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IMMOBILISASI MIKROKAPSUL MINYAK JERUK NIPIS (Citrus aurantifolia) PADA KAIN KAPAS Wahyudi, Tatang; Mulyawan, Agus Surya; Sugiyana, Doni; Julaeha, Euis
Arena Tekstil Vol 32, No 2 (2017)
Publisher : Arena Tekstil

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.674 KB)

Abstract

Pada penelitian ini telah dipelajari sintesis mikrokapsul minyak jeruk nipis (Citrus aurantifolia) dan immobilisasinya pada sampel kain kapas. Sintesis mikrokapsul dilakukan dengan metode polimerisasi in-situ menggunakan bahan kulit (shell) melamin formaldehid. Immobilisasi mikrokapsul pada kain kapas dilakukan dengan metode pad-dry dengan menggunakan binderpoliakrilat dan crosslinking agent N-methylol dihydroxyethylene urea. Sebagai bahan pembanding,metode immobilisasi yang sama dilakukan pula pada mikrokapsul minyak jeruk nipis berbasis kulit etil selulosa. Hasil penelitian menunjukkan bahwa mikrokapsul hasil sintesis terkarakterisasi mempunyai bentuk sperik dengan ukuran partikel 0,44 – 2,10 μm. Immobilisasi mikrokapsul berbasis melamin formaldehid memperlihatkan hasil optimum menggunakan binder poliakrilat, sedangkan mikrokapsul berbasis etilselulosa memperlihatkan hasil optimummenggunakan crosslinking agent N-methylol dihydroxyethylene urea.Kedua sampel kain dengan teknik immobilisasi optimummemperlihatkan ketahanan terhadap pencucian cukup baik hingga setara 5 kali pencucian rumah tangga.
SENYAWA STEROID DARI KULIT BATANG Dysoxylum alliaceum DAN AKTIVITASNYA TERHADAP SEL KANKER PAYUDARA MCF-7 Nurcahyanti, Ois; Julaeha, Euis; Mayanti, Tri
Chimica et Natura Acta Vol 3, No 2 (2015)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.197 KB) | DOI: 10.24198/cna.v3.n2.9184

Abstract

Dysoxylum merupakan salah satu genus yang memiliki metabolit sekunder dan aktivitas yang beragam, salah satu aktivitas yang menarik adalah mampu bertindak sebagai agen P-gp pada sel kanker payudara MCF-7. Kulit batang D.alliaceum dimaserasi berturut–turut dengan n-heksana, etil asetat dan metanol. Ekstrak n-heksan dipisahkan dan dimurnikan dengan berbagai teknik kromatografi dipandu dengan analisis kromatografi lapis tipis diperoleh dua senyawa stigmast-5-en-3β-ol (1), stigmasterol (2). Struktur kimia senyawa tersebut telah ditetapkan berdasarkan intrepretasi data-data spektroskopi dan dibandingkan dengan data spektra dari penelitian sebelumnya. Semua isolat senyawa dievaluasi aktivitas sitotoksiknya terhadap sel kanker payudara MCF-7. Senyawa 1 dan 2 dirujuk dari literatur menunjukkan aktivitas kuat dengan IC50 8,65 μg/mL.
SENYAWA HASIL ISOLASI DARI TUMBUHAN KI ENCOK (Plumbago Zeylanica) YANG BERAKTIVITAS ANTIBAKTERI PENYAKIT MULUT DAN GIGI Julaeha, Euis; Herlina, Tati; Mayanti, Tri; Wibisono, Aditya Seiza; Yulisar, Riza; Diantini, Ajeng
Chimica et Natura Acta Vol 2, No 2 (2014)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.711 KB) | DOI: 10.24198/cna.v2.n2.9158

Abstract

Plumbago zeylanica (Ki Encok) merupakan salah satu tumbuhan obat multifungsi yang banyak ditemukan di Indonesia. Daun dan akarnya berkhasiat sebagai obat pada berbagai penyakit termasuk anti jamur dan anti bakteri. Penelitian ini dilakukan untuk mengetahui senyawa bioaktif antibakteri yang dapat digunakan untuk mengobati penyakit gigi dan mulut. Dari hasil pemisahan dan pemurnann fraksi aktif, tiga senyawa telah berhasil diisolasi dari ekstrak n-heksana dan etilasetat daun Ki Encok (Plumbago zeylamica), yaitu 3β-galaktosasitosterol (1), epi-isoshinanolon (2), dan metil 2,4-dihidroksibenzoat (3). Ketiga senyawa tersebut telah diuji aktivitasnya terhadap bakteri untuk penyakit mulut dan gigi yaitu Streptococcus mutan dan Streptococcus sanguinis. Hasilnya, diameter zona hambat dari senyawa 1, 2, dan 3 terhadap bakteri S. Sanguinis berturut-turut sebesar 12,0; 10,3; dan 12,0 mm, sedangkan terhadap bakteri S. Mutans berturut-turut sebesar 13,3; 11,7; dan 13,5 mm.
IDENTIFIKASI POPULASI BAKTERI DALAM SPONS PENCUCI PIRING DENGAN METODE PCR-RFLP Gaffar, Shabarni; Maksum, Iman Permana; Julaeha, Euis
Chimica et Natura Acta Vol 2, No 2 (2014)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (293.895 KB) | DOI: 10.24198/cna.v2.n2.9154

Abstract

Spons pencuci piring 200.000 kali lebih kotor dibanding dudukan toilet. Berbagai bakteri penyebab penyakit seperti Eschericia coli, Pseudomonas dan Staphylococcus, berkembang biak di permukaan yang basah. Selain itu, 500 ribu bakteri hidup di dalam saluran pembuangan bak cuci piring. Jika spons dalam kondisi tidak kering (lembab karena direndam), maka akan menjadi markas semua bakteri. Penelitian ini bertujuan untuk menentukan populasi bakteri yang terdapat pada spons cuci piring yang basah. Identifikasi dilakukan dengan metoda molekular berbasis DNA yaitu teknik PCR-RFLP gen 16s rDNA. Metoda PCR-RFLP merupakan genetik fingerprinting yang akurat, cepat dan sederhana. Koloni bakteri yang ditumbuhkan dari spons pencuci piring di lisis dan digunakan sebagai templat untuk PCR. Hasil PCR gen 16s rDNA yang berukuran 1400 pb, dipotong dengan enzim restriksi, Hinf1. Hasil penelitian menunjukkan terdapat empat pola pemotongan yang berbeda-beda. Pola yang berbeda ini menunjukkan terdapat empat populasi yang berbeda hidup pada spons basah. Kami mengidentifikasi bahwa salah satu mikroba yang tumbuh adalah E. coli yang merupakan bakteri patogen.
Antioxidant Activity of Non-Volatile Lime (Citrus aurantifolia Swingle) Extract Permadi, Nandang; Julaeha, Euis; Rosandi, Yudi; Nurzaman, Mohamad
Jurnal Agrinika: Jurnal Agroteknologi dan Agribisnis Vol 5, No 2 (2021): SEPTEMBER
Publisher : Kadiri University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/agrinika.v5i2.1919

Abstract

The paper reports the antioxidant activity of a non-volatile fraction of lime processing byproducts from the lime syrup home industry. The activity was measured by spectrophotometry to obtain the 50% inhibition concentration (IC50) using the 2,2- diphenyl-1-picrylhydrazyl (DPPH) method. The sample was extracted by the maceration method with n-hexane, ethyl-acetate, and ethyl-ethanol. The IC50 values of 681 ppm, 458 ppm, and 2,775 ppm were n-hexane, ethyl-acetate, and ethyl-ethanol. The experiments concluded that the ethyl-acetate extract provides the best inhibition value to scavenge free-radicals DPPH. The HPLC and mass spectroscopy were measured to find out the content and group of active compounds. The significant compounds consisted of naringin, poncirin, or neoponcirin, which are known as antioxidant substances. The result shows the potential application of the lime by-products, its volatile fraction, and the nonvolatile fraction, which is the production residue of lime peel. This work can be applied as an alternative to zero-waste lime production, which may benefit the industry and the environment.
Stigmast-5(6)-en-3(6)-ol dari Herba Tumbuhan Krokot (Lygodium microphyllum) Hadi Kuncoro; Kindi Farabi; Euis Julaeha; Laode Rijai; Unang Supratman
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 1, No. 1, Mei 2015
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (565.678 KB) | DOI: 10.15408/jkv.v0i0.3152

Abstract

A steroid, stigma-5(6)-en-3β-ol or β-sitosterol (1) had been isolated from a n-hexane extract of the Krokot plant herb (Lygodium microphyllum). The chemical structure of 1 was identified on the basis of spectroscopic evidences and by comparison with those of spectra data previously reported. The investigation of steroid, stigma-5(6)-en-3β-ol was from L. microphyllum plant was reported inthis research for first time.DOI :http://dx.doi.org/10.15408/jkv.v0i0.3152
FLAVONOLS FROM THE LEAVES Lygodium microphyllum (Lygodiaceae) Hadi Kuncoro; Kindi Farabi; Euis Julaeha; Laode Rijai; Yoshihito Shiono; Unang Supratman
Jurnal Kimia (Journal of Chemistry) Vol. 11. No. 1 Januari 2017
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (256.797 KB) | DOI: 10.24843/JCHEM.2017.v11.i01.p02

Abstract

Flavonol compounds, quercetin (1) and quercetin-3-O-?-D-glucopyranoside (2) have been isolated from the ethyl acetate extract of Lygodium microphyllum leaves. The chemical structures of flavonol compounds were identified based on spectroscopic data and by comparison of spectral data obtained previously. The discovery of flavonol compounds in Lygodium microphyllum was shown in this study for the first time.
Flavonoid Compounds from the Herb of Krokot (Lygodium microphyllum) and their antioxidant activity against DPPH Hadi Kuncoro; Kindi Farabi; Laode Rijai; Euis Julaeha; Unang Supratman; Yoshihito Shiono
Journal of Mathematical and Fundamental Sciences Vol. 50 No. 2 (2018)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2018.50.2.7

Abstract

Six flavonoid compounds, kaempferol (1), quercetin (2), acacetin (3), quercetin-3-O-β-D-glucopyranoside (4), kaempferol-3-O-β-D-glucopyranoside (5), and isorhamnetin-3-O-β-D-glucopyranoside (6), were isolated from the methanol extract of the Lygodium microphyllum herb. The chemical structures of compounds 1-6 were identified on the basis of spectroscopic evidence and comparison with previously reported spectral data. Compounds 1-6 were isolated for first time from this plant. Their antioxidant activity against DPPH (2,2-Diphenyl-1-picrylhydrazyl) was evaluated. Among the compounds, quercetin (2) showed high antioxidant activity with IC50 values of 6.94 ± 0.03 μg/mL.
A Known Naphthalene, Isoeleutherol, from the Herb of Lygodium microphyllum Kuncoro, Hadi; Farabi, Kindi; Rijai, Laode; Julaeha, Euis; Shiono, Yoshihito; Supratman, Unang
Makara Journal of Science Vol. 22, No. 4
Publisher : UI Scholars Hub

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Abstract

A known naphthalene, isoeleutherol (1), was isolated from the herb ofLygodium microphyllum. The chemical structure of 1 was determined on the basis of spectroscopic data mainly UV, IR, HRTOFMS, 1D-and 2D-NMR spectroscopy, aswell as by comparing with compounds previously reported. Isoeleutherol was isolated from this plant for the first timeand showed moderate antioxidant activity against DPPH (2,2-diphenyl-1-picrylhydrazyl) with IC50 value of 53.96 ± 2.87 μg/mL.
Hubungan Pengetahuan, Peran Keluarga Dan Kepemilikan Jaminan Kesehatan Dengan Pemilihan Penolong Persalinan Pada Ibu Hamil Di Desa Batuhideung Kecamatan Cimanggu Pandeglang Banten Tahun 2022: Relationship Between Knowledge, Family Role, and Ownership of Health Insurance with the Selection of Birth Assistance for Pregnant Women in Batuhideung Village, Cimanggu Pandeglang District, Banten in 2022 Julaeha, Euis
Indonesian Scholar Journal of Nursing and Midwifery Science Vol. 2 No. 09 (2023): Vol. 2 No. 09 (2023): Vol. 2 No. 09 (2023): Indonesian Scholar Journal of Nurs
Publisher : Dohara POAJ

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54402/isjnms.v2i09.345

Abstract

Introduction: The selection of birth attendants is one of the reproductive rights of individuals in determining where to give birth and who will assist in childbirth. Many factors influence the selection of birth attendants, including maternal knowledge, family roles, and BPJS card ownership. In the Cimanggu Health Center in 2021 48,7% of mothers were assisted by midwives, while 50,3% of mothers who gave birth were assisted by traditional birth attendants. The purpose of the study was to determine the relationship between knowledge, family roles, and health insurance ownership with the selection of birth attendants for pregnant women in Batuhideung Village, Cimanggu District, Pandeglang Banten in 2022.  Methods: The research method used was quantitative analysis using a cross-sectional approach using primary data, the number of samples was as much as 52 third-trimester pregnant women, total sampling technique, data analysis using Chi-Square test.    Result: The results of the univariate analysis revealed that the selection of birth attendants for pregnant women was mostly by health workers (midwives) 63,5%; with good knowledge of 55,8%; the role of the family supporting 71,2% and the ownership of BPJS Health was 65,4%. Based on the results of the chi-square test, there was a significant relationship between knowledge (p = 0,000); family roles (p = 0,011); and BPJS Health ownership (p = 0,000) with the selection of birth attendants for pregnant women.  Discussion: The conclusion of the study there is a significant relationship between knowledge, family roles, and ownership of BPJS Health with the selection of birth attendants for pregnant women. It is hoped that mothers and families can provide mutual support in choosing delivery assistance assisted by health workers, besides having a BPJS card so that mothers and families feel calm during childbirth because they get cost waivers.