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PENGEMBANGAN MODUL PRAKTIKUM BIOLOGI YANG MEMANFAATKAN BAHAN ALAM SEBAGAI SUMBER BELAJAR BAGI SISWA DI SEKOLAH MENENGAH ATAS (SMA) Mariana Rengkuan Rengkuan; Dian H O Howan
ABDIMAS: JURNAL PENGABDIAN KEPADA MASYARAKAT Vol 9, No 02 (2016): DESEMBER 2016
Publisher : LPPM UNIMA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1008.341 KB) | DOI: 10.36412/abdimas.v9i02.576

Abstract

The aim of this research is to generate biology laboratory work module which utilize natural products as learning resource for students in senior high school. This module developed using Borg and Gall model which has been adapted with the needs and aims of this research, therefore, it gained four major stages that will be passed. These stages namely: needs analysys and literature study, matter development (based on needs), expert validation and field test (experimental class). On expert validation limited to matter expert validator whilst for field test, it was decided on students from XII science class as experimental class. The result of this research shown that laboratory module that utilized natural products can be used as learning resource for students in senior high school.
Optimasi dan validasi metode analisis residu klorpirifos menggunakan High Performance Liquid Chromatography (HPLC) Abdon Saiya; Dokri Gumolung; Dian Herlinda Octorina Howan
Jurnal Kimia Fullerene Vol 2 No 2 (2017): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (660.414 KB) | DOI: 10.37033/fjc.v2i2.20

Abstract

One of the most sensitive and selective instrumentation techniques for the analysis of pesticide residues in vegetables at a high level is High Performance Liquid Chromatography (HPLC). To obtain optimum result of measurement, optimization and validation of measurement method is needed. The purpose of this research is to optimize and validate the determination of chlorpyrifos concentration by HPLC method, so it can be used for analysis of chlorpyrifos residues in samples of cabbage vegetables taken from some traditional markets in North Sulawesi. Optimized chromatographic parameters are the composition of mobile phase of water and acetonitrile, mobile phase flow rate, and the volume of the sample injection. While the validated measurement parameters include precision, linearity, detection limits, and quantitation limits. Based on the results obtained using Zorbax Eclipse Plus C18 column, the optimum condition of HPLC was achieved at λmax of 289 nm, mobile phase composition of water : acetonitrile was 10:90, mobile phase flow rate of 0.70 mL/min, and sample injection volume of 15 μL. The result of validation of analytical method shows that analytic performance of determination of chlorpyrifos with HPLC method is very good, it is indicated by measurement parameter such as precision shown with coefficient of variation (CV) was 0,2086%, linearity indicated by correlation coefficient (r) was 0.9963, the detection limit (LOD) of 0.67 ppm, and the quantitative limit (LOQ) of 2.24 ppm, which all meet the requirements. The results of this study indicate that this method can be used for analysis of chlorpyrifos residues in cabbage vegetable samples.
Screening Senyawa Pandu Inhibitor Endositosis dengan Metode Molecular Modelling Dian Herlinda Octorina Howan
Jurnal Kimia Fullerene Vol 3 No 1 (2018): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (512.297 KB) | DOI: 10.37033/fjc.v3i1.32

Abstract

The purpose of this research is to search for compound inhibitor endocytosis by using Molecular Modeling program. Screening is performed on approximately 800,000 compounds derived from several commercial companies. From the results of virtual screening obtained 320 hits, and of this number only 175 compounds that can be obtained to test its biological activity. Biological tests showed that there were 7 compounds with moderate endocytosis inhibition capability (IC50 = 50-170 μM) to good inhibition (IC50 <50 μM). The compounds are: compound 1 (IC50 = 42 ± 4 μM), compound 2 (IC50 = 83 ± 8 μM), compound 3 (IC50 = 135 ± 58 μM), compound 4 (IC50 = 151 ± 18 μM) compound 5 (IC50 = 144 ± 18 μM), compound 6 (IC50 = 13 ± 4 μM), and compound 7 (IC50 ~ 170 μM).
Isolasi dan identifikasi metabolit sekunder dari ekstrak butanol pegagan [Centella asiatica (L) urban] Dian Herlinda Octorina Howan
Jurnal Kimia Fullerene Vol 2 No 2 (2017): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (369.068 KB) | DOI: 10.37033/fjc.v2i2.16

Abstract

A triterpenoid tetrahydroxy of 3.1 mg has been isolated from the butanol extract of Centella asiatica. Separation and purification were performed using several stages of column chromatography, and identification was performed by taking the proton nuclear magnetic resonance spectrum (NMR-1H). The spectral data of NMR-1H isolate F6.1 indicates the presence of signals at a chemical shift (δ in ppm) 0.89 (d, J = 6.35 Hz), 0.94 (d, J = 6.35 Hz), 1.05 (s), 1.06 (s), 2 CH3, 1.12 (s), 2 hydroxy methylene protons at δ 3.78 (t; J = 4.88 Hz), and 3.99 (t J = 4.88 Hz), 3 methyl protons attached to the hydroxylated carbon each at δ 4.24 (m), 4.22 (m), and 3.72 (d; J = 10.7 Hz) Based on RMI-1H spectrum data it can be proposed that isolate F6.1 is brahmic acid, 2α, 3β, 6β, 23-tetrahydroxy-28-oat-12en.
Kajian kalor reaksi tembaga sulfat (CuSO4.5H2O) melalui prototipe kalorimeter Dian Herlinda Octorina Howan
Jurnal Kimia Fullerene Vol 4 No 1 (2019): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.177 KB) | DOI: 10.37033/fjc.v4i1.46

Abstract

Determination of dissolution heat reaction of copper sulfate hydrate, CuSO4.5H2O and copper sulfate anhydrous, CuSO4 using a calorimeter prototype was carried out. The initial stage is carried out by measuring the calorimeter constant and then measuring the heat of copper sulphate dissolution using Hess's Law to determine the heat of reaction indirectly. The results obtained by the dissolution reaction reaction of copper sulfate CuSO4.5H2O and copper sulfate anhydrous CuSO4 respectively were 723,318 J and 748,26 J.
Studi Kandungan Kimia Ekstrak Buah Pakoba Merah (Syzygium sp) Jenny Kumajas; Dian Herlinda Octorina Howan
Jurnal Kimia Fullerene Vol 3 No 2 (2018): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.01 KB) | DOI: 10.37033/fjc.v3i2.39

Abstract

Red Pakoba (Syzygium sp) is a plant endemic to North Sulawesi. This study aims to find secondary metabolites from red pakoba fruit extract (Syzygium sp). The process is carried out by extraction and phytochemical testingFrom the phytochemical filtration results obtained the extract of red Pakoba fruit contains phenol compounds, terpenes, steroids and flavonoids. It needs further investigation the activity and the structure of the active compound from red pakoba fruit extract.
PELATIHAN PEMBUATAN APLIKASI BERBASIS ANDROID TERINTEGRASI MODEL PEMBELAJARAN BERBASIS INKUIRI PADA GURU DI SMAN 1 MANADO Desire Atna Sridanty Rumondor; Jakub Saddam akbar; Dian Herlinda Octorina Howan; Chaleb Paul Maanari; Djakariah Djakariah
BHAKTI NAGORI (Jurnal Pengabdian kepada Masyarakat) Vol. 4 No. 2 (2024): BHAKTI NAGORI (Jurnal Pengabdian kepada Masyarakat) Desember 2024
Publisher : LPPM UNIKS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36378/bhakti_nagori.v4i2.3905

Abstract

Pelatihan pembuatan aplikasi berbasis Android yang terintegrasi dengan model pembelajaran berbasis inkuiri di SMAN 1 Manado merupakan upaya untuk meningkatkan kompetensi guru dalam memanfaatkan teknologi untuk mendukung pembelajaran abad ke 21. Pelatihan ini mencakup pengenalan teori pengembangan aplikasi Android, prinsip-prinsip pembelajaran berbasis inkuiri, serta strategi integrasi keduanya dalam pembelajaran. Hasil pelatihan menunjukkan bahwa peserta, yaitu guru-guru di SMAN 1 Manado, mampu memahami teori dan merancang aplikasi sederhana yang relevan dengan kebutuhan pembelajaran. Integrasi antara teknologi Android dan model pembelajaran berbasis inkuiri terbukti efektif dalam meningkatkan kualitas pembelajaran, menciptakan pengalaman belajar yang interaktif, menarik, dan bermakna. Refleksi peserta mengungkapkan apresiasi terhadap pelatihan ini, yang dinilai memberikan wawasan baru serta keterampilan yang aplikatif. Dengan pendampingan berkelanjutan, pelatihan ini diharapkan menjadi langkah awal dalam mendorong inovasi pembelajaran berbasis teknologi di sekolah, sekaligus menjadi model bagi pengembangan pendidikan di era digital.
Pelatihan Penulisan Paragraf Deskriptif Menggunakan Graphic Organizers Lambe, Livianni; Maukar, Merlin Maya; Wongkar, Yapi Henri; Rengkuan, Mariana; Howan, Dian Herlinda Octorina
Jurnal ABDIRAJA Vol 8 No 1 (2025): Jurnal Abdiraja
Publisher : LPPM Universitas Wiraraja Sumenep, Jalan Raya Sumenep Pamekasan KM. 5 Patean Sumenep 69451, Telp. (0328) 673399 Fax. (0328) 673088

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24929/adr.v8i1.4023

Abstract

Ada 2 jenis keterampilan berbahasa yang harus dikuasai oleh pelajar yaitu ketrampilan pasif dan produktif. Keterampilan produktif adalah berbicara dan menulis. Dalam belajar bahasa Inggris, kecapan berbicara dan menulis sangat sukar dikuasai oleh pelajar. Hal ini juga dialami oleh pelajar di Pengembangan Pendidikan Anak Ikhtus Wilayah Manado Barat Daya. Untuk mengatasinya, diberikan pelatihan menulis esai dalam bentuk paragraf yaitu paragraph deskriptif dengan menerapkan graphic organizers (GO). Pelaksanaan kegiatan tersebut dilakukan beberapa tahap selama 6 bulan. Kegiatan ini memberikan penjelasan tentang menulis paragraph dan strukturnya, paragraphs deskriptif dan strukturnya serta bagaimana struktur paragraph deskriptif diterapkan pada alat pembelajaran grafis yang visual atau graphic organizers. Peran alat belajar tersebut sebagai brainstorming untuk mempermudah pelajar mengingat elemen-elemen pada paragraph descriptive. Paragraph deskriptif yang diajarkan adalah menggambarkan orang. Hasil menunjukkan graphic organizers yang disesuaikan dengan ciri-ciri paragraph deskriptif membantu siswa untuk menulis esai sesuai elemen penyusunnya.
Pengaruh Pembelajaran Praktikum Kimia Berbasis Inkuiri Terbimbing terhadap Keterampilan Menyimpulkan Siswa pada Materi Kelarutan dan Hasil Kali Kelarutan Akbar, Jakub Saddam; Djakariah, Djakariah; Rumengan, Stefan Marco; Waworuntu, Freetje; Dumanaw, Varisky Abraham; Rumondor, Desire Atna Sridanty; Akbar, Ayu Febrianti; Howan, Dian Herlinda Octorina
SCIENING : Science Learning Journal Vol. 5 No. 2: Desember 2024
Publisher : Jurusan Pendidikan IPA FMIPA Universitas Negeri Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53682/slj.v5i2.11261

Abstract

Penelitian ini bertujuan untuk menganalisis pengaruh pembelajaran praktikum kimia berbasis inkuiri terbimbing terhadap keterampilan menyimpulkan siswa pada materi kelarutan dan hasil kali kelarutan. Desain penelitian yang digunakan adalah eksperimen semu dengan instrumen berupa tes untuk mengukur keterampilan menyimpulkan. Data hasil penelitian dianalisis menggunakan analisis statistik. Hasil analisis menunjukkan bahwa siswa yang mengikuti praktikum dengan metode inkuiri terbimbing memiliki keterampilan menyimpulkan yang lebih tinggi, dengan persentase nilai sebesar 81,9%, dibandingkan dengan siswa yang mengikuti metode praktikum verifikasi yang memperoleh nilai sebesar 73,6%. Temuan ini mengindikasikan bahwa pembelajaran praktikum kimia berbasis inkuiri terbimbing lebih efektif dalam meningkatkan keterampilan menyimpulkan siswa pada materi kelarutan dan hasil kali kelarutan.
Quantitative Determination of Ascorbic Acid Content in Two Varieties of Bird’s Eye Chili (Capsicum frutescens L.) using UV-Vis Spectrophotometry Howan, Dian; Saiya, Abdon; Pongoh, Emma
Jurnal Kimia Fullerene Vol 10 No 2 (2025): Fullerene Journal Of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37033/fjc.v10i2.745

Abstract

This study quantified and compared the ascorbic acid content in green and red bird's eye chili (Capsicum frutescens) using UV-Vis spectrophotometry. The method was optimized by determining the maximum wavelength of ascorbic acid in an acid-stabilized solution, found to be 231 nm. A calibration curve was constructed with standard solutions (25-100 ppm), yielding a linear equation y = 0.0514x + 0.6032 (R² = 0.9361). Sample extracts were prepared and analysed in triplicate at this wavelength. The results demonstrated a significant difference in ascorbic acid concentration between the two varieties. The red chili exhibited a higher concentration of 34.39 ppm in the measured solution, corresponding to 0.90% (b/b) of the fresh weight. In contrast, the green chili contained 23.95 ppm (0.60% b/b). This indicates a 50% higher ascorbic acid content in the mature red fruit. The study concludes that ripening significantly enhances the vitamin C content in bird's eye chili, and the red variety is a nutritionally superior source. The validated method proved effective for the quantitative analysis of ascorbic acid in complex food matrices.