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All Journal Jurnal Kesehatan Hesti Wira Sakti UNEJ e-Proceeding Journal Of Vocational Health Studies Jurnal Kesehatan Mesencephalon Syntax Literate: Jurnal Ilmiah Indonesia Health Sciences and Pharmacy Journal Jurnal Kesehatan Ilmiah Indonesia / Indonesian Health Scientific Journal Jurnal Ners Jurnal ABM Mengabdi JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Jurnal Pengabdian kepada Masyarakat Wahana Usada Jurnal Pengabdian Masyarakat : Pemberdayaan, Inovasi dan Perubahan International Journal of Health and Pharmaceutical (IJHP) Jurnal Sehat Indonesia (JUSINDO) Jurnal Indonesia Sosial Sains Innovative: Journal Of Social Science Research Journal of Mandalika Literature Jurnal Pengabdian Soepraoen Journal Of Health Innovation And Community Services Journal of Innovative and Creativity Indonesian Journal of Global Health Research
Mayang Wulandari
ITSK RS Dr Soepraoen
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Acupuncture and NSAIDs Reduce Neurogenic-Pain and Matrix Degradation Biomarkers in a Rat Model of Osteoarthritis Mayang Wulandari; Achmad Jaelani; Fitria Novitasari; Wahyudha Ngatiril Lady
Indonesian Journal of Global Health Research Vol. 8 No. 1 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i1.1372

Abstract

Osteoarthritis (OA) is a degenerative joint disease characterized by neurogenic pain and cartilage degradation, with serum biomarkers (SP, NGF, COMP, and MMP-13) serving as indicators of pain signaling, tissue damage, and treatment effects. This study aimed to compare the effects of acupuncture and a nonsteroidal anti-inflammatory drug (NSAID) on neurogenic pain and cartilage degradation biomarkers in a rat OA model. A randomized post-test-only experimental study was conducted using 32 male Wistar rats selected by purposive sampling and randomly allocated into four groups (n=8/group): healthy control, OA control, OA+acupuncture, and OA+NSAID. OA was induced by intra-articular monosodium iodoacetate. Acupuncture was administered at ST35, SP9, and GB34 for 10 sessions, while the NSAID group received oral meloxicam. Serum biomarkers were measured by ELISA and analyzed using one-way ANOVA with Tukey’s HSD (p<0.05). Results: Significant differences were observed among all groups for each biomarker (p<0.001) with large effect sizes. Biomarker levels followed the pattern A < M ≈ S < K. Both treatment groups showed significant reductions compared to OA controls, with no significant difference between acupuncture and NSAID. Acupuncture and NSAID treatments produced comparable improvements in OA-related biomarkers, supporting multimodal therapeutic approaches for OA.
Acupuncture Treatment for Patients with Xuan Yun Syndrome with Kidney Yin Deficiency and Liver Hyperactivity at Griya Sehat Metta Tegal Alur, West Jakarta Junet; Mayang Wulandari; Chantika Mahadini; Amal
Jurnal Indonesia Sosial Sains Vol. 7 No. 3 (2026): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v7i3.2280

Abstract

Vertigo or Xuan Yun is a vestibular disorder causing spinning sensations and significantly affecting quality of life. Pharmacological management may cause adverse effects; therefore, complementary therapy is required. This study aimed to analyze the effectiveness of acupuncture care in a patient diagnosed with Kidney Yin Deficiency and Liver Yang Rising syndrome. A single-case study design was applied to a 43-year-old female with chronic vertigo. Five therapy sessions were conducted. Evaluation used the Visual Analog Scale (VAS) and Dizziness Handicap Inventory (DHI). Results showed a decrease in VAS score from 7 to 0 and DHI score from 56 to 8. Clinical improvement was also observed in Wang, Wen, and Qie examinations. Acupuncture was effective in reducing vertigo intensity and improving functional activity through Qi regulation and Yin–Yang balance restoration.
Co-Authors Achmad Jaelani Agam Ferry Alfie Vere Likhie Alice Alice Amal Amal Prihartono Amal Prihatono Candra , Leny Chantika Mahadini Dewi, Helena Laksmi Dion Kunto Adi Patria Feby Efendi Fitria Novitasari Ikhwan Abdullah Indrawati Setyono Junet Khiong, Tjhia Khie Leny Candra Leny Candra Kurniawan Mahadinia, Chantika Maulana Arif Murtadho Novriyanti, Tika Prihatonoa, Amal Purwadhi Purwadhi Rani Hardi Ningsih Riki Ristanto Rusdiatin, Ivana Eko Sumartini, Lilis Cucu Sutiyoso, Seneng Tjhia Khie Khiong Toufiq Martin Vivi Kurniati Tjahjadi Wahyudha Ngatiril Lady Widiatmoko, Roso Putranto Willie Japaries Yani Restiani Widjaja, Yani Restiani Yuliawati Kusumaningrum Zulli Nuralita