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All Journal Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) journal of internal medicine E-Jurnal Medika Udayana The Indonesian Biomedical Journal Jurnal Kesehatan Holistic ISM (Intisari Sains Medis) : Jurnal Kedokteran Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research Cermin Dunia Kedokteran Journal of Global Pharma Technology Bali Medical and Wellness Journal Cermin Dunia Kedokteran
Ketut Suryana
Departemen/KSM Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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A Rare Case of Systemic Lupus Erythematosus with Concomitant Inflammatory Bowel Disease: A Diagnostic and Therapeutic Challenge Made Cantika Kumara Dipa; Ketut Suryana
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 4 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i4.1248

Abstract

Background: Systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD) are chronic conditions with complex pathophysiologies. While both diseases can affect the gastrointestinal tract, their co-occurrence is rare and presents unique diagnostic and therapeutic challenges. This case report describes a patient with SLE who developed IBD, highlighting the complexities of managing such cases. Case presentation: A 27-year-old female with a history of SLE presented with hematochezia, abdominal pain, and weight loss. A colonoscopy revealed findings consistent with IBD. The patient's SLE was well-controlled on immunosuppressive therapy, but the addition of IBD required careful medication adjustments to manage both conditions effectively. Conclusion: The coexistence of SLE and IBD is an uncommon but significant clinical scenario. This case underscores the importance of a thorough evaluation of IBD in SLE patients presenting with gastrointestinal symptoms. Furthermore, it emphasizes the need for a multidisciplinary approach to optimize treatment strategies and improve patient outcomes.
Tantangan Terapi Hipernatremia Refrakter pada Pasien dengan Pneumonia Komunitas dan Gagal Ginjal Akut: Sebuah Laporan Kasus. Yusica Maylasari, Ni Putu; Suryana, Ketut
Jurnal Kesehatan Holistic Vol. 10 No. 1 (2026): Jurnal Kesehatan Holistic Volume 10/ Nomor 1/ January 2026
Publisher : Sekolah Tinggi Ilmu Kesehatan RS Husada

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Abstract

Hipernatremia merupakan gangguan elektrolit serius dengan angka mortalitas tinggi, terutama pada pasien dengan gangguan ginjal dan penurunan asupan cairan. Kami melaporkan seorang perempuan berusia 70 tahun dengan penurunan kesadaran, bicara lambat, dan sulit diajak berkomunikasi. Pemeriksaan menunjukkan kadar natrium 163 mmol/L, peningkatan ureum dan kreatinin, serta infiltrat bilateral pada foto toraks dengan kesan pneumonia. Diagnosis ditegakkan sebagai hipernatremia berat disertai Pneumonia Komunitas dan Gagal Ginjal Akut. Terapi awal diberikan infus NaCl 0,9% dilanjutkan dengan Dextrose 5% (D5W) dengan target koreksi tidak melebihi 10–12 mmol/L per 24 jam, disertai pemberian furosemid intravena untuk membantu natriuresis. Pemantauan ketat terhadap elektrolit, diuresis, dan fungsi ginjal dilakukan selama perawatan. Setelah lima hari, kadar natrium menurun bertahap menjadi 142 mmol/L dan kesadaran pasien membaik tanpa komplikasi neurologis. Kasus ini menyoroti tantangan terapi hipernatremia refrakter pada pasien dengan infeksi paru dan gangguan ginjal, serta menegaskan pentingnya koreksi cairan bertahap dan kolaborasi multidisipliner untuk mencapai hasil klinis yang optimal.
Co-Authors Anak Agung Yunda Prabundari Astari, Anak Agung Ayu Mita Bambang S. Purwoko Gotama, Yovita Harbanu H Mariyono I B Ngurah Rai I Dewa Made Sukrama I Gede Pande Sastrawan I GN Eka Imbawan I Ketut Agus Somia I Made Bakta I Made Sudarmaja I Wayan Agus Jaya Santika I Wayan Putu Sutirta Yasa I.B. Aditya Nugraha Ida Bagus Putra Manuaba Kadek Ena Septiani Surya Puspita Sari Kadek Surya Atmaja Ketut Suardamana Ketut Suardamana Ketut Tuti Parwati Merati Luh Nyoman Arya Wisma Ariani Made Cantika Kumara Dipa Made Swastika Adiguna Nugraha, I.B. Aditya Putu Dyah Ayu Saraswati Reny S.P. Duarsa Rudi Wisaksana Tjokorda Istri Anom Saturti Wayan Wahyu Semara Putra Wulansari Manuaba, Ida Ayu Ratih Yesicha Kurniawati Yuriawantini - Yusica Maylasari, Ni Putu