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BIOAKTIFITAS ANTIINFLAMASI EKTRAK METANOL RIMPANG SIJANGKANG (Hornstedtia scyphifera var. Fusiformis Holttum) TERHADAP TIKUS PUTIH JANTAN Mevy Trisna; Renatalia Fika; Ilza Fitri Handayani; Ainun Naim; Muhajri Agusfina
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.78

Abstract

An investigation examined the anti-inflammatory effects of the methanol extract from the Sijangkang rhizome (Hornstedtia scyphifera var. Fusiformis Holttum) on male albino rats that were induced with 1% carrageenan at a volume of 0.2 ml/rat. The tool used in this test is a Plethysmometer with a working principle using Archimedes' law. A Plethysmometer is a tool used to measure edema volume. The way it works is based on measuring the volume of fluid due to the immersion of the organ whose degree of inflammation is measured into mercury liquid. The working principle is that if an object is dipped into a liquid, the object will get an upward pressure equal to the liquid that is pushed by the object. From the results of the research that has been done, it can be concluded that the methanol extract of sijangkang rhizome has anti-inflammatory activity. The research conducted is an experimental study using 12 test animals consisting of 4 treatment groups, namely 1 negative control group (aquadest), and 3 groups of test substances methanol extract of sijangkang rhizome. The doses used were 2 mg/200 g BW/5 ml, 4 mg/200 g BW/5 ml, and 8 mg/g BW/5 ml. The negative control group and the test group with doses of 4 mg/200 g BW and 2 mg/200 g BW showed a very high and continuously increasing percentage of edema formation. This was due to the fact that the negative control group received only distilled water, while the test group was administered a small amount of the test substance that failed to prevent edema formation. In contrast, the test substance, at a dose of 8 mg/200 g body weight/5 ml, exhibited anti-inflammatory properties.
Formulasi dan Evaluasi Sifat Fisik Sediaan Masker Gel Peel Off Ekstrak Etanol Daun Afrika (Vernonia Amygdalina) Budi Setiawan; Renatalia Fika; Tessa Levia Kasya
Journal Pharma Saintika Vol. 7 No. 2 (2024): April: Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v7i2.45

Abstract

African leaf (vernonia amygdalina) is a plant that has many benefits. The flavonoid content in it has been proven to help inhibit bacterial growth. African leaves that have been extracted thickly are formulated into a Peel off gel mask with a concentration of 6%. 3 Peel off gel mask preparation formulas, namely F1 (PVA 11%), F2 (PVA 13%), F3 (PVA 15%). The resulting masks were evaluated for physical properties including organoleptic tests, pH tests, spreadability tests, homogeneity tests, and drying time tests. The physical properties test of the peel off mask has met mask standards. The organoleptic test showed no signs of physical changes in the preparation after it was formulated into a mask. No fine grains were found in the homogeneity test of the preparation, in the spreadability test it still did not reach the standard due to the increase in base concentration in formulas 2 and 3. The average spreadability test result was 3.125 cm. For the test, the drying time for formulas 1, 2 and 3 was 24, 22, 21 minutes. These results have shown that the preparation meets the standards for drying preparations and is in accordance with the skin pH standard, namely 4.5-6.5.
Gambaran Peresepan Obat Untuk Pasien Asma Rawat Jalan di Klinik X Dumai Muhajri Agusfina; Renatalia Fika; Ainun Naim; Annisa Juwita Dalimunthe
Journal Pharma Saintika Vol. 7 No. 2 (2024): April: Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v7i2.46

Abstract

Asthma is a heterogeneous disease with chronic inflammation of the airways involving inflammatory cells in them, which will respond excessively to a trigger, causing episodic symptoms such as wheezing, shortness of breath, a feeling of pressure in the chest, and coughing (especially in the morning and evening). The aim of this research is to determine the description of drug prescribing for asthma patients at the X Dumai Clinic. This research method was carried out using a retrospective method at the X Dumai Clinic Outpatient Pharmacy during the period July to December 2022. The instruments used were asthma patient prescription sheets and patient prescription data collection sheets. Sampling was carried out using the random sampling method. The number of samples that met the inclusion criteria for this study was 222 patients. Based on gender and age, from the results of research that has been carried out, it is found that the percentage (%) of drug use in asthma patients based on female gender is as high as 122 patients (54.95%) and 100 patients (45.05%) were male. Based on age, it showed that most patients were aged 56-65 years with 59 patients (26.58%). Based on the therapeutic pattern of drug classes, the active drug substance in the drug dosage form showed the highest percentage of 31.98%. Namely Salbutamol. Meanwhile, combination asthma drug prescriptions were 20.27%. Namely Salbutamol and Methylprednisolone.
Gambaran Penggunaan Obat Narkotika di Depo Farmasi Rawat Jalan Rumah Sakit X Kota Pekanbaru Mevy Trisna; Renatalia Fika; Amalia Rahmi
Journal Pharma Saintika Vol. 7 No. 2 (2024): April: Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v7i2.47

Abstract

Narcotics are substances or drugs derived from plants, either synthetic or semi-synthetic, which are used to relieve pain and can cause addiction. Narcotics use requires stricter supervision to avoid drug abuse. The aim of this research is to determine the description of the use of narcotics drugs hospital X Pekanbaru city Outpatient Pharmacy Depot for the period August - October 2022. This research is descriptive and data collection was carried out retrospectively. The sampling technique used was purposive sampling. The results of research on the use of narcotic drugs conducted in the period August – October 2022 showed that based on gender, there were 107 prescriptions for men (48.2%) and 115 prescriptions for women (51.8%). Narcotics use based on age was highest in patients over 45 years old with 84 prescriptions (37.84%). The most commonly prescribed use based on the name of the preparation was codeine 15mg with 2,003 tablets (47.05%). The highest use based on prescriptions from specialist doctors was lung specialist doctors with 102 prescriptions (45.94%).
Evaluasi Waktu Tunggu Pelayanan Resep Apotek X Kota Bukittinggi Ainun Naim; Muhajri Agusfina; Renatalia Fika; Budi Setiawan; Afifah Dwi Asti
Journal Pharma Saintika Vol. 7 No. 2 (2024): April: Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v7i2.49

Abstract

A pharmacy is a pharmaceutical service facility where pharmaceutical practice is carried out by pharmacists. Waiting time for prescription services has an important role in health services. The waiting time is set by the Republic of Indonesia Minister of Health Regulation No. 73 of 2016, which is between 15-30 minutes. This study aims to determine the average waiting time for prescription services at the XPharmacy, Bukittinggi City. The research method used is a quantitative descriptive method and concurrent data collection, that is, research is carried out simultaneously with the services being carried out. The sampling technique used simple random sampling technique and the research was conducted for 2 months. From a total sample of 353 recipes, 231 concocted recipes and 122 non-concocted recipes were obtained. The research results obtained were that the average waiting time for services for concocted prescriptions was 11.23 minutes and for non-concocted prescriptions was 6.13 minutes. The conclusion of this research is that the average waiting time for prescription services at the XPharmacy for compounded and non-concocted medicines is in accordance with the standards set by the Republic of Indonesia Minister of Health Regulation No. 73 of 2016 concerning Pharmaceutical Service Standards in Pharmacies.
Pengembangan Algoritma Kuantum Terinspirasi untuk Penyelesaian Masalah Optimasi Kompleks dalam Ilmu Komputasi Yona Eka Pratiwi; Renatalia Fika
Journal of New Trends in Sciences Vol. 1 No. 2 (2023): Mei: Journal of New Trends in Sciences
Publisher : CV. Aksara Global Akademia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59031/jnts.v1i2.773

Abstract

Quantum-Inspired Algorithms (QIAs) combine principles of quantum computing with classical evolutionary strategies to address complex optimization problems. This research explores the potential of QIAs in improving optimization processes, particularly in combinatorial and multi-objective optimization scenarios. The study focuses on the application of Quantum-Inspired Genetic Algorithms (QIGAs) and Quantum-Inspired Evolutionary Algorithms (QIEAs), assessing their effectiveness in solving classical problems like the Traveling Salesman Problem (TSP) and Minimum Spanning Tree (MST). Through computational simulations, the research compares the time convergence and solution accuracy of QIAs against traditional classical algorithms. The findings demonstrate that QIAs achieve faster convergence rates and higher-quality solutions, with accuracy levels reaching 98-99% of the global optimal solutions, while significantly reducing computational time. These results underline the advantages of QIAs in solving large and complex optimization problems, making them a promising alternative to traditional algorithms. Additionally, QIAs excel in avoiding local minima, a common pitfall of classical methods, due to their ability to explore the solution space more efficiently through quantum principles like superposition and interference. The implications of this study suggest that QIAs can be a valuable tool for tackling real-world optimization challenges, with potential applications in fields such as finance, logistics, telecommunications, and energy management. The research also indicates the necessity for further improvements in quantum-inspired algorithms' scalability and hardware integration, particularly for larger, more intricate optimization problems, to fully realize their potential in practical industrial applications.
Edukasi dan Pemeriksaan IMT (Indeks Masa Tubuh) pada Pondok Pesantren Madinatul Munawarah Kota Bukittinggi Renatalia Fika; Mevy Trisna; Budi Setiawan; Yonrizon Yonrizon; Muhajri Agusfina; Mia Arifka
Komunitas: Hasil Kegiatan Pengabdian Masyarakat Indonesia Vol. 3 No. 3 (2025): Komunitas: Hasil Kegiatan Pengabdian Masyarakat Indonesia
Publisher : Asosiasi Riset Ilmu Tanaman Dan Hewani Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/komunitas.v3i3.239

Abstract

This Community Service is entitled Education and Examination of BMI (Body Mass Index) at the Madinatul Munawarah Islamic Boarding School in Bukittinggi City. Body Mass Index is defined as a person's weight in kilograms divided by height in meters. The purpose of this PKM is to increase awareness and knowledge of students in paying attention to their health regarding BMI, as well as providing education on effective prevention and management methods in maintaining ideal weight and height. This PKM is carried out through health counseling, health checks, and education about healthy lifestyles. The students targeted in this study are from the Madinatul Munawarah Islamic Boarding School in Bukittinggi City. Before the counseling, 26 students were given counseling about their knowledge of BMI / Body Mass Index. Then after the counseling, a health check was also carried out through measuring height and weight. The BMI of the students turned out to show BMI figures that could be categorized as follows: the highest normal category of BMI measurement was 14 people out of 26 participants (54%), and followed by the thin category of 7 people out of 26 participants (27%) while the obese were 5 people out of 26 participants (19%) from the results of calculations using the formula. After counseling and health checks, the students targeted in this study were from the Madinatul Munawarah Islamic Boarding School in Bukittinggi City showed an increase in awareness and knowledge about BMI. Most participants also showed changes in a healthier lifestyle, such as increasing consumption of fruits and vegetables, and doing physical activity regularly. This PKM shows that health education and counseling can increase awareness and knowledge of the students targeted in this study were from the Madinatul Munawarah Islamic Boarding School about BMI. Thus, the students targeted in this community service from the Madinatul Munawarah Islamic Boarding School in Bukittinggi City, can carry out effective prevention and management to reduce the risk of overweight disease.
Pelayanan Edukasi Kesehatan untuk Mencegah Hiperkolesterolemia pada Santri Pondok Pesantren Tahfidz Al Qur’an H.Nur.Abdullah Mevy Trisna; Renatalia Fika; Ainun Naim; Muhajri Agusfina; Zul Efendi
Komunitas: Hasil Kegiatan Pengabdian Masyarakat Indonesia Vol. 3 No. 3 (2025): Komunitas: Hasil Kegiatan Pengabdian Masyarakat Indonesia
Publisher : Asosiasi Riset Ilmu Tanaman Dan Hewani Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/komunitas.v3i3.240

Abstract

This Community Service Program is entitled "Health Education Services to Prevent Hypercholesterolemia in Students at the H. Nur Abdullah Al-Qur'an Memorization Islamic Boarding School." Hypercholesterolemia is a medical condition characterized by high blood cholesterol levels, which can increase the risk of heart disease and stroke. This disease can be prevented and managed with lifestyle changes and appropriate medication. The goal of this Community Service Program is to increase students' awareness and knowledge of hypercholesterolemia and provide education on effective prevention and management methods. This Community Service Program is conducted through health counseling, health checks, and education on healthy lifestyles. The target students in this study were students from the H. Nur Abdullah Al-Qur'an Memorization Islamic Boarding School. Prior to the counseling session, 50 students were given a pre-test questionnaire regarding their knowledge of hypercholesterolemia. After the counseling session, a post-test questionnaire on hypercholesterolemia was administered, which showed an increase in knowledge, as evidenced by the post-test results. Following the counseling and health examinations, the students targeted in this study, from the Nur Abdullah Al- Quran memorization Islamic boarding school, showed increased awareness and knowledge about hypercholesterolemia. Most participants also demonstrated healthier lifestyle changes, such as increasing fruit and vegetable consumption and engaging in regular physical activity. This Community Service Program (PKM) demonstrates that health education and counseling can increase the awareness and knowledge of hypercholesterolemia among the students targeted in this study, from the Nur Abdullah Al-Quran memorization Islamic boarding school. Therefore, the students targeted in this community service session, from the Nur Abdullah Al-Quran memorization Islamic boarding school, can effectively implement prev ention and management strategies to reduce the risk of heart disease and stroke.