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All Journal AL KAUNIYAH Scientiae Educatia: Jurnal Pendidikan Sains Journal Syifa Sciences and Clinical Research (JSSCR) JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Indonesian Journal of Pharmaceutical Education Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya Jurnal Pengabdian Masyarakat: BAKTI KITA Jurnal Pengabdian Harapan Ibu (JPHI) Jurnal Pharma Bhakta Scientiae Educatia: Jurnal Pendidikan Sains
Nurul Istiqomah
Institut Ilmu Kesehatan Bhakti Wiyata Kediri
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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EFEKTIVITAS ANALGESIK EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) TERHADAP MENCIT (Mus musculus) Erni Anikasari; Nurul Istiqomah; Mita Amalia
JURNAL PHARMA BHAKTA Vol 2 No 1 (2022): Juni 2022
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Analgesik adalah suatu senyawa yang berkhasiat untuk menekan rasa nyeri. Analgesik memiliki efek samping apabila dikonsumsi dengan dosis berlebih antara lain reaksi hipersensitivitas, gangguan pada usus dan lambung, kerusakan ginjal, serta dapat menyebabkan kerusakan pada hati. Latar Belakang: Secara umum penggunaan obat tradisional dinilai lebih aman dibandingkan obat modern, hal tersebut disebabkan oleh obat tradisional memiliki efek samping rendah jika digunakan secara tepat. Salah satu tanaman obat yang dimanfaatkan untuk pengobatan tradisional yaitu kersen (Muntingia calabura L.). Berdasarkan penelitian sebelumnya dinyatakan bahwa ekstrak etanol daun kersen memiliki efek analgesik. Tujuan: Mengetahui dosis efektif dari ekstrak daun kersen yang dapat digunakan sebagai analgesik. Metode: Pengujian dilakukan secara in vivo mengunakan 12 ekor mencit jantan (Mus musculus) dengan 4 perlakuan. Kelompok kontrol negatif menggunakan Cmc-Na 1%, kelompok kontrol positif menggunakan asam mefenamat 500 mg/kgBB, kelompok perlakuan Ekstrak Etanol Daun Kersen dengan dosis 300 mg/kgBB dan 600 mg/kgBB. Analisis data menggunakan SPSS one way anova. Hasil: Hasil penelitian menunjukkan adanya aktivitas analgesic pada dosis 300 mg/KgBB sebesar 62,82% dan dosis 600 mg/kgBB sebesar 81,59%. Simpulan: hasil penelitian menunjukkan bahwa ektrak etanol daun kersen memiliki efek analgesik tertinggi pada dosis 600 mg/KgBB sebesar sebesar 81,59%.
Response of Pineapple Callus (Ananas comosus Merr.) through In-Vitro Colchicines Treatment Nurul Istiqomah; Muh. Shofi
Scientiae Educatia: Jurnal Pendidikan Sains Vol. 7 No. 1 (2018): June (2018)
Publisher : Tadris Biologi Fakultas Ilmu Tarbiyah dan Keguruan IAIN SYEKH NURJATI CIREBON

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24235/sc.educatia.v7i1.1919

Abstract

Pineapple Plant (Ananas comosus (L.) Merr) is a fruit plant that has a high economic value. Increased variety of pineapple preparations lead to increased demand for pineapple fruit. Polyploidation is one way to increase the varieties using colchicine. This study aims to know the pineapple explants of callus response after being treated by colchicine using in vitro method. This research used Group Randomized Design (GRD) which variations concentration of Colchicine 0%, 0.01%, 0.05%, and 0.1%. Parameters were observed to response and thickness of callus of pineapple explants. Data were analyzed using F test and DMRT test in which significance level of 5% with SPSS 17 program. The results showed that pineapple plant explant able to respond colchicine concentration marked with thicker callus. The best colchicine treatment to induce pineapple explants callus was concentration 0.1% of colchicine.
PELATIHAN HALAL BERBASIS SINERGI AKADEMISI DENGAN INDUSTRI SEBAGAI STRATEGI PEMBERDAYAAN MASYARAKAT Faizatul Fitria; Umul Farida; Nurul Istiqomah; Reza Alrayan; Endro Puji Astoko
Jurnal Pengabdian Masyarakat : BAKTI KITA Vol. 7 No. 1 (2026): Nopember - April
Publisher : LPPM Universitas Islam Darul 'Ulum Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52166/baktikita.v7i1.12469

Abstract

Halal training is a community empowerment strategy aimed at increasing the capacity of MSMEs/SMIs to understand the halal concept, certification process, and the application of halal standards in product production and branding. This activity was implemented using a participatory and collaborative approach between academia and industry, involving 30 participants in Kediri Regency. The training method included needs analysis, interactive lectures, technical practice, and evaluation through pre- and post-tests. The evaluation results showed a significant increase in participant understanding, with the high category increasing from 19.35% to 60.48%. Cross-sector collaboration has proven effective in bridging theory and practice, accelerating the halal certification process, and strengthening halal business networks at the local level. This activity contributes to the achievement of sustainable development goals, particularly in the aspects of responsible consumption and production. In addition, this training has had a tangible impact in the form of increased consumer trust in MSME products. The success of this program demonstrates that the integration of academia and industry can be a sustainable model for the development of the halal ecosystem in Indonesia.
PHARMACOGNOSTIC CHARACTERIZATION, PHYTOCHEMICAL SCREENING, AND MICROBIOLOGICAL QUALITY EVALUATION OF BEAN LEAF (Phaseolus vulgaris L.) SIMPLICIA: PHARMACOGNOSTIC CHARACTERIZATION, PHYTOCHEMICAL SCREENING, AND MICROBIOLOGICAL QUALITY EVALUATION OF BEAN LEAF (Phaseolus vulgaris L.) SIMPLICIA Nurul Istiqomah; Dhevi Indah Puspita Sari; Faizatul Fitria; Muh. Shofi; Siti Munawaroh
JURNAL PHARMA BHAKTA Vol 6 No 1 (2026): Mei (2026)
Publisher : FACULTY OF PHARMACY, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/jpb.v6i1.172

Abstract

ABSTRACT Background: Common bean leaves (Phaseolus vulgaris L.) are horticultural plant materials with potential use as traditional herbal medicine due to their diverse secondary metabolites that exhibit various health-promoting properties. Pharmacognostic characterization and quality evaluation are essential to ensure the quality and safety of herbal raw materials. Objective: This study aimed to determine the microscopic characteristics, moisture content, loss on drying, phytochemical profile, and microbiological quality of common bean leaves. Methods: This study was conducted using a descriptive approach. Common bean leaf simplicia was extracted by maceration using 70% ethanol. Microscopic observations were performed on fresh leaves and powdered simplicia. Quality evaluation included the determination of moisture content, loss on drying, phytochemical screening, and microbial contamination through Total Plate Count and Yeast and Mold Count analyses. Results: The extraction process yielded an extract recovery of 11.78%. Microscopic analysis revealed the presence of epidermal tissues, stomata, trichomes, and sclerenchyma. The moisture content and loss on drying were 3.0% and 2.1%, respectively. Phytochemical screening indicated the presence of alkaloids, flavonoids, saponins, tannins, triterpenoids, and steroids. The Total Plate Count and Yeast and Mold Count were 1.6 × 10⁵ CFU/g and 3.1 × 10³ CFU/g, respectively. Conclusion: Common bean leaves possess distinctive pharmacognostic characteristics, contain various potentially bioactive secondary metabolites, and meet microbiological quality requirements for use as herbal raw materials. Keywords: Phaseolus vulgaris L., pharmacognostic characteristics, phytochemical screening, microbiological quality
Co-Authors Aisyah Hadi Ramadani Anikasari, Erni Ariani H. Hutuba Dhevi Indah Puspita Sari Diana Pratiwi Durroh Humairoh Endro Puji Astoko Faizatul Fitria Fera Suwitasari Herlinda Mawardika Inayah Fitri Indra Sabban Intan Puspitasari Ismiy Wahyuni Julianty Akuba Mita Amalia Muh. Shofi Muh. Shofi Muhammad Taupik Novia Agustina Novia Agustina Novia Agustina Reza Alrayan Safitri Fatikasari Salsa Bellamilenia Putri Siti Munawaroh Umul Farida