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EFEKTIVITAS ANALGESIK EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) TERHADAP MENCIT (Mus musculus) Erni Anikasari; Nurul Istiqomah; Mita Amalia
JURNAL PHARMA BHAKTA Vol 2 No 1 (2022): Juni 2022
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Analgesik adalah suatu senyawa yang berkhasiat untuk menekan rasa nyeri. Analgesik memiliki efek samping apabila dikonsumsi dengan dosis berlebih antara lain reaksi hipersensitivitas, gangguan pada usus dan lambung, kerusakan ginjal, serta dapat menyebabkan kerusakan pada hati. Latar Belakang: Secara umum penggunaan obat tradisional dinilai lebih aman dibandingkan obat modern, hal tersebut disebabkan oleh obat tradisional memiliki efek samping rendah jika digunakan secara tepat. Salah satu tanaman obat yang dimanfaatkan untuk pengobatan tradisional yaitu kersen (Muntingia calabura L.). Berdasarkan penelitian sebelumnya dinyatakan bahwa ekstrak etanol daun kersen memiliki efek analgesik. Tujuan: Mengetahui dosis efektif dari ekstrak daun kersen yang dapat digunakan sebagai analgesik. Metode: Pengujian dilakukan secara in vivo mengunakan 12 ekor mencit jantan (Mus musculus) dengan 4 perlakuan. Kelompok kontrol negatif menggunakan Cmc-Na 1%, kelompok kontrol positif menggunakan asam mefenamat 500 mg/kgBB, kelompok perlakuan Ekstrak Etanol Daun Kersen dengan dosis 300 mg/kgBB dan 600 mg/kgBB. Analisis data menggunakan SPSS one way anova. Hasil: Hasil penelitian menunjukkan adanya aktivitas analgesic pada dosis 300 mg/KgBB sebesar 62,82% dan dosis 600 mg/kgBB sebesar 81,59%. Simpulan: hasil penelitian menunjukkan bahwa ektrak etanol daun kersen memiliki efek analgesik tertinggi pada dosis 600 mg/KgBB sebesar sebesar 81,59%.
Response of Pineapple Callus (Ananas comosus Merr.) through In-Vitro Colchicines Treatment Nurul Istiqomah; Muh. Shofi
Scientiae Educatia: Jurnal Pendidikan Sains Vol. 7 No. 1 (2018): June (2018)
Publisher : Tadris Biologi Fakultas Ilmu Tarbiyah dan Keguruan IAIN SYEKH NURJATI CIREBON

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24235/sc.educatia.v7i1.1919

Abstract

Pineapple Plant (Ananas comosus (L.) Merr) is a fruit plant that has a high economic value. Increased variety of pineapple preparations lead to increased demand for pineapple fruit. Polyploidation is one way to increase the varieties using colchicine. This study aims to know the pineapple explants of callus response after being treated by colchicine using in vitro method. This research used Group Randomized Design (GRD) which variations concentration of Colchicine 0%, 0.01%, 0.05%, and 0.1%. Parameters were observed to response and thickness of callus of pineapple explants. Data were analyzed using F test and DMRT test in which significance level of 5% with SPSS 17 program. The results showed that pineapple plant explant able to respond colchicine concentration marked with thicker callus. The best colchicine treatment to induce pineapple explants callus was concentration 0.1% of colchicine.
PELATIHAN HALAL BERBASIS SINERGI AKADEMISI DENGAN INDUSTRI SEBAGAI STRATEGI PEMBERDAYAAN MASYARAKAT Faizatul Fitria; Umul Farida; Nurul Istiqomah; Reza Alrayan; Endro Puji Astoko
Jurnal Pengabdian Masyarakat : BAKTI KITA Vol. 7 No. 1 (2026): Nopember - April
Publisher : LPPM Universitas Islam Darul 'Ulum Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52166/baktikita.v7i1.12469

Abstract

Halal training is a community empowerment strategy aimed at increasing the capacity of MSMEs/SMIs to understand the halal concept, certification process, and the application of halal standards in product production and branding. This activity was implemented using a participatory and collaborative approach between academia and industry, involving 30 participants in Kediri Regency. The training method included needs analysis, interactive lectures, technical practice, and evaluation through pre- and post-tests. The evaluation results showed a significant increase in participant understanding, with the high category increasing from 19.35% to 60.48%. Cross-sector collaboration has proven effective in bridging theory and practice, accelerating the halal certification process, and strengthening halal business networks at the local level. This activity contributes to the achievement of sustainable development goals, particularly in the aspects of responsible consumption and production. In addition, this training has had a tangible impact in the form of increased consumer trust in MSME products. The success of this program demonstrates that the integration of academia and industry can be a sustainable model for the development of the halal ecosystem in Indonesia.