Andi Wardihan Sinrang
Department of Physiology, Faculty of Medicine/Hasanuddin University, Wahidin Sudirohusodo Hospital, Makassar

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EFFECT OF PLASMA ANGIOTENSIN CONVERTING ENZYM IN ERECTILE DYSFUNCTION Sinrang, Andi Wardihan
Indonesian Journal of Urology Vol 21 No 1 (2014)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v21i1.23

Abstract

Objective:The aim of this study was to know the effect of aging and I/D angiotensin converting enzymes (ACE) gene polymorphisms in modulating plasma ACE level in erectile dysfunction(ED) subjects.Material & method:This case control study carried out in Makassar with 83 male subjects (49 ED subjects and 34 normal subjects). International Index of Erectile Function-5 was used for ED diagnosis while plasma ACE level and genotyping ACE gene examined with ELISA test and Rigat PCR method respectively.Results:The data showed that plasma ACE level siginificantly higher in ED group compared to normal group, while the plasma ACE level consistently raised following the increased of age in ED group but did not statistically significant (p>0.05) compare to normal group. DD genotype in ED group had mean plasma ACE higher compared to ID and II subjects eventhough did not statistically significant.Conclusion: The high level of ACE plasma appeared to have a pivotal rule in ED mechanisms as well as in older ED subjects. DD genotype partly modulated the raising of plasma ACE in ED subject comprared to ID and II genotype.  Keywords: Plasma ACE level, erectile dysfunction.
ENDOTHELIN-1, NITRIC OXIDE, AND RATIO OF ET1/NO IN ERECTILE DYSFUNCTION Sinrang, Andi Wardihan
Indonesian Journal of Urology Vol 18 No 2 (2011)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v18i2.70

Abstract

Objective: The aim of this study was to observe the level of Endothelin-1 (ET-1), Nitric oxide (NO), and the ratio of ET-1/NO in Erectile dysfunction (ED) and normal subjects. Material & method: This case-control study was carried out in Makassar with subjects recruited from outpatient clinic at Wahidin Sudirohusodo Hospital and divided into 2 groups (56 subjects DE and 34 subjects normal). ET-1 and NO plasma were measured by ELISA technique according to protocol. Results: The data showed that mean value of ET-1 in erectile dysfunction subjects was significantly higher (p < 0,05), while NO was significantly lower (p < 0,05) in DE groups compared to normal groups. The ratio of ET-1/NO was also significantly different between both groups. Conclusion: We concluded that level of plasma ET-1, plasma NO, and the ET-1/NO ratio are important factors involved in ED pathomechanism. Keywords: Erectile dysfunction, plasma endothelin-1, plasma nitric oxide, ratio ET-1/NO.
Faktor-faktor yang Mempengaruhi Kadar Hemoglobin pada Wanita Prakonsepsi: Studi Kasus Kontrol Syariena, Syariena; Hidayanti, Healthy; Usman, Andi NilawatI; Sinrang, Andi Wardihan; A, Andi Sumidarti
Journal of Language and Health Vol 5 No 3 (2024): Journal of Language and Health
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jlh.v5i3.4903

Abstract

Kesehatan wanita pada masa prakonsepsi merupakan langkah untuk melindungi kesehatan ibu dan anak yang mungkin terjadi di kemudian hari. Pemeriksaan hemoglobin sebelum kehamilan dilakukan untuk menghindari anemia. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kadar hemoglobin pada wanita prakonsepsi. Penelitian ini menggunakan metode observasional dengan rancangan studi kasus-kontrol yang melibatkan 118 calon pengantin prakonsepsi dan dilaksanakan di Kantor Urusan Agama Provinsi Sulawesi Selatan, Indonesia, pada bulan Juli 2022. Sampel penelitian diklasifikasikan menjadi kelompok kadar hemoglobin rendah (59 responden) dan kelompok kadar hemoglobin normal (59 responden). Sampel dipilih secara purposive sampling sesuai dengan kriteria inklusi dan eksklusi. Data dikumpulkan menggunakan lembar kuesioner, food recall 24 jam dan hasil sampel darah kapiler. Analisis data menggunakan uji chi-square. Hasil analisis menunjukkan bahwa usia, pendidikan, status gizi, dan status ekonomi berkorelasi signifikan dengan kadar hemoglobin pada wanita prakonsepsi (P < 0,05). Pada regresi logistik, faktor yang berhubungan dengan hemoglobin adalah usia (OR 13,162), status gizi (OR 11,416), dan pendidikan (OR 0,018). Usia, pendidikan, status gizi, dan status ekonomi dapat memengaruhi kadar hemoglobin pada wanita prakonsepsi. Usia dan status gizi merupakan faktor yang paling berpengaruh.
The Effectiveness of Web-Based E-WoHealth on Compliance with Consumption of Iron Tablets in Young Women Yulianti, Desak Made; Ahmad, Mardiana; Baso, Yusring Sanusi; Sinrang, Andi Wardihan; Usman, Andi Nilawati; Prihantono, Prihantono
JURNAL INFO KESEHATAN Vol 21 No 2 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss2.1178

Abstract

Utilization of technological media in the field of education and health can increase public knowledge in efforts to prevent anemia, especially in young women. One of the efforts to prevent anemia and increase adherence to taking iron tablets is by using Web-based educational media (E-WoHealth) about iron tablets supplemented with a tablet supplement consumption control card. This research aims to develop Web-based E-WoHealth media and its effect on the level of adherence to the consumption of blood supplement tablets. This study used the Research and development (R&D) method with the Borg & Gall development model and the Pre-experimental Design quantitative method using the One Group Pretest-Postest approach. The sample in this study was 80 girls in grades VII and VIII of SMP Negeri 11 Gorontalo City, determined by purposive sampling technique. Statistical tests used the McNemar test and the Chi-Square test. The results of the McNemar test showed differences in the measurement results before and after being given the Web-based E-WoHealth media with a p-value of 0.000 <0.05 meaning that the Web-based E-WoHealth media was effective in increasing adherence to consumption of iron supplement tablets (TTD) in class VII and class VIII girls and the results of the Chi-Square P-Value test were 0.822 > 0.05 meaning that there was no difference in adherence between class VII and VII girls. This study recommends the application of WEB-based E-WoHealth media equipped with an iron supplement control card to increase adherence and monitor iron supplement consumption.
The Effectiveness of Na'o Beps Animation Video on Young Women's Knowledge and Skills in Early Detection of Breast Cancer by Breast Self-Examination (BSE) Pombaile, Veny Delvia; Sutinah, Sutinah; Ahmad, Mardiana; Sinrang, Andi Wardihan; Nontji, Werna; Stang, Stang
JURNAL INFO KESEHATAN Vol 21 No 2 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss2.1181

Abstract

Breast cancer ranks first in cancer-related deaths in women in the world, which are generally found at an advanced stage. Breast self-examination (BSE) that has been used since puberty can detect breast cancer symptoms earlier so that treatment can achieve a survival probability of 90% or more. Animated video is one of the developments in health education media that is in line with advances in digital technology. This study aims to determine the effectiveness of the Na'o Beps animated video on improving the skills of young women in performing breast self-examination (BSE). This research is a research & development model of 4D development (define, design, develop, disseminate) and the research design used a pre-experimental design with a one-group pretest-posttest design. The sample in this study was all grade VIII students at SMP Negeri 14 Gorontalo City, Gorontalo Province in 2022, a total of 36 students. The sampling technique used purposive sampling. Data analysis in this study was carried out by the Wilcoxon test. The results showed that there were significant differences in the knowledge (p=0.00) and skills (p=0.000) of female adolescents regarding breast self-examination (BSE) after the intervention with the Na'o Beps animation video. Conclusion Health education using animated video media is effective in increasing the knowledge and skills of young women about breast self-examination (BSE) so that it can be used as an alternative medium in providing health education.