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Relationship Between Knowledge Level and Compliance in Tuberculosis Patients Erni Anika Sari; Kumala Sari PDW; Defi Rafika
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18774

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis which mostly attacks other organs of the body. The source of transmission is TB patients, especially patients who contain TB germs in their sputum. Someone who has high knowledge has also high awereness of health and high motivation to recover. In the treatmnet of tuberculosis succes depends on the support of the family and the knowledge of the patient. If treatment is not complete, it can lead to the emergence of drug- resistant tuberculosis bacteria. If this happens, the germs will spread and control efforts will be more difficult. Purpose: The purpose of this study was to determine whether there was a relationship between the level of knowledge and adherence to the treatment of pulmonary tuberculosis patients. This study uses a analcyticcal sucrvey design with a cross sectional approach with data collection using a questionnaire to respondents of pulmonary tuberculosis patients who meet the inclusion criteria. The data obtained were collected and analyzed using the SPSS program. The results of the chi-square analysis showed 0.05%, 0.036, which means that there is a significant relationship between the level of knowledge and adherence to the treatment of pulmonary tuberculosis patients.
Hubungan Jumlah Peresepan Obat Terhadap Potensially Inapropriate Medications Berdasarkan Beers Criteria 2019 Pasien Diabetes Mellitus Kumala Sari Poespita Dewi Wahyuni; Esti Ambar Widyaningrum; Erni Anika Sari; Dwitania Noerhalizah
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.19752

Abstract

Diabetes melitus can lead to complications if not controlled, the risk of complications in geriatric patiens can lead to an increase in the number of drugs prescribed, so that many geriatric receive polypharmacy drugs. Polypharmacy can be used as a factors to describe Potentially Inappropriate Medications. Potentially Inappropriate Medications are the potential for inappropriate drug use which causes a risk of side effects where there are alternative drug options for the same therapy. This study was to determine the number of drug prescribing for Potentially Inappropriate Medications based on the 2019 Beers Criteria. This studi was an observational descriptive study using retrospective data. The sample used was 195 prescriptions for patients with diabetes mellitus in the period October-December 2020 with purposive sampling technique. Characteristics of the data using the contingency coefficient correlation test. The number of drug prescriptions obtained, a total of 68.21% of patients received 5 kinds of drugs in one prescription based on the assessment of the incidence of Potentially Inappropriate Medications, there were 92.82% of prescriptions indicate an incidence of Potentially Inappropriate Medications. The highest number of Potentially Inappropriate Medications received was category one namely 50,38%. There are difference in the categories of Potentially Inappropriate Medications that patients receive due to diseases suffered by geriatricians where disease that affect many organs cause geriatricians to receive many drugs in health services. Based on a p-value of 0,000 there is a statistically significant relationship between the amount of drug administration with Potentially Inappropriate Medications.
KARAKTER SPESIFIK EKSTRAK DAUN YODIUM (Jatropha multifida L.) DARI TIGA LOKASI TEMPAT TUMBUH DI JAWA TIMUR Dyah Aryantini; Erni Anika Sari; Dani Nanda S.W
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 No. 2: Desember 2021
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v3i1.109

Abstract

Jatropha multifida L. is a plant that has many medicinal properties. The active compounds of this plant include tannins, saponins, flavonoids, and phenols. However, the content of active compounds and the quality of extracts of a medicinal plant cannot be guaranteed to be in the same amount, and this is due to the influence of different growing sites. Therefore it is essential to do standardization. This study aims to characterize iodine leaf extracts from the cities of Kediri, Nganjuk, and Madiun. Specific parameter tests include the section's identity, organoleptic, content of soluble compounds in water and ethanol 96%, and screening for phytochemical flavonoids, tannin alkaloids, and saponins. This study can be concluded that extracts from Kediri, Nganjuk, and Madiun have a thick extract form with a blackish-brown color and have a distinctive odor and bitter taste. Based on phytochemical screening, all extracts contain alkaloids, flavonoids, tannins, saponins. Furthermore, the test levels of soluble compounds in ethanol 96% from Kediri, Nganjuk, and Madiun were 74; 77.70; 73.52%, and the class of soluble compounds in water were 40.90; 31,78, 41.87%.
Patterns of Antihistamin and Corticosteroids Usage In Dermatitis Patients At Primary Public Health Center in Jombang: Pola Penggunaan Antihistamin dan Kortikosteroid Pada Pasien Dermatitis di Puskesmas Kabupaten Jombang Shofiatul Fajriyah; Dea Justisia Ayu Nandya; Erni Anikasari; Fenita Shoviantari
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.328

Abstract

Dermatitis or eczema is a form of the condition in which the layers of the skin (epidermis and dermis) have general inflammation which is usually influenced by endogenous and exogenous factors causing clinical abnormalities in the form of polymorphic efflorescence (erythema, edema, papules, vesicles, scales, lichenification) and itching complaint. This study simed to determine the treatment pattern given to patients with atopic dermatitis and contact dermatitis at the Jelakombo Health Center Jombang. This was an observational study with retrospective data collection. The data sourced used was existing medical records from January to December 2020. Data analysis was carried out descriptively with purposive sampling. The results showed that the most common dermatitis patients were atopic dermatitis (34%) which mostly treated with CTM+Dexamethasone. Patients with allergic contact dermatitis were 38 patients (38%), the most common drug regimen to manage it was Cetirizine+Hydrocortisone ointment. There were 28 patients (28%) with irritant contact dermatitis, which mostly treated with Cetirizine+Hydrocortisone Ointment followed by CTM + Dexamethasone. This study concluded that the drug regimen for the three types of dermatitis was almost the same, namely a combination of oral and topical antihistamines and corticosteroids. The antihistamines used were first-generation antihistamines (CTM) and second-generation (Cetirizine and Loratadine). Further assessment related to whether the sedation effect was wanted or it was disturbing side effect is needed. The widely used oral corticosteroid was dexamethasone, which is a high-potency corticosteroid, so its use must be judicious. Topical corticosteroids were hydrocortisone ointments that include low potency topical corticosteroids which are the first line of atopic dermatitis and allergic contact dermatitis.
EVALUASI PENGGUNAAN CLOPIDOGREL TERHADAP LAMA RAWAT PASIEN STROKE RAWAT INAP DI RSUD KOTA KEDIRI Erni Anikasari; Shofiatul Fajriyah; Mufthirza Ramdini; Sri Endang I
JURNAL PHARMA BHAKTA Vol 1 No 1 (2021): Mei 2021
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Latar Belakang : Di Indonesia diperkirakan setiap tahun terjadi 500.000 penduduk terkena serangan stroke, 25% orang meninggal sedangkan sisanya mengalami cacat ringan bahkan bisa menjadi cacat berat. Terapi antiplatelet digunakan untuk mengurangi kejadian stroke pada pasien yang beresiko tinggi terjadinya atherosklerosis dan penyakit serebovaskuler yang penyebabnya simtomatik. Antiplatelet yang digunakan adalah aspirin, clopidogrel baik monoterapi atau kombinasi. Adanya pemilihan penggunaan Clopidogrel tunggal sebagai antiplatelet menjadi alasan penulis untuk melakukan penelitian bagaimana efek dari pemberian Clopidogrel terhadap lama rawat inap pada pasien stroke. Metode Penelitian: Peneliti mengunakan metode penelitian diskriftif dengan menggunakan data retrospektif yang berasal dari data Rekam medis pasien. Sampel pada penelitian ini adalah pasien stroke rawat inap yang menggunakan Clopidogrel di RSUD Gambiran periode Januari-Juni 2018. Hasil Penelitian: Sampel penelitian didapatkan 43 pasien stroke rawat inap yang menggunakan Clopidogrel. Dimana lama waktu pemberian dan lama rawat inap pasien menjadi bahan evaluasi. Kesimpulan: Berdasarkan penelitian ini dapat disimpulkan bahwa rata-rata pemberian Clopidogrel lebih pendek dibandingkan lama rawat inap pasien stroke iskemik, meskipun dapat dikatakan bahwa lama rawat inap pasien stroke termasuk singkat.
EFEKTIVITAS ANALGESIK EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) TERHADAP MENCIT (Mus musculus) Erni Anikasari; Nurul Istiqomah; Mita Amalia
JURNAL PHARMA BHAKTA Vol 2 No 1 (2022): Juni 2022
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Analgesik adalah suatu senyawa yang berkhasiat untuk menekan rasa nyeri. Analgesik memiliki efek samping apabila dikonsumsi dengan dosis berlebih antara lain reaksi hipersensitivitas, gangguan pada usus dan lambung, kerusakan ginjal, serta dapat menyebabkan kerusakan pada hati. Latar Belakang: Secara umum penggunaan obat tradisional dinilai lebih aman dibandingkan obat modern, hal tersebut disebabkan oleh obat tradisional memiliki efek samping rendah jika digunakan secara tepat. Salah satu tanaman obat yang dimanfaatkan untuk pengobatan tradisional yaitu kersen (Muntingia calabura L.). Berdasarkan penelitian sebelumnya dinyatakan bahwa ekstrak etanol daun kersen memiliki efek analgesik. Tujuan: Mengetahui dosis efektif dari ekstrak daun kersen yang dapat digunakan sebagai analgesik. Metode: Pengujian dilakukan secara in vivo mengunakan 12 ekor mencit jantan (Mus musculus) dengan 4 perlakuan. Kelompok kontrol negatif menggunakan Cmc-Na 1%, kelompok kontrol positif menggunakan asam mefenamat 500 mg/kgBB, kelompok perlakuan Ekstrak Etanol Daun Kersen dengan dosis 300 mg/kgBB dan 600 mg/kgBB. Analisis data menggunakan SPSS one way anova. Hasil: Hasil penelitian menunjukkan adanya aktivitas analgesic pada dosis 300 mg/KgBB sebesar 62,82% dan dosis 600 mg/kgBB sebesar 81,59%. Simpulan: hasil penelitian menunjukkan bahwa ektrak etanol daun kersen memiliki efek analgesik tertinggi pada dosis 600 mg/KgBB sebesar sebesar 81,59%.
POLA PERESEPAN OBAT PADA PASIEN MYALGIA DI PUSKESMAS NGANJUK Shofiatul Fajriyah; Erni anikasari
JURNAL PHARMA BHAKTA Vol 4 No 1 (2024): Mei 2024
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Latar belakang: Myalgia paling sering dikaitkan dengan keseleo atau kaku otot. Gejala yang sering muncul adalah kemerahan di lokasi cedera, nyeri tekan, bengkak, dan demam. Nyeri otot adalah masalah medis utama dimana mayoritas (60% hingga 85%) dari populasi pernah mengalami nyeri punggung (nonspesifik). Tujuan: Penelitian ini bertujuan untuk mengetahui pola pengobatan pada pasien myalgia di Puskesmas Nganjuk Tahun 2020. Metode: Metode deskriptif observasional dengan pengumpulan data secara retrospektif. Penelitian ini menggunakan data rekam medis pasien myalgia dengan teknik sampling yaitu total sampling. Analisis data dilakukan secara deskriptif dan disajikan dalam bentuk prosentase. Hasil: Hasil penelitian menunjukkan sebanyak 39 pasien didiagnosa myalgia. Jenis analgesik yang digunakan adalah Asam Mefenamat, Natrium Diklofenak, Metampiron, Parasetamol dan Ibuprofen. Suplemen yang digunakan pada pasien myalgia adalah Kalsium Laktat, Vitamin B kompleks, vitamin B1, Multivitamin dan Ferrous fumarat. Pola pengobatan pasien myalgia meluputi analgesik tunggal (20,5%), kombinasi 2 analgesik (10,3%), kombinasi analgesik + suplemen (66,7%) dan kombinasi 2 suplemen (2,5%).  Simpulan : Pola peresepan obat yang paling banyak adalah kombinasi Asam Mefenamat dan Kalsium Laktat
Analisis Pengaruh Kualitas Layanan Informasi Swamedikasi Online Berbasis Whatsapp Bot Terhadap Kepuasan Masyarakat Widyaningrum, Esti Ambar; Yestari, Farah Eka Julia; Sari, Erni Anika; Srihartini, Indah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1158.686 KB) | DOI: 10.35617/jfionline.v14i2.73

Abstract

Abstract: The innovation of online self-medication information services, one of which is based on WhatsApp Bot, is needed to make it easier for people to find self-medication information for the community. This innovation needs to be continuously developed so that it can provide adequate information services, can increase knowledge and provide satisfaction to users. The purpose of this study was to determine the level of community satisfaction with online self-medication services based on WhatsApp Bot and the effect of expectations on satisfaction using the RATER dimension (Reliability, Assurance, Tangible, Empathy, Responsiveness) in the community of Talun Village, Blitar Regency. The method used in this study is an analytical survey using a cross sectional design. Sampling was done by purposive sampling technique and obtained 264 respondents from the residents of Talun Village, Blitar Regency. Gap analysis was obtained at -0.10 with a level of satisfaction that was not satisfied with the services that had been provided with detailed attributes including: layout, absence of constraints, valid and reliable information, complete information, attention to user needs and the speed of customer service responding, needs to be improved to increase user satisfaction. Spearman rank correlation test obtained P value 0.05 and correlation coefficient value of 0.644. The community is not satisfied with this information service and there is an influence between the quality of information source services and satisfaction in the community of Talun Village, Blitar Regency with a positive correlation and strong correlation strength so it is necessary to develop this Whatsapp Bot-based self- medication information service.
CASE STUDY OF THE USE OF WOUND CARE MEDICATION IN DIABETES MELLITUS PATIENTS WITH COMPLICATIONS Anikasari, Erni; Emelia Cantessa, Imelda
JURNAL PHARMA BHAKTA Vol 5 No 1 (2025): Mei 2025
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Hiperglikemia merupakan karakteristik penyakit Diabetes Mellitus yang disebabkan karena adanya gangguan insulin yaitu karena sekresi nya maupun sensitivitas insulin. Diabetes Mellitus kronik menjadi penyebab ganguan kardiovakusler, sehingga pengunaan terapi obat beragam. Penelitian ini bertujuan untuk mengetahui pola penggunaan obat rawat lukan pada pasien DM dengan komplikasi. Metode penelitian yang digunakan adalah observasional deskriptif dengan pengumpulan data dari rekam medis pasien DM yang mengalami komplikasi. Data yang dianalisis meliputi jenis obat yang paling sering diresepkan, frekuensi penggunaan, serta kepatuhan pasien. Hasil penelitian menunjukkan bahwa Terapi obat yang digunakan meliputi cairan infus NaCl, injeksi levofloxacin, injeksi ranitidin, injeksi ondancetron, injeksi santagesik, injeksi ceftriaxon, injeksi dopamine, meylon, serta obat oral seperti paracetamol tablet, metformin tablet, dan azithromycin tablet untuk mengatasi nyeri dan infeksi, serta terapi rawat luka dengan cairan NaCl dan salep gentamicin. Kesimpulan dari penelitian ini adalah penggunaan obat rawat luka pada pasien Diabetes Mellitus adalah cairan NaCl dan Genatamisin.
Pola Penggunaan dan Rasionalitas Obat Stroke Iskemik di RSUD Dr. Saiful Anwar Anikasari, Erni; Widyaningrum, Esti Ambar; Wahyuni, Kumalasari Poespita Dwi; Astuti, Lely Winduhani; Lailatul M., Nur
KUNIR: JURNAL FARMASI INDONESIA Vol 2 No 1 (2024): JULI
Publisher : Program Studi Farmasi (S-1), Fakultas Ilmu Kesehatan, Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/kjfi.v2i1.563

Abstract

Stroke adalah suatu sindrom klinis yang ditandai dengan hilangnya fungsi otak secara akut dan dapat menimbulkan kematian. Serangan iskemia sementara atau Transient ischemic attacks (TIAs) adalah penurunan fungsi iskemia sistem syaraf utama iskemia menurun selama kurang dari 24 jam dan biasanya kurang dari 30 menit. Hal ini terjadi ketika pasokan darah ke otak berkurang atau terhambat karena hal-hal tertentu yang mengarah ke kurangnya kadar oksigen dalam sel-sel otak secara mendadak. Dalam beberapa menit, sel-sel otak bisa rusak dan kehilangan fungsinya. Tujuan dari penelitian ini yaitu untuk mengetahui pola penggunaan obat dan rasionalitas obat pada pasien stroke iskemik yang ditinjau dari parameter tepat diagnosa, tepat indikasi, tepat obat, dan tepat dosis. Penelitian ini dilakukan di RSUD Dr. Saiful Anwar Kota Malang Tahun 2021 dan merupakan penelitian observasional dengan pengambilan data dilakukan dengan secara retrospektif dan dianalisis secara deskriptif. Pengambilan data sebanyak 69 pasien menggunakan metode teknik slovin. Hasil penelitian ini menunjukkan pola penggunaan obat stroke iskemik yaitu kombinasi neuroprotektan + antiplatelet + antihipertensi + antidislipidemia sebanyak 49 pasien. Hasil penelitian rasionalitas obat menunjukkan hasil tepat indikasi 100%, tepat pasien 100%, tebat obat 100%, dan tepat dosis 100%.