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All Journal Pharmacon Jurdimas (Jurnal Pengabdian Kepada Masyarakat) Royal INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Borobudur Pharmacy Review
Ratna Wijayatri
Universitas Muhammadiyah Magelang, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Journal : Jurnal Farmasi Sains dan Praktis

 1 
NANOEMULSION CHARACTERISTICS PREPARATIONS ETHANOL LEAF EXTRACTS IN VARIOUS PLANTS: LITERATURE REVIEW Nora Nur Aini; Ratna Wijayatri; Prasojo Pribadi
Jurnal Farmasi Sains dan Praktis Vol 8 No 3 (September-December 2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v8i3.4786

Abstract

Nanoemulsion is one of the nanotechnology applications that can measure particles 0-100 nm which has control of the release of active ingredients and good sensory properties. Nanoemulsion of ethanol leaf extract in various plants has considerable potential in the utilization of natural materials. The solvent used is an important factor. This research focuses on plant leaf parts with ethanol extract. The purpose of this review is to study, evaluate and analyze literature focused on the characteristics of nanoemulsion preparations of ethanol leaf extracts in various plants related to nanoemulsion components, manufacturing methods, and nanoemulsion preparation characteristics. This research uses the method of literature review or narrative review, the search for published scientific literature is indexed in various databases. Search articles through various databases to ensure that the majority of relevant studies have been identified. Based on the results of the literature review concluded that the most widely used surfactant in the review of these articles is Polysorbat 80 or Tween 80 which is a non-ionic and non-irritative surfactant commonly used in pharmaceutical and cosmetic preparations. Ultrasonification and microfluidation methods are also applied in some articles because they are capable of producing a minimum droplet diameter of 150 to 170 nm..The results of the study of particle size in the article produced particle sizes between 10.9 nm-312.1 nm. Indeks polidispersitas value 0.08-0.7 zeta potential value above +/-30 and EE value shows value above 80%. It can be concluded that the nanoemulsion characteristics of each article meet the requirements and produce stable nanoemulsions.
EFFECT OF GELATIN AS A BINDER ON TURMERIC EXTRACT TABLET FORMULATION Adi Permadi; Iis Wahyuningsih; Sapto Yuliani; Ibdal Satar; Ratna Wijayatri
Jurnal Farmasi Sains dan Praktis Vol 8 No 2 (May-August 2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v8i2.6399

Abstract

In line with the progress of the times in which all aspects of many products are made easy and comfortable for the wearer. The main components for tablet formulations are the fillers, binders, crushers, thinners and lubricants. Among these components, the binders play a key role on the powder cohesion properties during the formation of tablet granules. Due to the effect of gelatin on the tablet properties are positive significant, therefore, this work tries to evaluate the effect of gelatin in the different formulation on the turmeric extract tablets. In this study, turmeric extract tablets were formulated using 15 g of turmeric extract, 35 g of aerosil, 12.8 g of lactose, 1% magnesium stearate, 200 ml of aquadest and gelatin as a binder. To evaluate the effect of gelatin on the tablet formulation, the gelatin was then prepared in different formulation namely 0.1 g (formulation A), 0.2 g (formulation B) and 0.5 g (formulation C), respectivley. Based on the tablet properties, the turmeric tablet with formulation C met the standard requirements of friability less than 1%, the hardness in the range of 4 -8 kg and disintegration time under 15 minutes.
Co-Authors Adi Permadi Alfian Syarifuddin Annisa Nabila Nugraheni Choirunnisa Choirunnisa Eka Puspita Eka Sakti Wahyuningtyas Emelda, Emelda Ermawati Ermawati Ibdal Satar Iis Wahyuningsih Imron Wahyu Hidayat Imron Wahyu Hidayat Kurnia Uji Hartati Kurniasari, Yulinda Nafiatun Nur Nora Nur Aini Prasojo Pribadi Riski afifah Riza Nur Afifah Saniya Puspa Fasya Santi Nurcahya Sapto Yuliani Tisa Fitria Ulya, Lulu Fathnatul Vanny Eka Septiana Yeny Nurchollifah Zulda Sarah Kusumawati