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All Journal Dentika Dental Journal Journal of Dentistry Indonesia Padjadjaran Journal of Dentistry
Elizabeth Fitriana Sari
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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EFEK EKSTRAK ALOE VERA TERHADAP CANDIDA ALBICANS YANG DIISOLASI DARI RONGGA MULUT PENDERITA HIV/AIDS DENGAN TEKNIK TUBE DILUTION : EFFECT OF ALOE VERA LEAF EXTRACT TO CANDIDA ALBICANS ISOLATED FROM ORAL CAVITY OF HIV/AIDS PATIENTS BY TUBE DILUTION TECHNIQUE Elizabeth Fitriana Sari; Gus Permana Subitha
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.249 KB) | DOI: 10.32734/dentika.v16i2.1822

Abstract

Oral candidiasis is the third major opportunistic infection in people with HIV/AIDS. The antifungal has a very important role to prevent candidemia. But the use of antifungal has developed resistancy, for this reason it is important to find other high potent and cost effective antifungal. In this study Aloe vera was choosen because of its beneficial properties which has already been proven scientifically. The objective of the study was to investigate antifungal effect by finding the minimal inhibitory concentrations (MICs) and minimal fungicidal concentrations (MFCs) of Aloe vera leaf to Candida albicans isolated from oral cavity of HIV/AIDS patients, and to Candida albicans ATCC 10231 strain as the control group. Ethanol was used for the extraction of the leaf after obtaining the gel from it. MICs and MFCs were tested by tube dilution technique. Eight identified samples of Candida albicans isolated from oral cavity of HIV/AIDS patients. The result showed that from 3 samples had MIC 25%, and 4 samples 50%. MFC showed 1 sample in 12.5%, 3 samples in 100%, but 4 samples could still grow in 100% concentration with different number of colony forming units. As the control group, Candida albicans ATCC 10231 showed MIC in 25% and MFC in 75%. In conclusion, aloe vera plants seem to have promising role to cure oral candidiasis in HIV/AIDS patients because of its antifungal and immunomodulatory properties.
The antibacterial effect of β-pinene derived from Citrus aurantifolia peel against oral Streptococcus mutans ATCC 25175 Julaeha, Euis; Herlina, Tati; Nurzaman, Mohamad; Mayanti, Tri; Kurnia, Dikdik; Sari, Elizabeth Fitriana
Padjadjaran Journal of Dentistry Vol 33, No 1 (2021): March 2021
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol33no1.29200

Abstract

Introduction: Streptococcus mutans has been known to play a major role in dental caries development. This tooth decay is the most common oral disease affecting people in the world. Hence, discovering the new herbal antibacterial agent seems to become more promising yet challenging. One of natural antibacterial source is the peel of Citrus aurantifolia, as it may contain antibacterial active compounds against pathogenic oral microbes. This study was aimed to isolate antibacterial compound from essential oil of Citrus aurantifolia and to analyse its antibacterial activity against oral Streptococcus mutans ATCC 25175. Methods: Type of research was laboratory experimental. The essential oil was isolated from peel of Citrus aurantifolia by hydro-distillation technique and further isolation of antibacterial compounds was conducted by combination column chromatography using organic solvent, and the structure was determined by UV-Vis, infrared (IR), 1D NMR of 1H-, 13C-NMR and DEPT 135° in CDCl3 spectrometers methods. The antibacterial activity was tested against Streptococcus mutans ATCC 25175 using the Kirby-Bauer method. Results: 0.75% yield was obtained from the essential oil of peel Citrus aurantifolia and after purification, an antibacterial compound was identified as β-pinene with the molecular formula C10H16. Furthermore, the β-pinene from peel of Citrus aurantifolia exerted inhibition growth against Streptococcus mutans at concentration of 2000, 1000, and 500 ppm by showing respectively, inhibition values of 13.0, 11.9, and 11.6 mm on paper disk. Conclusion: In the present study, the essential oil of Citrus aurantifolia peel is proven to contain prospective antibacterial compound (β-pinene) that potentially can be used as natural antibacterial alternative choice to manage oral disease associated with Streptococcus mutans infection.
Perception of Conventional Cigarettes and Vaping among Smokers and Nonsmokers: A Cross-sectional Study Gunardi, Indrayadi; Amtha, Rahmi; Hartanto, Firstine Kelsi; Falatehan, Niko; Heriandi, Alyah; Kurniawan, Angelita Victoria; Nadiah, Najla; Poedjiastoeti, Wiwiek; Andrijanto, Andrijanto; Sari, Elizabeth Fitriana
Journal of Dentistry Indonesia
Publisher : UI Scholars Hub

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Abstract

Objectives: The growing popularity of vaping has introduced additional challenges, as potential health risks are still under investigation. Exploring differences in smoking perceptions between smokers and non-smokers could provide valuable insights into smoking behavior and inform effective intervention strategies. This study aimed to evaluate and compare the perceptions of smoking, specifically vaping and conventional cigarette use, among young adult smokers and non-smokers. Methods: An analytical cross-sectional design was employed, with 542 university students included through random sampling, using a questionnaire consisting of 8 items. Data were analyzed using the Kruskal-Wallis test and Rasch model analysis. Results: Of the subjects, 259 (48%) used vapes and 283 (52%) were non-smokers. The age distribution was as follows: under 19 years (13.51% vs 38.87%), 19-20 years (46.33% vs 32.16%), and over 21 years (40.15% vs 28.98%). The Wright map indicated perceptual differences between smokers and non-smokers, with smokers showing greater agreement with smoking perceptions (>1 logit). Significant differences (p < 0.001) were found in each item across all groups. Conclusion: The study identified distinct perceptual differences regarding smoking between smokers and non-smokers, with smokers having a more favorable perception towards smoking. Non-smokers generally showed a stronger aversion to conventional cigarettes compared to electronic ones. These findings underscore the importance of developing targeted smoking cessation programs that address the specific perceptions and attitudes of both groups.
Co-Authors Andrijanto Andrijanto, Andrijanto Dikdik Kurnia Euis Julaeha Gus Permana Subitha Gus Permana Subitha Hartanto, Firstine Kelsi Heriandi, Alyah Indrayadi Gunardi, Indrayadi Kurniawan, Angelita Victoria Mohamad Nurzaman Nadiah, Najla Niko Falatehan Rahmi Amtha Tati Herlina Tri Mayanti Wiwiek Poedjiastoeti, Wiwiek