjadi pangan fungsional menjadi peluang karena dapat meningkatkan nilai tambah dan nilai manfaat dari produk tersebut untuk kesehatan terutama bagi penduduk usia lanjut. Tim dosen Fakultas Farmasi UNAIR dengan keahlian dan kompetensi keilmuan yang dimiliki memanfaatkan aneka hasil sumber daya alam itu menjadi produk yang bernilai tinggi. Kegiatan Pengabdian kepada Masyarakat (PkM) ini bertujuan untuk memberikan pegetahuan dan ketrampilan tentang manfaat hasil pertanian dan bagaiamana mengolahnya menjadi pangan fungsioanal. Tim PkM bekerjasama dengan PKK, Kader Kesehatan dan badan relawan kebakaran dan kebencanaan (BALAKARCANA). Kegiatan dilakukan Minggu, 6 Agustus 2023 di balai desa Pandansari dengan peserta 32 orang. Materi yang disampaikan adalah cara memanfaatkan sumber daya alam , cara memanfaatkan buah atau tanaman herbal yang sudah dipanen dan cara mengemas produk. Untuk praktek yang diberikan adalah beberapa produk hasil inovasi yaitu pembuatan stik daun kelor, simplisia kering mengkudu, jus jambu biji dan sirup jahe plus. Dari hasil pre dan post test, didapatkan bahwa skor rata-rata meningkat dari 63,5 menjadi 77,9. Hal tersebut menunjukkan terjadi penambahan pengetahuan saat dilakukan kegiatan pengabdian kepada masyarakat. Saat pelaksanaan peserta terlihat antusias dalam mengikuti praktik, mereka berharap pelatihan seperti ini sering dilakukan supaya semakin banyak warga yang mengetahui bahwa tanaman yang dapat dimanfaatkan terutama untuk pendukung kesehatan lansia. Kata Kunci : lansia; obat tradisional; olahan pangan; pelatihan AbstractPandansari Village has the potential for abundant agricultural products, especially noni, moringa, ginger, lemongrass and guava. The problem that occurs is that the harvest is not absorbed in the market which will become waste because it has not been utilized properly. Processing agricultural products into functional food is an opportunity because it can increase the added value and beneficial value of these products for health, especially for the elderly population. UNAIR Faculty of Pharmacy lecturer team with their expertise and scientific competence utilizes various natural resources into high-value products. This community service activity aims to provide knowledge and skills about the benefits of agricultural products and how to process them into functional food. The PkM team collaborated with PKK, Health Cadres and the fire and disaster volunteer body (BALAKARCANA). The activity was held on Sunday, August 6, 2023 at Pandansari village hall with 32 participants. The material presented was how to utilize natural resources, how to utilize harvested fruit or herbal plants and how to package products. For the practice given are some innovative products, namely the making of moringa leaf sticks, dried noni dried simplisia, guava juice and ginger plus syrup. From the pre and post test results, it was found that the average score increased from 63.5 to 77.9. This shows that there is an increase in knowledge when community service activities are carried out. During the implementation, the participants seemed enthusiastic in participating in the practice, they hoped that training like this was often carried out so that more and more residents knew that plants could be utilized, especially for supporting the health of the elderly..Keywords: elderly; traditional medicine; food processing; training
Co-Authors Achmad Fuad Hafid Agus Pratiwi Andang Miatmoko Aty Widyawaruyanti Devanus Lahardo Fatin Fadhilah Hasib Firman Wicaksana Firmansyah Ardian Ramadhani Hamizah Haula Handayani, Rosita Hanifah Khairun Nisa Lidya Tumewu Maria Lucia Ardhani Dwi Lestari Myrna Adianti Purwitasari, Neny Retno Sari Sabar Deyulita Suciati Suciati Suryanto, Suryanto Tutik Sri Wahyuni Utami Islamiati Wiwied Ekasari Yusuf Alif Pratama