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All Journal Jurnal Dinamika Pengabdian (JDP) Science and Technology Indonesia Panrita Abdi - Jurnal Pengabdian pada Masyarakat Indonesian Journal of Chemistry SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Maria Lucia Ardhani Dwi Lestari
Fakultas Farmasi Universitas Airlangga
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Investigation of Effect of Adding Hydrophobically Modified Water Soluble Polymers on the Structure and Viscosity of Anionic Vesicle Dispersion Marco Sandjaja; Maria Lucia Ardhani Dwi Lestari
Indonesian Journal of Chemistry Vol 17, No 1 (2017)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (414.857 KB) | DOI: 10.22146/ijc.23619

Abstract

This present study was conducted to investigate the effect of adding hydrophobically modified end-capped (HM) polymers with various polyethylene oxide (PEO) chain lengths on the structure and viscosity of anionic vesicles dispersion. A pronounced increase in viscosity was observed upon adding small amount of such polymers. Based on the dynamic light scattering (DLS) and small angle neutron scattering (SANS) analysis, 10 to 30 polymer molecules per vesicles can reach maximum viscosity and where polymer molecules can interconnect the vesicles without disrupting their structure. In addition, the kinetic stability of the vesicle dispersion also enhanced. From the measurement of the electrical conductivity of the dispersion, it was observed that the presence of the PEO and polypropylene oxide (PPO) group could induce the permeability of the vesicle membrane by altering their internal structure. Controlling viscosity of vesicles dispersion without changing its structure is useful for the further application of vesicles system such as in drug delivery, cosmetics and biomedical.
Improvement in vitro Dissolution Rate of Quercetin Using Cocrystallization of Quercetin-Malonic Acid Dwi Setyawan; Sukma Adhi Permata; Ahmad Zainul; Maria Lucia Ardhani Dwi Lestari
Indonesian Journal of Chemistry Vol 18, No 3 (2018)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.013 KB) | DOI: 10.22146/ijc.28511

Abstract

The aim of the study was to improve the in-vitro dissolution rate of quercetin (Qu) using cocrystallization of quercetin. Cocrystals of quercetin (Co Qu) were produced with malonic acid (Ma) as coformer at ratio 1:2 using solvent evaporation method. Cocrystals quercetin-malonic acid (Co Qu-Ma) was characterized using Differential Thermal Analysis (DTA), Powder X-Ray Diffraction (PXRD), Scanning Electron Microscope (SEM), and Fourier Transforms Infrared Spectrophotometer (FTIR) and in-vitro dissolution study. A new endothermic peak at 277.9 °C was shown from the thermogram. Diffractogram of Co Qu-Ma showed a new diffraction peak at 2θ 9.81, 12.99, and 19.80°. Microphotograph showed that Qu and Ma exhibited a columnar-shaped and a pebble-shaped crystal, respectively, and FTIR wavenumber of O-H functional group of quercetin was shifted from its original position at 3411 to 3428 cm-1 in the physical mixture (pm) of Qu-Ma and 3418 cm-1 in Co Qu-Ma, respectively. The physicochemical characterizations using DTA, PXRD, SEM and FTIR indicated that Co Qu-Ma were successfully obtained through solvent evaporation method. The in-vitro dissolution rate of Co Qu-Ma was 95.30% at 60 min. Cocrystals effectively increased dissolution rate and dissolution efficiency in comparison to the pure quercetin and physical mixture of quercetin-malonic acid.
WEBINAR UPAYA HILIRISASI PRODUK KOSMETIKA PADA SISWA SMK FARMASI DI SURABAYA Dewi Isadiartuti; Widji Soeratri; Noorma Rosita; I Gusti Ayu Adhi Aryapatni; Suko Hardjono; Tristiana Erawati; Herra Studiawan; Maria Lucia Ardhani Dwi Lestari; Virnanda Syafira Hartatiningrum
Panrita Abdi - Jurnal Pengabdian pada Masyarakat Vol. 7 No. 1 (2023): Jurnal Panrita Abdi - Januari 2023
Publisher : LP2M Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/pa.v7i1.18675

Abstract

Pharmacy Vocational High School (SMK) students are prepared to work immediately after finishing school. Students receive lessons on the basics of pharmaceutical preparation and entrepreneurship. Cosmetics are a pharmaceutical dosage form widely used by the broader community for personal hygiene, appearance improvement, and health functions. The Minister of Health of the Republic of Indonesia No. 1175/Menkes/Per/VIII/2010 concerning cosmetic production permits provides an opportunity for cosmetic products to be produced with simple technology. During the COVID-19 pandemic, which results in a heavy economic burden for the government and society, there are business opportunities for Pharmacy Vocational School students. Community service aims to increase students' knowledge and insight and encourage students in class XI and XII of the Sekesal Pharmacy Vocational School in Surabaya and Kapasari Pharmacy Vocational School in Surabaya to become entrepreneurs in the cosmetics sector. The implementation method is through a webinar that provides material covering products, formulations, stability, and licensing of cosmetic products. Participants had the opportunity to discuss the material provided, fill out evaluations in the form of pre/post-test and make E-posters about cosmetic products. The evaluation results show an increase in participants' knowledge and insight, and participants are interested in producing cosmetic preparations, which are expected to become new business fields that can improve their welfare. --- Siswa Sekolah Menengah Kejuruan (SMK) Farmasi dipersiapkan untuk segera bekerja setelah menamatkan sekolah. Siswa memperoleh pelajaran tentang dasar-dasar pembuatan sediaan farmasi dan kewirausahaan. Kosmetika merupakan salah satu bentuk sediaan farmasi yang banyak digunakan oleh masyarakat luas untuk tujuan kebersihan diri, peningkatan penampilan, dan memiliki fungsi kesehatan. Permenkes RI No 1175/Menkes/Per/VIII/2010 tentang izin produksi kosmetika memberikan peluang produk kosmetika diproduksi dengan teknologi sederhana.  Dalam  masa pandemi covid 19, yang mengakibatkan beban ekonomi berat bagi pemerintah dan masyarakat, terdapat peluang usaha bagi siswa SMK Farmasi. Pengabdian masyarakat bertujuan untuk meningkatkan pengetahuan dan wawasan siswa serta mendorong siswa  kelas XI dan XII SMK Farmasi Sekesal Surabaya dan SMK Farmasi Kapasari Surabaya untuk berwirausaha di bidang kosmetika. Metode pelaksanaan melalui webinar dengan  pemberian materi meliputi produk, formulasi, stabilitas dan perizinan produk kosmetika. Peserta mendapatkan kesempatan berdiskusi tentang materi yang diberikan,  mengerjakan pre/post test, mengisi evaluasi, dan membuat E-poster tentang produk kosmetika. Dari hasil evaluasi diketahui terdapat peningkatan pengetahuan dan wawasan peserta dan peserta tertarik untuk memproduksi sediaan kosmetika yang diharapkan dapat menjadi lahan usaha baru yang dapat meningkatkan kesejahteraannya.
Structure and Dynamics of Curcumin Encapsulated Lecithin Micelles: A Molecular Dynamics Simulation Study Lukman Hakim; Diah Mardiana; Urnik Rokhiyah; Maria Lucia Ardhani Dwi Lestari; Zubaidah Ningsih
Science and Technology Indonesia Vol. 6 No. 3 (2021): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2024.157 KB) | DOI: 10.26554/sti.2021.6.3.113-120

Abstract

Curcumin is a natural product with potential pharmaceutical applications that can be augmented by drug delivery technology such as nano emulsion. Our study focuses on microscopic structural and dynamics response of curcumin encapsulation in micellar system with lecithin as a natural surfactant under variations of composition and temperature using molecular dynamics (MD) simulations. The results highlight the self-assembly of lecithin micelle, with curcumin encapsulated inside, from initial random configurations in the absence of external field. The variation of composition shows that lecithin can aggregate into spherical and rod-like micelle with the second critical micelle concentration lies between 0.17-0.22 mol dm−3. The radial local density centering at the micelle center of mass shows that the effective radius of micelle is indeed defined by the hydrophilic groups of lecithin molecule and theencapsulated curcumin molecules are positioned closer to these hydrophilic groups than the innermost part of the micelle. The spherical micelle is shown to be thermally stable within the temperature range of 277-310 K without a perceivable change in the spherical eccentricity. The dynamics of micelle are enhanced by the temperature, but it is shown to be insensitive to the variation of lecithin-curcumin composition within the studied range. Simulation results are in agreement with the pattern obtained from experimental results based on particle size, polydispersity index, and encapsulation efficiency.
Pelatihan pembuatan pangan fungsional dari jambu merah, mengkudu dan daun kelor untuk meningkatkan kesehatan lansia di desa Pandansari. Poncokusumo, kabupaten Malang Devanus Lahardo; Hilkatul Ilmi; Suryanto Suryanto; Firmansyah Ardian Ramadhani; Agus Pratiwi; Yusuf Alif Pratama; Wiwied Ekasari; Maria Lucia Ardhani Dwi Lestari; Andang Miatmoko; Rosita Handayani; Retno Sari; Aty Widyawaruyanti
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 1 (2024): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i1.21979

Abstract

AbstrakDesa Pandansari mempunyai potensi hasil pertanian melimpah terutama mengkudu, kelor, jahe, sereh dan jambu biji. Permasalahan yang terjadi adalah hasil panen yang tidak terserap di pasaran yang akan menjadi limbah karena belum dimanfaatkan dengan baik. Pengolahan hasil pertanian menjadi pangan fungsional menjadi peluang karena dapat meningkatkan nilai tambah dan nilai manfaat dari produk tersebut untuk kesehatan terutama bagi penduduk usia lanjut. Tim dosen Fakultas Farmasi UNAIR dengan keahlian dan kompetensi keilmuan yang dimiliki memanfaatkan aneka hasil sumber daya alam itu menjadi produk yang bernilai tinggi. Kegiatan Pengabdian kepada Masyarakat (PkM) ini bertujuan untuk memberikan pegetahuan dan ketrampilan tentang manfaat hasil pertanian dan bagaiamana mengolahnya menjadi pangan fungsioanal. Tim PkM bekerjasama dengan PKK, Kader Kesehatan dan badan relawan kebakaran dan kebencanaan (BALAKARCANA). Kegiatan dilakukan Minggu, 6 Agustus 2023 di balai desa Pandansari dengan peserta 32 orang. Materi yang disampaikan adalah cara memanfaatkan sumber daya alam , cara memanfaatkan buah atau tanaman herbal yang sudah dipanen dan cara mengemas produk. Untuk praktek yang diberikan adalah beberapa produk hasil inovasi yaitu pembuatan stik daun kelor, simplisia kering mengkudu, jus jambu biji dan sirup jahe plus. Dari hasil pre dan post test, didapatkan bahwa skor rata-rata meningkat dari 63,5 menjadi 77,9. Hal tersebut menunjukkan terjadi penambahan pengetahuan saat dilakukan kegiatan pengabdian kepada masyarakat. Saat pelaksanaan peserta terlihat antusias dalam mengikuti praktik, mereka berharap pelatihan seperti ini sering dilakukan supaya semakin banyak warga yang mengetahui bahwa tanaman yang dapat dimanfaatkan terutama untuk pendukung kesehatan lansia. Kata Kunci : lansia; obat tradisional; olahan pangan; pelatihan AbstractPandansari Village has the potential for abundant agricultural products, especially noni, moringa, ginger, lemongrass and guava. The problem that occurs is that the harvest is not absorbed in the market which will become waste because it has not been utilized properly. Processing agricultural products into functional food is an opportunity because it can increase the added value and beneficial value of these products for health, especially for the elderly population. UNAIR Faculty of Pharmacy lecturer team with their expertise and scientific competence utilizes various natural resources into high-value products. This community service activity aims to provide knowledge and skills about the benefits of agricultural products and how to process them into functional food. The PkM team collaborated with PKK, Health Cadres and the fire and disaster volunteer body (BALAKARCANA). The activity was held on Sunday, August 6, 2023 at Pandansari village hall with 32 participants. The material presented was how to utilize natural resources, how to utilize harvested fruit or herbal plants and how to package products. For the practice given are some innovative products, namely the making of moringa leaf sticks, dried noni dried simplisia, guava juice and ginger plus syrup. From the pre and post test results, it was found that the average score increased from 63.5 to 77.9. This shows that there is an increase in knowledge when community service activities are carried out. During the implementation, the participants seemed enthusiastic in participating in the practice, they hoped that training like this was often carried out so that more and more residents knew that plants could be utilized, especially for supporting the health of the elderly..Keywords: elderly; traditional medicine; food processing; training
PENDIDIKAN POLA HIDUP SEHAT PASCA PANDEMI COVID-19 SEBAGAI UPAYA MENJAGA KESEHATAN SISWA SMP DI MAGETAN Isadiartuti, Dewi; Sari, Retno; Diyah, Nuzul Wahyuning; Lestari, Maria Lucia Ardhani Dwi; Rudyanto, Marcellino; Kusumawati, Idha; Setyawan, Dwi; Rohana, Melissa; Dewanthy, Kyrana Sekar; Fauzia, Alfi Nur; Siammita, Dhea Anansya
Jurnal Dinamika Pengabdian Vol. 10 No. 1 (2024): JURNAL DINAMIKA PENGABDIAN VOL. 10 NO. 1 OKTOBER 2024
Publisher : Departemen Budidaya Pertanian Fakultas Pertanian UNHAS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jdp.v10i1.32996

Abstract

Pembelajaran tatap muka secara offline bagi pelajar sudah dimulai kembali setelah pandemi Covid-19 melanda Indonesia. Sejak pandemi ditetapkan WHO tanggal 11 Maret 2020, telah menyebabkan 5.956.561 orang terkonfirmasi positif dan sebanyak 153.599 orang meninggal dunia (per 21 Maret 2022) di Indonesia. Kembalinya proses belajar mengajar ke kondisi normal perlu diantisipasi dengan kesadaran dan tanggung jawab siswa terhadap protokol kesehatan yang dianjurkan pemerintah. Tujuan kegiatan ini adalah untuk meningkatkan pemahaman dan kesadaran siswa SMPN tentang pola hidup sehat dalam upaya menjaga kesehatan pasca pandemi Covid-19. Dalam program ini siswa didorong untuk menerapkan pola hidup sehat diantaranya dengan senantiasa menjaga kebersihan tangan dan menjaga daya tahan tubuh. Pengabdian masyarakat dilakukan dalam bentuk webinar dengan platform zoom diikuti oleh 59 siswa dari SMPN 1 Magetan dan diberikan dalam bentuk pre-test dan post-test, ceramah, diskusi dan pembuatan e-poster. Hasil kuesioner yang diberikan kepada peserta sebelum kegiatan diketahui 100% siswa telah mendapatkan vaksinasi dosis dua, 100 % siswa setuju proses pembelajaran pasca pandemi dilakukan secara luring, 100% siswa setuju mengikuti protokol kesehatan selama mengikuti kegiatan pembelajaran di sekolah, 73,58% siswa selalu menggunakan masker, 35,85% siswa mencuci tangan sebelum masuk sekolah, 41,51% siswa menjaga jarak dengan temannya, dan 1,89% siswa menderita penyakit infeksi Covid-19 selama proses pembelajaran luring pasca pandemi. Hasil evaluasi kegiatan berupa pre-test dan post test serta pembuatan e-poster diketahui terdapat peningkatan pemahaman siswa terhadap materi yang disampaikan dan semua peserta menyatakan setuju materi pola hidup sehat yang disampaikan dapat diaplikasikan dalam mengikuti proses pembelajaran di sekolah. ABSTRACT Offline face-to-face learning for students has started again after the Covid-19 pandemic hit Indonesia. Since the pandemic was declared by WHO on March 11 2020, it has resulted in 5,956,561 people being confirmed positive and 153,599 people dying (as of March 21 2022) in Indonesia. The return of the teaching and learning process to normal conditions needs to be anticipated with students' awareness and responsibility for the health protocols recommended by the government. The aim of this activity is to increase understanding and awareness of junior high school students about healthy lifestyles in an effort to maintain health after the Covid-19 pandemic. In this program, students are encouraged to adopt a healthy lifestyle, including always keeping their hands clean and maintaining their immune system. Community service was carried out in the form of a webinar with a zoom platform attended by 59 students from SMPN 1 Magetan and given in the form of pre-test and post-tests, lectures, discussions and making e-posters. The results of the questionnaire given to participants before the activity showed that 100% of students had received the second dose of vaccination, 100% of students agreed that the post-pandemic learning process would be carried out offline, 100% of students agreed to follow health protocols while participating in learning activities at school, 73.58% of students always wearing masks, 35.85% of students washing their hands before entering school, 41.51% of students keeping their distance from their friends, and 1.89% of students suffering from Covid-19 infection during the post-pandemic offline learning process. The results of the evaluation of activities in the form of pre-test and post-tests and making e-posters showed that there was an increase in students' understanding of the material presented and all participants agreed that the healthy lifestyle material presented could be applied in following the learning process at school. Keywords: Healthy lifestyle, Covid-19, post-pandemic, student education, maintaining health.
Studies on the Loading and Release of Metformin HCl Using Hydrogels with EGDMA and MBA as Crosslinkers Ariyaldi, Ariyaldi; Nizardo, Noverra Mardhatillah; Lestari, Maria Lucia Ardhani Dwi
Indonesian Journal of Chemistry Vol 25, No 1 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.95826

Abstract

Hydrogel poly(N-vinylcaprolactam-co-2-(dimethylamino)ethylmethacrylate) or (P(NVCL-co-DMAEMA)) containing the active drug metformin HCl were synthesized using the free radical polymerization method in the presence of DMAEMA and NVCL monomers by using two different crosslinkers: ethylene glycol dimethacrylate (EGDMA) and methylene bisacrylamide (MBA). FTIR spectra confirmed the successful formation of hydrogel and its loading with metformin HCl. SEM analysis revealed the physical shape and surface features. Regarding physical appearance, the texture of the hydrogel is sticky and elastic. When the hydrogel was immersed in a solution, it swelled, and returned to its original shape after drying. Additionally, the chemical degradation temperature is thermally stable at 329.75 °C. The loading test results showed that the active drug in EGDMA was 18.38 (% w/w) and 26.19 (% w/w) in MBA as crosslinkers, loaded within 24 h. The drug-loaded hydrogel containing EGDMA as crosslinkers in pH 7.4 had the highest drug release in 24 h compared to MBA. Then, the drug released from hydrogel with EGDMA in pH 2 had the highest drug release than MBA within 30 min. The P(NVCL-co-DMAEMA) hydrogel has the potential for a drug delivery system. However, additional optimizations are necessary to improve the efficiency of the hydrogels as a carrier.
Edukasi Pemanfaatan Obat Tradisional, Aromaterapi, dan Akupresur untuk Mengurangi Kelelahan pada Tenaga Kesehatan dan Pasien di Rumah Sakit Universitas Airlangga: Educational Intervention on the Use of Traditional Medicine, Aromatherapy, and Acupressure to Reduce Fatigue Among Healthcare Workers and Patients at Airlangga University Hospital Handayani, Rosita; Sukardiman, Sukardiman; Widyowati, Rr. Retno; Imandiri, Ario; Ekasari, Wiwied; Sudjarwo, Sudjarwo; Hafid, Achmad Fuad; Wahyuni, Tutik Sri; Lestari, Maria Lucia Ardhani Dwi; Sulistyowaty, Melanny Ika
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 8 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i8.10041

Abstract

Excessive fatigue and burnout are serious issues frequently experienced by healthcare workers and patients with chronic illnesses, particularly within high-pressure healthcare environments. These conditions not only impair the performance of medical personnel but also negatively affect the therapeutic outcomes of patients. To address this problem, a community service activity was conducted through educational outreach on fatigue and burnout management, utilizing acupressure, traditional remedies, and aromatherapy. The program involved 49 participants, including healthcare workers and Surabaya's chronic disease patients. Held on September 11, 2024, the activity employed lectures and two-way discussions as its primary methods. The material covered included traditional medicine, basic acupressure techniques, and training in roll-on and massage oil aromatherapy preparation. A structured module was developed to enhance learning effectiveness, and participants' comprehension was evaluated through pre- and post-tests. Statistical analysis using a paired t-test revealed a significant improvement in participants' understanding (p <0.01), with an average score increase of 19.8%. This initiative demonstrates that practical and interactive education can effectively improve participants' knowledge and skills in managing fatigue and burnout. Therefore, the outcomes of this activity are essential as a promotive and preventive effort to support the physical and mental well-being of vulnerable groups in healthcare settings.
Co-Authors Achmad Fuad Hafid Agus Pratiwi Ahmad Zainul Andang Miatmoko Ario Imandiri, Ario Ariyaldi, Ariyaldi Aty Widyawaruyanti Devanus Lahardo Dewanthy, Kyrana Sekar Dewi Isadiartuti Diah Mardiana Diyah, Nuzul Wahyuning Dwi Setyawan Fauzia, Alfi Nur Firmansyah Ardian Ramadhani Handayani, Rosita Herra Studiawan Hilkatul Ilmi I Gusti Ayu Adhi Aryapatni Idha Kusumawati Lukman Hakim Marcellino Rudyanto Marco Sandjaja Melanny Ika Sulistyowaty Noorma Rosita Noverra Mardhatillah Nizardo Retno Sari Retno Sari Rohana, Melissa Siammita, Dhea Anansya Sudjarwo Sudjarwo Sukardiman Sukma Adhi Permata Suko Hardjono Suryanto, Suryanto Tristiana Erawati Tutik Sri Wahyuni Urnik Rokhiyah Virnanda Syafira Hartatiningrum Widji Soeratri Widyowati, Rr. Retno Wiwied Ekasari Yusuf Alif Pratama Zubaidah Ningsih